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31541
Inflammatory and Redox Blood Gene Expression Fingerprint of Severe Obstructive Sleep Apnoea in Patients With Mild Alzheimer’s Disease
Published 2025-02-01“…Leila Romero-ElKhayat,1 Farida Dakterzada,1 Raquel Huerto,1 Anna Carnes-Vendrell,1 Olga Mínguez,2 Montserrat Pujol Sabaté,2 Adriano Targa,3,4 Ferran Barbé,3,4 Elena Milanesi,5,6 Maria Dobre,5 Gina Manda,5 Antonio Cuadrado,5,7– 10 Gerard Piñol-Ripoll1,11 1Unitat de Trastorns Cognitius, Cognition and Behavior Study Group, Universitat de Lleida, IRBLleida, Lleida, 25198, Spain; 2Unitat de Son, Hospital Universitari Santa Maria de Lleida, Lleida, Spain; 3Group of Translational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain; 4Center for Biomedical Research in Respiratory Diseases Network (CIBERES), Madrid, Spain; 5“Victor Babes” National Institute of Pathology, Bucharest, 050096, Romania; 6Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, 050474, Romania; 7Department of Endocrine Physiology and Nervous System, Instituto de Investigaciones Biomédicas “Alberto Sols” UAM-CSIC, Madrid, 28029, Spain; 8Department of Biochemistry, Faculty of Medicine, Autonomous University of Madrid, Madrid, 28049, Spain; 9Neuroscience Section, Instituto de Investigación Sanitaria La Paz (Idipaz), Madrid, 28046, Spain; 10Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, Madrid, 28031, Spain; 11Alzheimer’s Disease and Other Cognitive Disorders Unit, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona – Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, SpainCorrespondence: Gerard Piñol-Ripoll, Cognitive Disorders Unit, Hospital Universitari Santa Maria, Rovira Roure no. 44, Lleida, 25198, Spain, Tel +34-937-727222, Ext. 173, Fax +34-976-727366, Email gerard_437302@hotmail.comIntroduction: Obstructive sleep apnoea (OSA) is the sleep disorder most frequently found in patients with Alzheimer’s disease (AD). …”
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31542
La transformation de l’ancien centre de détention secrète de Derb Moulay Cherif en musée des « années de plomb » (Casablanca, Maroc)
Published 2024-07-01“…Then came the Instance équité et réconciliation (IER), tasked to investigate the truth about human rights violations committed against opponents over a limited period between 1956 and 1999, with the aim of compensating victims, analyzing the institutional causes of human rights violations and proposing reforms to prevent their recurrence. This context of national reconciliation has allowed commemorations in the public arena, previously prohibited. …”
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31543
Polish Historiography of Polish - Lithuanian Union of 20th Century
Published 1998-12-01“…Bardach saw a merging of two states and two nations. Specialists of the Enlightenment were seeking features of Lithuanian statehood even in the 18th century. …”
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31544
Facing migration under adverse conditions: challenges and resilience in the Colombo-Venezuelan border area
Published 2025-01-01“…Legal services were often sought by migrants, mostly in a special advice centre for migrants or from international organizations while their Colombian neighbours resorted mainly to national institutions including the police. For health issues migrants had often to go to private services with out-of-pocket payment while the Colombians accessed the health system through the subsidized or pre-paid health insurance. …”
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31545
‘Queer Reverence’: Aubrey Beardsley’s Venus and Tannhäuser
Published 2019-12-01“…Critics have read the text as an autobiographical reckoning with mortality; as authorial wish-fulfillment; as a self-reflexive satire of Decadence; as an exposé of excess; as a ‘decadent counterpublic’ that critiques nationalism; and as a parodic rewriting of Wagner that seeks to undercut his political and aesthetic legacies. …”
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31546
Persistent Gender and Racial Hierarchies: Marriage Migration and Mixedness in Morocco from the French Protectorate to the Present
Published 2023-07-01“…But emotions are still at the heart of these experiences of intimacy across racial, national and religious borders. Contemporary and historical couples see mixedness as imbued with new opportunities to express their desire for change, for a new way of living and for creativity. …”
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31547
Caesalpinia sappan L. ethyl acetate extract regulated angiogenesis in atherosclerosis by modulating the miR-126/VEGF signalling pathway
Published 2025-02-01“…Materials and methods: Our study first screened for differentially expressed microRNAs (miRNAs) associated with AS using the Gene Expression Omnibus (GEO) public database at the National Center for Biotechnology Information (NCBI) and R language software. …”
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31548
Codicology in Lithuania in 1918-1990: Between Book History and Palaeography
Published 2023-12-01“…The bibliographies, which were started on a national basis, recorded single copies of codices in a variety of languages and included some external features, but the manuscripts did not receive a closer look. …”
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31549
Cohort retention in a pandemic response study: lessons from the SARS-CoV2 Immunity & Reinfection Evaluation (SIREN) study
Published 2025-01-01“…Abstract Background SIREN is a healthcare worker cohort study aiming to determine COVID-19 incidence, duration of immunity and vaccine effectiveness across 135 NHS organisations in four UK nations. Conducting an intensive prospective cohort study during a pandemic was challenging. …”
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31550
Kajian Strategi Pendidikan Vokasi Bidang Teknologi Informasi dan Komunikasi Menghadapi Bonus Demografi
Published 2023-10-01“…Conducting is done by searching research journal articles from Google Scholar by utilizing Boolean operators, namely: "student competence" AND "SMK" and "TIK". Journals that are nationally indexed, having ISSN or E-ISSN are the source of data in this study. …”
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31551
Interleukin-1 Receptor-Associated Kinase-3 Aggravates Neuroinflammatory Injury After Intracerebral Hemorrhage via Activation NF-κB/IL-17A Pathway in Mice
Published 2025-01-01“…Jun Wang,1,* Yulong Li,1,* Chunyu Tan,1,* Jinlian Shao,1 Weitai Tang,2 Quan Kong,3 Wenqianjun Sheng,1 Zhiquan Ding,1 Feng Li,1 Jifeng Piao,1 Dingyi Lv,1 Libin Hu,1 Qinghua Wang,1 Xiaodan Jiang1 1Neuromedicine Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, People’s Republic of China; 2Department of Neurosurgery, The People’s Hospital of Luoding & Affiliated Luoding Hospital of Guangdong Medical University, Luoding, 527200, People’s Republic of China; 3Neurosurgery Department of Zengcheng Campus, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinghua Wang; Xiaodan Jiang, Email wqh1123@126.com; jiangxiao_dan@163.comBackground: Neuroinflammatory reactions are crucial factors in secondary brain damage following intracerebral hemorrhage (ICH). …”
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31552
Evaluation of primary HPV-based cervical screening among older women: Long-term follow-up of a randomized healthcare policy trial in Sweden.
Published 2024-12-01“…The initial phase of the trial, which was the focus of this study, targeted women aged 56 to 61 years old in 2012 to 2014 who were randomized to primary cytology arm (n = 7,401) or primary HPV arm (n = 7,318). We used national registries to identify the subsequent cervical tests and all histopathological diagnoses including ICC before December 31, 2022. …”
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31553
Comparative Analysis of Prediction Models for Trawling Grounds of the Argentine Shortfin Squid <i>Illex argentinus</i> in the Southwest Atlantic High Seas Based on Vessel Position...
Published 2025-01-01“…This study confirms the reliability of vessel position data in identifying fishing ground information and levels, with higher accuracy in some months compared to the fishing log-based model, thereby reducing the data lag associated with fishing logs, which are typically available a year later. Additionally, national-level fishing log data are often confidential, limiting the ability to fully consider fishing activities across the entire fishing ground region, a limitation effectively addressed by AIS vessel position data. …”
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31554
Analyzing the serum biochemical factors that influence early neurological deterioration in ischemic Stroke patients and developing a nomogram prediction model
Published 2025-01-01“…The study's inclusion and exclusion criteria select patients aged 18+ with a first-time diagnosis of IS who undergo lab tests within 24 hours of admission while excluding those with multiple organ dysfunction, sensory impairments, coagulation disorders, or other serious medical conditions. Based on the National Institutes of Health Stroke Scale (NIHSS) in the United States, patients were categorized into two groups: END (n=69) and non-END (n=151). …”
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31555
Clinical Characteristics and Optimization of Empirical Antimicrobial Therapy for Febrile Neutropenia in Patients With Hematologic Malignancies
Published 2025-02-01“…Yuqing Cui,1,2 Xin Liu,1,2 Sizhou Feng1,2 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, People’s Republic of China; 2Tianjin Institutes of Health Science, Tianjin, 300020, People’s Republic of ChinaCorrespondence: Sizhou Feng, Email doctor_szhfeng@163.comPurpose: Since the publication of the 2011 Infectious Diseases Society of America (IDSA) guidelines for empirical treatment of febrile neutropenia (FN), there have been significant shifts in pathogen profiles and emerging challenges in treatment. …”
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31556
Consecutive prediction of adverse maternal outcomes of preeclampsia, using the PIERS-ML and fullPIERS models: A multicountry prospective observational study.
Published 2025-02-01“…In the United Kingdom, the National Institute for Health and Care Excellence (NICE) recommends repeated use of such static models for ongoing assessment beyond the first 48 h. …”
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31557
Divulgação de evidências científicas sobre Práticas Integrativas e Complementares em Saúde
Published 2025-02-01“…Palavras-chave: Difusão de Conhecimento; Saúde Integral; Autocuidado; Saúde Pública Dissemination of scientific evidence about Health Integrative and Complementary Practices Abstract: The Brazilian National Policy on Integrative and Complementary Practices, established in 2006, aims to provide services to the population by the Unified Health System (SUS). …”
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31558
Active ingredients and mechanisms of peony seed blended oil in diabetes treatment using Kunming mice: Insights from GC–MS, network pharmacology, and experimental verification
Published 2025-02-01“…Furthermore, all three oils should meet the national standard GB 2716–2018 for vegetable oils. …”
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31559
Overall Survival of Patients with Metastatic Renal Cell Carcinoma Following the Introduction of Targeted and Immunotherapies: A Norwegian Retrospective, Real-World Registry Data St...
Published 2025-01-01“…The results may provide additional information on the benefits of tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) in clinical practice.Patients and Methods: We performed a longitudinal, retrospective, non-interventional cohort study using data from four national registries. The study included adults diagnosed with mRCC between 1 January 1995 and 31 December 2018. …”
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31560
Health-Related Quality of Life in Long COVID: Mapping the Condition-Specific C19-YRSm Measure Onto the EQ-5D-5L
Published 2025-01-01“…Adam B Smith,1 Darren C Greenwood,1,2 Paul Williams,3 Joseph Kwon,4 Stavros Petrou,4 Mike Horton,5 Thomas Osborne,5 Ruairidh Milne,6 Manoj Sivan5,7,8 On behalf of LOCOMOTION Consortium1Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom; 2Leeds Institute for Data Analytics, University of Leeds, Leeds, UK; 3COVID Assessment and Rehabilitation Service, Hertfordshire Community NHS Trust, Welwyn Garden City, UK; 4Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK; 5Academic Department of Rehabilitation Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; 6Person with Long COVID; Public Health, University of Southampton, Southampton, UK; 7COVID Rehabilitation Service, Leeds Community Healthcare NHS Trust, Leeds, UK; 8National Demonstration Centre of Rehabilitation Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UKCorrespondence: Adam B Smith, Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom, Email a.b.smith@leeds.ac.ukBackground: Long COVID (LC) is a clinical syndrome with persistent, fluctuating symptoms subsequent to COVID-19 infection. …”
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