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44761
Innovator ranibizumab ComparEd to Biosimilar ranibizumab in combination with Expansile gas in submaculaR HemorrhaGe: the ICEBERG study
Published 2025-01-01“…Methods Treatment naïve neovascular age related macular degeneration (n-AMD) patients with SMH were retrospectively analyzed. …”
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44762
Diagnostic and Management Pathways for Pulmonary Carcinoid Tumours in the United Kingdom: Results from the National Lung Neuroendocrine Tumour Pathway Project
Published 2020-01-01“…Adjuvant therapy is considered for resected TC/AC by <5% of respondents for patients with stage N0 M0 AC or TC, up to 48% of respondents for patients with AC with R1 disease. …”
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Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle
Published 2025-02-01“…In cancer models that are genetically independent of CDK2, pharmacological inhibitors suppress cell proliferation by inducing 4N cell cycle arrest and increasing the expressions of phospho-CDK1 (Y15) and cyclin B1. …”
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44767
Disrupted Regional Spontaneous Neural Activity in Mild Cognitive Impairment Patients with Depressive Symptoms: A Resting-State fMRI Study
Published 2019-01-01“…We obtained rsfMRI data in 16 MCI patients with depressive symptoms and 18 nondepressed MCI patients (nD-MCI) using a 3 T scanner. Statistical analyses were performed to determine the regions in which ReHo differed between the two groups in specific frequency bands, slow-4 (0.027–0.073 Hz) and slow-5 (0.010–0.027 Hz), and typical bands (0.01–0.08 Hz). …”
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44768
Facile construction of polyoxometalate-modified polyaryletherketone-based hybrid membranes with enhanced proton conductivity
Published 2025-03-01“…Herein, the Keggin-type POM H3PW12O40·nH2O (PW12) was introduced into sulfonated polyaryletherketone (SPAEK) with closely packed and flexible side chains to construct hybrid membranes (SPAEK-PW12-x%, x = 5, 10, 13, 15). …”
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44769
Electronic and photophysical properties of copper (II) Complexes: Insights into solvatochromic Effects, Photoreduction, and fluorescence behavior
Published 2025-01-01“…UV–Vis absorption spectroscopy unveils significant insights, revealing absorption peaks attributed to ligand–metal charge transfer transitions (LMCT) and π → π* transitions of C = N bonds. The solvent’s polarity dictates the absorption peak positions, indicating a pronounced solvatochromic effect. …”
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44770
Pre-injury frailty and clinical care trajectory of older adults with trauma injuries: A retrospective cohort analysis of A large level I US trauma center.
Published 2025-01-01“…We limited the data to adults 65 years and older, who had trauma injuries and frailty screening at ED presentation (N = 2,862). The predictor variable was frailty status, measured as either robust (score 0), pre-frail (score 1-2), or frail (score 3-5) using the FRAIL index. …”
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44771
Comprehensive Analysis of Word Embedding Models and Design of Effective Feature Vector for Classification of Amazon Product Reviews
Published 2025-01-01“…This study examines the implementation of different traditional feature extraction models such as Bag of Words (BoW), Term Frequency-Inverse Document Frequency (TF-IDF), N-grams, and word embeddings like Word2Vec and Bidirectional Encoder Representations from Transformers (BERT) on an Amazon review dataset. …”
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Contribution of the Geodiversity knowledge to social, economic, and environmental health development
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44775
Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin
Published 2025-01-01“…The mutated hydrophobic residue in the α4 helix of hsPEX19 variants binds to the N17 domain of mHttex1, thereby inhibiting the initial aggregation process. …”
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Acoustic Analysis of Mandarin Chinese Vowels Produced by Young Adults
Published 2020-06-01“…The aim of the present study was to establish the vowel formant space by examining the formant frequencies associated with Mandarin vowels produced by Chinese young adults aged 23 to 33 years old and identify the characteristics of vowels in Mandarin Chinese at 4 different lexical tones.Methods:Acoustic signals of the six Mandarin vowels (/a/,/ɔ/,/e/,/i/,/u/,/y/) produced by native young adult speakers of Mandarin Chinese (<italic>n</italic>=11) were recorded, and the participants were instructed to produce all the speech samples using a comfortable loudness level and speech rate. …”
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A Bioclinical Pattern for the Early Diagnosis of Cardioembolic Stroke
Published 2014-01-01“…We aim to evaluate if plasma biomarkers can predict stroke subtypes in the early phase from stroke onset. Methods. Plasma N-terminal prohormone of brain natriuretic peptide (NT-proBNP), D-dimer, C-reactive protein, serum albumin, and globulin levels have been investigated in 114 consecutive patients presenting at the emergency room within 6 hours of the ischemic stroke onset. …”
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