The mediating role of accelerated biological aging in the association between household air pollution from solid cooking fuels and neuropsychiatric disorders by Rui Tang, Haisheng Wu, Ling Jiang, Jie Zhou, Xia Gao, Jiazhen Zheng, Ya-Ping Tang, Mingxi Tang

“…Leisure engagement demonstrated stable benefits in attenuating KDM-BAA independently of cooking fuel use. Conclusion: Our findings illuminate the pathways connecting HAP from solid fuel consumption with biological aging and neuropsychiatric disorders, and highlight the role of leisure engagement and expanding access to cleaner fuels in mitigating these adverse effects.…”
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Development and validation of a risk prediction model for PICC-related venous thrombosis in patients with cancer: a prospective cohort study by Zeyin Hu, Mengna Luo, Ruoying He, Zhenming Wu, Yuying Fan, Jia Li

“…Univariate and multivariate regression analyses were used to identify independently associated risk factors of PICC-RVT and develop a risk prediction model. 275 patients were finally included for data analysis, and 18 (6.5%) developed PICC-RVT. …”
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A synergistic effect of secondhand smoke with vitamin D deficiency on cognitive impairment in older adults: a cross sectional study by Yan Li, Qianqian Shen, Chengyu Chen, Xueru Yin, Xinru Wang, Xiyue Yang, Xueqian Zhang, Lei Chen, Jian Xu, Guifang Gong

“…The possible synergistic effect of SHS with VDD on cognitive impairment was evaluated by using a multivariable logistic regression model.ResultsVDD was independently associated with risk of low the Digit Symbol Substitution Test (DSST) scores, increased by nearly 60% [< 34, adjusted odds ratio (aOR) = 1.62, 95% CI: 1.03 ~ 2.53]. …”
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Practice and factors affecting informed consent among healthcare workers for major surgical procedures at Gurage zone hospitals, South Ethiopia, 2022: a facility-based cross-sectio... by Haimanot Abebe, Bitew Tefera Zewudie, Yibeltal Mesfin, Shegaw Geze Tenaw, Daniel Tsega, Bogale Chekole, Zebene Mekonnen, Shegaw Tesfa Mengist, Agere Aynalem, Tadele Lankrew, Yihenew Sewale, Muche Argaw, Tadesse Sahle

“…In multivariable logistic analysis model, factors like favourable attitude towards informed consent 2.4 (1.556, 3.596), work experience participants 4.9 (2.8, 8.7), adequate knowledge of informed consent 2.5 (1.6, 3.9) and communication challenge 1.6 (1.07, 2.50) were independently associated with the practice of informed consent at a p value of <0.05.Conclusion More than half of healthcare providers had good practice towards the surgical informed consent process. …”
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Strain rebound and inhomogeneity in glass-to-metal seals: Radial vs axial strain evolution by Keqian Gong, Zheng Liu, Zifeng Song, Chao Zhou, Zhangjing Shi, Siyue Nie, Weisong Zhou, He Yan, Zhichun Fan, Yong Zhang

“…This study employs advanced fiber Bragg grating (FBG) in situ monitoring to decouple and independently analyze radial and axial strain evolution, providing novel insights into the mechanical anisotropy of sealing glass. …”
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Impact of obesity on iron metabolism and the effect of intravenous iron supplementation in obese patients with absolute iron deficiency by Laura Tarancon-Diez, Marianela Iriarte-Gahete, Pilar Sanchez-Mingo, Mª Ángeles Muñoz-Fernandez, Maria Luisa Navarro-Gomez, Yolanda M. Pacheco, Manuel Leal

“…Obese group exhibited higher levels of ferritin, hemoglobin (Hb), soluble transferrin receptor (sTfR) and hepcidin compared to HW group. Elevated BMI was independently associated with increased sTfR levels. …”
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Comparison of MRI and CT in the Evaluation of Unilateral Maxillary Sinus Opacification by Elise Chua, Annakan V. Navaratnam, Dominic St Leger, Vincent Lam, Samit Unadkat, Alexander Weller

“…Two head and neck radiologists independently reviewed each imaging modality and recorded both a final diagnosis and Likert-scale diagnostic certainty score. …”
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HIV Drug Resistance Profile in Clients Experiencing Treatment Failure After the Transition to a Dolutegravir-Based First-Line Antiretroviral Treatment Regimen in Mozambique by Nalia Ismael, Cidia Hussein, Cacildo Magul, Humberto Inguane, Aleny Couto, Amancio Nhangave, Ana Muteerwa, Mahoudo Bonou, Artur Ramos, Peter Wesley Young, Sonia Chilundo, Rhoderick Machekano, Lauren Greenberg, Juliana da Silva, Nilesh Bhatt

“…Unsuppressed VL before DTG transition was independently associated with VF (aOR: 2.14). Resistance patterns included 33.3% (12/36; 95% CI: 14.6–46.3) to all three TLD drugs, 55.6% (20/36; 95% CI: 39.3–71.9) to DTG and 3TC, and 11% (4/36; 95% CI: 0.8–21.3) to DTG only. …”
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Android to gynoid fat ratio and its association with functional capacity in male patients with heart failure by Marcelo Rodrigues Dos Santos, Guilherme Wesley Peixoto daFonseca, Letícia Pironato Sherveninas, Francis Ribeiro deSouza, Antônio Carlos Battaglia Filho, Caio Eduardo Novaes, Rosa Maria Rodrigues Pereira, Carlos Eduardo Negrão, Antônio Carlos Pereira Barretto, Maria‐Janieire de Nazaré Nunes Alves

“…Logistic regression analysis showed A/G ratio >0.55 to be independently associated with reduced peak VO2 adjusted for age, body mass index, LVEF, presence of sarcopenia, anabolic hormones, and haemoglobin (odds ratio 3.895, 95% confidence interval 1.030–14.730, P = 0.045). …”
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Interleukin-18 Expression Increases in the Aorta and Plasma of Patients with Acute Aortic Dissection by Haiying Hu, Guangtai Zhang, Huanli Hu, Wenjing Liu, Jixiang Liu, Shuanli Xin, Xiufeng Zhao, Liying Han, Liping Duan, Xinshun Huang, Chao Chang

“…Linear regression analysis showed that the IL-18 level was independently associated with the presence of AD. In addition, anti-mouse IL-18-neutralizing monoclonal antibodies (anti-IL-18 nAb) inhibited angiotensin II-induced M1 macrophage differentiation and SMC apoptosis in vitro. …”
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Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson’s Disease by Daniel Martinez-Ramirez, Edna Sophia Velazquez-Avila, Alejandro Almaraz-Espinoza, Arnulfo Gonzalez-Cantú, Genaro Vazquez-Elizondo, Daniel Overa-Posada, Amin Cervantes-Arriaga, Mayela Rodriguez-Violante, Mirna Gonzalez-Gonzalez

“…A regression model identified variables that independently explained dysautonomic scores in our early PD cohort. …”
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Impact of finasteride on modulating the risk and clinical outcomes of bladder cancer: insights from a comprehensive meta-analysis by Ailing Yu, Ailing Yu, Ailing Yu, Ailing Yu, Ailing Yu, Zian Bai, Zian Bai, Zian Bai, Zian Bai, Yijie Wang, Yijie Wang, Yijie Wang, Yijie Wang, Zhen Luo, Zhen Luo, Zhen Luo, Zhen Luo, Xiaochen Du, Mengxin Chen, Shuang Wen, Honglong Wang, Xiaoying Yuan, Chunyu Yang, Shanshan Bai, Bo Fan, Bo Fan, Bo Fan, Bo Fan

“…Data was extracted for further analysis by two different reviewers who independently examined the titles and abstracts of the included articles. …”
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Incidence of cancer-related lymphoedema: a protocol for a living systematic review with meta-analysis by Nele Devoogdt, Hildegard Reul-Hirche, Kira Bloomquist, Michael Bernas, Ben Singh, Sandi Hayes, Melanie Plinsinga, Debbie Geyer, Louise Koelmeyer, Neil Piller, Stanley Rockson

“…Two investigators will independently extract data and assess the risk of bias using the Cochrane Risk of Bias Tool Version 2.0, the Risk of Bias in Non-randomised Studies – of Interventions or the National Institutes of Health Heart, Lung and Blood Institute Study Quality Assessment Tools, depending on study design. …”
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Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells by Masahiko Kutsukake, Naoko Kuwabara, Yoshikazu Miyate, Kenzo Kudo, Shoko Goto, Eiichi Taira, Eiichi Tachikawa

“…However, whether their second messengers cooperatively or independently participate in steroid production remains unclear. …”
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Functional and Structural Investigation of Myenteric Neurons in the Human Colon by Kristin Elfers, Alina Sophia Sehnert, Alexander Wagner, Ulrich Zwirner, Helena Linge, Ulf Kulik, Daniel Poehnert, Markus Winny, Benjamin Gundert, Heiko Aselmann, Gemma Mazzuoli-Weber

“…Background and Aims: The enteric nervous system independently controls gastrointestinal function including motility, which is primarily mediated by the myenteric plexus, therefore also playing a crucial role in functional intestinal disorders. …”
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PPAR-α Agonist Fenofibrate Decreased Serum Irisin Levels in Type 2 Diabetes Patients with Hypertriglyceridemia by Xiaomeng Feng, Xia Gao, Yumei Jia, Heng Zhang, Qingrong Pan, Zhi Yao, Ning Yang, Jia Liu, Yuan Xu, Guang Wang, Xinchun Yang

“…In multiple regression analysis after controlling for confounders, only fasting blood glucose (β=5.615, P<0.001) and high-density lipoprotein cholesterol (β=19.483, P<0.001) were independently related to serum irisin. After 8 weeks of fenofibrate treatment, serum irisin significantly decreased in group A compared with baseline (45.15±10.48 versus 38.74±12.54 ng/ml, P=0.011). …”
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Radiofrequency ablation vs. cryoablation for pediatric atrioventricular nodal reentrant tachycardia in the era of three-dimensional electroanatomical mapping by Yao-Wei Chan, Chieh-Mao Chuang, Chieh-Mao Chuang, Pi-Chang Lee, I-Hsin Tai, I-Hsin Tai, I-Hsin Tai, Ying-Hsuan Peng, Ying-Hsuan Peng, Wen-Po Fan, Wen-Po Fan, Yu-Shin Lee, Ming-Chih Lin, Ming-Chih Lin, Sheng-Ling Jan, Sheng-Ling Jan, Yun-Ching Fu, Yun-Ching Fu, Shih-Ann Chen, Shih-Ann Chen

“…Ablation outside the low Koch triangle and cryoablation were independently associated with longer procedure times. …”
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Phenotypic age mediates the associations between platelet-to-lymphocyte ratio and all-cause and cause-specific mortality: A prospective cohort study by Xiangjun Li, Jia Wang, Mengqi Zhang, Yujing Li, Xiaoxuan Li, Jiaqi Zhang, Lihua Zhang, Yixuan Zhang, Zhenkang Qiu

“…Conclusion: The PLR, a valuable index that should be recommended for use, was independently linked with all-cause and cause-specific mortality, with PhenoAge playing a partial mediating role in the relationships.…”
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Arbuscular mycorrhizal colonization defines root ecological strategies in an extreme arid environment by Cristian A. Delpiano, Cristian A. Delpiano, Cristian A. Delpiano, Rodrigo S. Rios, Rodrigo S. Rios, Rodrigo S. Rios, Claudia E. Barraza-Zepeda, Melissa J. Pozo, Lorgio E. Aguilera, Andrea P. Loayza, Andrea P. Loayza, Andrea P. Loayza

“…At one end of this gradient, species with larger root diameters (RD) rely on colM for resource acquisition through an ‘outsourcing’ strategy, while at the other end, species with finer roots and greater exploration capacity employ a ‘do it yourself’ strategy to acquire resources independently. Although the RES framework has improved our understanding of root strategies, the relationship between colM and root traits in desert ecosystems remains underexplored, particularly in hyper-arid environments, where limited resources can constrain both plant and mycorrhizal survival. …”
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3D modeling to predict vascular involvement in resectable pancreatic adenocarcinoma by Sguinzi R, Vidal J, Poroes F, Bartolucci DA, Litchinko A, Gossin E, Fingerhut A, Toso C, Buhler L, Egger B

“…Two radiologists specialized in pancreatic imaging and two pancreatic surgeons blindly and independently analyzed the pre-operative CT scans and 3D models using a defined checklist. …”
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