The antiarthritic effect of CBR‐470‐1 in hypoxic environment is to increase the level of NOD‐like receptor family pyrin domain containing 3 ubiquitination by decreasing phosphoglyc... by Ao Duan, Zemeng Ma, Xiaolong Shao, Zhencheng Xiong, Chaoyi Zhang, Wenzheng Liu, Guanglin Wang, Shouye Hu, Wei Lin

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Comprehensive Structural, Chemical, and Optical Characterization of Cu₂ZnSnS₄ Films on Kapton Using the Automated Successive Ionic Layer Adsorption and Reacti... by Perla J. Vázquez-González, Martha L. Paniagua-Chávez, Lizette A. Zebadua-Chavarria, Rafael Mota-Grajales, C. A. Meza-Avendaño, Enrique Campos-González, A. Escobosa-Echavarría, Yaoqiao Hu, Aldo E. Pérez-Ramos, Manuel-Matuz, Carlos A. Hernández-Gutiérrez

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Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia by Zirong Li, Yi Shu, Deguo Liu, Sheng Xie, Liangbo Xian, Jiaqi Luo, Xiuwen Huang, Haixing Jiang

“…The levels of 5-hydroxytryptamine (5-HT) and aromatic amine-N-acetyltransferase (AANAT) in the cerebrospinal fluid, as well as melatonin levels in the pineal gland, were significantly decreased. …”
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抑制<italic>miR</italic>-<italic>4321</italic>减轻脓毒症相关急性肾脏损伤的作用和机制研究 by 张春敏, 陈飞燕, 杨文敏, 林永敏, 毛碧涛, 陈洁, 武志远, 梁宇峰

“…结果与对照组相比，LPS诱导的HK2细胞中<italic>miR-4321</italic>（<italic>n</italic>=3， <italic>t</italic>=7.154， <italic>P</italic>=0.001 3）表达升高；<italic>miR-4321</italic>-Inhibitor可促进HK2细胞增殖和细胞活力，并降低LPS诱导的IL-1β，IL-6和TNF-α水平的表达。…”
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Use of thymidine kinase 1 autoantibody, thymidine kinase antigen, extracellular protein kinase A autoantibody, and C‐reactive protein for early detection of malignant tumors in dog... by Yoonhee Kim, Wonhee Lee, Byunggak Kim, Bonghwan Jang, Kyung‐Rok Yu, Hong Sook Kim, Minok Ryu, Yein Oh, Kyoungwon Seo, Chul Park, Ulsoo Choi, Dongha Bhang, Hwayoung Youn

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Diagnostic value of macular blood flow in normal tension glaucoma by A.Sh. Zagidullina, V.U. Galimova, A.I. Arslanova, A.R. Nugmanova

“…</p> <p> <b>Patients and Methods: </b>patients aged 45–65 years with early newly diagnosed NTG (35 patients, 35 eyes) or POAG with elevated IOP (43 patients, 43 eyes) and healthy individuals without ocular disorders (n=50) were examined. All patients underwent OCTA by measuring vascular density (VD, %) using the ETDRS grid (central Fovea and Parafovea) and retinal thick-ness using the Angio Retina 3.0 protocol of the Optovue XR Avanti with the AngioVue function (Optovue, USA). …”
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Multidimensional 1-Year Outcomes After Intensive Care Admission for Multisystem Inflammatory Syndrome in Children by Thomas C. Seijbel, BSc, Levi Hoste, MD, Corinne M. P. Buysse, MD, PhD, Karolijn Dulfer, PhD, Filomeen Haerynck, MD, PhD, Matthijs de Hoog, MD, PhD, Naomi Ketharanathan, MD, PhD

“…PATIENTS:. Patients (< 18 yr, n = 58) seen in-person 1-year after PICU admission for MIS-C. …”
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Concentrations and human health risks attributed to potentially toxic elements (PTEs) in water resources in China: Systematic review and meta-analysis by Xiaomei Hui, Anhui Li, Sheng Chang, Aihua Wang, Lu Wang, Chao Li

“…One hundred and twenty-six papers with 237 data-reports (n = 13,083) were included in this study. The rank order of PTEs based on pooled concentration was As (12.6530 µg/l) > Cu (11.1810 µg/l)> Ni (2.4950 µg/l) > Pb (2.0660 µg/l) > Cd (0.5370 µg/l) > Hg (0.3600 µg/l). …”
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Pornography-Watching Disorder and Its Risk Factors Among Young Adults: Cross-Sectional Survey by Csaba Erdős, Oguz Kelemen, Dávid Pócs, Edit Paulik, András Papp, Edina Horváth, Arbel Golan, Krisztián Széll

“…ResultsThe prevalence of PWD in the sample was 4.4% (n=315). Frequent pornography consumption was a significant risk factor, with weekly users (odds ratio [OR] 0.45, 95% CI 0.33-0.62, P<.001), monthly users (OR 0.18, 95% CI 0.11-0.28, P<.001), and less than monthly users (OR 0.05, 95% CI 0.03-0.10, P<.001) showing significantly lower odds compared with daily users as a reference category. …”
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Genotyping of extended-spectrum beta-lactamase-producing Escherichia coli isolated from wastewater of dairy farms in East Java, Indonesia by Fidi Nur Aini Eka Puji Dameanti, Sheila Marty Yanestria, Mustofa Helmi Effendi, Hani Plumeriastuti, Wiwiek Tyasningsih, Emmanuel Nnabuike Ugbo, Rahayu Sutrisno, Muhammad Ali Akramsyah Safri

“…Materials and Methods: Wastewater samples (n = 342) were collected from six major dairy regions in East Java: Pasuruan, Malang, Tulungagung, Blitar, Batu, and Kediri. …”
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CMEs and SEPs During November–December 2020: A Challenge for Real‐Time Space Weather Forecasting by Erika Palmerio, Christina O. Lee, M. Leila Mays, Janet G. Luhmann, David Lario, Beatriz Sánchez‐Cano, Ian G. Richardson, Rami Vainio, Michael L. Stevens, Christina M. S. Cohen, Konrad Steinvall, Christian Möstl, Andreas J. Weiss, Teresa Nieves‐Chinchilla, Yan Li, Davin E. Larson, Daniel Heyner, Stuart D. Bale, Antoinette B. Galvin, Mats Holmström, Yuri V. Khotyaintsev, Milan Maksimovic, Igor G. Mitrofanov

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Self-reported determinants for subjective financial distress: a qualitative interview study with German cancer patients by Eva Winkler, Katja Mehlis, Bastian Surmann, Wolfgang Greiner, Andrea Züger, Viktoria Mathies, Sophie Pauge, Luise Richter, Thomas Ernst, Natalja Menold

“…To better understand subjective financial distress, the presented study explores self-reported determinants for subjective financial distress in German patients with cancer, aiming to inform a new German-language patient-reported outcome measure for determining the financial effects of a tumour disease.Design Semistructured interviews with n=18 patients with cancer were conducted between May 2021 and December 2021. …”
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Use High-Flow Nasal Cannula for Acute Respiratory Failure Patients in the Emergency Department: A Meta-Analysis Study by Cheng-Chieh Huang, Hao-Min Lan, Chao-Jui Li, Tsung-Han Lee, Wen-Liang Chen, Wei-Yuan Lei, Pei-You Hsieh, Mei-Chueh Yang, Chu-Chung Chou, Han-Ping Wu, Yuan-Jhen Syue

“…The secondary outcomes were the mortality rate, intensive care unit (ICU) admission rate, ED discharge rate, need for escalation, length of ED stay, length of hospital stay, and patient dyspnea and comfort scores. Result. Five RCTs (n = 775) were included. There was a decreasing trend regarding the application of HFNC therapy and the intubation rate, but the difference was not statistically significant (RR, 0.53; 95% CI, 0.26–1.09; p=0.08; I2 = 0%). …”
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K-nearest neighbor algorithm for imputing missing longitudinal prenatal alcohol data by Ayesha Sania, Ayesha Sania, Nicolò Pini, Nicolò Pini, Morgan E. Nelson, Michael M. Myers, Michael M. Myers, Lauren C. Shuffrey, Maristella Lucchini, Maristella Lucchini, Amy J. Elliott, Amy J. Elliott, Hein J. Odendaal, William P. Fifer, William P. Fifer

“…AimsThe objective of this study is to illustrate the application of a machine learning algorithm, K Nearest Neighbor (k-NN) to impute missing alcohol data in a prospective study among pregnant women.MethodsWe used data from the Safe Passage study (n = 11,083). Daily alcohol consumption for the last reported drinking day and 30 days prior was recorded using the Timeline Follow back method, which generated a variable amount of missing data per participants. …”
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Laboratory Rotational Spectroscopy Leads to the First Interstellar Detection of Singly Deuterated Methyl Mercaptan (CH2DSH) by Hayley A. Bunn, Silvia Spezzano, Laurent H. Coudert, Jean-Claude Guillemin, Yuxin Lin, Christian P. Endres, Brant Billinghurst, Olivier Pirali, Jes Jørgensen, Valerio Lattanzi, Paola Caselli

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Evaluation of Performance Metrics Required in Proper Selection of SDN Controller for Integrated Satellite-Terrestrial Networks by Oluwatobi A. Ayofe, Mu'azu J. Musa, Zanna M. Abdullahir, Abdoulie M.S. Tekanyi, Aliyu D. Usman, Ezekiel E. Agbon, Emmanuel A. Otsapa, Agburu O. Adikpe, Matthew Iyobhebhe, Paul Thomas Muge

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Identification and functional analysis of Wall-Associated Kinase genes in Nicotiana tabacum by Ling Li, Linggai Cao, Jintao Li, Zhiqiang Zhang, Zhiqiang Zhang, Jie Liu, Zhongying Ren, Jie Zhang, Rengang Wang, Yangfan Miao, Shizhou Yu, Wei Li, Wei Li

“…DiscussionThis study represents the first genome-wide analysis of the WAK gene family in N. tabacum, laying the groundwork for future functional investigations. …”
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Determinants of Dropout From a Virtual Agent–Based App for Insomnia Management in a Self-Selected Sample of Users With Insomnia Symptoms: Longitudinal Study by María Montserrat Sanchez Ortuño, Florian Pecune, Julien Coelho, Jean Arthur Micoulaud-Franchi, Nathalie Salles, Marc Auriacombe, Fuschia Serre, Yannick Levavasseur, Etienne De Sevin, Patricia Sagaspe, Pierre Philip

“…The primary outcome was a binary variable: having dropped out after completing the screening assessment (early dropout) or having completed all the treatment phases (n=551). Multivariable logistic regression analysis was used to identify predictors of dropout among a set of sociodemographic, clinical, and sleep diary variables, and users’ perceptions of the treatment program, collected during the screening interview. …”
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Carboxylated Graphene: An Innovative Approach to Enhanced IgA-SARS-CoV-2 Electrochemical Biosensing by Luciana de Souza Freire, Ariamna María Dip Gandarilla, Yonny Romaguera Barcelay, Camila Macena Ruzo, Barbara Batista Salgado, Ana P. M. Tavares, Francisco Xavier Nobre, Julio Nino de Souza Neto, Spartaco Astolfi-Filho, Ștefan Țălu, Pritesh Lalwani, Niranjan Patra, Walter Ricardo Brito

“…We modified screen-printed carbon electrodes (SPCEs) with CG to immobilize the SARS-CoV-2 N-protein, facilitating targeted detection of IgA antibodies (IgA-SARS-CoV-2). …”
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Intrahepatic CD161hiCD8+T Cell Recruitment Has a Pathogenetic Potential in Chronic HBV Infection by Jianfei Li, Qian Liu, Wanlu Duan, Zhi Duan, Futing Liu, Mengqi Ruan, Qiyin Zong, Hao Zhang, Qiang Zhou, Qin Wang

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