Histopathological Characterization and Whole Exome Sequencing of Ectopic Thyroid: Fetal Architecture in a Functional Ectopic Gland from Adult Patient by Rosalinda Yasato Camargo, Cristina Takami Kanamura, Celso Ubirajara Friguglietti, Célia Regina Nogueira, Sonia Iorcansky, Alfio José Tincani, Ana Karina Bezerra, Ester Brust, Fernanda Christtanini Koyama, Anamaria Aranha Camargo, Fernanda Orpinelli R. Rego, Pedro Alexandre Favoretto Galante, Geraldo Medeiros-Neto, Ileana Gabriela Sanchez Rubio

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Case Report: Efficacy and safety of recombinant growth hormone therapy in a girl with Loeys–Dietz syndrome by Kamil Dyrka, Aleksander Jamsheer, Michal Bartecki, Waldemar Bobkowski, Malgorzata Pawelec-Wojtalik, Justyna Rajewska-Tabor, Andzelika Tomaszewska, Justyna Balcerzak, Zuzanna Aniol, Marek Niedziela, Monika Obara-Moszynska

“…At age 6, GHD was recognized [the maximum GH after stimulation 7.2 ng/ml; insulin-like growth factor-1 (IGF-1), 35 ng/ml; N: 84–447]. At age 6.5 years, rGH was initiated (height standard deviation score, htSDS −2.4), which continued for up to 14.25 years (htSDS-1.4). …”
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Elevated Serum Extracellular Vesicle‐Packaged SPARC in Hypertension: A Cross‐Sectional Study in a Middle‐Aged and Elderly Population by Xueying Chen, Han Guo, Xinwei Li, Yang Liu, Xinxin Li, Zhengshuo Cui, Huijuan Ma, Jianxun He, Zhechun Zeng, Huina Zhang

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Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy by Coraline Radermecker, Pascale Hubert, Patrick Roncarati, Stephanie Demoulin, Charlotte Pilard, Marie Ancion, Celia Reynders, Thomas Lerho, Diane Bruyere, Alizee Lebeau, Margot Meunier, Marie-Julie Nokin, Elodie Hendrick, Olivier Peulen, Philippe Delvenne, Michael Herfs

“…Regarding its role in cancer development/progression, paradoxical results exist in the literature and it is still unclear whether HMGB1 mainly acts as an oncogene or a tumor suppressor.Methods HMGB1 expression was first assessed in tissue specimens (n=359) of invasive breast, lung and cervical cancer and the two distinct staining patterns detected (nuclear vs cytoplasmic) were correlated to the secretion profile of malignant cells, patient outcomes and the presence of infiltrating immune cells within tumor microenvironment. …”
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睡眠剥夺对正常成年人前庭功能影响的初步研究 by 吴诗欣, 黎志成, 张姝琪, 李凌伟, 吴慧青, 曾祥丽

“…在异常组中，cVEMP有5例为左侧振幅下降（71%），2例为右侧振幅下降（29%）；oVEMP有13例为左侧振幅下降（76%），4例为右侧振幅下降（24%）；④同为正常睡眠状态时，试验组的cVEMP表现与对照组相比均出现P1潜伏期及波间期延长，差异具有统计学意义（<italic>P </italic>&lt;0.05），试验组的oVEMP表现与对照组相比均出现N1潜伏期及波间期延长（<italic>P </italic>&lt;0.05），表现为潜伏期、波间期的延长，余参数未见明显统计学差异（<italic>P </italic>&gt;0.05）。…”
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Coupling Bio-Resonance Neurotechnology (BRNT) and Dual Hemispheric Repetitive Transcranial Magnetic Stimulation (rTMS) Reduces Comorbid Major Depressive Disorder (MDD) and Generali... by Sunder K, Makale MT, Makale M, Bodhanapati J, Murphy KT, Dennen CA, Baron D, Thanos PK, Hanna C, Ashford Jnr JW, Lewandrowski KU, Blum K

“…The current exploratory case study of a small cohort (n=3; f=2 m=1) used novel neurotechnology to treat co-occurring MDD and GAD with a multifaceted intervention that combines the novel bio-resonance neurotechnology (BRNT) referred to as NuCalm®, to restore autonomic nervous system balance and dual hemispheric repetitive transcranial magnetic stimulation (rTMS) of the ipsilateral Dorsal Lateral Prefrontal Cortex (DLPFC) to treat the disrupted structural components of the brain. …”
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No increase is detected and modeled for the seasonal cycle amplitude of <i>δ</i>¹³C of atmospheric carbon dioxide by F. Joos, F. Joos, S. Lienert, S. Lienert, S. Zaehle

“…Disequilibrium fluxes contribute little to the seasonal amplitude of the net land isotope flux north of 40° N but contribute near equally to the isotopic flux associated with growing season net carbon uptake in tropical and Southern Hemisphere (SH) ecosystems, pointing to the importance of monitoring <span class="inline-formula"><i>δ</i>¹³</span>C<span class="inline-formula">_a</span> over these ecosystems. …”
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Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage by Rosemarie D. Mason, Baoshan Zhang, Nicholas C. Morano, Chen-Hsiang Shen, Krisha McKee, Ashley Heimann, Renguang Du, Alexandra F. Nazzari, Shelby Hodges, Tapan Kanai, Bob C. Lin, Mark K. Louder, Nicole A. Doria-Rose, Tongqing Zhou, Lawrence Shapiro, Mario Roederer, Peter D. Kwong, Jason Gorman

“…Despite similar breadth and potency, the two antibodies differ in their residue-level interactions with important apex features, including N160 glycans and apex cavity, with residue 100i of PGT145 (sulfated tyrosine) penetrating ∼7 Å farther than residue 100i of PGDM1400 (aspartic acid). …”
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Evaluating the effectiveness of immediate vs. elective thoracic endovascular aortic repair for blunt thoracic aortic injury by Zhaohui Hua, Baoning Zhou, Wenhao Xue, Zhibin Zhou, Jintao Shan, Lei Xia, Yunpeng Luo, Yiming Chai, Zhen Li

“…Categorical variables were expressed as n (%), and comparisons were made between the 2 groups using the χ2 test or Fisher’s exact test. …”
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Decoding the m6A epitranscriptomic landscape for biotechnological applications using a direct RNA sequencing approach by Chuwei Liu, Heng Liang, Arabella H. Wan, Min Xiao, Lei Sun, Yiling Yu, Shijia Yan, Yuan Deng, Ruonian Liu, Juan Fang, Zhi Wang, Weiling He, Guohui Wan

“…Abstract Epitranscriptomic modifications, particularly N6-methyladenosine (m6A), are crucial regulators of gene expression, influencing processes such as RNA stability, splicing, and translation. …”
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Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective... by Jesper D. Gunst, Jesal Gohil, Johanthan Z. Li, Ronald J. Bosch, Andrea White, Catherine Seamon, Tae-Wook Chun, Beatriz Mothe, Kathleen Gittens, Lauren Praiss, Marie-Angélique De Scheerder, Linos Vandekerckhove, Kevin Escandón, Ann Thorkelson, Timothy Schacker, Devi SenGupta, Christian Brander, Emmanouil Papasavvas, Luis J. Montaner, Javier Martinez-Picado, Ruxandra Calin, Antonella Castagna, Camilla Muccini, Wesley de Jong, Lorna Leal, Felipe Garcia, Rob A. Gruters, Timothy Tipoe, John Frater, Ole S. Søgaard, Sarah Fidler

“…PTC defined as pVL <50 copies/mL at day 84 occurred in 4% (n = 14) of participants (6% early-ART and 1% late-ART). …”
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Comprehensive symptom assessment using Integrated Palliative care Outcome Scale in hospitalized heart failure patients by Yasuhiro Hamatani, Moritake Iguchi, Yurika Ikeyama, Atsuko Kunugida, Megumi Ogawa, Natsushige Yasuda, Kana Fujimoto, Hidenori Ichihara, Misaki Sakai, Tae Kinoshita, Yasuyo Nakashima, Masaharu Akao

“…Of 294 patients (mean age: 77.5 ± 12.0 years, male: 168 patients, New York Heart Association class IV: 96 patients, mean left ventricular ejection fraction [LVEF]: 44%, and median N‐terminal pro B‐type natriuretic peptide [NT‐proBNP] level: 4418 ng/L), the median (IQR) total IPOS score on admission was 19 (12, 27) and they were widely distributed (minimum: 0 – maximum: 52). …”
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Air pollution and health in Eastern India: Findings from a primary survey conducted in West Bengal and Jharkhand by Arup Halder, Aditi Kundu, Arunava Ghoshal

“…Sample Description: The total sample (N) size was 2784 respondents (Jharkhand and West Bengal), with 1456 respondents from West Bengal and 1328 from Jharkhand. …”
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Evaluación del Sistema Acuapónico de Pequeña Escala para la Producción de Tilapia y Lechuga by Delia Jazmín Sánchez-Morales, Juan Enrique Rubiños-Panta, Guillermo Crespo-Pichardo, Cándido Mendoza-Pérez, Ma. de Lourdes Pérez-Ávila, Maruja Peralta-Inga, Cesar Enrique Rubiños-Hernández

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La revitalisation du corse ou l’émergence de projets de société concurrents by Romain Colonna

“…Il y a encore peu en effet, la question de la revitalisation du corse était majoritairement portée et défendue par les mouvements ou associations d’obédience nationaliste. Ce n’est que depuis 2004 que les partis politiques « traditionnels » se sont véritablement emparés de la question et que les habituels clivages ont pu être en partie dépassés. …”
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La participación social de las personas mayores en regiones enfrentadas al problema demográfico: Extremadura como caso de estudio by Mar Chaves Carrillo, Manuela Caballero Guisado, Lidia G. Domínguez-Párraga

“…En este estudio se siguió una metodología cuantitativa con la aplicación de una encuesta telefónica mediante CATI (Computer Assisted Telephone Interwiew) realizada a personas mayores de 54 años residentes en Extremadura (n=1.401). El tipo de muestreo aplicado fue estratificado por sexo, edad y tamaño de la localidad de residencia, con distribución proporcional al peso poblacional de las dos provincias extremeñas. …”
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The Financial Implications of Pancreatic Surgery: The Hospital Is the Big Winner, Not the Surgeon! by Nitzan Zohar, MD, Avinoam Nevler, MD, Sean P. Maher, Matthew C. Rosenthal, Florence Williams, Wilbur B. Bowne, MD, FACS, Charles J. Yeo, MD, FACS, Harish Lavu, MD, FACS

“…Ninety-seven patients (61%) were diagnosed with adenocarcinoma and 70% (n = 110) underwent PD. The total charges (combined professional and hospital charges) for the cohort encompassing the entire perioperative period were $20,661,759. …”
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JWST Discovery of a Very Fast Biconical Outflow of Warm Molecular Gas in the Nearby Ultraluminous Infrared Galaxy F08572+3915 NW by Kylie Yui Dan, Jerome Seebeck, Sylvain Veilleux, David Rupke, Eduardo Gonzalez-Alfonso, Ismael Garcia-Bernete, Weizhe Liu, Dieter Lutz, Marcio Melendez, Miguel Pereira Santaella, Eckhard Sturm, Francesco Tombesi

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Prevalencia, características y factores asociados con el consumo de alcohol en universitarios peruanos durante la primera etapa de la pandemia de la COVID-19 by William Cabanillas Rojas, Yordanis Enriquez Canto, Luis Menacho Alvirio, Ricardo Murillo Ponte, Giovani Díaz Gervasi

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The efficacy of neoadjuvant immunotherapy and lymphocyte subset predictors in locally advanced esophageal squamous cell carcinoma: A retrospective study by Ruotong Wang, Shaodi Wen, Xiaoyue Du, Jingwei Xia, Bowen Hu, Yihan Zhang, Guoren Zhou, Feng Jiang, Xiaomin Lu, Miaolin Zhu, Xinyu Xu, Bo Shen

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