Response to: Comment on “Risk Models for Developing Pancreatic Fistula After Pancreatoduodenectomy: Validation in a Nationwide Prospective Cohort” by Thijs J. Schouten, MD, Anne Claire Henry, MD, Francina J. Smits, MD, PhD, Lois A. Daamen, MD, PhD, I. Quintus Molenaar, MD, PhD, Hjalmar C. van Santvoort, MD, PhD

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A Giant Brunneroma Causing Gastrointestinal Bleeding and Severe Anemia Requiring Transfusion and Surgery by Nicola C. Frenkel, Miangela M. Laclé, Inne H. M. Borel Rinkes, Izaak Q. Molenaar, Jeroen Hagendoorn

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The Value of Desmethylclozapine and Serum CRP in Clozapine Toxicity: A Case Report by Khalid Abou Farha, Andre van Vliet, Henderikus Knegtering, Richard Bruggeman

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Paediatric Posttraumatic Cyst-Like Lesions: A Report of Two Cases and Review of the Literature by R. Jansen, F. van Rooijen, J. P. Toirkens, A. T. Besselaar, J. J. Tolk

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A Protocol for Diagnosis and Management of Aortic Atherosclerosis in Cardiac Surgery Patients by Wouter W. Jansen Klomp, George J. Brandon Bravo Bruinsma, Arnoud W. J. Van ’t Hof, Jan G. Grandjean, Arno P. Nierich

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Persistent Inflammation in Pulmonary Granuloma 48 Years after Talcage Pleurodesis, Detected by FDG-PET/CT by J. C. Fanggiday, R. W. Rouse, S. M. Collard, M. J. de Haas, J. M. H. de Klerk

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Biomarkers for Risk Stratification of Neoplastic Progression in Barrett Esophagus by Marjon Kerkhof, Johannes G. Kusters, Herman van Dekken, Ernst J. Kuipers, Peter D. Siersema

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Decentralised ECG monitoring for drug-resistant TB patients in ambulatory settings by M. Mbenga, A. Slyzkyi, V. Mirtskhulava, S. Pak, A. Gebhard, G. Utepkalieva, A. Sagimbekova, M. Adenov, G. Ryskulov

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Pancreatic Cancer – More Familial than You Thought by M. Tascilar, A. C. Tersmette, G. J. A. Offerhaus, R. H. Hruban

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Hypoxia-Inducible Factor-1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae-Induced Pneumosepsis by Natasja A. Otto, Liza Pereverzeva, Valentine Leopold, Ivan Ramirez-Moral, Joris J. T. H. Roelofs, Jeroen W. J. van Heijst, Alex F. de Vos, Tom van der Poll

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American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score: a study protocol for the translation and validation of the Dutch language version by Cornelis H Van der Vlies, Esther M M van Lieshout, Michael H J Verhofstad, Duncan E Meuffels, A Siebe de Boer, Wim E Tuinebreijer, P Ted Den Hoed

“…Descriptive statistics (including floor and ceiling effects), internal consistency, construct validity, reproducibility (ie, test–retest reliability, agreement and smallest detectable change) and responsiveness will be assessed for the AOFAS DLV.Ethics and dissemination This study has been exempted by the Medical Research Ethics Committee (MREC) Erasmus MC (Rotterdam, the Netherlands). Each participant will provide written consent to participate and remain anonymised during the study. …”
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Evaluation of the implementation of personalised outcomes forecasts to optimise supervised exercise therapy in patients with intermittent claudication: a multimethods process evalu... by Philip J van der Wees, Anneroos Sinnige, Thomas J Hoogeboom, Laura H M Marcellis, Andrew Kittelson, Steffie Spruijt, Joep A W Teijink, Anne G E van Bergen

“…Background Personalised outcomes forecasts (POFs) were introduced among physical and exercise therapists in the Netherlands to optimise supervised exercise therapy for patients with intermittent claudication. …”
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Nurse compliance with a protocol for safe injectable medication administration: comparison of two multicentre observational studies by Martine de Bruijne, Peter Spreeuwenberg, Cordula Wagner, Bernadette Schutijser, Joanna Ewa Klopotowska, Irene Jongerden

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Effects of the Proactive Interdisciplinary Self-Management (PRISMA) Program on Online Care Platform Usage in Patients with Type 2 Diabetes in Primary Care: A Randomized Controlled... by Esther du Pon, Nanne Kleefstra, Frits Cleveringa, Ad van Dooren, Eibert R. Heerdink, Sandra van Dulmen

“…Therefore, the objective of the current study was to investigate whether a group education program can improve the use of an online care platform in patients with T2DM treated by primary care providers in the Netherlands. In a randomized controlled trial, patients with T2DM received either PRISMA with usual care or usual care only. …”
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A Dutch Fanconi Anemia FANCC Founder Mutation in Canadian Manitoba Mennonites by Yne de Vries, Nikki Lwiwski, Marieke Levitus, Bertus Kuyt, Sara J. Israels, Fré Arwert, Michel Zwaan, Cheryl R. Greenberg, Blanche P. Alter, Hans Joenje, Hanne Meijers-Heijboer

“…Genealogical investigation into the ancestors of the Dutch patients shows that these ancestors lived in four distinct areas in The Netherlands. We also show that the Dutch and Manitoba Mennonite FANCC c.67delG patients share the same haplotype surrounding this mutation, indicating a common founder.…”
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Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer:... by Joachim G J V Aerts, Sjoerd H van der Burg, Martijn P Lolkema, Sai Ping Lau, Freek R van ’t Land, Marjolein Y V Homs, Casper H J van Eijck

“…This study will determine the safety of DC/anti-CD40 agonistic antibody combination treatment, and treatment-induced tumour-specific immunological responses.Methods and analysis In this open-label, single-centre (Erasmus Univsersity Medical Center, Rotterdam, Netherlands), single-arm, phase I dose finding study, adult patients with metastatic pancreatic cancer with progressive disease after FOLFIRINOX chemotherapy will receive monocyte-derived DCs loaded with an allogeneic tumour lysate in conjunction with a CD40 agonistic antibody. …”
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Orofacial Pain during Mastication in People with Dementia: Reliability Testing of the Orofacial Pain Scale for Non-Verbal Individuals by Merlijn W. de Vries, Corine Visscher, Suzanne Delwel, Jenny T. van der Steen, Marjoleine J. C. Pieper, Erik J. A. Scherder, Wilco P. Achterberg, Frank Lobbezoo

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Production-Induced Subsidence at the Los Humeros Geothermal Field Inferred from PS-InSAR by Eszter Békési, Peter A. Fokker, Joana E. Martins, Jon Limberger, Damien Bonté, Jan-Diederik van Wees

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Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis by Julia Vullings, Juliana P. Vago, Claire E. J. Waterborg, Rogier M. Thurlings, Marije I. Koenders, Peter L. E. M. van Lent, Peter M. van der Kraan, Flavio A. Amaral, Fons A. J. van de Loo

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BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations by Vera P. Mourits, Valerie A. C. M. Koeken, L. Charlotte J. de Bree, Simone J. C. F. M. Moorlag, Wern Cui Chu, Xiaoli Xu, Helga Dijkstra, Heidi Lemmers, Leo A. B. Joosten, Yue Wang, Reinout van Crevel, Mihai G. Netea

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