激活核因子Ｅ２相关因子２信号通路减轻高糖诱导足细胞的凋亡

“…【方法】体外培养小鼠足细胞，分为５组：对照组、高渗组、高糖组、高糖＋叔丁基对苯二酚（ ｔＢＨＱ），高糖＋Ｎ－乙酰半胱氨酸（ＮＡＣ）。流式细胞仪检测细胞内活性氧和凋亡；Ｗｅｓｔｅｒｎ ｂｌｏｔ 及ｒｅａｌ ｔｉｍｅ－ ＰＣＲ检测Ｎｒｆ２、醌氧化还原酶１（ＮＱＯ１），血红素加氧酶（ＨＯ－１）的表达；检测足细胞丙二醛（ＭＤＡ）、超氧化物歧化酶（ＳＯＤ）、谷胱甘肽（ＧＳＨ）及过氧化氢酶（ＣＡＴ）。…”
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Antimicrobial Activity of Thermocycled Polymethyl Methacrylate Resin Reinforced with Titanium Dioxide and Copper Oxide Nanoparticles by Rashin Giti, Kamiar Zomorodian, Maryam Firouzmandi, Zahra Zareshahrabadi, Sedigheh Rahmannasab

“…In this in vitro study, 150 disk-shaped (10 × 2 mm) specimens of heat-cured PMMA were prepared and divided into five groups (n = 30) to be reinforced with 2.5% CuO, 7.5% CuO, 2.5% TiO2, or 7.5% TiO2 nanoparticles and a control group (without nanoparticle). …”
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Epidemiology of Brucellosis in Small Ruminants of Rural and Peri-Urban Areas of Multan, Pakistan by Mian Muhammad Awais, Bakhtawar Khadim, Masood Akhtar, Muhammad Irfan Anwar, Gohar Khadim, Abdul Sammad Ali Khan Shirwany, Halil Selcuk Biricik, Abdul Razzaq, Muhammad Sibtain Bhatti

“…For this purpose, sera samples (n = 392) of small ruminants were collected and subjected to preliminary screening using commercially available RBPT reagents followed by serodetection of brucellosis using multispecies i-ELISA kit (ID.vet, France). …”
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Етапна організація навчання інтегрованих умінь читання та письма учнів профільної школи на прикладі есе... by Вікторія Осідак, Ясинецька Владислава

“…Учасниками дослідження стали учні 11-го класу (n = 10). Навчання охоплювало виконання підсистеми завдань, що передбачало активне залучення учнів до аналізу текстів, виявлення ключових ідей, їх порівняння та протиставлення, а також інтеграцію цих ідей у порівняльно-зіставному есе. …”
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Statistical exploration of factors associated with birth of children having sickle cell traits among reproductive-age women in Nigeria by Gabriel Ogunde, Ayodele Shabi, Joshua O. Akinyemi

“…Mothers with at least one under-five child whose genotype was known (n = 7,493) served as the unit of analysis. Three forms of outcome variable were explored. …”
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Development of a Conceptual Model to Understand Disease Burden in Patients With Systemic Lupus Erythematosus and Organ Damage by Lynne Broderick, Wen-Hung Chen, Roger A. Levy, April Mitchell Foster, Cindy Umanzor Figueroa, Kerry Gairy, Deven Chauhan

“…Participants with SLE-associated OD (n = 40) experienced detrimental impacts across 4 areas of their lives: physical, cognitive, psychosocial functioning, and economic and work-related well-being. …”
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Care for post-COVID-19 condition in Germany from the perspectives of patients, informal caregivers and general practitioners: Study protocol for a mixed methods study. by Melanie Brinkmann, Maike Stolz, Annika Herr, Christoph Herrmann-Lingen, Imke Koch, Christiane Müller, Frank Müller, Uta Sekanina, Jona Theodor Stahmeyer, Martina de Zwaan, Christian Krauth, Nils Schneider

“…Additional data sources will be claims data (n = 27,275) and 25-30 semi-structured interviews. …”
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Identification and Prediction of Allo-Source Overpressure Caused by Vertical Transfer: Example from an HTHP Gas Reservoir in the Ledong Slope in the Yinggehai Basin by Caiwei Fan, Changgui Xu, Chao Li, Aiqun Liu, Hu Li, Jingxian Hou, Xiaoying Zhang, Bin Lu, Jun Li

“…The high-magnitude overpressure fluid generated by the high mature ultradeep buried N1s source rock migrated to the shallower reservoirs via hidden faults/microfractures, which led to the vertical transfer of overpressure. …”
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Vieillesse, savoir et genre. Réflexions sur les discours consacrés à la vieillesse dans l'Antiquité by Beate Wagner-Hasel

“…Cette approche est ici contestée comme l’émanation d’une expression littéraire qui n’a pas valeur de description réaliste, ou historique, de l’expérience de la vieillesse et des normes sociétales en vigueur dans l’Antiquité. …”
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Compressive Strength of Fly-Ash-Based Geopolymer Concrete by Gene Expression Programming and Random Forest by Mohsin Ali Khan, Shazim Ali Memon, Furqan Farooq, Muhammad Faisal Javed, Fahid Aslam, Rayed Alyousef

“…The influential parameters that are considered as input variables for modelling are curing temperature T, curing time t, age of the specimen A, the molarity of NaOH solution M, percent SiO2 solids to water ratio % S/W in sodium silicate (Na2SiO3) solution, percent volume of total aggregate ( % AG), fine aggregate to the total aggregate ratio F/AG, sodium oxide (Na2O) to water ratio N/W in Na2SiO3 solution, alkali or activator to the FA ratio AL/FA, Na2SiO3 to NaOH ratio Ns/No, percent plasticizer (% P), and extra water added as percent FA EW%. …”
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Assessing the impact of paternal emigration on children ‘left-behind’—A cohort analysis by Natalia Norori, Lucy Barrass, Maria Theresa Redaniel, Nanette R. Lee, Laura D. Howe, Duleeka Knipe

“…Methods: Using data from the Cebu Longitudinal Health and Nutrition Survey cohort (n = 1651), we assessed the association of paternal emigration (identified based on evidence of remittances sent back by mother's spouse) during childhood with the mental health and educational attainment at age 18 of Filipino children, adjusted for sex, socioeconomic position and paternal education. …”
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Digital competencies: perceptions of primary school teachers pursuing master’s degrees from eight African countries by Andresa Sartor Harada, Juliana Azevedo Gomes, Oscar Ulloa Guerra, Roberto Ruiz, Rubén Calderón

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Xanthohumol and echinocystic acid induces PSTVd tolerance in tomato by Wenkun Tang, Zhichao Tang, Haiyi Liu, Jinbiao Lu, Qianyun Du, Huan Tian, Jingwei Li

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Sex differences in the relationship between maternal and foetal glucocorticoids in a free-ranging large mammal by Amin, Bawan, Fishman, Ruth, Quinn, Matthew, Matas, Devorah, Palme, Rupert, Koren, Lee, Ciuti, Simone

“…These were then related to GC levels from hair of their neonate offspring (n = 40). We have shown that maternal GC levels were positively associated with foetal GC levels, but only in female offspring. …”
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Health-related physical fitness in children among five Mediterranean countries: a cross-cultural study from the DELICIOUS project by Mohamed Aly, Noha El-Gyar, Amira M. Shalaby, Osama Abdelkarim

“…This study explored cross-cultural variations in HRF among children from five Mediterranean countries—Egypt, Italy, Lebanon, Portugal, and Spain—within the framework of the DELICIOUS project.MethodsA total of 860 children participated in the study, including 204 from Egypt (n = 204, 11.72 ± 1.46 years), 150 from Italy (9.66 ± 1.10 years), 200 from Lebanon (10.73 ± 1.90 years), 181 from Portugal (11.04 ± 1.83 years), and 125 from Spain (12.33 ± 2.27 years). …”
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Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature by A. Ibrahim, A. Luk, P. Singhal, Bo Wan, A. Zavodni, R. J. Cusimano, J. Butany

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Effects of twelve-week aerobic exercise on selected health-related physical fitness variables on Gonji preparatory school male students by Abdurahman Esleman, Bizuneh Yirga Geberemariam, Wondiye Aychiluhim

“…A simple random sampling method was used to select 30 sample students from the 242 total populations and classify them randomly into two equal experimental and control groups (n = 15). The Control group had participated in regular physical education one class of  40-minute per week in the school, but the experimental group participated additional three sessions per week for 60 minutes aerobic exercise training program, which comprised walking, jogging, running, rope skipping, and aerobic dance. …”
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A Thirty-Year Follow-Up Surveillance Study for Neoplasia of a Dutch Ulcerative Colitis Cohort by J. A. M. Stolwijk, A. M. J. Langers, J. C. Hardwick, R. A. Veenendaal, H. W. Verspaget, R. A. van Hogezand, H. F. Vasen, A. E. van der Meulen-de Jong

“…Patients with pancolitis (n=178) had a significantly higher cumulative risk of dysplasia than patients with distal disease, HR 1.9 (95%CI 1.1–3.3). …”
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Adult Wilms Tumor With Inferior Vena Cava Thrombus on an Incomplete Duplex Collecting System Ureter Fissus Proximalis Managed at a Tertiary Hospital in Tanzania: A Case Report and... by Amini Mitamo Alexandre, Joseph Martin Lori, Gabriel F. Mtaturu, Victor Patrick Sensa, Sylvia Bedas Nsato, Mariam Athumani Mbezi, Obadia V. Nyongole, Charles A. Mkony

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Evaluation of an aquatic liverwort and terrestrial moss as biomonitors of heavy metals associated with particulate matter by Clara Gómez-Ensastegui, Pedro Avila-Pérez, José Luis García-Rivas, Carlos Eduardo Barrera-Díaz, Huemantzin Balan Ortiz-Oliveros, Sonia Martínez-Gallegos

“…The results show that mainly the functional groups -OH and -NH, N-H and C-O on the surface of the liverwort and moss participate in the adsorption of heavy elements. …”
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