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The MBH–M∗ Relation up to z ∼ 2 through Decomposition of COSMOS-Web NIRCam Images
Published 2025-01-01Get full text
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Circulating Stress Hormones, Brain Health, and Cognition in Healthy Older Adults: Cross-Sectional Findings and Sex Differences in Age-Well
Published 2025-03-01“…Methods: Baseline data from 132 cognitively unimpaired participants without depression (age, mean ± SD = 74.0 ± 4.0 years, women: n = 80) in the Age-Well trial (NCT02977819) were included. …”
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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context
Published 2025-02-01“…Findings: 271 patients were concurrently randomised to either fluoxetine (n = 120) or no study drug (n = 151). All patients had received at least one COVID-19 vaccine dose and 67% were female (182/271). …”
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The implementation of genome sequencing in rare genetic diseases diagnosis: a pilot study from the Hong Kong genome projectResearch in context
Published 2025-02-01“…The diagnostic yield was significantly higher in probands without prior genetic testing (37%; n = 185) compared to those previously tested, including exome and genome sequencing (23%; n = 335) (p = 0.001). …”
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“CPR Posture” for Hemorrhage Control
Published 2019-02-01“…Les participants ont pu s’entrainer pendant 30 secondes avant de devoir maintenir une pression égale ou supérieure à environ 21 kPa pendant trois minutes. Les participants n’ont pas eu de retour pendant le test. Les résultats du programme ont rapporté le pourcentage de temps pendant la période de trois minutes durant lequel pour la pression était supérieure à environ 21 kPa. …”
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Deep learning helps discriminate between autoimmune hepatitis and primary biliary cholangitis
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Comparative Ethics of Modern Payment Models
Published 2023-01-01“…Gastroenterol Hepatol (N Y). 2016;12(4):240-244.; Cattel D, Eijkenaar F. …”
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Non-Immersive Virtual Reality Exercise Can Increase Exercise in Older Adults Living in the Community and in Long-Term Care: A Randomized Controlled Trial
Published 2025-02-01“…Lisa Sheehy,1 Lalita Bharadwaj,2 Kelsey Annie Nissen,2 Justine L Estey2 1Bruyère Health Research Institute, Ottawa, Ontario, Canada; 2Centre for Innovation and Research in Aging, Fredericton, New Brunswick, CanadaCorrespondence: Lisa Sheehy, Bruyère Health Research Institute, 43 Bruyère St, Ottawa, ON, K1N 5C8, Canada, Tel +01 613 562 6262 ext. 1593, Email lsheehy@bruyere.orgPurpose: To assess the impact of an 8-week non-immersive virtual reality exercise program for older adults on 1) balance, physical function, community integration and quality of life; 2) falls, emergency room visits, hospital and long-term care admissions; 3) quantity of exercise performed; and 4) acceptance of non-immersive virtual reality.Patients and Methods: This prospective, assessor-blinded, randomized controlled trial was carried out on two separate samples of older adults: those living in their own homes (“home-based”) and those living in long-term care (“facility-based”). …”
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Patterns of food preparation in children and adult diets and their associations with demographic and socio-economic characteristics, health and nutritional status, physical activit...
Published 2025-01-01“…Dietary data from a national-representative sample (n = 5005, 3–84 years) of the Portuguese National Food, Nutrition, and Physical Activity Survey (IAN-AF 2015/16) were classified by preparation locations (at or away from home) and analysed via hierarchical clustering. …”
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Sublimed C60 for efficient and repeatable perovskite-based solar cells
Published 2024-01-01“…Abstract Thermally evaporated C60 is a near-ubiquitous electron transport layer in state-of-the-art p–i–n perovskite-based solar cells. As perovskite photovoltaic technologies are moving toward industrialization, batch-to-batch reproducibility of device performances becomes crucial. …”
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Immuno-PET Imaging of the Programmed Cell Death-1 Ligand (PD-L1) Using a Zirconium-89 Labeled Therapeutic Antibody, Avelumab
Published 2019-04-01“…Results: [ 89 Zr]Zr-DFO-PD-L1 mAb exhibited high affinity (K d ∼ 0.3 nM) and detected moderate PD-L1 expression levels in MDA-MB231 cells. …”
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Copy Number Variations in Short Tandem Repeats Modulate Growth Traits in Penaeid Shrimp Through Neighboring Gene Regulation
Published 2025-01-01“…For instance, a significant association and a negative correlation were found between the copy number of the STR [(A)n] at NW_020872788.1:580574 and body weight. The cytokinesis protein 7-like (LOC113800912) gene, which contains this STR in its splice region, exhibits differential expression associated with body weight variation. …”
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The FIT FIRST 10 dose-response study: evaluation of implementation outcomes
Published 2025-02-01“…Confidence intervals indicated no differences between the two intervention groups for any outcomes. Teachers (n = 32) in both groups rated FF10 moderately acceptable, appropriate, and feasible (3.5–4.0 out of a potential maximum of 5). …”
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بررسی رشد و جذب عناصر معدنی پایهGF677 (هیبرید هلو و بادام) در واکنش به پتانسیل آب در غلظت های مختلف آگار در محیط کشت بافت گیاهی...
Published 2016-02-01“…بیشترین غلظت عناصر پر مصرف (N, P, K, Mg, Ca)و کم مصرف (Zn, Fe, Mn, Cu) در پتانسیل آبی 11/0- و 77/0- مگاپاسکال و کمترین غلظت عناصر در پتانسیل آبی 98/0- و 15/1- مگاپاسکال بدست آمد. …”
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Prebiotics as an adjunct therapy for posttraumatic stress disorder: a pilot randomized controlled trial
Published 2025-01-01“…., dysbiosis) which can promote neuroinflammation; thus, modulation of the microbiome could be an alternative or adjunct treatment approach for PTSD.MethodsThe current study was a 12-week, double-blind, placebo-controlled trial seeking to understand if CBT combined with a microbiota-modifying, prebiotic fiber intervention would beneficially impact clinical outcomes in veterans with PTSD (n = 70). This proof-of-concept, pilot trial was designed to assess: (1) the relationship between severity of PTSD symptoms and microbiota composition and SCFA levels (i.e., acetate, propionate, butyrate), (2) if CBT treatment with a concomitant prebiotic fiber intervention would beneficially impact clinical outcomes in veterans with PTSD, (3) evaluate the feasibility and acceptability of a prebiotic intervention as an adjunct treatment to CBT, and (4) assess the impact of treatment on the intestinal microbiota and stool SCFA (i.e., mechanism).ResultsThis study found that PTSD severity may be associated with reduced abundance of taxa capable of producing the SCFA propionate, and that a subset of individuals with PTSD may benefit from a microbiota-modifying prebiotic intervention.ConclusionThis study suggests that targeting the intestinal microbiome through prebiotic supplementation could represent a promising avenue for enhancing treatment outcomes in some individuals with PTSD.Clinical trial registrationhttps://clinicaltrials.gov/, identifier NCT05424146.…”
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