Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption by Yue Xu, Xiuying Xiao, Chunxiao Ma, Ziyi Wang, Wenxin Feng, Hanyu Rao, Wei Zhang, Ningyuan Liu, Rebiguli Aji, Xiangjun Meng, Wei‐Qiang Gao, Li Li

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Treatment failure and drug resistance among the newly reported HIV-infected patients in Taizhou City from 2020 to 2022 by LI Yan, WU Xuanhe, SHI Lu, LI Guixia, WANG Shanling, WANG Yating, CHEN Tailin, WANG Tingting, XIE Yali, SHEN Weiwei, LIN Haijiang, CHEN Xiaoxiao, HE Na

“…Among the NNRTIs, the degree of resistance to efavirenz and nevirapine was consistent, with a majority (51.9%) of highly drug-resistant. K103N and M184V were the most common mutation sites, but PIs mutations occured less frequently. …”
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25 años de cirugía de Ross: seguimiento y resultados en pacientes reoperados en nuestro centro by Consuelo M. Sisinni-Ganly, Julio C. Lugo-Adán, Francisco Estévez-Cid, Rocío Casais-Pampín, Juan J. Legarra-Calderón

“…The follow-up of these reintervened patients was 18.7 ± 3.1 years (median 19 years, range 9-23), and the mortality during this period was 10% (n = 3): two due to cardiac causes and one due to non-cardiac causes. …”
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Vitamin K‐dependent gamma‐carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGF... by Zheng Wu, Qing Ye, Shan Zhang, Li‐Peng Hu, Xiao‐Qi Wang, Lin‐Li Yao, Lei Zhu, Shu‐Yu Xiao, Zong‐Hao Duan, Xue‐Li Zhang, Shu‐Heng Jiang, Zhi‐Gang Zhang, De‐Jun Liu, Dong‐Xue Li, Xiao‐Mei Yang

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Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade by Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

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Antispermatogenic Activity of the Benzothiazoline Ligand and Corresponding Organoantimony(V) Derivative in Male Albino Rats

“…<p>Triphenylantimony(V) derivative, <mml:math> <mml:msub> <mml:mtext>Ph</mml:mtext> <mml:mtext>3</mml:mtext> </mml:msub> <mml:mtext>Sb</mml:mtext><mml:mrow><mml:mo>(</mml:mo> <mml:mrow> <mml:msup> <mml:mrow> <mml:mtext>OPr</mml:mtext> </mml:mrow> <mml:mtext>i</mml:mtext> </mml:msup> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow><mml:mrow><mml:mo>[</mml:mo> <mml:mrow> <mml:msub> <mml:mrow> <mml:mtext>SC</mml:mtext> </mml:mrow> <mml:mtext>6</mml:mtext> </mml:msub> <mml:msub> <mml:mtext>H</mml:mtext> <mml:mtext>4</mml:mtext> </mml:msub> <mml:mtext>N</mml:mtext><mml:mo>:</mml:mo><mml:mtext>C</mml:mtext><mml:mrow><mml:mo>(</mml:mo> <mml:mrow> <mml:msub> <mml:mrow> <mml:mtext>CH</mml:mtext> </mml:mrow> <mml:mtext>3</mml:mtext> </mml:msub> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow><mml:msub> <mml:mrow> <mml:mtext>CH</mml:mtext> </mml:mrow> <mml:mtext>2</mml:mtext> </mml:msub> <mml:mtext>C</mml:mtext><mml:mrow><mml:mo>(</mml:mo> <mml:mtext>O</mml:mtext> <mml:mo>)</mml:mo></mml:mrow><mml:msub> <mml:mrow> <mml:mtext>CH</mml:mtext> </mml:mrow> <mml:mtext>3</mml:mtext> </mml:msub> </mml:mrow> <mml:mo>]</mml:mo></mml:mrow> </mml:math>, <mml:math> <mml:mtext mathvariant="bold">1b</mml:mtext> </mml:math>, and the corresponding benzothiazoline ligand [1, 2], <mml:math> <mml:mtext>H</mml:mtext><mml:mover accent='true'> <mml:mrow> <mml:msub> <mml:mrow> <mml:mtext>NC</mml:mtext> </mml:mrow> <mml:mtext>6</mml:mtext> </mml:msub> <mml:msub> <mml:mtext>H</mml:mtext> <mml:mtext>4</mml:mtext> </mml:msub> <mml:mtext>SC</mml:mtext> </mml:mrow> <mml:mo stretchy='true'>&#xFE39;</mml:mo> </mml:mover> <mml:mrow><mml:mo>(</mml:mo> <mml:mrow> <mml:msub> <mml:mrow> <mml:mtext>CH</mml:mtext> </mml:mrow> <mml:mtext>3</mml:mtext> </mml:msub> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow><mml:msub> <mml:mtext>CH</mml:mtext> <mml:mtext>2</mml:mtext> </mml:msub> <mml:mtext>C</mml:mtext><mml:mrow><mml:mo>(</mml:mo> <mml:mtext>O</mml:mtext> <mml:mo>)</mml:mo></mml:mrow><mml:msub> <mml:mtext>CH</mml:mtext> <mml:mtext>3</mml:mtext> </mml:msub> </mml:math>, <mml:math> <mml:mtext mathvariant="bold">1a</mml:mtext> </mml:math>, have been tested for their effects on the reproductive system of male albino rats. …”
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Application of Health Education Accurately Linking System combined with case-based leaning in nursing teaching ward round in the encephalopathy clinic (健康教育精准连接系统助手联合基于案例学习模式在脑病科护理... by FU Jinna (付景娜), ZHAO Zijun (赵子珺), YANG Junxing (杨俊行), HU Zhe (胡哲), LYU Jingmin (吕静敏), SONG Ying (宋颖), SUN Yi (孙祎), GAO Jiajia (高佳佳), GENG Qingwen (耿庆文)

“…Objective To evaluate the Health Education Accurately Linking System (HEALS) combined with case-based leaning (CBL)I n nursing teaching ward round in the encephalopathy clinic. …”
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Recruiting Young People for Digital Mental Health Research: Lessons From an AI-Driven Adaptive Trial by Wu Yi Zheng, Artur Shvetcov, Aimy Slade, Zoe Jenkins, Leonard Hoon, Alexis Whitton, Rena Logothetis, Smrithi Ravindra, Stefanus Kurniawan, Sunil Gupta, Kit Huckvale, Eileen Stech, Akash Agarwal, Joost Funke Kupper, Stuart Cameron, Jodie Rosenberg, Nicholas Manoglou, Manisha Senadeera, Svetha Venkatesh, Kon Mouzakis, Rajesh Vasa, Helen Christensen, Jill M Newby

“…The vast majority were recruited via Facebook and Instagram advertising (n=1203; 92%). Pairwise comparisons revealed that the lead institution’s website was more effective in recruiting eligible participants than Facebook (z=3.47; P=.003) and Instagram (z=4.23; P<.001). …”
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ZFP36 Regulates Vascular Smooth Muscle Contraction and Maintains Blood Pressure by Xiuru Cui, Yawei Wang, Hanlin Lu, Lei Wang, Xianwei Xie, Shenghao Zhang, Pavel Kovarik, Shuijie Li, Shanshan Liu, Qunye Zhang, Jianmin Yang, Cheng Zhang, Jinwei Tian, Yan Liu, Wencheng Zhang

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Impact of Addition of a Newtonian Solvent to a Giesekus Fluid: Analytical Determination of Flow Rate in Plane Laminar Motion by Irene Daprà, Giambattista Scarpi, Vittorio Di Federico

“…The ratio <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mrow><mi>U</mi></mrow><mrow><mi>N</mi></mrow></msub><mo>/</mo><mi>U</mi></mrow></semantics></math></inline-formula> between Newtonian and actual mean velocity depends only on the product <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msqrt><mi>β</mi></msqrt><mi>D</mi><mi>e</mi></mrow></semantics></math></inline-formula>, as for other non-Newtonian fluids.…”
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Development and usability testing of a multifaceted intervention to reduce low-value injury care by Mélanie Bérubé, Alexandra Lapierre, Michael Sykes, Jeremy Grimshaw, Alexis F. Turgeon, François Lauzier, Monica Taljaard, Henry Thomas Stelfox, Holly Witteman, Simon Berthelot, Éric Mercier, Catherine Gonthier, Jérôme Paquet, Robert Fowler, Natalie Yanchar, Barbara Haas, Paule Lessard-Bonaventure, Patrick Archambault, Belinda Gabbe, Jason R. Guertin, Yougdong Ouyang, Lynne Moore, the Canadian Traumatic Brain Injury Research Consortium

“…The prototype’s usability was iteratively tested through four focus groups and four think-aloud sessions with trauma decision-makers (n = 18) from seven Level I to Level III trauma centers. …”
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Effectiveness for remission maintenance rate and safety of different rituximab regimens for treating anti-neutrophil cytoplasmic antibody-associated vasculitis in Japan: a J-CANVAS... by Chie Ogita, Kazuteru Noguchi, Jiro Takeuchi, Naoto Azuma, Satoshi Omura, Daiki Nakagomi, Yoshiyuki Abe, Masatoshi Kadoya, Naoho Takizawa, Atsushi Nomura, Yuji Kukida, Naoya Kondo, Yasuhiko Yamano, Takuya Yanagida, Koji Endo, Shintaro Hirata, Tohru Takeuchi, Kunihiro Ichinose, Masaru Kato, Ryo Yanai, Yusuke Matsuo, Yasuhiro Shimojima, Ryo Nishioka, Ryota Okazaki, Tomoaki Takata, Takafumi Ito, Mayuko Moriyama, Ayuko Takatani, Yoshia Miyawaki, Yutaka Kawahito, Toshiko Ito-Ihara, Takashi Kida, Nobuyuki Yajima, Takashi Kawaguchi, Kiyoshi Matsui

“…Compared with the maintenance-only group, the continuous group had a numerically higher proportion of patients in remission after 48 weeks of treatment (100% vs. 83.3%, p = 0.26) and a lower incidence of infection (5.9% vs. 50%, p = 0.04); however, the N in the maintenance phase was small and suspected to have low power. …”
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An Overview of Solar Orbiter Observations of Interplanetary Shocks in Solar Cycle 25 by Domenico Trotta, Andrew Dimmock, Heli Hietala, Xochitl Blanco-Cano, Timothy S. Horbury, Rami Vainio, Nina Dresing, Immanuel Christopher Jebaraj, Francisco Espinosa Lara, Raúl Gómez-Herrero, Javier Rodriguez-Pacheco, Yulia Kartavykh, David Lario, Jan Gieseler, Miho Janvier, Milan Maksimovic, Nasrin Talebpour Sheshvan, Christopher J. Owen, Emilia K. J. Kilpua, Robert F. Wimmer-Schweingruber

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Evaluation of long‐acting cabotegravir safety and pharmacokinetics in pregnant women in eastern and southern Africa: a secondary analysis of HPTN 084 by Sinead Delany‐Moretlwe, Brett Hanscom, Xu Guo, Clemensia Nkabiito, Patricia Mandima, Patricia Ntege Nahirya, Juliet Mpendo, Muchaneta Bhondai‐Mhuri, Nyaradzo Mgodi, Rebecca Berhanu, Jennifer Farrior, Estelle Piwowar‐Manning, Susan L. Ford, Craig W. Hendrix, Alex R. Rinehart, James F. Rooney, Adeola Adeyeye, Raphael J. Landovitz, Myron S. Cohen, Mina C. Hosseinipour, Mark A. Marzinke, the HPTN 084 Study Team

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Acceptability patterns of hypothetic taxes on different types of foods in France by Florian Manneville, Barthélemy Sarda, Emmanuelle Kesse-Guyot, Sandrine Péneau, Bernard Srour, Julia Baudry, Benjamin Allès, Yann Le Bodo, Serge Hercberg, Mathilde Touvier, Chantal Julia

“…Setting: NutriNet-Santé prospective cohort study. Participants: Adults (n 27 900) engaged in the French NutriNet-Santé e-cohort. …”
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MAM‐STAT3‐Driven Mitochondrial Ca+2 Upregulation Contributes to Immunosenescence in Type A Mandibuloacral Dysplasia Patients by Arshad Ahmed Padhiar, Xiaohong Yang, Syed Aqib Ali Zaidi, Zhu Li, Jinqi Liao, Wei Shu, Arif Ali Chishti, Liangge He, Gulzar Alam, Abdullah Faqeer, Ilyas Ali, Shuai Zhang, Ting Wang, Tao Liu, Meiling Zhou, Gang Wang, Yan Zhou, Guangqian Zhou

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Clinical and experimental rationale for using phenylephrine with hypromellose for the treatment of extra accommodation strain in patients with myopia by M.V. Makhova, E.V. Shikh, V.V. Strakhov, D.S. Blinov, G.K. Poluosmak, E.V. Semeleva, E.V. Blinova

“…Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation </p> <p> ³Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation </p> <p> ⁴National Research Nuclear University MEPhI, Moscow, Russian Federation </p> <p> ⁵N.P. Ogarev National Research Mordovia State University, Saransk, Russian Federation </p> <p> <br> </p> <p> <b>Aim</b>: to perform a comparative analysis of the clinical efficacy of 2.5% phenylephrine with and without hypromellose for the treatment of extra accommodation strain in schoolchildren with myopia and to perform an experimental evaluation of the pharmacological effective of active ingredient of the finished dosage form (FDF) of preparations containing 2.5% phenylephrine with and without excipients. …”
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Comparison of clinical metagenomics with 16S rDNA Sanger sequencing for the bacteriological diagnosis of culture-negative samples by Camille d’Humières, Skerdi Haviari, Marie Petitjean, Laurène Deconinck, Signara Gueye, Nathan Peiffer-Smadja, Lynda Chalal, Naima Beldjoudi, Geoffrey Rossi, Yann Nguyen, Charles Burdet, Ségolène Perrineau, Diane Le Pluart, Roza Rahli, Michael Thy, Piotr Szychowiak, Xavier Lescure, Véronique Leflon-Guibout, Victoire de Lastours, Etienne Ruppé

“…In samples negative for 16S rDNA Sanger sequencing (n = 53), CMg identified clinically-relevant bacteria in 10 samples (19 %, 10 patients) with 14 additional bacteria. …”
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Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway by DanDan Liu, Hui Wang, Jialong Li, Siqi Sheng, Shu Wang, Ye Tian

“…Pathway-related protein inhibitors (the autophagy-related inhibitor 3-methyladenine (3-MA), chloroquine (CQ), ROS inhibitor N-acetyl-L-cysteine (NAC) were applied, and autophagosome changes were observed under transmission electron microscopy. …”
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Evaluation of Treatment Outcomes Using dNLR and GNRI in Combination Therapy With Atezolizumab and Bevacizumab for Hepatocellular Carcinoma by Atsushi Naganuma, Satoru Kakizaki, Atsushi Hiraoka, Toshifumi Tada, Takeshi Hatanaka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Kunihiko Tsuji, Toru Ishikawa, Kazuto Tajiri, Hidenori Toyoda, Chikara Ogawa, Hiroki Nishikawa, Takashi Nishimura, Kazuhito Kawata, Hisashi Kosaka, Masashi Hirooka, Yutaka Yata, Hideko Ohama, Hidekatsu Kuroda, Tomomitsu Matono, Tomoko Aoki, Yuki Kanayama, Kazunari Tanaka, Fujimasa Tada, Kazuhiro Nouso, Asahiro Morishita, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Tomomi Okubo, Taeang Arai, Michitaka Imai, Shinichiro Nakamura, Hirayuki Enomoto, Masaki Kaibori, Yoichi Hiasa, Masatoshi Kudo, Takashi Kumada

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