The effect of AKT inhibition in α-synuclein-dependent neurodegeneration by Bedri Ranxhi, Zoya R. Bangash, Zachary M. Chbihi, Sokol V. Todi, Sokol V. Todi, Peter A. LeWitt, Peter A. LeWitt, Peter A. LeWitt, Wei-Ling Tsou

“…Here, we investigated the effect of AKT inhibition in a Drosophila model of synucleinopathy. We observed that administration of the AKT inhibitor, A-443654 led to mild improvements in both survival and motor function in flies expressing human α-Syn. …”
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Associations between cerebral blood flow and progression of white matter hyperintensities by Siriluk Thammasart, Danielle J. Harvey, Pauline Maillard, Charles DeCarli, Corinne A. Donnay, Gregory J. Wheeler, Audrey P. Fan, Audrey P. Fan

“…IntroductionIn an aging population, white matter hyperintensities (WMHs), observed on FLAIR MRI sequences, are indicators of cognitive decline, motor impairment, and increased vascular risk. …”
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The correlation between temperature and dengue haemorrhagic fever in Malang Regency – Indonesia: A spatial – temporal analysis by Ali Khaidar, Addin Rizaldi Muhammad, Bangun Sugiharto Septiono, Yuniarno Saudin, Fitria Widiyanto Agnes, Suratman Suratman, Lazuardi Lutfan

“…Dengue cases peaked in 2015 (1,331 cases) and 2016 (1,140 cases), with the highest incidence observed in February 2015 and January 2016. A significant correlation was found between temperature and dengue cases at lag 2-3 months (p<0.05). …”
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Zymography of proteases in honey bees (Apis Mellifera) infected with Nosema ceranae by Doghuzlu Mohammad Afrasiabi, Nabian Sedigheh, Paghaleh Gholam Ali Nehzati, Taheri Mohammad, Asadollahi Zahra, Akhzari Soheila

“…Bands with molecular weights of 25, 35, 48, 63, 75, and 100 kDa were observed. Subsequently, the serine proteases in the bees’ digestive tracts ranged in molecular weight between 23-35 kDa, and the molecular weight of cathepsins was 25 kDa by gelatin zymography. …”
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CD4+CD25highCD127low/-FoxP3+ Regulatory T-Cell Population in Acute Leukemias: A Review of the Literature by M. Niedźwiecki, O. Budziło, E. Adamkiewicz-Drożyńska, D. Pawlik-Gwozdecka, M. Zieliński, L. Maciejka-Kembłowska, T. Szczepański, P. Trzonkowski

“…This proposition results from the fact that in some studies, higher percentage of Treg cells in peripheral blood was demonstrated. However, observations confirming these facts are scarce; thus, extrapolating them to the population of children with hematological malignancies needs to be verified in additional studies.…”
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Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells by Francesco Orio, Giovanna Muscogiuri, Stefano Palomba, Bianca Serio, Mariarosaria Sessa, Valentina Giudice, Idalucia Ferrara, Libuse Tauchmanovà, Annamaria Colao, Carmine Selleri

“…This review summarizes main endocrine disorders reported in literature and observed in our center as consequence of auto- and allo-HSCT and outlines current options for their management. …”
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Characterization of visual cognition in pre-manifest, manifest and reduced penetrance Huntington’s disease by Rocio Del Pino, Maria Ángeles Acera, Amaia Ortiz de Echevarrría, Beatriz Tijero, Marta Ruiz-Lopez, Johanne Somme, Javier Ruiz-Martínez, Andrea Gabilondo, Ioana M. Croitoru, Lara Pardina, Naia Ayo-Mentxakatorre, Ane Murueta-Goyena, Iñigo Gabilondo, Rosario Sanchez-Pernaute, Tamara Fernández-Valle, Juan Carlos Gómez Esteban

“…Significant differences in visual memory were observed between reduced penetrance and pre-manifest groups (p = .003), with pre-manifest showing worse performance. …”
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Spinal Cord Injury and Pressure Ulcer Prevention: Using Functional Activity in Pressure Relief by May Stinson, Rachel Schofield, Cathy Gillan, Julie Morton, Evie Gardner, Stephen Sprigle, Alison Porter-Armstrong

“…To investigate both the current pressure relieving behaviours of SCI individuals during computer use and the application of an ergonomically adapted computer-based activity to reduce interface pressure. Design. Observational and repeated measures design. Setting. …”
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The combination of polystyrene microplastics and di (2-ethylhexyl) phthalate promotes the conjugative transfer of antibiotic resistance genes between bacteria by Yu Li, Xiaomei Liu, Saisai Guo, Lan Wang, Jingchun Tang

“…By increasing cell membrane permeability and the expression of correlated genes, the combined treatment group showed promoting effects on the transfer of ARGs than that of control, with the highest promoting effects observed at 1 mg/L PS and 0.1 mg/L DEHP, which was 3.0 times higher in ARGs transfer rate than that of control. …”
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Organic compost in promoting growth and photosynthetic performance of Pereskia aculeata Mill. (Cactaceae) saplings by Nina Machado Suzigan, Gustavo dos Santos Cardoso, Nicole Almeida Barbosa, Giulianna Carolina Pincela da Costa, Geovana Gomes, Sara Dias Moura, Mônica Ellen Regis de Oliveira, Luiz Fernandes Cardoso Campos, Hyrandir Cabral de Melo, Letícia de Almeida Gonçalves

“…Mixed linear models were applied to morphological and physiological variables. It was possible to observe that, the higher the amount of organic compost in the substrate, the greater the growth of the shoots that developed from the cuttings, a result reflected primarily in the increased length and number of leaves on the largest branch, and the dry mass of the above-ground part. …”
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Review of Echocardiographic Findings in Patients with Obstructive Sleep Apnea by Radu Sascău, Ioana Mădălina Zota, Cristian Stătescu, Daniela Boișteanu, Mihai Roca, Alexandra Maștaleru, Maria Magdalena Leon Constantin, Teodor Flaviu Vasilcu, Radu Sebastian Gavril, Florin Mitu

“…The left ventricular longitudinal strain is more affected by the presence of obstructive sleep apnea than circumferential strain values. Although the observed OSA-induced changes are subtle, the benefit of a detailed echocardiographic screening for subclinical heart failure in OSA patients on therapy adherence and outcome should be addressed by further studies.…”
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Electrodeposition of 4-Benzenesulfonic Acid onto a Graphite-Epoxy Composite Electrode for the Enhanced Voltammetric Determination of Caffeine in Beverages by Leonardo de A. Furtado, Mariana C. de O. Gonçalves, Carlos V. M. Inocêncio, Edilson M. Pinto, Daniela de L. Martins, Felipe S. Semaan

“…Detection limits for bare electrode and 4-benzenesulfonic modified electrode were observed circa 145 µmol·L−1 and 1.3 µmol·L−1, respectively. …”
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Choroidal and Retinal OCTA Parameters after Scleral Buckling by Siamak Moradian, Mahmoud Dehghan, Morteza Borandeh Seifi, Mohsen Dastmardi, Fatemeh Suri

“…Methods: This retrospective observational study was performed on 84 eyes: 32 eyes in the study group consisting of patients who had undergone SB due to RRD, 32 fellow eyes of the same patients, and 20 normal control eyes. …”
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Genetics of Myasthenia Gravis: A Case-Control Association Study in the Hellenic Population by Zoi Zagoriti, Marianthi Georgitsi, Olga Giannakopoulou, Fotios Ntellos, Socrates J. Tzartos, George P. Patrinos, Konstantinos Poulas

“…No statistically significant differences were observed in the rest of the variants examined. As far as we are aware, this is the first worldwide attempt to address the possible association between IRF-5 and TNFAIP3 common genetic variants and the genetic basis of MG.…”
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Influence of Proton Irradiation on Thin Films of AZO and ITO Transparent Conductive Oxides—Simulation of Space Environment by Katarzyna Ungeheuer, Janusz Rybak, Amelia E. Bocirnea, Denis A. Pikulski, Aurelian C. Galca, Konstanty W. Marszalek

“…We use X-ray diffraction and electron microscopy observations to see the changes in the structure and microstructure of the films. …”
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Serum Prohepcidin Levels Are Lower in Patients with Atrophic Gastritis by Hyung-Keun Kim, Eun-Chul Jang, Ju-Ok Yeom, Sun-Young Kim, Hyunjung Cho, Sung Soo Kim, Hiun-Suk Chae, Young-Seok Cho

“…No correlations were observed between serum prohepcidin levels and the other markers of anemia, such as hemoglobin, serum iron, ferritin, and total iron binding capacity. …”
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Ecological and Functional Changes in the Hindgut Microbiome of Holstein Cows at High Altitudes by Gong Chen, Haibo Lu, Shangzhen Huang, Congcong Zhang, Xiaojuan Ma, Bin Li, Lingling Hou, Qing Xu, Yachun Wang

“…Additionally, significant separation in hindgut microbiota composition between the two groups was observed based on altitude, while parity, days in milk, and age did not show a comparable impact. …”
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Prognosis of urgent initiation of peritoneal dialysis: a systematic review and meta-analysis by Ji He, BaoQiao Wu, Yue Zhang, Limiao Dai, Juan Ji, Yueming Liu, Qiang He

“…Objectives Currently, there is no consensus on the optimal timing for the initiation of peritoneal dialysis (PD) after catheter placement.Design Systematic review and meta-analysis.Exact date of data collection From inception till July 31, 2023.Main outcome measures To assess the outcomes and safety of unplanned PD initiation (<14/7 days after catheter insertion) in cohort studies.Results Fifteen studies involving 3054 participants were included. (1) The risk of unplanned initiation of leakage and Obstruction was no difference in both the break-in period (BI) <14 and BI < 7 groups. (2) Catheter displacement was more likely to occur in the emergency initiation group with BI < 7. (3) No significant differences were observed between the two groups regarding infectious complications. (4) There was no difference in transition to HD between patients with BI < 7 and BI < 14 d.Conclusion Infectious complications of unplanned initiation of peritoneal dialysis did not differ from planned initiation. …”
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White Kupang Flour (Corbula faba hinds), Fish Meal and Coconut Oil Usage on the Broilers Carcass Percentage and Abdominal Fat by Virgy Dzakina Fahrezy, Mirni Lamid, Setiawan Koesdarto, Emy Koestanti Sabdoningrum, Widya Paramita Lokapirnasari, Sunaryo Hadi Warsito

“…The treatment in this study was ration without using white mussel flour (P0), ration using 10% white mussel flour (P1), ration using 12.5% white mussel flour (P2), ration using 15% white mussel flour (P3). Variables observed were carcass percentage and abdominal fat percentage. …”
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Esophageal Clearance Patterns in Normal Older Adults as Documented with Videofluoroscopic Esophagram by Janice Jou, Jason Radowsky, Ronald Gangnon, Elizabeth Sadowski, Stephanie Kays, Jacqueline Hind, Eric Gaumnitz, Andrew Taylor, JoAnne Robbins

“…Intraesophageal reflux was observed more frequently in older males than in their younger counterparts. …”
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