Tracheostomy-related indications, early complications and their predictors among patients in low resource settings: a prospective cohort study in the pre-COVID-19 era by Nyanzi, Daniel J., Daniel, Atwine, Kamoga, Ronald, Birungi, Caroline, Nansubuga, Caroline A., Nyaiteera, Victoria, Nakku, Doreen

“…Overall, 53% (95% CI: 43.0 – 62.7) had early complications with the commonest being tube obstruction (52.6%). Independent pre dictors of early tracheostomy-related complications were; anticipated prolonged intubation as an indication (RR=1.8, 95%CI: 1.19 – 2.76), Bjork fap tracheal incision (RR=1.6, 95%CI: 1.09 – 2.43), vertical tracheal incision (RR=1.53, 95%CI: 1.02 – 2.27), and age below 18 years (RR=1.22, 95%CI: 1.00 – 1.47). …”
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Effect of Gender Equality on Economic Development of Household Heads in Uganda: A Case Study of Rwamucucu Sub-County, Rukiga District. by Nsimire, Millicent

“…There was critical review of the issues that have explored and studied both theoretically and empirically in the existing literature on of gender equality as an independent variable economic development as the dependent variable and the methods of data collection were put into action. …”
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The Effects of Genocide on Tourism Industry in Bugesera District in Rwanda. by Egide, Mudaheranwa

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Presenting a Model of Self-sacrificial behaviors of Leaders in Organizations; Interpretive Structural Modeling (ISM) Method by Amir Hossein Abdallahzadeh, Seyyed Mohammad Moghimi, Hossein Imani

“…These components are considered dynamic, meaning that any change in them can impact the entire system. The independent region includes five components: "goal orientation and idealism," "collective identity," "social learning and social contagion," "core values," and "crisis," indicating their strong influence and guiding role in the model. …”
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SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation by Ryan T. Wagner, Ryan A. Hlady, Xiaoyu Pan, Liguo Wang, Sungho Kim, Xia Zhao, Louis Y. El Khoury, Shafiq Shaikh, Jian Zhong, Jeong-Heon Lee, Jolanta Grembecka, Tomasz Cierpicki, Thai H. Ho, Keith D. Robertson

“…Mapping of genomic H3K36me2 targeting by NSD1 and NSD2 individually highlights the independent functions of these epigenetic writers. Furthermore, as a proof-of-principle, we demonstrate the therapeutic feasibility of targeting this synthetic lethal interaction by recapitulating the phenotype using BT5, a first-in-class pharmacologic inhibitor against NSD1. …”
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Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development by Monique Evelyn Ueberall, Martina Berchthold, Cécile Häberli, Sven Lindemann, Thomas Spangenberg, Jennifer Keiser, Christoph G. Grevelding

“…Conclusions In two independent in vitro screening approaches against two stages of S. mansoni one common interesting structure with rapid effects was identified, OGHL00022, which provides opportunities for further development. …”
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The clinical role of blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C by Yekaterina Ye. Starostina, M. V. Sokolova, L. M. Samokhodskaya, T. П. Rozina, T. N. Krasnova, Ye. B. Yarovaya, N. A. Mukhin

“…The multifactor analysis at comparison of patients with CGV and without it revealed the quantity of mutant alleles of PAI-675 5G/4G and ITGB3 1565 T/C genes and infection duration as independent factors for vasculitis development, while at comparison of patients with CGV and ACG - only quantity of mutant alleles of these genes. …”
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A multicenter, cross‐sectional analysis to assess the safety and usage pattern of brivaracetam in the management of partial‐onset seizure with BAEs—BREEZE study: A post‐hoc analysi... by Arvind Sharma, Krishnaprasad Korukonda, Amit Haldar, Usha Kant Misra, R. V. Anand, Yakshdeep Dave, Girish Kulkarni

“…The study was approved by central independent ethics committee. Descriptive and analytical statistics employed using SPSS version 29.0.1.0. …”
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The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity by Cuong J. Tran, Zahra Zubair-Nizami, Ingeborg M. Langohr, Matthew D. Welch

“…R. parkeri invades host cells, escapes from vacuoles into the cytosol, and undergoes two independent modes of actin-based motility mediated by effectors RickA or Sca2. …”
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A model based cost-utility analysis of Embedding referral to structured self-management education into standard practice (Embedding) compared to usual care for people with type 2 d... by Melanie J Davies, Alan Brennan, Danielle H Bodicoat, Daniel John Pollard, Anju Keetharuth, Michelle Hadjiconstantinou, Agnieszka Glab, Joesph P Mensa, Alison Northern

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Fighting Alzheimer’s with Movement: The Role of Physical Activity in Disease Management by Agnieszka Kosińska, Magdalena Balwierz, Karolina Kalinowska, Urszula Świrk, Jan Karczmarz, Joanna Orzechowska, Marika Gutowska, Michał Orzechowski, Aleksandra Paprocka, Paulina Fijałek

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Center-Related Variation in Hospitalization Cost for Patients Undergoing Percutaneous Left Atrial Appendage Occlusion by Shivaraj Patil, MD, Chaitanya Rojulpote, MD, Abhijit Bhattaru, BS, Avica Atri, MD, Krishna Vamsi Rojulpote, BS, Ola Khraisha, MD, Viha Atri, MD, William Frick, MD, Tarek Nafee, MD, Kishore Harjai, MD, Sumeet Mainigi, MD, Chien-Jung Lin, PhD, MD

“…Centers with low procedural volume, occurrence of procedural complications, congestive heart failure, and length of stay were independent predictors of a high-cost hospitalization. …”
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The management and clinical outcome of paracetamol poisoning in South African adults: A single-centre retrospective review by C Kotze, J Swanepoel, E C Kruger, E Decloedt

“…Larger multicentre studies are needed to identify independent predictors of paracetamol-induced hepatoxicity and mortality in Africa. …”
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Pan-cancer characterization of m6A-mediated regulation of T cell exhaustion dynamics and clinical relevancies in human cancers by Weiping Ji, Ye Fang, Liwei Chen, Yitong Zheng, Yifei Pei, Changqiu Mei, Meng Zhou

“…Multivariate analysis confirmed the prognostic value of this classification independent of traditional clinical factors. Moreover, m6A-TEX crosstalk influenced responses to immune checkpoint blockade therapies. …”
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Decision-making under epistemic, strategic and institutional uncertainty during COVID-19: findings from a six-country empirical study by Clare Wenham, Alexandra L Phelan, Winifred Ukponu, Sumegha Asthana, Tahmina Shirin, Claire J Standley, Adachioma Chinonso Ihueze, Sanjana Mukherjee, Ibrahim B Gobir, Mohannad Al Nsour, JJ Woo, Mohammad Mushtuq Husain, Nevashan Govender, Roujia Lin, Sumit Asthana, Renee Vongai Mutare

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A Physics-Based Hyper Parameter Optimized Federated Multi-Layered Deep Learning Model for Intrusion Detection in IoT Networks by Chirag Jitendra Chandnani, Vedik Agarwal, Shlok Chetan Kulkarni, Aditya Aren, D. Geraldine Bessie Amali, Kathiravan Srinivasan

“…The experimental results indicate that the Fed-MLDL with Fed-RIME optimization exhibits the highest accuracy for independent and identically distributed datasets with the scores being 99.2% with CICIoT23, 98.1% with CICIoT22, 98.2% with ToN_IoT, 98.5% with Edge_IIoTset and, 98.6% with IoT-23 dataset respectively. …”
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The Role of Mature Brain-Derived Neurotrophic Factor and Its Precursor in Predicting Early-Onset Insomnia in Stroke Patients Experiencing Early Neurological Deterioration by Shi G, Yu P, Wang Z, Xu M, Guo M, Wang X, Zhou R

“…Multivariate logistic regression analysis revealed that male gender (p = 0.026), Hamilton Depression Rating Scale (HAMD) scores (p < 0.001), mBDNF (p = 0.009), and the mBDNF/proBDNF ratio (p < 0.001) were independent predictors of EOI in END patients. The areas under the curve (AUC) for mBDNF and the mBDNF/proBDNF ratio were 0.686 and 0.778, respectively.Conclusion: Our study identified a correlation between reduced mBDNF levels and a decreased mBDNF/proBDNF ratio with the development of EOI in END patients. …”
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Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endosc... by V. T. Ivashkin, I. V. Maev, P. V. Tsar’kov, M. P. Korolev, D. N. Andreev, E. K. Baranskaya, S. G. Burkov, A. A. Derinov, S. K. Efetov, T. L. Lapina, P. V. Pavlov, S. S. Pirogov, A. V. Tkachev, A. S. Trukhmanov, E. D. Fedorov, A. A. Sheptulin

“…Most cases of peptic ulcer are pathogenetically associated with the infection of H. pylori. PU can be an independent disease or represent symptomatic ulcers of the stomach and duodenum (medicinal, as a result of stress or endocrine pathologies, associated with chronic diseases of internal organs). …”
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Predictive value of enhanced CT and pathological indicators in lymph node metastasis in patients with gastric cancer based on GEE model by Ling Yang, Yingying Ding, Dafu Zhang, Guangjun Yang, Xingxiang Dong, Zhiping Zhang, Caixia Zhang, Wenjie Zhang, Youguo Dai, Zhenhui Li

“…Results Lymph node enhancement pattern, Ki67 level, and lymph node long-axis diameter were independent predictors of LNM in gastric cancer (p < 0.01). …”
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Bilateral alterations in sensorimotor function and altered sensory strategy in individuals with unilateral chronic ankle instability by Xiaomei Hu, Xihe Hou, Lin Wang

“…Except for SOT, all tests evaluated bilateral limbs, and the order of limbs was randomly selected. 2 (group) × 2 (limb) mixed model analyses of variance were performed for outcome measures of unilateral stance, Y balance and MCT, and independent t-test was used to analyse the outcomes of SOT between two groups. …”
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