Cx43 Inhibition Attenuates Sepsis-Induced Intestinal Injury via Downregulating ROS Transfer and the Activation of the JNK1/Sirt1/FoxO3a Signaling Pathway by Zhaowei Zou, Bin Liu, Lisi Zeng, Xianzi Yang, Renli Huang, Cheng Wu, Huijuan Zhu, Yi Gao, Dongdong Yuan, Jinlong Yu

“…Firstly, different methods, such as Cx43 inhibitors (18-α-GA and oleamide) or siRNA targeting Cx43 and N-acetyl cysteine (NAC) (a kind of ROS scavenger), were used to observe the effects of Cx43 channels mediating ROS transfer on intestinal injury. …”
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The bergen 4-day treatment for panic disorder: a longer-term follow-up by Thorstein Olsen Eide, Bjarne Hansen, Kay Morten Hjelle, Stian Solem, Michael G. Wheaton, Thröstur Björgvinsson, Gerd Kvale, Kristen Hagen

“…This study extends a previously published study by providing a long-term follow-up of the same cohort (n = 30), initially assessed at three months post-treatment. …”
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Evaluation of Juice Production Characteristics and Analysis of Characteristic Flavor Components of Phyllanthus emblica Fruit Varieties by Zifen ZHENG, Xiaowei CHEN, Bo ZOU, Yuanshan YU, Gengsheng XIAO, Lukai MA

“…Trans-2-decenoaldehyde, n-octyl aldehyde and nonylaldehyde were the main aroma components. …”
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PD‐1+CD8+ T Cell‐Mediated Hepatocyte Pyroptosis Promotes Progression of Murine Autoimmune Liver Disease by Jie Long, Si‐Yu Yang, Zhen‐Hua Bian, Hao‐Xian Zhu, Min Ma, Xiao‐Qing Wang, Liang Li, Weici Zhang, Ying Han, M. Eric Gershwin, Zhe‐Xiong Lian, Zhi‐Bin Zhao

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Efficacy and Safety of Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled by Amlodipine: A Phase III, Multicenter, Double‐Blind, Parallel‐Group, R... by Hongjie Chi, Xin Zhang, Shumei Ma, Gang Pan, Xiaojuan Lian, Yan Chen, Haotian Pei, Zichen Liu, Xiangmin Lin

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Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests by Aysha Mohamed Rafik Patel, Gina Gilpin, Anna Koniotes, Catherine Warren, Cian Xu, Paul W. Burgess, Dennis Chan

“…Cognitive performance was assessed using the ACE-III, with 20 participants also being tested on the digital Long COVID Assessment Battery (LCCAB) (N = 20). Results: The overall sample had a mean ACE-III score of 91/100 (SD 6) with 15.7% (16/102) scoring at or below the cut-off score considered to represent objective cognitive impairment. …”
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Efficiency metrics for ocean alkalinity enhancements under responsive and prescribed atmospheric <i>p</i>CO₂ conditions by M. D. Tyka

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Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japane... by Shintaro Yamaguchi, Junichiro Irie, Masanori Mitsuishi, Yuichi Uchino, Hideaki Nakaya, Ryo Takemura, Emi Inagaki, Shotaro Kosugi, Hideyuki Okano, Masato Yasui, Kazuo Tsubota, Kaori Hayashi, Jun Yoshino, Hiroshi Itoh

“…In participants with insulin oversecretion after oral glucose loading, NMN modestly attenuated postprandial hyperinsulinemia, a risk factor for coronary artery disease (n = 3). In conclusion, NMN overall safely and effectively boosted NAD+ biosynthesis in healthy, middle-aged Japanese men, showing its potential for alleviating postprandial hyperinsulinemia.…”
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Digital Quantitative Detection for Heterogeneous Protein and mRNA Expression Patterns in Circulating Tumor Cells by Hao Li, Jinze Li, Zhiqi Zhang, Qi Yang, Hong Du, Qiongzhu Dong, Zhen Guo, Jia Yao, Shuli Li, Dongshu Li, Nannan Pang, Chuanyu Li, Wei Zhang, Lianqun Zhou

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Investigating the effect of using a home safety training application by caregivers on accident risk management in the elderly by Mahdie Dehnavi, Najmeh Valizadeh zare, Seyd Reza Mazlom, Samira Mohajer, Tahereh Sadeghi, Mohammad Namazinia, Danial Baghie

“…Trial registration: This study was registered in the Iranian Registry of Clinical Trials (no. IRCT20210610051532N1) on 07/09/2021.…”
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Descarga mássica de lote impermeabilizado: análise de first flush, eficiências e estimativa de carga by Ademir Paceli Barbassa, Leonardo Kenji Maeda, Rodrigo Braga Moruzzi, Anai Floriano Vasconcelos

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ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation by Jiaxing Zhang, Jiaxing Zhang, Gang Wang, Jie Liu, Futian Tang, Song Wang, Yumin Li, Yumin Li

“…Moreover, ITGA4 was correlated with N stage, pathological stage, neural and vascular invasion, serum levels of Ki-67, immune cells, CRP and CA125.ConclusionITGA4 is a potential biomarker and therapeutic target to enhance cancer treatment and improve patient outcomes.…”
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Effects of Mn addition on wear and corrosion resistances of AlCoCrFeNi high-entropy alloy coating sprayed by HVOF by Dandan Zhang, Qiang Li, Chuntao Chang, Guan Zhang, Xu Ma, Rongze Sun

“…The dry sliding wear test demonstrates that the Mn0.5 coating demonstrates superior wear resistance with a significantly lower average friction coefficient of 0.433 and wear rate of 9.7 × 10−5 mm3·N−1·m−1 compared to both the Mn0 coating and 304 stainless steel. …”
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Functional and structural characterization of mouse Factor H-related B protein unveils a novel dimerization domain shared by FHR-B and FH by Adrián Martín-Ambrosio Doménech, Silvia González Sanz, Bárbara Márquez Tirado, Lucia Juana-López, Elena Goicoechea de Jorge, Santiago Rodríguez de Córdoba, Héctor Martín Merinero

“…Dimerization occurs through the N-terminal region (SCR1-3), which differs from mFH SCR5-7 by only four amino acids and also shares significant homology with human FHR-3 and human FH SCR5-7. …”
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Wedge‐Like Microstructure of Al2O3/i‐Ti3C2Tx Electrode with “Nano‐Pumping” Effect for Boosting Ion Diffusion and Electrochemical Defluoridation by Junce Wang, Jinfeng Chen, Ningning Liu, Jingjing Lei, Hong‐Wen Gao, Fei Yu, Fanghui Pan, Jie Ma

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Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers by Juanjuan Zhang, Li Zhou, Lili Cui, Zhenhua Liu, Jinfeng Wei, Wenyi Kang

“…Ethyl acetate fraction (CLEa) and n-butanol fraction (CLBu) exhibited antioxidant and α-glucosidase inhibitiory activity in vitro, and the corresponding active fractions, EaFr.3, EaFr.5 and BuFr.1, exhibited higher antioxidant and α-glucosidase inhibitiory activity than those of other fractions. …”
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Can Large Language Models Aid Caregivers of Pediatric Cancer Patients in Information Seeking? A Cross‐Sectional Investigation by Emre Sezgin, Daniel I. Jackson, A. Baki Kocaballi, Mindy Bibart, Sue Zupanec, Wendy Landier, Anthony Audino, Mark Ranalli, Micah Skeens

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Viral Transcript and Tumor Immune Microenvironment-Based Transcriptomic Profiling of HPV-Associated Head and Neck Squamous Cell Carcinoma Identifies Subtypes Associated with Progno... by Anastasiia Nikitina, Daria Kiriy, Andrey Tyshevich, Dmitry Tychinin, Zoya Antysheva, Anastasya Sobol, Vladimir Kushnarev, Nara Shin, Jessica H. Brown, James Lewis, Krystle A. Lang Kuhs, Robert Ferris, Lori Wirth, Nikita Kotlov, Daniel L. Faden

“…In order to understand specific factors associated with prognosis, we used the unsupervised clustering of an HPV-positive HNSCC cohort from The Cancer Genome Atlas (TCGA) (n = 53) based on HPV transcript expression, and identified four HPV-related subtypes (E2/E5, E6/E7, E1/E4 and L1/L2). …”
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Exploration of pulse wave analysis under reactive hyperemia and close to an arteriovenous fistula: a comparative analysis by Veit Busch, Sandra Müller, Joachim Streis, Timm H. Westhoff, Thomas Felderhoff, Felix S. Seibert, Stefan Reuter, Niklas Mueller

“…Results A total of 108 subjects were evaluated (23 healthy and 85 with fistula in two distinct collectives n = 39/45, measurements under reactive hyperemia in 62 individuals). …”
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Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation by Inho Kang, John Bilbily, Choong Yeon Kim, Chuanqian Shi, Manish K. Madasu, Eun Young Jeong, Kyle E. Parker, Do A Kwon, Bum‐Joon Jung, Jae‐Soon Yang, Juhyun Lee, Noah D.L. Kabbaj, Wonhee Lee, Jun‐Bo Yoon, Ream Al‐Hasani, Jianliang Xiao, Jordan G. McCall, Jae‐Woong Jeong

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