Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results by Sutema IAMP, Latarissa IR, Widowati IGAR, Sartika CR, Ciptasari NWE, Lestari K

“…Ida Ayu Manik Partha Sutema,1,2 Irma Rahayu Latarissa,1,3 I Gusti Ayu Rai Widowati,2 Cynthia Retna Sartika,1,4 Ni Wayan Eka Ciptasari,5 Keri Lestari1,3,6 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Clinical Pharmacy Study Program, Faculty of Health Sciences, Bali International University, Denpasar, Indonesia; 3Medication Therapy Adherence Clinic (MTAC), Universitas Padjadjaran, Sumedang, Indonesia; 4PT Prodia StemCell Indonesia, Central Jakarta, Jakarta, Indonesia; 5Ngoerah Sun Wellness and Aesthetic Center, Prof. Dr. I.G.N.G. Ngoerah Central General Hospital, Denpasar, Indonesia; 6Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence: Keri Lestari, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia, Email lestarikd@unpad.ac.idAbstract: Acne vulgaris is a prevalent dermatological condition characterized by comedones, papules, and pustules, with significant physical and psychological implications. …”
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Contradições entre Narrativas e Práticas dos Consumidores de Dispositivos Eletrônicos para Fumar by Cristina de Abreu Perez, Maribel Carvalho Suarez, Thaysa Nascimento, Luiza Novais Tavares, Karina Prince

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Early experience of Sacubitril–Valsartan in heart failure with reduced ejection fraction in real‐world clinical setting by Charlotte Nordberg Backelin, Michael Fu, Charlotta Ljungman

“…Patients were adjudicated to be eligible based on European Society of Cardiology (ESC) criteria for angiotensin receptor neprilysin inhibitor (ARNI) with the exception of N‐terminal (NT)‐proBNP levels. Patients who received <50% of target dose angiotensin‐converting enzyme/angiotensin receptor blocker and otherwise fulfilled ESC criteria were adjudicated to be potentially eligible. …”
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Spectroscopic Confirmation of a Massive Protocluster with Two Substructures at z ≃ 3.1 by Michael J. Nicandro Rosenthal, Amy J. Barger, Lennox L. Cowie, Logan H. Jones, Stephen J. McKay, Anthony J. Taylor

“…We present the results of a Keck and Northern Extended Millimeter Array spectroscopic survey of 507 galaxies, where we confirm the presence of two massive overdensities at z = 3.090−3.110 and z = 3.133−3.155 in the neighborhood of the GOODS-N, each with over a dozen spectroscopically confirmed members. …”
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Clinical Efficacy of Curcumin and Vitamin E on Inflammatory-Oxidative Stress Biomarkers and Primary Symptoms of Menopause in Healthy Postmenopausal Women: A Triple-Blind Randomized... by Azizeh Farshbaf-Khalili, Alireza Ostadrahimi, Mojgan Mirghafourvand, Khatereh Ataei-Almanghadim, Sara Dousti, Amir Mehdi Iranshahi

“…The trial was registered at the Iranian Registry of Clinical Trials (https://irct.ir/IRCT20131009014957N6).…”
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不同剂量苯那普利对自发性高血压大鼠肾小球硬化的影响

“…【目的】 观察超大剂量血管紧张素转化酶抑制剂干预能否进一步抑制肾小球硬化65377;【方法】 30只8周龄雄性自发性高血压大鼠随机分为模型对照组(M组),大剂量(10 mg·kg-1·d-1)苯那普利治疗组(LT组),超大剂量(50 mg·kg-1·d-1)苯那普利治疗组(HT组),以10只Wistar-Kyoto大鼠(Wistar-Kyoto rats,WKY)为正常对照组(N组)65377;检测各组大鼠的血压65380;血清肌酐及24 h尿蛋白;RT-PCR和免疫组织化学方法分别检测肾组织转化生长因子-β1(transforming growth factor,TGF-β1)和纤溶酶原激活物抑制因子(Plasminogen Activator Inhibitor,PAI-1)的mRNA和蛋白表达;肾组织石蜡切片评估肾小球胶原沉积程度,采用MASSON染色65377; 【结果】 1)TGF-β1和PAI-1的mRNA和蛋白表达:LT组和HT组的TGF-β1和PAI-1 的mRNA和蛋白表达被抑制(P < 0.01);两治疗组间无统计学差异(P > 0.05)65377;2)肾小球胶原沉积:LT组和HT组的胶原面积/肾小球面积比值均明显减低(0.17 ± 0.15, 0.18 ± 0.11 vs 0.30 ± 0.28; P = 0.001);两治疗组间无统计学差异(0.17 ± 0.15 vs 0.18 ± 0.11; P=0.404)65377;【结论】 大剂量与超大剂量血管紧张素转化酶抑制剂均能降低血压,减少蛋白尿,抑制肾组织TGF-β1和PAI-1的mRNA和蛋白表达,延缓肾小球硬化;但超大剂量血管紧张素转化酶抑制剂不能进一步的抑制肾小球硬化65377;…”
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Impact of Different Serum Potassium Levels on Postresuscitation Heart Function and Hemodynamics in Patients with Nontraumatic Out-of-Hospital Cardiac Arrest by Yan-Ren Lin, Yuan-Jhen Syue, Tsung-Han Lee, Chu-Chung Chou, Chin-Fu Chang, Chao-Jui Li

“…Results. Most patients (59.9%, n = 287) had previously presented with high levels of potassium. …”
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Enrichment of Cancer‐Associated Fibroblasts, Macrophages, and Up‐Regulated TNF‐α Signaling in the Tumor Microenvironment of CMS4 Colorectal Peritoneal Metastasis by Eirik Høye, Chakravarthi Kanduri, Annette Torgunrud, Susanne Lorenz, Bjørn Edwin, Stein G. Larsen, Åsmund A. Fretland, Vegar J. Dagenborg, Kjersti Flatmark, Christin Lund‐Andersen

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A Retrospective Study to Investigate the Relationship Between Body Mass Index and Hemodynamic Characteristics in Hypertensive Patients by Wenqi Xiao, Ping Han, Liping Song, Jingwen Yang, Lin Zhou, Xiangning Deng, Zheng J. Ma, Yukun Lang, Hai Zhao, Yuzhuo Zhao, Hui Chen, Wenjing Zhang, Huixian Huang, Ningling Sun

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AI Interventions to Alleviate Healthcare Shortages and Enhance Work Conditions in Critical Care: Qualitative Analysis by Nadine Bienefeld, Emanuela Keller, Gudela Grote

“…The qualitative analysis is underpinned by extensive workplace observation in 6 ICUs (approximately 559 nurses and physicians), structured interviews with work unit leaders (n=12), and a comparative analysis of data science experts’ and clinicians’ evaluation of the optimal levels of human-AI teaming. …”
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Assessment of changes in soil contact stress depending on tractor tire parameters by Savelii Kukharets, Andrii Zabrodskyi, Bohdan Sheludchenko, Algirdas Jasinskas, Rolandas Domeika, Egidijus Šarauskis

“…The tractor with a working tire width of 0.92 m and an axle load of 119.5 kN generate contact stresses on the field surface of up to 150 kPa, which is a permissible load for soil structure safety. …”
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Renaissance Man, Man of his Times: Norman Mailer’s "The White Negro" and Literary Manhood in 1950s America by Matthew Kriz

“…Il propose que l’essai soit lu comme une condamnation de la définition de la masculinité dans les années 50, la solution donnée par Mailer à ce problème étant la libération sexuelle, ce qui équivaut à un repositionnement de la masculinité américaine, qui n’est pas vue uniquement comme définie par une classe moyenne blanche hétérosexuelle.…”
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Early Devonian Slab Melting of the Proto-Tethys Ocean: Insights from Adakitic Granitoids in the Jiayuguan Area, Hexi Corridor (NW China) by Qigui Mao, Wenjiao Xiao, Rui Li, Songjian Ao, Dongfang Song, Miao Sang, Hao Wang, Zhou Tan

“…The granitoids exhibit typical adakitic geochemical signatures with high SiO2 (>56%), Na, Al, and Sr contents, depleted in Yb and Y, and high Sr/Y (82–277) and (La/Yb)N (7.65–15.16) values. Additionally, their high Mg# (62–68) and εHf(t) (+6.5–+11.9) values indicate partial melting of slab genesis. …”
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Ebbs and Flows of Marine Biodiversity: Navigating Spatiotemporal Patterns of Environmental DNA in a Coastal Tidal Ecosystem by Michelle Scriver, Ulla vonAmmon, Xavier Pochon, Martin Zirngibl, Francois Audrezet, Kaeden Leonard, Kylie Pedersen, Nick Bamford, Ngairo Tahere, Jo‐Ann L. Stanton, Neil J. Gemmell, Anastasija Zaiko

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Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Eff... by Anastasia Latanova, Stefan Petkov, Yulia Kuzmenko, Athina Kilpeläinen, Alexander Ivanov, Olga Smirnova, Olga Krotova, Sergey Korolev, Jorma Hinkula, Vadim Karpov, Maria Isaguliants, Elizaveta Starodubova

“…Inactivated multidrug-resistant RT (RT1.14opt-in) was N-terminally fused to the signal providing secretion of NS1 protein of TBEV (Ld) generating optimized inactivated Ld-carrying enzyme RT1.14oil. …”
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Tradução e adaptação transcultural do questionário “Barriers to Being Active Quiz (BBAQ)’’ para a língua portuguesa brasileira by Bruno Oliveira Amorim Sampaio, Thiago Ferreira de Sousa, Jeffer Eidi Sasaki, Emerson Sebastião, Camila Bosquiero Papini, Alynne Christian Ribeiro Andaki

“…Foram realizadas as seguintes etapas: (1) tradução do questionário original em inglês para o português; (2) resolução de divergências entre a versão 1 e a versão 2 e criação da versão síntese; (3) retrotradução para o inglês; (4) revisão e avaliação do comitê de especialistas, construção da versão pré-teste; e (5) pré-teste com a avaliação da compreensão por uma amostra (n = 30) da população-alvo. A versão final do BBAQ possui 21 questões. …”
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In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux by Yulin Lv, Benli Song, Guang Yang, Yuting Wang, Zeyu Wu, Minggui Si, Zongzheng Yang, Huilin Chen, Chen Liu, Min Li, Yinshi Zhang, Zengying Qiao, Lu Wang, Wanhai Xu

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Dynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors by Saima Rashid, Abdul Bariq, Ilyas Ali, Sobia Sultana, Ayesha Siddiqa, Sayed K. Elagan

“…We remark that in various time scale domains $$\mathbb {N}_{\ell }$$ , the investigated discrete formulations will be $$\rho ^{2}$$ -nonincreasing or $$\rho ^{2}$$ -nondecreasing by examining $$\rho$$ -monotonicity formulations and the basic properties of the suggested operator. …”
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Ionospheric Response to the 24–27 February 2023 Solar Flare and Geomagnetic Storms Over the European Region Using a Machine Learning–Based Tomographic Technique by Ting Li, Dunyong Zheng, Changyong He, Fei Ye, Pengfei Yuan, Yibin Yao, Mengguang Liao, Jian Xie

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Impact of ChatGPT usage on nursing students education: A cross-sectional study by Alberto Gonzalez-Garcia, David Bermejo-Martinez, Ana Isabel Lopez-Alonso, Bibiana Trevisson-Redondo, Cristian Martín-Vázquez, Silvia Perez-Gonzalez

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