Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages by Hiroki Yamazaki, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Yusuke Nakatsu, Takako Kikuchi, Sunao Kaneko, Hirotoshi Tanaka, Tomoichiro Asano

“…In this study, using adipocytes and macrophages, we focused on the in vitro effects of SHBG on inflammation as well as lipid metabolism. Incubation with 20 nM SHBG markedly suppressed lipopolysaccharide- (LPS-) induced inflammatory cytokines, such as MCP-1, TNFα, and IL-6 in adipocytes and macrophages, along with phosphorylations of JNK and ERK. …”
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Komparasi Pembelajaran IPA Terpadu Tipe Connected dan Webbed melalui LSLC terhadap Hasil Belajar Kognitif Siswa di SMP Negeri 11 Semarang by Ayu Fitriani, Eko Retno Mulyaningrum, Rivanna Cittraning Rachmawati

“…Komparasi hasil belajar kognitif siswa pada materi sistem pernapasan manusia yang memiliki presentase dengan kriteria sangat baik adalah pembelajaran IPA terpadu tipe webbed dan pembelajaran IPA terpadu tipe connected memiliki presentase dengan kriteria baik melalui Lesson Study for Learning Community sehingga pembelajaran IPA terpadu yang efektif untuk digunakan pada materi sistem pernapasan manusia melalui lesson study for learning community di SMP N 11 Semarang adalah tipe webbed.…”
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Moxibustion for Herpes Zoster and Postherpetic Neuralgia: A Meta-Analysis by Yuanen Huang, Jingping Wu, Hongbin Cheng, Yanling Liu

“…From a total of 1957 identified studies, 31 were included in analysis (N = 2334 cases). 31 RCTs contained the experimental sample of 1185 cases and the control sample of 1149 cases reported efficiency of different moxibustions in the treatment of herpes zoster, statistical heterogeneity inspection without heterogeneity. …”
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A Neural Circuit For Bergamot Essential Oil‐Induced Anxiolytic Effects by Meng‐Yu Zhu, Wan‐Ying Dong, Jin‐Rong Guo, Ji‐Ye Huang, Ping‐Kai Cheng, Yumeng Yang, An Liu, Xin‐Lu Yang, Xia Zhu, Zhi Zhang, Yuanyin Wang, Wenjuan Tao

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Consumer Products Nerve Injuries Among Patients Products Presenting to United States Emergency Departments Between 2012 and 2021: A Nationwide Cohort by Ganga A, Mukhdomi T, Kim EJ, Ly E, Patel Y, Dankievitch KN, Kendall MC

“…Arjun Ganga,1 Taif Mukhdomi,2 Eric J Kim,1 Eric Ly,3 Yash Patel,3 Korinne N Dankievitch,3 Mark C Kendall3 1Warren Alpert School of Medicine, Brown University, Providence, RI, 02903, USA; 2Department of Pain, Pain Zero, New Albany, OH, 43054, USA; 3Department of Anesthesiology, Warren Alpert School of Medicine, Brown University, Providence, RI, 02903, USACorrespondence: Mark C Kendall, Department of Anesthesiology, Warren Alpert School of Medicine, Brown University, 593 Eddy Street, Davol #129, Providence, Rhode Island, 02903, USA, Tel +414-444-5172, Email mark.kendall@lifespan.orgIntroduction: Nerve injuries and resultant pain are common causes of emergency department (ED) visits in the United States. …”
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Heart Failure in Atrial Fibrillation Subtypes in Women and Men in the Tromsø Study by Hilde Espnes, MD, Tom Wilsgaard, PhD, Jocasta Ball, PhD, Maja-Lisa Løchen, MD, PhD, Inger Njølstad, MD, PhD, Renate B. Schnabel, MD, MSc, Eva Gerdts, MD, PhD, Ekaterina Sharashova, MD, PhD

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Phylogeography and genetic diversity of Ulmus elongata (Ulmaceae), a Tertiary relict tree with extremely small populations (PSESP) by Yakun Wang, Xiankun Wang, Junyuan Wu, Jun Yang, Yanpei Liu, Peng Guo, Fude Shang, Nan Lin

“…A notable phylogeographic structure was identified in U. elongata, comprising eight distinct haplogroups (N ST = 0.917, G ST = 0.876, p < 0.05), which was attributed to the global cooling in the East Asia and Quaternary climate oscillations. …”
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基于生物信息学途径评估 UBE2 家族及 UBE2T 基因在肺腺癌中的表达及临床意义 by 杨豪帅, 赖慧娜, 饶怡茹, 林晓平

“…【方法】利用linkedomics平台进行UBE2C、UBE2M、UBE2S、UBE2T、UBE2V2 mRNA表达水平与肺腺癌临床特征之间的关系分析，对总生存时间（OS）（Cox回归检验）、总分期（Kruskal-WallisH检验）、T分期（Kruskal-WallisH检验）、N分期（Kruskal-WallisH检验）及M分期（Wilcox秩和检验）进行差异比较。运用肿瘤基因组图谱（TCGA）数据库获取UBE2T基因在肺腺癌组织和癌旁组织中的表达信息，将结果进行两独立样本t检验。…”
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Visual Outcomes and Quality of Vision After Bilateral Implantation of a Hydrophobic Acrylic Trifocal Intraocular Lens by Newsom TH, Szabo B, Unsell K, Newsom C, Newsom BA, Hall B

“…T Hunter Newsom,1 Brian Szabo,1 Kayla Unsell,1 Chase Newsom,1 Brooke Ayers Newsom,1 Brad Hall2 1Newsom Eye, Sebring, FL, USA; 2Sengi, Penniac, NB, CanadaCorrespondence: T Hunter Newsom, Newsom Eye, 4211 US Hwy 27 N, Sebring, FL, 33870, USA, Tel +1-813-908-2020, Email hunter@newsomeye.netPurpose: To evaluate visual outcomes and quality of vision following bilateral implantation of a hydrophobic acrylic intraocular lens (IOL) in eyes targeted for emmetropia.Methods: This was a prospective, single arm study. …”
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Melatonin Alleviates LPS-Induced Pyroptotic Cell Death in Human Stem Cell-Derived Cardiomyocytes by Activating Autophagy by Ya Qiu, Yan Ma, Min Jiang, Sulei Li, Jibin Zhang, Haixu Chen, Mengqi Xu, Shan Gao, Lei Tian, Bo Tao, Yabin Wang, Dong Han, Feng Cao

“…Specifically, Mel profoundly alleviated LPS-induced cell pyroptosis, as evidenced by decreased propidium iodide (PI) and active caspase-1 double-positive cell rates; suppressed the expression of NLRP3, cleaved caspase-1 (activated form of caspase-1), and GSDMD-NT (functional N-terminal fragment of GSDMD) expression; and inhibited the production of the cleaved IL-1β and cleaved IL-18 cytokines. …”
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间充质干细胞通过诱导M2型巨噬细胞治疗急性肺损伤 by 孙瑶, 吕海金, 易小猛, 郭俊, 易慧敏

“…③30只balb/c雄性小鼠随机均分成control组、ALI组、ALI+MSC组（均n=10），LPS滴鼻法建立小鼠急性肺损伤（ALI）模型，用MSC治疗48h后，肺组织苏木素-伊红（HE）染色进行损伤评估；提取肺泡灌洗液（BALF），其中细胞用流式和qPCR检测M2型巨噬细胞markerCD206、IL-10和Arg1的表达；ELISA检测BALF上清M1型巨噬细胞marker TNF-α。…”
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An Exceptionally Powerful, Radiatively Driven Ultrafast Outflow in the Rapidly Accreting AGN RE J1034+396 by Chloe S. Taylor, Daniel R. Wilkins, Steven W. Allen

“…Modelling of these data confirms the presence of the UFO and constrains its equivalent hydrogen column density, log N _H /(atom cm ^−2 ) = ${21.7}_{-0.2}^{+0.1}$ . …”
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Characteristics and Source-specific Health Risks of Ambient PM2.5-bound PAHs in an Urban City of Northern Taiwan by Yu-Chieh Ting, Chun-Hung Ku, Yu-Xuan Zou, Kai-Hsien Chi, Jhy-Charm Soo, Chin-Yu Hsu, Yu-Cheng Chen

“…Studies on PM2.5-bound PAHs and their source-specific human health risks still remain scarce. Daily PM2.5 samples (n = 119) were collected every three days from 2016 to 2017 in Taipei city, Taiwan. …”
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Computational and experimental exploration of morpholine pendent 2-hydrazineyl thiazole: Insights from DFT, ADME profiling, antifungal efficacy and molecular docking analyses by Vishnu A. Adole, I.Antony Danish, J.Jebasingh Kores, J.Winfred Jebaraj, S. Janani, Suresh K. Ghotekar, Rakesh D. Amrutkar

“…Significant interactions between the donor and acceptor, namely involving LP(3)N25 → σ*C24-C26, were confirmed by second-order perturbation energies, yielding a stabilization energy of 12.54 kcal/mol. …”
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Factors that influence the adoption of a school-based eHealth alcohol prevention program among Spanish personnel: a mixed methods study by Ester Alejandra Rosado-Pulido, Pablo Fernández-León, Marta Lima-Serrano, Hein de Vries

“…Third, the new questionnaire was administered to Spanish school personnel (N = 100), including the school management team, school counselors, and teachers. …”
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On the Magnetosphere‐Ionosphere Coupling During the May 2021 Geomagnetic Storm by M. Piersanti, D. Del Moro, A. Parmentier, M. Martucci, F. Palma, A. Sotgiu, C. Plainaki, G. D’Angelo, F. Berrilli, D. Recchiuti, E. Papini, L. Giovannelli, G. Napoletano, R. Iuppa, P. Diego, A. Cicone, M. Mergé, C. De Donato, C. De Santis, R. Sparvoli, P. Ubertini, R. Battiston, P. Picozza

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Co-Hydrothermal Carbonization of Goose Feather and Pine Sawdust: A Promising Strategy for Disposal of Sports Waste and the Robust Improvement of the Supercapacitor Characteristics... by Tingyu Ma, Jieni Wang, Xiaobo Han, Chuanbing Zhang, Yahui Xu, Leichang Cao, Shuguang Zhao, Jinglai Zhang, Shicheng Zhang

“…Comprehensive characterization demonstrated that the prepared M-3-25 (Biochar derived from mixed feedstocks (25 mg/g Cu in pine sawdust) at 700 °C with activator ratios of 3) possesses a high specific surface area 2501.08 m² g⁻¹ and abundant heteroatomic (N, O, and Cu), exhibiting an outstanding physicochemical structure and ultrahigh electrochemical performance. …”
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Halloysite nanotubes as delivery mechanism for feather protein-based multi-surfactant systems in crude oil dispersion application by Yaw Kwakye Adofo, Emmanuel Nyankson, Benjamin Agyei-Tuffour, Selassie Gbogbo, Christian Amoako, Joseph Arko Morgan, Gloria Pokuaa Manu, Grace Karikari Arkorful

“…For 24 wt% surfactants concentrations loaded HNTs; 100 wt%CFP-HNTs, 60 wt%CFP- 40 wt%L-HNTs, 20 wt%CFP- 80 wt%T-HNTs, 50 wt%CFP- 25 wt%T-25 wt%L-HNTs and 25 wt %CFP- 25 wt%T-50 wt%D-HNTs showed good interfacial tension lowering abilities by recording 6.39, 2.82, 2.43, 1.68, and 1.55 mN/m at 60s respectively. The CFP-based surfactant-HNTs dispersants formed very stable o/w emulsions against droplet coalescence and showed an increase in interfacial viscosity which contributed to the stability of their respective o/w emulsions. …”
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Comparison of different severe obesity definitions in predicting future cardiometabolic risk in a longitudinal cohort of children by Gilles Paradis, Melanie Henderson, Lisa Kakinami, Angelo Tremblay, Anna Smyrnova

“…Whether SO definitions differentially predict cardiometabolic disease risk is critical for proper clinical care and management but is unknown.Design Prospective cohort studySetting SO definitions were applied at baseline (2005–2008, Mage=9.6 years, n=548), and outcomes (fasting lipids, glucose, homoeostatic model assessment (HOMA-IR) and blood pressure) were assessed at first follow-up (F1: 2008–2011, Mage=11.6 years) and second follow-up (2015–2017, Mage=16.8 years) of the Quebec Adipose and Lifestyle Investigation in Youth cohort in Montreal, Quebec.Participants Respondents were youth who had at least one biological parent with obesity.Primary outcome measures Unfavourable cardiometabolic levels of fasting blood glucose (≥6.1 mmol/L), insulin resistance (HOMA-IR index ≥2.0), high-density lipoprotein &lt;1.03 mmol/L, low-density lipoprotein ≥2.6 mmol/L and triglycerides &gt;1.24 mmol/L. …”
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An exploration of desired abstinent and non-abstinent recovery outcomes among people who use methamphetamine by Alex Elswick, Amanda Fallin-Bennett, Karen L. Roper, Evan Batty, Christopher J. McLouth, William Stoops, Hilary L. Surratt, Carrie B. Oser

“…This study sought to expand the definition of recovery to include non-abstinent pathways by exploring non-abstinence-based outcomes desired by people who use methamphetamine (PWUM). Methods Participants (n = 100) were recruited from existing National Institute on Drug Abuse (NIDA) projects including a treatment-seeking sample of people recently released from prison (all of whom endorsed recent methamphetamine use) and a sample of people using syringe service programs. …”
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