Histopathology of the tongue in a hamster model of COVID-19 by John Coggins, Marina Hosotani Saito, Rebecca Cook, Shinji Urata, Megumi Urata, Nantian Lin Harsell, Wilhelmina Nanrui Tan, Bibiana Toro Figueira, Megan Bradley, Nadia Z. Quadri, Janisah Amirah I. Saripada, Rachel A. Reyna, Junki Maruyama, Slobodan Paessler, Tomoko Makishima

“…SARS-CoV-2 antigen was observed in the vallate papillae taste buds (3–35 dpi) and autonomic ganglia (5–35 dpi), as well as in the serous and mucous salivary glands of the posterior tongue (2–42 dpi). …”
Get full text

Safety of Dupilumab Therapy for Atopic Dermatitis during Pregnancy: A Systematic Review and Meta-analysis by Verónica Sánchez-García, Eva de-Miguel-Balsa, José-Manuel Ramos-Rincón, Isabel Belinchón-Romero

“…To test the robustness of our findings, sensitivity analyses were performed. Fifteen observational studies involving 115 pregnant women with a mean age of 33.46 years (standard deviation [SD] 3.02 were included). …”
Get full text

MicroRNA-22 Promotes Renal Tubulointerstitial Fibrosis by Targeting PTEN and Suppressing Autophagy in Diabetic Nephropathy by Yingying Zhang, Siqi Zhao, Depei Wu, Xingmei Liu, Mingjun Shi, Yuanyuan Wang, Fan Zhang, Jing Ding, Ying Xiao, Bing Guo

“…In this study, our results showed that TIF was observed in DN rats together with obvious autophagy suppression. …”
Get full text

Comparison of simulating visibility using XGBoost and IMPROVE method: a case study in East China by Xin Zhang, Yue Wang, Zibo Zhuang, Yuxi Liu, Chengduo Yuan, Lei Su, Jingyuan Shao, Pak-Wai Chan

“…Throughout the entire study period, the average visibility results obtained by XGB deviate by only 0.07 km from the observed values. These findings underscore the importance of incorporating the XGBoost model into WRF-Chem visibility simulations, as it significantly improves the accuracy of visibility predictions.…”
Get full text

An Exploration of Determinants of Anemia in Pregnant Women at Buakayu Community Health Center Tana Toraja Regency by Erni Yetti R, Zadrak Tombeg, Anto J. Hadi, Sumardi Sudarman, Syamsopyan Ishak, Fitri Rahma Handayani

“…Methods: The study used an observational study with a cross-sectional design. The sample was pregnant women who visited the Buakayu Community Health Center for antenatal examination using an accidental sampling technique for 11 days. …”
Get full text

Lung Matrix Metalloproteinase Activation following Partial Hepatic Ischemia/Reperfusion Injury in Rats by Giuseppina Palladini, Andrea Ferrigno, Vittoria Rizzo, Eleonora Tarantola, Vittorio Bertone, Isabel Freitas, Stefano Perlini, Plinio Richelmi, Mariapia Vairetti

“…No difference in MMPs and MPO was observed in kidney and heart. Conclusions. Although the underlying mechanism needs further investigation, this is the first study in which the MMP activation in a distant organ is reported; this event is probably TNF-alpha-mediated and the lung appears as the first remote organ to be involved in hepatic I/R injury.…”
Get full text

Ion‐Permeable Electrospun Scaffolds Enable Controlled In‐Vitro Electrostimulation Assay of Myoblasts by Serafina Pacilio, Francesco Decataldo, Roberta Costa, Tobias Cramer, Beatrice Fraboni, Giovanna Cenacchi, Maria Letizia Focarete

“…The induction of electric fields orthogonal to the scaffold surface allows for accurately mimicking the excitation‐contraction coupling mechanism observed in native skeletal muscle tissue. This work paves the way for the quantitative study of muscular cell dynamic behavior and physiology, further evaluating therapy effectiveness for muscular pathologies.…”
Get full text

Effects of specimen size and loading rate on the mechanical property of Bentonil-WRK bentonite for engineered barrier system by Ivan Jeff Navea, Jebie Balagosa, Se Hee Han, Seok Yoon, Yun Wook Choo

“…Minimal effect of loading rate was observed on qu and εf. However, increasing loading rate tends to increase E. …”
Get full text

Comparison of handheld rebound tonometry with Goldmann applanation tonometry in children with glaucoma: a cohort study by Catey Bunce, Peng Tee Khaw, John Brookes, Maria Papadopoulos, Amanda Lewis, Poornima Rai, Renata Puertas, Annegret Hella Dahlmann-Noor, Shenille Tabasa-Lim, Ahmed El-Karmouty, Mustafa Kadhim, Nicholas Kloster Wride, Dawn Grosvenor

“…Objective To test agreement of two methods to measure intraocular pressure (IOP): rebound tonometry (RBT) and gold standard Goldmann applanation tonometry (GAT) in children with glaucoma.Design Observational prospective cohort study.Setting Tertiary paediatric glaucoma clinic at a single centre.Participants 102 individuals attending a paediatric glaucoma clinic, mean (SD) age 11.85 (3.17), of whom 53 were male.Primary and secondary outcome measures Intraocular pressure, central corneal thickness, child preference for measurement method.Results Limits of agreement for intraobserver and interobserver were, respectively, (−2.71, 2.98) mm Hg and (−5.75, 5.97) mm Hg. …”
Get full text

Production of an Extract with β-1,4-Xylanase Activity by <i>Fusarium oxysporum</i> f. sp. <i>melonis</i> on a Sonicated Brewer’s Spent Grain Substrate by Irma A. Arreola-Cruz, Rosalba Troncoso-Rojas, Francisco Vásquez-Lara, Nina G. Heredia-Sandoval, Alma R. Islas-Rubio

“…A significant increase in the activity of this enzyme was observed (day 6), especially in the extract obtained using the sonicated BSG substrate (39 U/mL). …”
Get full text

Effects of Kalsis, A Dietary Supplement, on Bone Metabolism in the Ovariectomized Rats by Mercedes Montero, Manuel Díaz-Curiel, David Guede, Jose Ramón Caeiro, Marta Martín-Fernández, Mercedes Rubert, Daisy Navarro, Concepción de la Piedra

“…Kalsis administration attenuated partially bone loss observed by μCT due to ovariectomy. BGP, PINP, and the resorption index (CTX/TRAP) were increased in OVX group. …”
Get full text

Decrease in Circulating Dendritic Cell Precursors in Patients with Peripheral Artery Disease by Daniel Kretzschmar, Ilonka Rohm, Sebastian Schäller, Stefan Betge, Rudin Pistulli, Yevgeniya Atiskova, Hans-R. Figulla, Atilla Yilmaz

“…In patients with PAD, a significant decrease in mDCPs, pDCPs, and tDCPs was observed. In immunostaining, markers indicative for mDCs (CD209: 16 versus 8 cells/0.1 mm2, P=0.02; CD83: 19 versus 5 cells/0.1 mm2, P=0.03) were significantly elevated in femoralis plaques compared to control vessels. …”
Get full text

Ginkgo biloba Extract Improves Insulin Signaling and Attenuates Inflammation in Retroperitoneal Adipose Tissue Depot of Obese Rats by Bruna Kelly Sousa Hirata, Renata Mancini Banin, Ana Paula Segantine Dornellas, Iracema Senna de Andrade, Juliane Costa Silva Zemdegs, Luciana Chagas Caperuto, Lila Missae Oyama, Eliane Beraldi Ribeiro, Monica Marques Telles

“…In addition, a significant increase of both Adipo R1 and IL-10 gene expressions and IR and Akt phosphorylation was also observed, while NF-κB p65 phosphorylation and TNF-α levels were significantly reduced. …”
Get full text

Effect of Isosporiasis Prevention with Toltrazuril on Long-Term Pig Performance by K. Rypula, M. Porowski, J. Kaba, M. Gorczykowski, A. Deniz

“…A similar difference was observed in average body weights of slaughtered animals, being on average 104 kg in Group D and 101 kg in Group K (P<0.01). …”
Get full text

A whole process resilience management practice in coastal engineering by Yingtao Zhou, Yingtao Zhou, Yingtao Zhou, Chenhui Jiang, Yuanshu Jiang, Yu Zhu, Yu Zhu, Yu Zhu, Yan Jin, Xian Wang, Xi Feng, Weibing Feng

“…Previous research has mainly focused on individual coastline types, utilizing observations or numerical models for analysis. However, it often lacks a comprehensive approach that integrates planning, design, and assessment. …”
Get full text

Relationship between Ce3+ 5d1 level, conduction-band bottom, and shallow electron trap level in Gd3Ga5O12:Ce and Gd3Al1Ga4O12:Ce crystals studied via pump-probe absorption spectros... by Mamoru Kitaura, Heishun Zen, Shinta Watanabe, Hirokazu Masai, Kei Kamada, Kyoung-Jin Kim, Akira Yoshikawa, Jumpei Ueda

“…A change in the IR-absorption was observed owing to the generation of free carrier plasma via photoexcitation. …”
Get full text

Chromosome-Level Genome Assembly and Annotation of the Highly Heterozygous <i>Phallus echinovolvatus</i> Provide New Insights into Its Genetics by Mengya An, Ruoxi Liang, Yanliu Chen, Jinhua Zhang, Xiuqing Wang, Xing Li, Guohua Qu, Junfeng Liang

“…Collinear relationships were not observed for 15.38% of the genes in the two haplotypes. …”
Get full text

Improving the quality of design calculations of viscous flow in low-flow centrifugal compressor stages by methods of computational fluid dynamics through reasonable application of... by S. V. Kartashev, Yu. V. Kozhukhov

“…For models with wall functions, the quality of the mesh model and the observance of the dimensionless distance to the wall y+ throughout the calculation domain are particularly important. …”
Get full text

Prenatal inflammation impairs early CD11c-positive microglia induction and delays myelination in neurodevelopmental disorders by Kazuya Fuma, Yukako Iitani, Kenji Imai, Takafumi Ushida, Sho Tano, Kosuke Yoshida, Akira Yokoi, Rika Miki, Hiroyuki Kidokoro, Yoshiaki Sato, Yuichiro Hara, Tomoo Ogi, Kohei Nomaki, Makoto Tsuda, Okiru Komine, Koji Yamanaka, Hiroaki Kajiyama, Tomomi Kotani

“…Notably, a lack of high CD11c+ microglial population has been observed in children with neurodevelopmental disorders. …”
Get full text

Interaction Effects of Lipoprotein Lipase Polymorphisms with Lifestyle on Lipid Levels in a Korean Population: A Cross-sectional Study by Jung-A Pyun, Sunshin Kim, KyungChae Park, Inkyung Baik, Nam H Cho, InSong Koh, Jong-Young Lee, Yoon Shin Cho, Young Jin Kim, Min Jin Go, Eugene Shim, KyuBum Kwack, Chol Shin

“…Interactions between LPL polymorphisms and lifestyle factors (lowest p = 9.6 × 10-4) were also observed on lipid concentrations. These findings suggest that there are interaction effects of LPL polymorphisms with lifestyle variables, including energy intake, fat intake, smoking, and alcohol consumption, as well as effects of LPL polymorphisms themselves, on lipid concentrations in a Korean population.…”
Get full text