Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells by Yujing Tao, Yujing Tao, Qun Niu, Qun Niu, Yuanqian Yao, Yuanqian Yao, Kaixin Wang, Kaixin Wang, Haijian Dong, Haijian Dong, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Hui Li

“…In this study, we explored the effects and potential mechanisms of Qizhu-Ruogan-Granules (QZRG), a formulation from the Affiliated Hospital of the Chengdu University of TCM, on carbon tetrachloride (CCl4)-induced liver fibrosis in mice.MethodsA total of 40 male C57BL/6J mice were randomly divided into five groups (n = 8 per group), with liver fibrosis induced by injecting 10% CCl4 for 15 weeks. …”
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Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g... by Reza Tohidi, Hoda Javaheri Bargourooshi, Arash Javanmard

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Low-activity [18F]-somatostatin receptor (SSTR) imaging using [18F]SiTATE on a long axial field-of-view PET/CT scanner by Nils F. Trautwein, Eduardo Calderón, Pia M. Linder, Gerald Reischl, Philippe Driessen, Wenhong Lan, Andreas S. Brendlin, Thorben Groß, Helmut Dittmann, Martina Hinterleitner, Christian la Fougère, Fabian P. Schmidt, Lena S. Kiefer

“…Subjective image quality, noise and lesion detectability of n = 122 lesions were rated using a 5-point Likert scale. …”
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Safety of influenza vaccination during pregnancy: a systematic review by Brian Hutton, David Moher, Danielle B Rice, Claire Butler, Andrea C Tricco, Becky Skidmore, Candyce Hamel, Chantelle Garritty, Paul A Khan, Marco Ghassemi, Charlene Soobiah, Leila Esmaeilisaraji, Dianna M Wolfe, Deshayne Fell, Mona Hersi, Nadera Ahmadzai, Alan Michaud, Angela Sinilaite

“…Twenty-nine studies (24 cohort and 5 case–control) evaluated seasonal influenza vaccination (trivalent and/or quadrivalent) versus no vaccination and were the focus of our prioritised syntheses; 34 studies of pandemic vaccines (2009 A/H1N1 and others), combinations of pandemic and seasonal vaccines, and seasonal versus seasonal vaccines were also reviewed. …”
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Impact of protein intake from a caloric-restricted diet on liver lipid metabolism in overweight and obese rats of different sexes by Ying Tian, Jiawei Gong, Zhiyan He, Suwen Peng, Yuping Huan, Hongpeng Cao

“…Compared with the three calorie-restricted groups, the expressions of nuclear sterol-regulatory element-binding protein-2 (nSREBP-2) and 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) involved in cholesterol synthesis and low-density lipoprotein receptor (LDLR) and cholesterol 7-alpha hydroxylase (CYP7A1) involved in cholesterol clearance in the MC group were significantly lower (P < 0.05). …”
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Identification of serum biomarkers for cystic echinococcosis in sheep through untargeted metabolomic analysis using LC–MS/MS technology by Xiao-Xia Wu, Wan-Li Ban, Li-Jiang Wu, Wen-Jing Qi, Mehdi Borhani, Xiao-Ying He, Xiao-Lei Liu, Ming-Yuan Liu, Jing Ding

“…Then, the 1,7-dihydroxyxanthone, 2-methylbutyrylglycine, 3,3-dimethylglutaric acid, 5,12-dihydroxy-6,8,10,14,17-eicosapentaenoic acid, 9-hydroperoxy-10E,12Z,15Z-octadecatrienoic acid, and trimethylamine N-oxide 6 metabolites were selected as diagnostically valuable candidate biomarkers (area under the curve [AUC] > 0.7). …”
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First-year dynamics of the anaerobic microbiome and archaeome in infants’ oral and gastrointestinal systems by Charlotte J. Neumann, Rokhsareh Mohammadzadeh, Pei Yee Woh, Tanja Kobal, Manuela-Raluca Pausan, Tejus Shinde, Victoria Haid, Polona Mertelj, Eva-Christine Weiss, Vassiliki Kolovetsiou-Kreiner, Alexander Mahnert, Christina Kumpitsch, Evelyn Jantscher-Krenn, Christine Moissl-Eichinger

“…In our study, we longitudinally examined the taxonomic and functional dynamics of the oral and gastrointestinal tract (GIT) microbiomes of healthy infants (n = 30) in their first year, focusing on the often-over-looked aspects, the development of archaeal and anaerobic microbiomes. …”
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Nurses' self-efficacy and outcome expectancy in evidence-based practice: Translation, construct validity and internal consistency of the Dutch scales by Peter Hoegen, Michael Echteld, Cindy de Bot, Annemarie de Vos, Derya Demirçay, Mary-Anne Ramis, Lidwine Mokkink, Hester Vermeulen

“…Confirmatory factor analysis (CFA) (n = 769) tested a second-order model for the Self-efficacy scale (Comparative Fit Index (CFI)=0.96, Tucker-Lewis Index (TLI)=0.95, Root Mean Square Error of Approximation (RMSEA)=0.06, Standardized Root Mean Residual (SRMR)=0.04) and a single-factor model for the Outcome Expectancy Scale (CFI=0.99, TLI=0.99, RMSEA=0.06, SRMR=0.01). …”
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Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae by Wei Yu, Peiyao Jia, Xiaobing Chu, Shengjie Li, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Yingchun Xu, Qiwen Yang

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Novel organophosphate esters and their transformation products in offshore sediment from Eastern China: Occurrence, temporal trend, and risk assessment by Meng Gao, Yu Wang, Liman Wei, Siyuan Li, Qiuyue Zhang, Zhongkang Yang, Mohan Bai, Yiming Yao, Lei Wang, Hongwen Sun

“…The total concentrations of Σ15TOPEs, Σ3NOPEs, Σ9Di-OPEs, and Σ7OH-OPEs in surface sediments were 3.16–73.4, n.d.–16.3, 4.48–21.4, and 0.14–0.42 ng g−1, respectively. …”
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Regional-scale precision mapping of cotton suitability using UAV and satellite data in arid environments by Jianqiang He, Yonglin Jia, Yi Li, Asim Biswas, Hao Feng, Qiang Yu, Shufang Wu, Guang Yang, Kadambot.H.M. Siddique

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Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing by Qianwen Ge, Qianwen Ge, Liangxing Fang, Liangxing Fang, Liangxing Fang, Yang Yu, Yang Yu, Yang Yu, Ruanyang Sun, Ruanyang Sun, Xiaoping Liao, Xiaoping Liao, Xiaoping Liao, Peng Zhang, Peng Zhang, Peng Zhang

“…Group 1 vtaA genes were detected in 87.5% (n = 42) of the isolates.ConclusionThis study provides comprehensive insights into the molecular mechanisms responsible for drug resistance in G. parasuis, the characteristics of molecular epidemiology, and the virulence of resistant groups. …”
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The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus by Marieke M. Kuijk, Emma Tusveld, Esther Lehmann, Rob van Dalen, Iñigo Lasa, Hanne Ingmer, Yvonne Pannekoek, Nina M. van Sorge

“…Approximately one-third of S. aureus isolates decorates WTA with a mixture of α1,4- and β1,4-N-acetylglucosamine (GlcNAc), which requires the dedicated glycosyltransferases TarM and TarS, respectively. …”
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Diversity and seasonal variation of zooplankton community in a large deep-water reservoir of Eastern China using eDNA and morphological methods by Lei Hao, Lei Hao, Xinting Xu, Xinting Xu, Yan Zhou, Yan Zhou, Dan Liu, Dan Liu, Jianqiang Shao, Jiayong Pan, Guangxi He, Zhongjun Hu, Zhongjun Hu, Qigen Liu, Qigen Liu

“…The eDNA identified more environmental factors associated with seasonal changes in zooplankton communities than microscopy, including dissolved oxygen (DO), nephelometric turbidity unit (NTU), ammonia nitrogen (NH3-N), and total phosphorus (TP). The eDNA reads of rotifer and crustacean plankton increased linearly with their morphological abundance but not with biomass. …”
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Efecto de dos probióticos en la supervivencia, crecimiento y concentración de proteínas en la hemolinfa de Penaeus vannamei Boone 1931 enfrentado a desbalance iónico by Alexander Javier Basurto Aguirre, Alexandra Elizabeth Bermúdez-Medranda, Yanis Cruz-Quintana, Juan Carlos Vélez-Chica

“…Se utilizó un control a 30 ‰ y tres tratamientos a 2 ‰ (n = 8) con tres réplicas cada uno; todos los tratamientos fueron duplicados y se agregó probióticos (Aquablend C® o HLBAC®) a uno de los duplicados. …”
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Estudio y medición experimental del coeficiente de arrastre del casco de un dron submarino por medio de un túnel de viento by Jesús Eduardo Rivera López, José Luis Arciniega Martínez, Guadalupe Juliana Gutiérrez Paredes, César Francisco Rodríguez Hibert, Cristian Ariel Martínez Cabrera, Carlos Alfonso Juárez Navarro

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Inflammatory Gene Signature Identified by Machine Algorithms Reveals Novel Biomarkers of Coronary Artery Disease by Liu X, Zhang Y, Wang Y, Xu Y, Xia W, Liu R, Xu S

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The Use of Biopsy and “No-Biopsy” Approach for Diagnosing Paediatric Coeliac Disease in the Central European Region by Petra Riznik, Márta Balogh, Piroska Bódi, Luigina De Leo, Jasmina Dolinsek, Ildikó Guthy, Judit Gyimesi, Ágnes Horváth, Ildikó Kis, Martina Klemenak, Berthold Koletzko, Sibylle Koletzko, Ilma Rita Korponay-Szabó, Tomaz Krencnik, Tarcisio Not, Goran Palcevski, Éva Pollák, Daniele Sblattero, István Tokodi, Matej Vogrincic, Katharina Julia Werkstetter, Jernej Dolinsek

“…Data from 653 children (63.9% female, median age: 7 years, range: 7 months-18.5 years) from Croatia, Hungary, Germany, Italy, and Slovenia were analysed. One fifth (n=134) of included children were asymptomatic at diagnosis. …”
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Sex-specific analysis of individual and ski geometry-related risk factors for ACL injuries in recreational alpine skiing: A case-control study by Gerhard Ruedl, Martin Faulhaber, Markus Posch

“…Results A total of 1,817 recreational skiers (49.1% female) participated in this study, of whom 21.6% (n=392, 57.9% female) sustained an ACL injury. The risk of ACL injury was 1.6 times higher in females (95% CI: 1.2-2.0). …”
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Effect of Pre-Emulsified Flaxseed Oil Containing Rutin on the Quality of <i>Nemipterus virgatus</i> Surimi Gel: Gelatinization Properties, Storage Stability, and Protein Digestibil... by Qingguan Liu, Xiaobing Huang, Huanta Ma, Xinyi Qin, Pengzhi Hong, Xiaowen Pi, Chunxia Zhou

“…Compared with the gel group containing only pre-emulsified flaxseed oil, the addition of rutin significantly reduced the levels of volatile base nitrogen (TVB-N) and thiobarbituric acid reactive substances (TBARSs) in the gel and also mitigated the decline in acidity (<i>p</i> < 0.05). …”
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