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46901
Early T-Cell Precursor Leukemia Has a Higher Risk of Induction-Related Infection among T-Cell Acute Lymphoblastic Leukemia in Adult
Published 2020-01-01“…We performed a retrospective cohort study for the prevalence and risk predictors of induction-related infection among consecutive T-ALL patients (N=97) enrolled in a PDT-ALL-LBL clinical trial. …”
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46902
A low-protein soybean-free diet improves carcass traits and meat quality and modulates the colonic microbiota in Daweizi pigs
Published 2025-02-01“…The cooking loss of meat decreased, and unsaturated fatty acids such as C22:6 and n−3 PUFA significantly increased in the LPNS group. …”
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46903
Iodine/Chlorine Multi‐Electron Conversion Realizes High Energy Density Zinc‐Iodine Batteries
Published 2025-01-01Get full text
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46904
Metabolic and molecular Characterization, following dietary exposure to DINCH, Reveals new Implications for its role as a Metabolism-Disrupting chemical
Published 2025-02-01“…However, metabolic and molecular effects are not fully understood in vivo.Here, we performed a comprehensive in vivo analysis using C57BL/6N mice to investigate the effects of DINCH on adipose tissue physiology and function. …”
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A mixed-methods observational study of strategies for success in implementation science: overcoming emergency departments hurdles
Published 2025-01-01“…Conclusions Specific determinants of implementation exist in ED settings and require the refining of implementation strategies to overcome site-specific barriers and enhance facilitators. Trial registration n/a.…”
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46907
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Published 2025-02-01“…Excessive consumption of sucrose, in the form of sugar-sweetened beverages, has been implicated in the pathogenesis of metabolic dysfunction‐associated fatty liver disease (MAFLD) and other related metabolic syndromes. The c-Jun N-terminal kinase (JNK) pathway plays a crucial role in response to dietary stressors, and it was demonstrated that the inhibition of the JNK pathway could potentially be used in the treatment of MAFLD. …”
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Understanding the mechanisms of hypoxia-induced tissue damage in fish: The role of GasderminEa/b in Larimichthys crocea
Published 2025-01-01“…Both genes contain a conserved N-terminal pore-forming domain, a C-terminal autoinhibitory domain, and a flexible hinge region. …”
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46910
Correlates of and changes in aerobic physical activity and strength training before and after the onset of COVID-19 pandemic in the UK: findings from the HEBECO study
Published 2022-06-01“…Objectives Understanding changes in moderate to vigorous aerobic physical activity (MVPA) and muscle-strengthening activity (MSA) at the start of the COVID-19 pandemic and their correlates (socio-demographics, health characteristics, living and exercise conditions and pre-pandemic MVPA/MSA) can inform interventions.Design A cross-sectional analysis of retrospective and concurrent data on MVPA/MSA.Setting An online survey in the UK.Participants 2657 adults (weighted n=2442, 53.6% women) participating in the baseline survey (29 April 2020–14 June 2020) of the HEalth BEhaviours during the COVID-19 pandemic (HEBECO) study.Primary and secondary outcome measures Meeting WHO-recommended levels for MVPA/MSA/both (vs meeting neither) during the first lockdown and changes in MVPA/MSA from before to since the COVID-19 pandemic following stratification for pre-pandemic MVPA/MSA.Results A third of adults maintained (30.4%), decreased (36.2%) or increased (33.4%) MVPA. …”
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46911
Nonviral targeted mRNA delivery: principles, progresses, and challenges
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46915
Evaluation of the influence of offshore wind farm noise on the fishes and dolphins in the Pearl River Estuary
Published 2025-01-01“…The pile driving pulses, recorded 30 m from the construction site, had a mean zero-to-peak sound pressure level of 195.1 dB (re 1 μPa) (n = 238), exceeding the hearing thresholds of both fishes and Indo-Pacific humpback dolphins. …”
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Traditional pediatric massage enhanced the skeletal muscle mass in OVA-exposed adolescent rats via regulating SCFAs-FFAR2-IGF-1/AKT pathway
Published 2025-01-01“…ObjectiveThis study aimed to investigate the potential relation between the retarded growth of skeletal muscle (SM) and dysbiosis of gut microbiota (GM) in children with asthma, and to explore the potential action mechanisms of traditional pediatric massage (TPM) from the perspective of regulating GM and short-chain fatty acids (SCFAs) production by using an adolescent rat model of asthma.MethodsMale Sprague-Dawley rats aged 3weeks were divided randomly into the 5 groups (n=6~7) of control, ovalbumin (OVA), OVA + TPM, OVA + methylprednisolone sodium succinate (MP) and OVA + SCFAs. …”
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46919
Should we consider microbiota-based interventions as a novel therapeutic strategy for schizophrenia? A systematic review and meta-analysis
Published 2025-02-01“…Therefore, this meta-analysis investigates whether gut microbiota manipulation can ameliorate psychotic outcomes in patients with schizophrenia receiving pharmacological treatment. Nine studies (n = 417 participants) were selected from 81 records, comprising seven randomized controlled trials and two open-label studies, all with a low risk of bias, included in this systematic review and meta-analysis. …”
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46920
From fairy rings to fairy chemicals: The story from nature phenomenon to commercial application
Published 2024-06-01Get full text
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