Isocitrate Dehydrogenase 1 and 2 Mutations in Pediatric Neuroblastoma Patients by Emre LEVENTOGLU, Gurses SAHIN, Sule YESIL, Ceyhun BOZKURT, Nazmiye YUKSEK, Ali FETTAH, Sule TOPRAK, Burcak KURUCU BILGIN, Emre CAPKINOGLU, Nilgun EROGLU, Sibel AKPINAR TEKGUNDUZ, Ayse Ulya ERTEM

“…Results: A total of 25 patients for whom genetic analysis could be performed were included in the study (60% male, n=15). The mean age was 32.2+-25.9 months (3 days-96 months). …”
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Assessment of Knowledge, Attitude, and Associated Factors of Mpox Among Healthcare Professionals at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2024: A Cros... by Teklehaimanot Kiros, Mulat Erkihun, Mitikie Wondmagegn, Andargachew Almaw, Ayenew Assefa, Ayenew Berhan, Dessie Tegegne, Alemie Fentie, Tegenaw Tiruneh, Birhanemaskal Malkamu, Mahider Shimelis, Eninur Dejen, Birhanu Getie, Shewaneh Damtie, Yenealem Solomon, Bekele Sharew

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Simultaneous estimation of multiple soil properties from vis-NIR spectra using a multi-gate mixture-of-experts with data augmentation by Xiaoqing Wang, Mei-Wei Zhang, Ya-Nan Zhou, Lingli Wang, Ling-Tao Zeng, Yu-Pei Cui, Xiao-Lin Sun

“…., clay, silt, sand, pH (in water), organic content (OC), calcium carbonate (CaCO3), nitrogen (N), phosphorous (P), potassium (K), and cation exchange capacity (CEC). …”
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Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development by Zhijie Hu, Yuqi Zhang, Renfei Cai, Qiuju Chen, Haiyan Guo, Danjun Li, Weidong Lin, Hongxi He, Haibo Wu, Yali Liu, Bin Li, Qianwen Xi, Hongyuan Gao, Jian Zhang, Qifeng Lyu, Yanping Kuang, Xuefeng Lu

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Ventricular assist device implantation in children with a mechanical valve: An ACTION registry analysis by Sabena F. Hussain, MD, MSc, Elyse Miller, MD, Othman Aljohani, MBBS, MPH, Scott Auerbach, MD, David Bearl, MD, Victor Benvenuto, MD, Erica Bonura, MD, Richard L. Crawford, Anna Joong, MD, Jameson Dyal, MD, Christina Hartje-Dunn, MD, Sujit Jana, MD, Sonia Kaushal, MD, Melanie Lynn, MD, Joseph Spinner, MD, Laura Radel, MD, Alexander Raskin, MD, Diana Torpoco-Rivera, MD, Sarah J. Wilkens, MD, MPH, Chet R. Villa, MD

“…Methods: All patients with a history of CHD (n = 433) in the Advanced Cardiac Therapies Improving Outcomes Network database were included in the study (January 2012-January 2023). …”
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Beyond identification of familial hypercholesterolemia: Improving downstream visits and treatments in a large health care system by Harin Lee, Tarun Kadaru, Ruth Schneider, Taylor Triana, Carol Tujardon, Colby Ayers, Mujeeb Basit, Zahid Ahmad, Amit Khera

“…Methods: Individuals at UT Southwestern Medical Center with an LDL-C ≥ 190mg/dL (n = 8368) ever recorded in the EHR were included in an FH registry. …”
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Social determinants and follow-up care after emergency department discharge for traumatic intracranial hemorrhage by Meghan M. Dillan, Joseph Piktel, Adam Perzynski, Mary Jo Roach, Kristen K. Curtis, Yasir Tarabichi, Lance Wilson, Michael L. Kelly

“…We identified patients (n = 117) discharged from the ED with acute tICH, using IDC 9/10 codes and confirmed by imaging review. …”
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Bone metastasis in differentiated thyroid cancer: Spanish multicenter study of clinical characteristics, survival and prognostic factors by Suset Dueñas-Disotuar, Ana Piñar-Gutiérrez, Irene de Lara-Rodríguez, Julia Sastre-Marcos, Emma Anda-Apiñániz, Amelia Oleaga-Alday, JC Galofré, Aida Orois, Victoria Alcázar-Lázaro, Laia Martínez-Guasch, Cecilia Sánchez-Ragnarsson, María Ángeles Gálvez-Moreno, Cristina Familiar-Casado, Tomás Martín-Hernández, Ana R. Romero-Lluch

“…Significant prognostic factors in the multivariate analysis were the presence of lymph node metastases (N1) HR 1.71 (95% CI 1.005-2.098; p=0.048), BM treatment with I131 HR 0.532 (95% CI 0.304-0.931; p=0.027) and age ≥67 years at BM diagnosis HR 1.991 (95% CI 1.142-3.47; p=0.015).ConclusionsSurvival of DTC patients with BM treated in a Spanish cohort was 39.5% at 5 years and 28.5% at 10 years. …”
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Network Medicine‐Based Strategy Identifies Maprotiline as a Repurposable Drug by Inhibiting PD‐L1 Expression via Targeting SPOP in Cancer by Saisai Tian, Mengting Xu, Xiangxin Geng, Jiansong Fang, Hanchen Xu, Xinying Xue, Hongmei Hu, Qing Zhang, Dianping Yu, Mengmeng Guo, Hongwei Zhang, Jinyuan Lu, Chengyang Guo, Qun Wang, Sanhong Liu, Weidong Zhang

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Cranial reconstruction utilizing polymeric implants in two different designs: finite element investigation by Yomna H. Shash

“…The implants were stimulated using two designs (plate and mesh), and different polymeric materials (PEEK and carbon fiber reinforced PEEK 30 and 60%) as titanium substitutes, under 2000 N impact force. Results The results illustrated that plate implants reduced the stresses on the skull and increased the stresses on brain tissues compared to mesh implants. …”
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Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model by Caroline Schoenherr, Caroline Schoenherr, Stefan Pietzsch, Stefan Pietzsch, Cristina Barca, Franziska E. Müller, Frauke S. Bahr, Martina Kasten, Andre Zeug, Sergej Erschow, Christine S. Falk, Evgeni Ponimaskin, James T. Thackeray, Denise Hilfiker-Kleiner, Denise Hilfiker-Kleiner, Melanie Ricke-Hoch

“…The reversible melanoma cancer mouse model (B16F10 cells stably expressing a ganciclovir (GCV)-inducible suicide gene in C57BL/6N mice: B16F10-GCV) allows chemotherapy-free tumor elimination in advanced disease stage and demonstrates almost complete recovery of the mouse heart from cancer-induced atrophy, molecular impairment and heart failure. …”
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Sexual Practices and HIV Prevention Strategies Used by Female Sex Workers in Lagos, Nigeria: An Assessment of the Willingness to Use a Microbicide by Ekama SO, Sheth AN, Ilomuanya MO, Okwuzu JO, Musa AZ, Idigbe I, Ezeobi PM, Oladele DA, Ezechi OC, Salako BL

“…Sabdat Ozichu Ekama,1 Anandi N Sheth,2 Margaret O Ilomuanya,3 Jane Ogoamaka Okwuzu,1 Adesola Zaidat Musa,1 Ifeoma Idigbe,1 Paschal Mbanefo Ezeobi,1 David Ayoola Oladele,1 Oliver Chukwujekwu Ezechi,1 Babatunde Lawal Salako1 1Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, P.M.B 2013, Nigeria; 2Department of Medicine, Division of Infectious Diseases, Emory School of Medicine, Atlanta, GA, USA; 3Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Lagos, Lagos, Surulere, P.M.B 12003, NigeriaCorrespondence: Sabdat Ozichu Ekama, Clinical Sciences Department, Nigerian Institute of Medical Research, 6 Edmund Crescent, Yaba, Lagos, P.M.B 2013, Nigeria, Tel +2348033220908, Email sabdatekama@gmail.comBackground: Female sex workers have a 13-fold higher risk of acquiring HIV than women who do not engage in sex work. …”
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The polarity of high-definition transcranial direct current stimulation affects the planning and execution of movement sequences by Jake J. Son, Tara D. Erker, Thomas W. Ward, Yasra Arif, Peihan J. Huang, Jason A. John, Kellen M. McDonald, Nathan M. Petro, Grant M. Garrison, Hannah J. Okelberry, Kennedy A. Kress, Giorgia Picci, Elizabeth Heinrichs-Graham, Tony W. Wilson

“…Herein, we leverage the excellent spatio-temporal precision of magnetoencephalographic (MEG) imaging to identify the spectral, spatial, and temporal effects of high-definition transcranial direct current stimulation (HD-tDCS) on the neural responses supporting motor control. Participants (N = 67) completed three HD-tDCS visits (anode, cathode, sham), with each involving 20 min of left primary motor cortex stimulation and performance of a simple/complex motor sequencing task during MEG. …”
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Değerler Eğitimi Progamının 6 Yaş Çocuklarına Etkisinin İncelenmesi ve Öğretmen Görüşleri by Çağla Gür, Nurşen Şirin, Münire Şafak, Züleyha Yuvacı, Nurcan Koçak, İlhan Koç

“…Öğretmenler proje değerlendirme formunu aracılığı ile programı ve kendilerine sunulan eğitimi değerlendirmişlerdir. N=72 . Bu araştırmanın deneysel verilerini elde etmek için Gür 2013 tarafından geliştirilen Davranışta Değerler Ölçeği ve araştırmacılar tarafından geliştirilen Kişisel Bilgi Formu kullanılmıştır. …”
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Glycated Serum Protein Genetics and Pleiotropy with Cardiometabolic Risk Factors by Matthew P. Johnson, Ryan Keyho, Nicholas B. Blackburn, Sandra Laston, Satish Kumar, Juan Peralta, Suman S. Thapa, Bradford Towne, Janardan Subedi, John Blangero, Sarah Williams-Blangero

“…The aim of this study was to estimate the heritability of GSP and GSP expressed as a percentage of total serum albumin (%GA) using a variance component approach and localize genomic regions (QTLs) that harbor genes likely to influence GSP and %GA trait variation in a large extended multigenerational pedigree from Jiri, Nepal (n=1,800). We also performed quantitative bivariate analyses to assess the relationship between GSP or %GA and several cardiometabolic traits. …”
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Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy by Gaetana Messina, Giovanni Natale, Alfonso Fiorelli, Maria Antonietta Puca, Fiorenzo Moscatelli, Vincenzo Monda, Marcellino Monda, Marina Di Domenico, Carminia Maria Della Corte, Gabriella Marsala, Giuseppe Vicario, Carmine Dalia, Paola Bassi, Beatrice Leonardi, Antonella De Maria, Antonietta Monda, Giovanni Messina, Antonietta Messina, Rita Polito

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Le français dans la géopolitique méditerranéenne by Raymond Renard

“…Il s’ensuit que le véritable enjeu n’est pas celui du français contre l’anglais, mais celui du « plurilinguisme contre l’uniformité ». …”
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Parents' perception of the promotion of physical activity as part of the Purzelbaum project in Swiss daycare centers by Bianca Celine Schmidli, Claudio R. Nigg

“…The Fisher-Freeman-Halton exact test (in SPSS) was used for analyses. Results Parents (n=353; mean age=37.93, SD=5.24; 86% completed Bachelor; 73% female; mean # of days children spent in daycare=2.39, SD=1.00; 84 Purzelbaum and 278 non-Purzelbaum daycare centers) completed the questionnaire. …”
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<i>‘Changing the Focus’</i>: Co-Design of a Novel Approach for Engaging People with Dementia in Physical Activity by Claudia Meyer, Den-Ching A. Lee, Michele Callisaya, Morag E. Taylor, Katherine Lawler, Pazit Levinger, Susan Hunter, Dawn C. Mackey, Elissa Burton, Natasha Brusco, Terry Haines, Christina L. Ekegren, Amelia Crabtree, Keith D. Hill

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Clinical Features and Changes in Insulin Requirements in People with Type 2 Diabetes Requiring Insulin When Hospitalised with SARS-CoV-2 Infection by Antonella Corcillo, Aaisha Saqib, Niruthika Sithamparanathan, Amina Khanam, Jamal Williams, Abhiti Gulati, Dulmini Kariyawasam, Janaka Karalliedde

“…We observed that of 113 people with T2DM, 35% (n = 39) needed insulin as a new treatment during their hospitalisation for SARS-CoV-2 infection. …”
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