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  1. 46121

    How drinking motives mediate associations between sexual orientation and indicators of alcohol use – a study among young Swiss men by Matthias Wicki, Matthias Wicki, Simon Marmet, Joseph Studer, Joseph Studer, Kim Bloomfield, Kim Bloomfield, Kim Bloomfield, Gerhard Gmel, Gerhard Gmel, Gerhard Gmel, Gerhard Gmel

    Published 2025-01-01
    “…., enhancement, social, coping and conformity motives).MethodA non-self-selective sample of non-abstinent, young Swiss men (N = 5,139; mean age = 25.4, SD = 1.25) completed a self-reporting questionnaire on sexual orientation (on a five-point attraction scale: heterosexual, mostly-heterosexual, bisexual, mostly-homosexual, homosexual), drinking motives, alcohol use indicators (e.g., heavy episodic drinking, Alcohol Use Disorders Identification Test-Consumption [AUDIT-C]), and AUD symptoms. …”
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  2. 46122

    Intraoperative haemodynamic optimisation using the Hypotension Prediction Index and its impact on tissular perfusion: a protocol for a randomised controlled trial by Javier Ripollés-Melchor, Ane Abad-motos, Juan Victor Lorente, Ignacio Jimenez, Alejandra Becerra, Wilbert Wesselink, Francesca Reguant, Irene Mojarro, Maria de los Angeles Fuentes, Elizabeth Agudelo, Francisco Herrero-Machancoses, Paula Callejo, Joan Bosch, Manuel Ignacio Monge

    Published 2022-06-01
    “…This study aims to determine whether a treatment protocol based on the prevention of arterial hypotension using the HPI algorithm reduces the duration and severity of intraoperative hypotension compared with the recommended goal-directed fluid therapy strategy and may improve tissue oxygenation and organ perfusion.Methods and analysis We will conduct a multicentre, randomised, controlled trial (N=80) in high-risk surgical patients scheduled for elective major abdominal surgery. …”
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  3. 46123

    Investigating dynamic brain functional redundancy as a mechanism of cognitive reserve by Julia Schwarz, Franziska Zistler, Adriana Usheva, Anika Fix, Sebastian Zinn, Juliana Zimmermann, Franziska Knolle, Franziska Knolle, Gerhard Schneider, Rachel Nuttall

    Published 2025-02-01
    “…In this study we aimed to investigate whether BFR modulates the association between age-related brain changes and cognitive performance across a broad range of cognitive domains.MethodsAn open-access neuroimaging and behavioral dataset (n = 301 healthy participants, 18–89 years) was analyzed. …”
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  4. 46124

    The Role of Neuroglial Crosstalk and Synaptic Plasticity-Mediated Central Sensitization in Acupuncture Analgesia by Zhongxi Lyu, Yongming Guo, Yinan Gong, Wen Fan, Baomin Dou, Ningcen Li, Shenjun Wang, Yuan Xu, Yangyang Liu, Bo Chen, Yi Guo, Zhifang Xu, Xiaowei Lin

    Published 2021-01-01
    “…., the p38, extracellular signal-regulated kinases, and c-Jun-N-terminal kinase pathways), which contribute to the activation of nociceptive neurons. …”
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  5. 46125

    Hyaluronic Acid-Based Hybrid Nanoparticles as Promising Carriers for the Intranasal Administration of Dimethyl Fumarate by Serri C, Piccioni M, Guarino V, Santonicola P, Cruz-Maya I, Crispi S, Di Cagno MP, Ferraro L, Dalpiaz A, Botti G, Giunchedi P, Rassu G, Gavini E

    Published 2025-01-01
    “…The cytotoxicity and cellular uptake studies were performed using RPMI 2650 and SK-N-BE2 cell lines. DMF nose-to–brain delivery was evaluated by intranasally administering DMF-loaded LPNs to rats.Results: LPNs with average sizes of 120– 250 nm and a negative zeta potential − 17.3 to − 43 mV were obtained, primarily influenced by the presence of HA. …”
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  6. 46126

    Characterization of Bozitinib as a potential therapeutic agent for MET-amplified gastric cancer by Hang Lin, Lingzhi Qu, Hudie Wei, Ming Guo, Xiaojuan Chen, Qianmeng Lin, Huajun Zhang, Shuyan Dai, Yongheng Chen

    Published 2025-01-01
    “…In addition, bozitinib efficiently inhibits c-Met resistance-conferring mutations G1163R and Y1230H, although its potency is significantly decreased against the D1228N and Y1230C mutations. Overall, our study reveals the molecular mechanism of bozitinib against c-Met, highlights its ability to overcome acquired resistance mutations, and provides valuable insights into further design and improvement of selective c-Met inhibitors.…”
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  7. 46127
  8. 46128

    Engagement and Follower Growth: Social Media Strategies of Swiss Athletes at the Paris Olympics by Larssyn Staley, Florian Droux

    Published 2025-01-01
    “…References Bredikhina, N., Gupta, K., & Kunkel, T. (2023). Superboosting the athlete social media brand: Events as an opportunity for follower growth. …”
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  9. 46129
  10. 46130
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  12. 46132
  13. 46133

    Comparison of growth models to describe growth from birth to 6 years in a Beninese cohort of children with repeated measurements by Achille Massougbodji, Michel Cot, Shukrullah Ahmadi, Florence Bodeau-Livinec, Roméo Zoumenou, André Garcia, David Courtin, Jules Alao, Nadine Fievet, Jérémie Botton

    Published 2020-09-01
    “…Objective To select a growth model that best describes individual growth trajectories of children and to present some growth characteristics of this population.Settings Participants were selected from a prospective cohort conducted in three health centres (Allada, Sekou and Attogon) in a semirural region of Benin, sub-Saharan Africa.Participants Children aged 0 to 6 years were recruited in a cohort study with at least two valid height and weight measurements included (n=961).Primary and secondary outcome measures This study compared the goodness-of-fit of three structural growth models (Jenss-Bayley, Reed and a newly adapted version of the Gompertz growth model) on longitudinal weight and height growth data of boys and girls. …”
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  14. 46134
  15. 46135
  16. 46136

    Treatment patterns and clinical profile in progressive pulmonary fibrosis: a Japanese cross-sectional survey by Hidekata Yasuoka, Yuko Waseda, Yuko Kaneko, Masateru Okazaki, Ryoko Iwasaki, Shoko Nagata, Mark Small, Haruyuki Ishii

    Published 2025-01-01
    “…As reported by patients themselves (n = 53), 49.1% never and 37.7% rarely missed a dose.ConclusionThis analysis of real-world data from Japan provides insights into the clinical profile of patients with IPF and PPF in Japan, and highlights differences between physicians and patients in perception of symptom severity and attitudes to treatment.…”
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  17. 46137

    Protective Effect of Rosmarinic Acid on Endotoxin-Induced Neuronal Damage Through Modulating GRP78/PERK/MANF Pathway by Li Q, Zheng JW, Wang ZY, Liao SP, Zhu L, Wang X, Wan LH

    Published 2025-01-01
    “…Western blotting and Immunohistochemistry (IHC) were performed to determine NeuN, GRP78, PERK, ATF6, IRE1α, and MANF expression levels. …”
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  18. 46138

    Sport innovation structure landscape in Switzerland and abroad by Christelle Ganné-Chedeville, Solange Emmenegger, Hippolyt Kempf, Cornel Gübeli

    Published 2025-01-01
    “…., Fischer, M., Arboit, N., Villardita, L., Sollberger, P., & Körsgen, A. (2022). …”
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  19. 46139

    Storage and permeation space development characteristics and water production capacity evaluation of deep coal reservoirs in Linxing-Shenfu area of Ordos Basin by Jinwei WANG, Hao XU, Yinan LIU, Bing ZHANG, Yanyong XU, Ding LIU, Peng ZONG, Yajuan WANG, Xuejing SONG

    Published 2025-01-01
    “…This study conducted multi-scale characterizations of coal samples from the 8#+9# coal seams in the Linxing-Shenfu area using high-pressure mercury intrusion porosimetry, low-temperature CO2 adsorption, low-temperature N2 adsorption, and CT scanning experiments. These methods revealed the development characteristics of the storage and permeability space in the study area. …”
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  20. 46140