Attitudes of radiologists and interns toward the adoption of GPT-like technologies: a National Survey Study in China by Tianyi Xia, Shijun Zhang, Ben Zhao, Ying Lei, Zebin Xiao, Bingwei Chen, Junhao Zha, Yaoyao Yu, Zhijun Wu, Chunqiang Lu, Tianyu Tang, Yang Song, Yuancheng Wang, Shenghong Ju

“…Most of the respondents (n = 1223, 94.9%) supported adoption of GPT-like technologies. …”
Get full text

How resistant is anammox biofilm against antibiotics: A special insight into anammox response towards fluoroquinolones by Faysal-Al Mamun, Rohit Kumar, Kelvin Ugochukwu Anwuta, Sovik Das, Madis Jaagura, Koit Herodes, Tetyana Kyrpel, Agnieszka Fiszka Borzyszkowska, Anna Zielińska-Jurek, Zane Vincevica-Gaile, Juris Burlakovs, Andrey E. Krauklis, Mohamad Nor Azra, Md Salauddin, Jiexi Zhong, Taavo Tenno, Kai Bester, Ivar Zekker

“…During batch operations that lasted for up to 6 h, the total nitrogen removal efficiency (TNRE) and total nitrogen conversion rate (TNCR) reached a maximum of 93 ± 5 % and 6.97 ± 1.30 mg N g−1 TSS d−1, respectively. Evidently, at higher PhAC levels, the anammox process was active, and up to 75 % PhAC removal efficiency was obtained within 6 h of the batch cycle. …”
Get full text

Maroteaux-Lamy综合征的ARSB基因分析及新突变的致病性鉴定 by 郭东炜, 潘伟绵, 杜敏联, 郭奕斌

“…【结果】 1） 7个家系先证者的基因检测结果分别为：No1： c.574T>C，p.C192R纯合错义突变；No2： c.160G>A/p.D54N（来 自其母）和c.1197C>G/p.F399L（来自其父）的复合杂合子；No3：仅检出c.1072G>A/p.V358M和IVS5as（-27）A> C变异，但酶检和临床表型符合VI型；No4：为c.281C>T，p.S94L（新突变，来自其母）和IVS5as（-27）A>C（来自 其父）的复合杂合子；No5：为c.1197C>G，p.F399L纯合错义突变；No6：为c.1197C>G，p.F399L（来自其母）和 c.1379C>T，p.S460F（新突变，来自其父）的复合杂合子；No7：为c.499G>A，p.G167R（来自其父）和c.1325C> T，p.T442M（来自其母）的复合杂合子。…”
Get full text

Comparative Analysis of CXCR5 Circulating DNA Methylation Levels in Autoimmune Rheumatic Diseases by Yiming Shi, Yingying Qin, Yunshen Li, Ping Jiang, Kai Wei, Jianan Zhao, Yu Shan, Yixin Zheng, Fuyu Zhao, Mi Zhou, Li Li, Yu Shen, Xinliang Lv, Yuejuan Zheng, Shicheng Guo, Qin Ding, Cen Chang, Dongyi He

Get full text

GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth by Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Michael G Rosenblum, Brian Aguirre, Cheng-Hsiang Lu, Anubhav Chandla, Nidhi Kejriwal, Lucia Liu, Ann M Chan, SuYin Kok, Sergio Duarte, David Casero, Madhuri Wadehra

“…The fusion protein rapidly internalized into EMP2+cancer cells and showed in vitro cytotoxicity to cell lines expressing surface EMP2, with half-maximal cytotoxicity (IC50) values below 100 nM for most positive lines. Ex vivo stability at 37°C indicated a half-life exceeding 96 hours while in vivo PK indicated a biexponential plasma clearance, with a moderate initial clearance (t1/2α=18.4 hours) and a much slower terminal clearance rate (t1/2β=73.1 hours). …”
Get full text

Super‐Enhancer‐Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T‐ALL Cell Growth and Survival by Juanjuan Yu, Zimu Zhang, Yanling Chen, Jianwei Wang, Gen Li, Yanfang Tao, Yongping Zhang, Yang Yang, Chenyue Zhang, Tiandan Li, Jia Cheng, Tongtign Ji, Zhongling Wei, Wenjuan Wang, Fang Fang, Wei Jiang, Peipei Chu, Hongli Yin, Di Wu, Xiaolu Li, Xiaodong Wang, Jun‐Jie Fan, Shaoyan Hu, Zhen‐Hong Zhu, Shuiyan Wu, Jun Lu, Jian Pan

Get full text

Integrating 16S rDNA and metabolomics to uncover the therapeutic mechanism of electroacupuncture in type 2 diabetic rats by Zhang Yue, Wang Xiang, Deng Duping, Gong Yuanyuan, Chen Xuanyi, Li Juan, Li Juan, Hong Xiaojuan

“…ObjectiveThis study aimed to investigate the impact of electroacupuncture (EA) on blood glucose levels, gut microbiota, short-chain fatty acids (SCFAs), and glucagon-like peptide-1 (GLP-1) in a rat model of type 2 diabetes mellitus (T2DM).MethodsForty Sprague–Dawley (SD) rats were randomly assigned to five groups (n = 8/group) using a random number table: normal control, T2DM model, electroacupuncture (EA), EA + antibiotics (EA + A), and antibiotics (A). …”
Get full text

SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

“…The two genotypes displayed distinct gene expression patterns of nitric oxide (NO)-related molecules inducible NO synthase (iNos) and arginase (Arg2), insulin receptor-related signaling factors: cluster of differentiation 36 (Cd36), ecto-nucleotide pyrophosphatase/phosphodiesterase (Enpp), protein tyrosine phosphatase N1 (Ptpn1), cytochrome P450 omega-hydroxylase 4A14 (Cyp4a14), acyl-CoA synthetase 1 (Acsl1) and phosphatase and tensin homolog (Pten). …”
Get full text

Cáscaras de Banano (Musa paradisiaca): Uso Potencial como Bioestimulante en el Cultivo de Tomate by Shailili M. Moreno-Morales, Andy A. Palma-Vera, Marisol Rivero-Herrada, Juan José Reyes-Pérez, Luis Tarquino Llerena-Ramos, Wiston J. Morales-Rodríguez, Eduardo Fabián Quinatoa-Lozada

Get full text

Development of a set of monosomic alien addition lines from Gossypium raimondii in Gossypium hirsutum toward breeding applications in cotton by Zhenzhen Xu, Xiaoxi Lu, Wenjie Ding, Wei Ji, Wuzhimu Ali, Heyang Wang, Shan Meng, Qi Guo, Peng Xu, Xianglong Chen, Liang Zhao, Huan Yu, Xinlian Shen

“…Abstract Background Gossypium raimondii Ulbr is a diploid wild cotton (2n = 26, D5D5) that originated in west-central Peru of South America and possesses desirable characteristics that are absent in the Upland cotton G. hirsutum. …”
Get full text

Evaluation de la qualité de vie des femmes souffrant d’une fistule obstétricale à Kinshasa [Evaluation of the quality of life of women with obstetric fistula in Kinshasa] by Jonathan Enguta Mwenzi, Ruth Bukabau Babuya, Francine Manyonga Sabowa

“…Enfin, il y a 7 femmes qui n’ont pas connu de césarienne, 40 ont eu une césarienne et 9 ont eu deux césariennes. …”
Get full text

A universal gelation strategy of bivalent anions to construct nanofibrous lysozyme hydrogels for immunomemory anti‐recurrence of diabetic wound infection by activating the cGAS‐STI... by Aihui Wang, Liqun Li, Liqian Zheng, Bang‐Ping Jiang, Yihao Liu, Rimei Huang, Huimin Qiu, Shichen Ji, Hong Liang, Xing‐Can Shen

Get full text

Exosome‐derived long non‐coding RNA AC010789.1 modified by FTO and hnRNPA2B1 accelerates growth of hair follicle stem cells against androgen alopecia by activating S100A8/Wnt/β‐cat... by Shaojun Chu, Lingling Jia, Yulong Li, Jiachao Xiong, Yulin Sun, Qin Zhou, Dexiang Du, Zihan Li, Xin Huang, Hua Jiang, Baojin Wu, Yufei Li

Get full text

Assessing intrinsic capacity for person‐centred HIV care: a cross‐sectional study in ageing populations in Malaysia and Hong Kong by Reena Rajasuriar, Syaza Hisham, John Son Lim, Jean Yi Cheong, Wen Ying Ho, Siew Hwei Yap, Nurul Syuhada Zulhaimi, Malinee Neelamegam, Catherine Cheung, Vivian Wong, Ruhana Che Yusof, Kejal Hasmukharay, Shahrul Bahyah Kamaruzzaman, Sharifah Faridah Syed Omar, Meng Li Chong, Pui Li Wong, Grace Chung‐Yan Lui

Get full text

Palmitic Acid Accelerates Endothelial Cell Injury and Cardiovascular Dysfunction via Palmitoylation of PKM2 by Yu He, Senlin Li, Lujing Jiang, Kejue Wu, Shanshan Chen, Linjie Su, Cui Liu, Peiqing Liu, Wenwei Luo, Shilong Zhong, Zhuoming Li

Get full text

Examining the therapeutic potential and side effects of calcium channel blockers in mortality and morbidity of patients with stroke: A systematic review of pre-clinical and clinica... by Sevak Hatamian, Asad Abdi, Fatemeh Sadat Seyedi Asl, Armin Tafazolimoghadam, Arian Tavasol, Seyed Ali Mousavi Nejad, Reza Madadi, Zohre Tajabadi, Mina Dehghani, Najmeh Ahmadpoor, Mobina Fathi, Mohammadreza Hajiesmaeili, Navid Nooraei

“…On the other hand, the stroke recovery phase depends on activating calcium channels and N-methyl-D-aspartate (NMDA) receptors. Considering these issues, one of the interdisciplinary challenges of neurology and cardiology is the use of these drugs in hypertensive patients with cerebrovascular accident (CVA) risk and their uses after these events. …”
Get full text

Surface Planarization‐Epitaxial Growth Enables Uniform 2D/3D Heterojunctions for Efficient and Stable Perovskite Solar Modules by Dongxu Lin, Jun Fang, Sibo Li, Zhenye Zhan, Huan Li, Xin Wang, Guanshui Xie, Daozeng Wang, Nuanshan Huang, Haichen Peng, Weiguang Xie, Luis K. Ono, Yabing Qi, Longbin Qiu

Get full text

Prognostic Value of Skull Base Foramen Invasion Subclassification in T Category Modification and Induction Chemotherapy Management for Nasopharyngeal Carcinoma: Post‐Hoc Analysis o... by Siyu Zhu, Shuqi Li, Di Cao, Chao Luo, Zhiying Liang, Shaobo Liang, Guoyi Zhang, Qin Zhao, Guangying Ruan, Lizhi Liu, Gui Fu, Haojiang Li

Get full text

Interpreting Variants of Uncertain Significance in PCD: Abnormal Splicing Caused by a Missense Variant of DNAAF3 by Haixia Zheng, Chongsheng Cheng, Miao He, Wangji Zhou, Yixuan Li, Jinrong Dai, Ting Zhang, Kai‐Feng Xu, Xue Zhang, Xinlun Tian, Yaping Liu

Get full text

Multiresidue Pesticides Analysis of Vegetables in Vietnam by Ultrahigh-Performance Liquid Chromatography in Combination with High-Resolution Mass Spectrometry (UPLC-Orbitrap MS) by Nam Vu-Duc, Trung Nguyen-Quang, Thuy Le-Minh, Xuyen Nguyen-Thi, Tri Manh Tran, Hai Anh Vu, Lan-Anh Nguyen, Tien Doan-Duy, Bui Van Hoi, Cam-Tu Vu, Dung Le-Van, Lan-Anh Phung-Thi, Hong-An Vu-Thi, Dinh Binh Chu

“…Intraday and interday repeatability of the analytical signal (peak area, n=6) of the developed method were below 3% and 10%, correspondingly. …”
Get full text