Selection of terminal Piétrain pigs improves vitality and prevalence of congenital defects in crossbred piglets by Wim Gorssen, Wim Gorssen, Carmen Winters, Roel Meyermans, Léa Chapard, Katrijn Hooyberghs, Jaro De Kort, Alice Van den Broeke, Jürgen Depuydt, Steven Janssens, Nadine Buys

“…This study was based on two unique datasets with litter records collected between 2016 and 2024 on four independent commercial sow farms. The first dataset was collected by the breeding organization and consisted of 12,010 crossbred litters (Piétrain sire, hybrid dam; two farms) scored on piglets’ vitality, number of piglets with porcine congenital splay leg syndrome and scrotal hernia, pre-weaning mortality and the number of piglets born death. …”
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A dual role of Cohesin in DNA DSB repair by Michael Fedkenheuer, Yafang Shang, Seolkyoung Jung, Kevin Fedkenheuer, Solji Park, Davide Mazza, Robin Sebastian, Hiroyuki Nagashima, Dali Zong, Hua Tan, Sushil Kumar Jaiswal, Haiqing Fu, Anthony Cruz, Supriya V. Vartak, Jan Wisniewski, Vittorio Sartorelli, John J. O’Shea, Laura Elnitski, Andre Nussenzweig, Mirit I. Aladjem, Fei-Long Meng, Rafael Casellas

“…Second, cohesin has an architecture-independent role triggered by ATM phosphorylation of SMC1, which enhances the efficiency of repair. …”
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Multiparameter body composition analysis on chest CT predicts clinical outcomes in resectable non-small cell lung cancer by Yilong Huang, Hanxue Cun, Zhanglin Mou, Zhonghang Yu, Chunmei Du, Lan Luo, Yuanming Jiang, Yancui Zhu, Zhenguang Zhang, Xin Chen, Bo He, Zaiyi Liu

“…Conclusions SMI, IMAI, and SAI body composition metrics have been identified as independent prognostic factors and may indicate mortality risk for resectable NSCLC patients. …”
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Hubungan Pemberian ASI Eksklusif dengan Kejadian Diare pada Bayi di Wilayah Puskesmas Nanggalo Padang by Maretha Antya Tamimi, Yusri Dianne Jurnalis, Delmi Sulastri

“…</em><em>The result of Independent t-test shows that there’s no significant difference between the age</em><em> of first time diarrhea </em><em>in </em><em> exclusive breastfeeding infant</em><em>s</em><em> and no </em><em>exclusive </em><em>breastfeed</em><em>ing</em><em> infants</em><em> (p=0.593)</em><em>. …”
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Mendelian randomization and multiomics comprehensively reveal the causal relationship and potential mechanism between atrial fibrillation and gastric cancer by Zhao Sicheng, Zhao Sicheng, Zhang Jingcheng, Zhang Jingcheng, Zhang Shuo, Zhang Shuo, Lou Jiaheng, Lou Jiaheng, Cai Yan, Cai Yan, Bai Xing, Bai Xing, Jiang Tao, Jiang Tao, Jiang Tao, Zhang Guangji, Zhang Guangji, Zhang Guangji

“…High-throughput sequencing data were further used to analyze the association between the two and their impact on the survival outcome of gastric cancer.ResultsThe results showed that AF was negatively associated with gastric cancer, and further analysis revealed that this relationship was independent of GC risk factors such as chronic gastritis, Helicobacter pylori infection, and alcohol consumption. …”
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Comprehensive Analysis of m5C RNA Methylation Regulator Genes in Clear Cell Renal Cell Carcinoma by Jiajin Wu, Chao Hou, Yuhao Wang, Zhongyuan Wang, Pu Li, Zengjun Wang

“…According to the seven selected regulatory factors of m5C RNA methylation, a risk signature associated with m5C methylation that can independently predict prognosis in patients with ccRCC was developed and further verified the predictive efficiency.…”
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Effect of the season on blood changes of oxidative stress index (OSi) in the Italian Mediterranean Buffalo (Bubalis bubalis by Giovanna De Matteis, Emanuela Rossi, Maria Chiara La Mantia, Roberto Steri, Vittoria Lucia Barile, David Meo Zilio

“…In conclusion, this field study showed that OSi could be considered a better and independent marker of oxidative status in buffalo concerning the evaluation of single determinations of d-ROMs and BAP. …”
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Large-scale flood risk assessment in data-scarce areas: an application to Central Asia by P. Ceresa, G. Bussi, S. Denaro, G. Coccia, P. Bazzurro, P. Bazzurro, M. Martina, M. Martina, E. Fagà, C. Avelar, M. Ordaz, B. Huerta, O. Garay, Z. Raimbekova, K. Abdrakhmatov, S. Mirzokhonova, S. Mirzokhonova, V. Ismailov, V. Belikov

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Immunomodulatory Effects Mediated by Dopamine by Rodrigo Arreola, Samantha Alvarez-Herrera, Gilberto Pérez-Sánchez, Enrique Becerril-Villanueva, Carlos Cruz-Fuentes, Enrique Octavio Flores-Gutierrez, María Eugenia Garcés-Alvarez, Dora Luz de la Cruz-Aguilera, Emilio Medina-Rivero, Gabriela Hurtado-Alvarado, Saray Quintero-Fabián, Lenin Pavón

“…The peripheral and central nervous systems have independent dopaminergic system (DAS) that share mechanisms and molecular machinery. …”
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Barriers to healthcare access among female youths in Mozambique: a mixed-effects and spatial analysis using DHS 2022/23 data by Habtu Kifle Negash, Hiwot Tezera Endale, Hailu Aragie, Winta Tesfaye, Mihret Getnet, Tseganesh Asefa, Yibeltal Yismaw Gela, Alebachew Ferede Zegeye

“…Barriers were assessed based on finances, distance, permission, and safety, with independent variables like age, education, wealth index, marital status, and community factors. …”
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Implementation of PI-speed controller of DC motor by mathematical modeling by A. S. Semenov, Yu. V. Bebikhov, I. A. Yakushev, O. V. Fedorov

“…The main methods for controlling the required characteristics of the speed of rotation of a DC motor with independent excitation are to control the parameters of the armature and excitation windings fed from different sources. …”
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Clinical outcome changes in sarcopenic obesity: a meta-analysis of exercise training methods by Lei Chen, Haojing Zhou, Yichen Gong, Yi Tang, Hai Su, Zhongyi Zhang, Peijian Tong, Guoqian Chen

“…Abstract Aim Assessing the effect of various forms of exercise training on patients with sarcopenic obesity. Methods Two independent reviewers systematically searched English and Chinese databases (PubMed, Embase, Cochrane Library, Web of Science, CNKI) for randomized controlled trials on various exercise training effects in sarcopenic obesity patients until October 2023. …”
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Pengaruh Aplikasi Bahan Pemutih Gigi Karbamid Peroksida 10% dan Hidrogen Peroksida 6% secara Home Bleaching terhadap Kekerasan Permukaan Email Gigi by Meiyestri Dwi Riani, Fadil Oenzil, Nila Kasuma

“…Enamel hardness surface was measure by Vickers Hardness Tester. This study used independent t-test and paired sample t-test (p&lt;0.05).The result of this study showed that significant decrasing 0.000 (p&lt;0.05) of enamel hardness surface in average between before and after applied. …”
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Cystatin C as a Predictor of Mortality and Cardiovascular Events in a Population with Chronic Kidney Disease by Ana Vigil, Emilia Condés, Luis Vigil, Paloma Gallar, Aniana Oliet, Olimpia Ortega, Isabel Rodriguez, Milagros Ortiz, Juan Carlos Herrero, Carmen Mon, Gabriela Cobo, Juana Jimenez

“…Cardiovascular mortality was lower on the second than on the third cystatin C tertile (HR = 0.198; 95% CI: 0.040–0.987), but it did not show differences on the first and the second creatinine tertiles compared with the third one (HR = 0.126; 95% CI: 0.013–1.265 and HR = 0.403; 95% CI: 0.093–1.740). The only independent predictors of mortality during followup were baseline cystatin C (OR = 0.100; 95% CI: 0.021–0.463) and baseline uric acid (OR = 1.377; 95% CI: 1.070–1.773). …”
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Alternative Complement Pathway in Carotid Atherosclerosis: Low Plasma Properdin Levels Associate With Long‐Term Cardiovascular Mortality by Mieke C. Louwe, Chrysostomi Gialeli, Annika E. Michelsen, Sverre Holm, Andreas Edsfeldt, Karolina Skagen, Tove Lekva, Maria Belland Olsen, Vigdis Bjerkeli, Therese Schjørlien, Kristine Stø, Xiang Yi Kong, Tuva B. Dahl, Per H. Nilsson, Peter Libby, Pål Aukrust, Tom Eirik Mollnes, Thor Ueland, Mona Skjelland, Isabel Gonçalves, Bente Halvorsen

“…Conclusions We show a strong and independent association of low plasma properdin levels with cardiovascular mortality in 2 cohorts. …”
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Genome-wide association study unravels mechanisms of brain glymphatic activity by Shu-Yi Huang, Yi-Jun Ge, Peng Ren, Bang-Sheng Wu, Weikang Gong, Jing Du, Shi-Dong Chen, Ju-Jiao Kang, Qing Ma, Arun L. W. Bokde, Sylvane Desrivières, Hugh Garavan, Antoine Grigis, Herve Lemaitre, Michael N. Smolka, Sarah Hohmann, IMAGEN Consortium, Jian-Feng Feng, Ya-Ru Zhang, Wei Cheng, Jin-Tai Yu

“…Seven loci were replicated in two independent datasets. Genetic signals located at the 2p23.3 locus yielded significantly concordant effects in both young and aging cohorts. …”
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Exploring the relationship between sepsis and Golgi apparatus dysfunction: bioinformatics insights and diagnostic marker discovery by Wanli Ma, Xinyi Liu, Ran Yu, Jiannan Song, Lina Hou, Ying Guo, Hongwei Wu, Dandan Feng, Qi Zhou, Haibo Li

“…Validation with an independent dataset confirmed the differential expression patterns of B3GNT5, C1GALT1C1, and GALNT14, reinforcing their potential as robust diagnostic biomarkers for sepsis.ConclusionThis study elucidates the link between sepsis and the Golgi apparatus, introduces novel biomarkers for sepsis diagnosis, and offers valuable insights for future research on its pathogenesis and treatment strategies.…”
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Corticostriatal glutamate‐mediated dynamic therapeutic efficacy of electroacupuncture in a parkinsonian rat model by Xinxin Jiang, Min Sun, Yitong Yan, Yanhua Wang, Xinyu Fan, Jing Wei, Ke Wang, Peirong Liang, Zirui Wang, Jihan Wang, Xiaomin Wang, Jun Jia

“…Results Chronic EA stimulation resulted in a gradual and long‐lasting alleviation of motor symptoms, independent of nigrostriatal dopamine (DA) restoration. …”
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Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury by Kurt T. K. Giuliani, Purba Nag, Benjamin C. Adams, Xiangju Wang, Seokchan Hong, Anca Grivei, Rebecca L. Johnston, Nicola Waddell, Kenneth K. C. Ho, Yilin Tian, Muhammad Ali Khan, Chang Seong Kim, Monica S. Y. Ng, Glenda Gobe, Jacobus P. J. Ungerer, Josephine M. Forbes, Helen G. Healy, Andrew J. Kassianos

“…Abstract Hypoxia and interleukin (IL)-1β are independent mediators of tubulointerstitial fibrosis, the histological hallmark of chronic kidney disease (CKD). …”
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Stroke Outcome and Determinants among Patients with and without Diabetes in a Tertiary Hospital in Ghana by Josephine Akpalu, Alfred E. Yawson, Foster Osei-Poku, Yacoba Atiase, Ernest Yorke, Patrick Adjei, Kodwo Nkromah, Albert Akpalu

“…Diabetes mellitus, a well-established independent risk factor for stroke, has varied association with stroke outcome from previous studies. …”
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