High Levels of Proinflammatory Cytokines, but Not Markers of Tissue Injury, in Unaffected Intestinal Areas from Patients with IBD by Alberto J. León, Emma Gómez, Jose A. Garrote, David Bernardo, Asterio Barrera, Jose L. Marcos, Luis Fernández-Salazar, Benito Velayos, Alfredo Blanco-Quirós, Eduardo Arranz

“…In general, a correlation was observed between mRNA levels of these cytokines and both iNOS and Granzyme B. …”
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Characterization of an Acetogenin-Carrying Nanosuspension and Its Effect on Bacteria of Interest in the Poultry Industry by Brandon A. López-Romero, Gabriela Aguilar-Hernández, Billy M. Hargis, María de Lourdes García-Magaña, Ulises M. López-García, Rosa I. Ortiz-Basurto, Adalberto Zamudio-Ojeda, Juan D. Latorre, Efigenia Montalvo-González

“…Moreover, the NSps morphology was observed by transmission electron microscopy (TEM). …”
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Decrease of PPARδ in Type-1-Like Diabetic Rat for Higher Mortality after Spinal Cord Injury by Cheng-Chia Tsai, Kung-Shing Lee, Sheng-Hsien Chen, Li-Jen Chen, Keng-Fan Liu, Juei-Tang Cheng

“…A lower expression of PPARδ in spinal cords of STZ-diabetic rats was observed. In addition, the survival times in two-week induction diabetes were longer than those in eight-week induction group, which is consistent with the expression of PPARδ in the spinal cord. …”
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Epidemiological perspectives of amyloidosis in Argentina: a cohort study analysing incidence and mortality patterns among a population affiliated to a medical care programme by María Lourdes Posadas-Martínez, Delfina Cirelli, Florencia De Florio, María Adela Aguirre, Elsa Mercedes Nucifora, Patricia Beatriz Sorroche, María Soledad Sáez, Valeria Inés Aliperti, Jimena Vicens, Marcelina Carretero

“…In addition, an increase in the incidence and mortality rate was observed throughout the period studied.Conclusion The results of this study indicate that amyloidosis remains a rare disease but with an increase in incidence in recent years, especially in elderly people. …”
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Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex by Harald Bernhard, Hana Petržílková, Barbora Popelářová, Kamil Ziemkiewicz, Karolina Bartosik, Marcin Warmiński, Laura Tengo, Henri Gröger, Luciano G. Dolce, Cameron D. Mackereth, Ronald Micura, Jacek Jemielity, Eva Kowalinski

“…Our findings pave the way for future research on mRNA maturation in kinetoplastids. Moreover, the observed structural similarities and differences between TbCBC and the mammalian cap-binding complex will be crucial for considering the potential of TbCBC as a target for anti-trypanosomatid drug development.…”
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The haploid induction ability analysis of various mutation of OsMATL and OsDMPs in rice by Siyi Liang, Qin Wen, Wenyu Lu, Guili Yang, Yingyun Yao, Hairong Cai, Jiafeng Wang, Ming Huang, Hui Wang, Tao Guo

“…Furthermore, when OsDMP1 or OsDMP3 was combined with OsMATL, they increased HIR, and an antagonistic relationship was observed between HIR and SSR in HH48 matl4dmp1 and HH48 matl4dmp3 . …”
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Effect of Intensive Blood Pressure Control on Cardiovascular Remodeling in Hypertensive Patients with Nephrosclerosis by Otelio Randall, John Kwagyan, Tamrat Retta, Kenneth Jamerson, Velvie Pogue, Keith Norris, Muluemebet Ketete, Shichen Xu, Tom Greene, Xuelei Wang, Lawrence Agodoa

“…PP increased at a greater rate in the usual than in lower MAP groups (slope ± SE: 1.08 ± 0.15 versus 0.42 ± 0.15 mmHg/year, P=0.002), but not by the antihypertensive treatment assignment. Observations indicate that control to a lower MAP slows the progression of PP, a correlate of cardiovascular remodeling and complications, and may be beneficial to CV health.…”
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Mode-Dependent Loss Equalized Few-Mode Fiber Photonic Lantern by Yingxuan Li, Senyu Zhang, Zhiyong Zhao, Jing Liu, Zhuyixiao Liu, Ming Tang

“…In addition, CCD measurements of all three output ports have been performed on the fabricated devices, well-defined mode field patterns and high mode purity at the C-band can be observed. The proposed novel unconventional photonic lanterns open a new way to obtain simultaneous mode multiplexing / demultiplexing and mode-dependent loss equalization function, which will be greatly beneficial in the few-mode fiber transmission system.…”
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Severe Psychomotor Delay in a Severe Presentation of Cat-Eye Syndrome by Guillaume Jedraszak, Aline Receveur, Joris Andrieux, Michèle Mathieu-Dramard, Henri Copin, Gilles Morin

“…Hence, this is the first report of a severe neurological phenotype in cat-eye syndrome with a typical type 1 small supernumerary marker chromosome. Our observation clearly complicates prognostic assessment, particularly when cat-eye syndrome is diagnosed prenatally.…”
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circ_0001588 Induces the Malignant Progression of Hepatocellular Carcinoma by Modulating miR-874/CDK4 Signaling by Xiaoyun Bin, Yichen Chen, Jiasheng Ma, Renchao Tang, Zhenrong Zhao, Kangxuan Wang, Jianchu Wang

“…Our current study is aimed at investigating the function of circ_0001588 in HCC, which was observed to significantly increase in HCC tissues and cells. …”
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Muscarinic Receptors Types 1 and 2 in the Preoptic-Anterior Hypothalamic Areas Regulate Ovulation Unequally in the Rat Oestrous Cycle by Yadira L. López-Ramírez, Kayro López-Ramírez, Isabel Arrieta-Cruz, Angélica Flores, Luciano Mendoza-Garcés, Raúl A. Librado-Osorio, Roger Gutiérrez-Juárez, Roberto Domínguez, María Esther Cruz

“…The number of m2AChR-immunoreactive cells was significantly higher at 09:00 h on each day of the oestrous cycle in the POA-AHA region, while no changes in the expression profile of m1AChR protein were observed. The ovulation rate in rats treated with PZP on the oestrous day was lower than that in the vehicle group. …”
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Identification of early prediction biomarkers of severity in patients with severe fever with thrombocytopenia syndrome based on plasma proteomics by Qian Zhang, Qian Zhang, Zhengyi Jiang, Nan Jiang, Luchen Shi, Jiaying Zhao, Jie Zhao, Jie Zhao, Ke Ouyang, Ke Ouyang, Huaying Huang, Huaying Huang, Yaqin Zhang, Yan Dai, Nannan Hu, Ping Shi, Yaping Han, Ke Jin, Jun Li

“…A cohort consisting of 190 patients with SFTS was used to develop the predictive model for severe illness and subsequently validate it in a new cohort consisting of 93 patients with SFTS.ResultsA significant increase in plasma proteins associated with various functional clusters, such as the proteasomal protein catabolic process, phagocytosis, and humoral immune response, was observed in severe SFTS patients. High levels of four proteins including NID1, HSP90α, PSMA1, and VCAM1 were strongly correlated with multi-organ damage and disease progression. …”
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Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia by Bingjie Wang, Rajeev K. Naidu, Renyuan Chu, Jinhui Dai, Xiaomei Qu, Hao Zhou

“…Prospective, nonrandomised, observational study. Patients. 90 patients undergoing refractive surgery for myopia were included. 47 eyes underwent SMILE and 43 eyes underwent FS-LASIK. …”
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Ultra-fast highly sensitive flexible infrared detector by A.R. Rymzhina, P. Sharma, V.V. Podlipnov, D.N. Artemyev, K.N. Tukmakov, V.S. Pavelyev, V.I. Platonov, P. Mishra, N. Tripathi

“…A significant effect of silver nitrate particles scattered in the volume of the photodetector sensitive material on its efficiency is observed. The superiority of the photodetector based on TiS2 nanosheets functionalized with silver nitrate is demonstrated. …”
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Clinical Performance of MAGLUMI Diagnostic Tests for the Automated Detection of Dengue Virus by Bo Peng, Zhonggang Fang, Cong Li, Kun Liu, Ting Wang, Ke Huang, Fan Yang, Yalan Huang, Chunli Wu, Yue Li, Dana Huang, Qian Zhang, Yijun Tang, Xiaolian Liu, Wei Rao, Xiaolu Shi

“…It effectively detects various serotypes of dengue virus, with no observed endogenous interference or cross-reactivity. …”
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The Production of an Economical Culture Medium from Apple Pomace for the Propagation of Non-Conventional Cidermaking Yeast Starters by Josefina M. Fontanini, Andrea C. Origone, Marcela P. Sangorrín, Carmen R. Maturano, Christian A. Lopes, M. Eugenia Rodríguez

“…However, the medium with the acid treatment was found to be more suitable for yeast growth, showing, for both strains, higher µmax and biomass production and lower td and λ than that observed for the medium with the alkaline treatment. …”
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Insights on nitrogen/oxygen dual defects synergistic modulated charge transfer across the g-C3N4/TiO2-NTAs heterojunction enhanced photodegradation and gas-sensing performances by Zhufeng Shao, Lue Zhan, Yiman Zhang, Yonglong Zhang, Guoyang Yu, Yunfei Song, Xiaoming Xiu

“…The optimized CN/TONTs-5 nanocomposite was observed to achieve a remarkable 98.3% photodegradation rate of methyl orange under UV–visible light excitation, which was found to outperform CN/TONTs-2 and CN/TONTs-8 by factors of 1.36 and 1.12, respectively. …”
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Decreased Regulatory T Cells in Vulnerable Atherosclerotic Lesions: Imbalance between Pro- and Anti-Inflammatory Cells in Atherosclerosis by Ilonka Rohm, Yevgeniya Atiskova, Stefanie Drobnik, Michael Fritzenwanger, Daniel Kretzschmar, Rudin Pistulli, Jürgen Zanow, Thomas Krönert, Gita Mall, Hans Reiner Figulla, Atilla Yilmaz

“…The following results were observed: in unstable lesions, significantly higher numbers of proinflammatory cells like DCs, T helper cells, cytotoxic T cells, and natural killer cells were detected compared to stable plaques. …”
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Study on the mechanical properties of Ti-6Al-4V alloy with minimal surface structures: effects of different heat treatment temperatures by Kai Qian, Shuangyu Liu, Fulong Zhang, Guihua Hang, Bo Cui, Ziwei Guo, Qiushi Zhang, Wang Binhua

“…The mechanisms underlying these changes were elucidated through fracture morphology analysis, microstructural observation, and finite element simulation. Results indicate that Gyroid porous scaffolds exhibit superior compressive performance compared to Primitive scaffolds, with yield strength inversely related to porosity—lower porosity corresponds to higher yield strength. …”
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Ethnic Differences in Risk Factors for Obesity among Adults in California, the United States by Liang Wang, Jodi Southerland, Kesheng Wang, Beth A. Bailey, Arsham Alamian, Marc A. Stevens, Youfa Wang

“…Differences in risk factors for obesity were also observed: Whites (gender, age, physical activity, smoking, arthritis, and diabetes medicine intake), Latinos (age, arthritis, and diabetes medicine intake), Asians (age, binge drinking, arthritis, and diabetes medicine intake), and African Americans (gender, physical activity, smoking, binge drinking, and diabetes medicine intake). …”
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