A meta-analysis and systematic review of the clinical efficacy and safety of platelet-rich plasma combined with hyaluronic acid (PRP + HA) versus PRP monotherapy for knee osteoarth... by Dan Du, Yuan Liang

“…Results This meta-analysis of 11 RCTs (n = 1023 KOA patients) revealed that PRP + HA has substantial effectiveness than PRP alone in reducing OMAC total scores [MD -1.77 (95% CI -2.20 to − 1.34); I2 = 10%, and p < 0.001], VAS scores [MD -4.27 (95% CI -4.96 to − 3.58); I2 = 13%, and p < 0.001], and Lequesne index score [MD -5.48 (95% CI -6.56 to − 4.40); I2 = 16%, and p < 0.001], while increasing IKDC scores [MD -2.10 (95% CI -3.70 to − 0.50); I2 = 9%, and p = 0.01], with low risk of adverse events [RR 0.41 (95% CI 0.35 to 0.48); I2 = 12%, and p < 0.001]. …”
Get full text

Facilitators and barriers of alcohol goals for Latinx men hospitalized with alcohol use disorder seen by an Addiction Consult Team by Mariam S. Carson, Alein Y. Haro-Ramos, Naomi López-Solano, Carla Fernandez, Marcus Cummins, Alicia Fernandez, Triveni DeFries, Marlene Martin

“…We recorded and transcribed interviews and used a mixed deductive and inductive analytic approach until we reached thematic saturation (n = 10).Results We identified three major themes: 1. …”
Get full text

碗扣式钢管支撑架不同构造形式节点的转动刚度试验研究 by 张金轮, 张阿祥, 王家伟

“…研究结果表明：（1） 碗扣式钢管支撑架角节点、边节点的转动刚度分别为中间节点转动刚度的77.93%、92.14%，且均高于规范给出的建议值25 kN·m∙rad^-1；角节点与边节点的转动刚度相对较弱，对架体整体稳定性的影响不可忽略；（2） 当地市场随机采购的碗扣式钢管的弹性模量较新构件有不同程度的下降，最大降幅约为30%；（3） 碗扣式节点的破坏先后顺序为水平杆、上碗扣、立杆和下碗扣；节点的破坏发生在水平杆接头处，应对此处加强质量监管。…”
Get full text

Breaking the cycle: a pilot study on autonomous Digital CBTe for recurrent binge eating by Rebecca Murphy, Charandeep Khera, Emma L. Osborne

“…Those who completed all sessions and the post-intervention assessment (n = 55, 50%) reported significant decreases in binge eating, eating disorder psychopathology, and secondary impairment at post-intervention. …”
Get full text

Rigid‐Flexible Coupling Realized by Synergistic Engineering of the Graphitic‐Amorphous Architecture for Durable and Fast Potassium Storage by Mingchi Jiang, Ning Sun, Bin Cao, Xuyang Jian, Razium Ali Soomro, Bin Xu

Get full text

Impact of predictive selection of LbCas12a CRISPR RNAs upon on‐ and off‐target editing rates in soybean by Linda Rymarquis, Chenxi Wu, Diane Hohorst, Miguel Vega‐Sanchez, Thomas E. Mullen, Vijetha Vemulapalli, Douglas R. Smith

Get full text

The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages by Hwa-Jin Chung, Wonil Koh, Won Kyung Kim, Joon-Shik Shin, Jinho Lee, Sang Kook Lee, In-Hyuk Ha

“…Three mechanisms explaining the effects of Shinbaro3 in RAW 264.7 cells were identified as follows: (1) inhibition of the extracellular signal-regulated kinase 1 and 2 (ERK1/2), stress-activated protein kinase (SAPK)/c-Jun N-terminal protein kinase (JNK), and p38 mitogen-activated protein kinase (MAPK) pathways; (2) suppression of IκB kinase-α/β (IKK-α/β) phosphorylation and nuclear factor-kappa B (NF-κB) subunits in the NF-κB pathway, which are involved in MyD88-dependent signalling; and (3) downregulation of IFN-β mRNA expression via inhibition of interferon regulatory factor 3 (IRF3) and Janus-activated kinase 1 (JAK1)/signal transducer and activator of transcription 1 (STAT1) phosphorylation, which is involved in TRIF-dependent signalling. …”
Get full text

Competitividade e estratégia: novos desafios para coordenadores de cursos de IES privadas no Brasil by Patrícia Guimarães Rocha Saboya, Fernando Antônio Colares Palácios, Márcia Athayde Moreira, Naiara Silva Ferreira

Get full text

Forensic tactics: a review of the formation history and current trends by O. P. Shaituro

Get full text

Surgical Quality in Rectal Cancer Management: What Can Be Achieved by a Voluntary Observational Study? by Łukasz Dziki, Ronny Otto, Hans Lippert, Paweł Mroczkowski, Olof Jannasch

“…The following parameters were analysed: (1) patient related: age, gender, ASA classification, T-stage, and N-stage, (2) system related: frequency of preoperative CT and MRI, and (3) outcome related: CRM status, complications, and hospital mortality. …”
Get full text

Manejo de enmiendas para restaurar la materia orgánica del suelo en oasis de regadío de Mendoza, Argentina by A. ABRIL, L. NOE, M.F. FILIPPINI

“…El contenido de MO aumentó en el 40% de los casos analizados (n=92) y no sufrió modificaciones en el resto, mientras que los ácidos fúlvicos también aumentaron en el 40% de los casos, pero disminuyeron en el 30%. …”
Get full text

Efficacy of Knee Taping in addition to a Supervised Exercise Protocol to Manage Pain and Functional Status in Individuals with Patellofemoral Osteoarthritis: A Randomized, Controll... by Mudasir Nazar Shah, Mohammad Abu Shaphe, Mohammed Qasheesh, Mohammad Kashif Reza, Ahmad H. Alghadir, Amir Iqbal, Priyadarshani Bhat

“…Following an initial screening, forty people with PF OA (mean age 55, range 40–60) were randomly assigned to one of two groups, Group A or Group B (n = 20 each). Group A underwent knee taping and participated in a supervised exercise program, whereas Group B only participated in a supervised exercise program. …”
Get full text

Comparison of CT-Guided Microwave Ablation of Liver Malignancies with and Without Intra-Arterial Catheter Placement for Contrast Administration by Anne Bettina Beeskow, Holger Gößmann, Hans-Jonas Meyer, Daniel Seehofer, Thomas Berg, Florian van Bömmel, Aaron Schindler, Manuel Florian Struck, Timm Denecke, Sebastian Ebel

“…The patients with an IA catheter (<i>n</i> = 25) received an IA application of 10 mL CM. …”
Get full text

Development of a Sensitive Chemiluminescence Immunoassay for the Quantification of Folic Acid in Human Serum by Xiang Chen, Qiyang Zhou, Ting Zhang, ChunXin Wang, Zheng Yu, Hadji Ahamada, Zhonghu Bai, Xuan Huang

“…Streptavidin (SA) was labeled to magnetic beads by an 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide (EDAC/NHS) method. Activated biotin molecules were labeled to FBP molecules purified from milk. …”
Get full text

Des métamorphoses de l’aura by Alain Naze

“…Si la résorption du caractère expressif de la réalité au sein d’un univers instrumental, pour Pasolini, empêche de recourir encore à la transparence des grands poèmes du cinéma classique, de même que la disparition des grandes figures du narrateur, pour Benjamin, coupe la voie vers la narration en ses formes traditionnelles, pourtant, tous deux s’accordent pour reconnaître que, loin de devoir déplorer cet état de fait, il s’agirait de prendre acte de l’appareillage spécifique de notre époque, notamment en exhibant – à des fins, politiques, de démystification – l’intégration de la technique cinématographique à notre réalité.Des types spécifiques de récit restent donc possibles pour notre époque, signe que le récit en tant que tel est capable de résister à la perte d’autorité de ses formes traditionnelles, qui auraient eu à subir l’apparent dépérissement moderne de l’aura. Si le cinéma n’est certes pas appareil de narration, son esthétique du choc semble malgré tout compatible avec des modalités rénovées du récit, et d’abord avec des modalités assumant le fait que tout effet de naturalité doive dériver d’un surcroît de technique. …”
Get full text

The Role of Youth Social Activity in the Expression of Identities and their Consistency by R.M. Shamionov, E.E. Bocharova

Get full text

Direct-Acting Antivirals in Hepatitis C Treatment for Renal Impairment: Liver Safety Concerns and Effectiveness in Peritoneal Dialysis by Hsuan-Yu Hung, Wei-Liang Hung, Ye Gu, Chung-Yu Chen

“…All peritoneal dialysis patients (<i>n</i> = 10) achieved a 100% SVR12 rate. <b>Conclusions:</b> This real-world study supports the effectiveness of G/P and EBR/GZR in peritoneal dialysis patients. …”
Get full text

Influences of Solar Wind Parameters on Energetic Electron Fluxes at Geosynchronous Orbit Revealed by the Deep SHAP Method by Jianhang Wang, Zheng Xiang, Binbin Ni, Deyu Guo, Yangxizi Liu, Junhu Dong, Jingle Hu, Haozhi Guo

Get full text

Fostering active choice to empower behavioral change to reduce cardiovascular risk: A web-based randomized controlled trial. by Lorraine L Landais, Judith G M Jelsma, Olga C Damman, Evert A L M Verhagen, Danielle R M Timmermans

“…<h4>Methods</h4>Adults aged 50-70 (n = 743) without CVD history participated in this web-based randomized controlled trial. …”
Get full text

Effects of long-term adapted physical training on functional capacity and quality of life in older adults with Parkinson's disease by Oussama Gaied Chortane, Elmoetez Magtouf, Wael Maktouf, Sabri Gaied Chortane

“…Although physical activity is considered a therapeutic treatment to slow the progression of the disease, it is considered to be an effective non-pharmacological adjuvant to medication to improve the symptom management.MethodsThe training program was offered for all the participants (N = 50) in three non-consecutive sessions per week for 60 minutes and a total duration of 12 to 16 months. …”
Get full text