The Clinical Value of the Combined Detection of Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Prognostic Nutritional Index (PNI) in Ear... by Zheng J, Zheng L, Wang X, Mao X, Wang Q, Yang Y, Mo D

“…Univariate and multivariate logistic regression analyses were utilized to verify independent risk factors for patients, and constructed the nomograms. …”
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Five-Year Predictors of Insulin Initiation in People with Type 2 Diabetes under Real-Life Conditions by Sandro Gentile, Felice Strollo, Francesca Viazzi, Giuseppina Russo, Pamela Piscitelli, Antonio Ceriello, Carlo Giorda, Piero Guida, Paola Fioretto, Roberto Pontremoli, Salvatore De Cosmo, the AMD-Annals Study Group

“…Multivariate analysis identified diabetes duration, HbA1c, triglyceride and low HDL-C values, presence of retinopathy or renal dysfunction, and sulphonylurea utilization (the risk being approximately 3 times greater in the latter case) as independent predictors of insulin treatment initiation. …”
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Predictors of Poor Outcome of Anti-MDA5-Associated Rapidly Progressive Interstitial Lung Disease in a Chinese Cohort with Dermatomyositis by Yuhui Li, Yimin Li, Jian Wu, Miao Miao, Xiaojuan Gao, Wenxin Cai, Miao Shao, Xuewu Zhang, Yan Xu, Lu Cong, Jing He, Xiaolin Sun

“…We identified older age and periungual erythema as two independent risk factors for RP-ILD mortality. Age≥57 years at disease onset was significantly associated with poor survival (P=0.02) in patients with anti-MDA5-associated RP-ILD, while patients with periungual erythema had a better survival rate than those without periungual erythema (P<0.05). …”
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Development of machine learning models for predicting non-remission in early RA highlights the robust predictive importance of the RAID score-evidence from the ARCTIC study by Gaoyang Li, Shrikant S. Kolan, Franco Grimolizzi, Joseph Sexton, Giulia Malachin, Guro Goll, Tore K. Kvien, Tore K. Kvien, Nina Paulshus Sundlisæter, Manuela Zucknick, Siri Lillegraven, Espen A. Haavardsholm, Espen A. Haavardsholm, Bjørn Steen Skålhegg

“…The model performance was evaluated through five independent unseen tests with nested 5-fold cross-validation. …”
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Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients by He Huang, Shilei Xu, Aidong Chen, Fen Li, Jiezhong Wu, Xusheng Tu, Kunpeng Hu

“…This five-mRNA classifier was an independent prognostic factor. Its predictive accuracy was also higher than all clinical factor models. …”
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Analysis of Risk Factors of Gastric Low-Grade Intraepithelial Neoplasia in Asymptomatic Subjects Undergoing Physical Examination by Yingling Liu, Yuli Cai, Si Chen, Yawen Gou, Qiaomin Wang, Mingli Zhang, Yetao Wang, Haiou Hong, Kaiguang Zhang

“…Risk factors including age, H. pylori infection, history of antibiotic misuse, and spicy and high-fat diet (all P<0.05) were further verified by multivariate analysis as independent risk factors. History of antibiotic misuse and H. pylori infection showed significant associations with LGIN (odds ratio OR=6.767, 95% confidence interval (CI) 3.873-11.825 and OR=3.803, 95% CI 3.009-4.808, respectively). …”
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Effect of older age and/or ACL injury on the dose–response relationship between ambulatory load magnitude and immediate load-induced change in serum cartilage oligomeric matrix pro... by Simon Herger, Corina Nüesch, Anna-Maria Liphardt, Christian Egloff, Annegret Mündermann

“…Also, ∆_sCOMP(tpost) was 19% lower in older than younger participants (p = 0.030) and increased with body mass index (p < 0.001), sCOMP(tpre) (p = 0.008), and with 120%BW (p < 0.001), independent of age, ACL injury, or sex. Conclusion: Age but not prior ACL injury influences resting sCOMP and load-induced sCOMP. …”
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PENGARUH PEMBELAJARAN DENGAN MODEL PROBLEM SOLVING FISIKA (PSF) TERHADAP PRESTASI BELAJAR DAN KEMAMPUAN BERPIKIR KRITIS by Mega Angellena, Eko Switoro, Desy Hanisa Putri

“…Data analysis which used the T-test two independent samples showed that 1) there was no significant effect of learning with the PSF learning model on the learning achievement with a value that was tcount<ttable (1.23 <2.00), with effect size of 0,31 which were in the low category. 2) there was a significant effect of learning with the PSF model on critical thinking skills known by the difference between the average Posttest score and average Pretest score (O2-O1) of 36,78, with effect size of 3,21, meant that the Problem Solving Fisika learning model had an effect of  98% and was in the High category. …”
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Hypercalcemia Following Adrenalectomy for Cushing Syndrome in a Patient with Post-Surgical Hypoparathyroidism by Pietro Locantore, Alessandro Oliva, Gianluca Cera, Rosa Maria Paragliola, Roberto Novizio, Caterina Policola, Andrea Corsello, Alfredo Pontecorvi

“…During her follow-up, an ACTH-independent Cushing syndrome was diagnosed, leading to a unilateral right adrenalectomy. …”
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Anemia and Contributing Factors in Severely Malnourished Infants and Children Aged between 0 and 59 Months Admitted to the Treatment Centers of the Amhara Region, Ethiopia: A Multi... by Wubet Worku Takele, Adhanom Gebreegziabher Baraki, Haileab Fekadu Wolde, Hanna Demelash Desyibelew, Behailu Tariku Derseh, Abel Fekadu Dadi, Eskedar Getie Mekonnen, Temesgen Yihunie Akalu

“…The binary logistic regression analysis was employed to show an association between the dependent and independent variables. Multicollinearity was assessed using the variance inflation factor (VIF) and no problem was detected (overall VIF = 1.67). …”
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Association Between Triglyceride–Glucose Index and Carotid Plaque Stability in Different Glycemic Status: A Single‐Center Retrospective Study by Guijun Huo, Jin Zheng, Junjie Cao, Lili Zhang, Zhichao Yao, Yuqi Zeng, Yao Tang, Zhanao Liu, Ziyi Tan, Dayong Zhou

“…The restrictive cubic spline analysis indicated a nonlinear relationship between the TyG index and unstable carotid plaque, with TyG index >8.63 identified as an independent risk factor for unstable carotid plaque. …”
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Preoperative White Blood Cell Count and Risk of 30-Day Readmission after Cardiac Surgery by Jeremiah R. Brown, R. Clive Landis, Kristine Chaisson, Cathy S. Ross, Lawrence J. Dacey, Richard A. Boss, Robert E. Helm, Susan R. Horton, Patricia Hofmaster, Cheryl Jones, Helen Desaulniers, Benjamin M. Westbrook, Dennis Duquette, Kelly LeBlond, Reed D. Quinn, Patrick C. Magnus, David J. Malenka, Anthony W. DiScipio

“…Patient readmission data was abstracted from each hospital. The independent association with preoperative WBC count was determined using logistic regression. …”
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Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infe... by Ying-ying Liang, Shuo Shao, Sichi Kuang, Jingbiao Chen, Jing Zhou, Bingjun He, Linqi Zhang, Yao Zhang, Kathryn J. Fowler, Jin Wang

“…HBV-negative (n = 39 patients, including 14 with hepatolithiasis and 25 with no identifiable risk factor for iCCA; none had cirrhosis). Two independent abdominal radiologists in consensus reviewed the largest mass in each patient to assign LI-RADS v2018 features; they also scored each observation’s shape and location. …”
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Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma by Jian‐Hua Wang, Shu‐Ting Huang, Lan Zhang, Zi‐Gang Liu, Rong‐Xin Liang, Sen‐Wei Jiang, Yi‐Nan Jiang, Xing‐Juan Yu, Yu‐Chuan Jiang, Xi‐Zhao Li, Pei‐Fen Zhang, Zhe‐Sheng Wen, Min Zheng

“…The combination of high CD47 and CD133 expression was a reliable independent prognostic factor for both OS (HR = 1.940, 95% CI = 1.399‐2.690, P < 0.0001) and progression‐free survival (HR = 1.883, 95% CI = 1.384‐2.562, P < 0.0001). …”
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Incidence and predictors of adverse birth outcomes among women who gave birth at Assosa general hospital, Northwest Ethiopia: a retrospective cohort study by Habtamu Tadesse Gudeta, Shalama Lekasa Nagari, Dessalegn Emana Jabana, Mustefa Aflegn Legese, Demekisa wondimu Biyena, Fantahun Cheklie Kassie

“…Statistically significant independent predictors of adverse birth outcomes were included fewer than 4 prenatal care visits (aRR = 3.53, 95% CI: 1.58, 5.37), malaria cases (aRR = 10.74, 95% CI: 6.56, 17.57), pregnancies with hypertensive disorders (aRR = 3.41, 95% CI: 2.17, 6.47), hemoglobin < 11 g/dl (aRR = 3.68, 95% CI: 2.42, 5.74), and a MUAC < 23 (aRR = 5.90, 95% CI: 3.98, 10.80). …”
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A New Risk Prediction Model for the Assessment of Myocardial Injury in Elderly Patients Undergoing Non-Elective Surgery by Vedat Cicek, Mert Babaoglu, Faysal Saylik, Samet Yavuz, Ahmet Furkan Mazlum, Mahmut Salih Genc, Hatice Altinisik, Mustafa Oguz, Berke Cenktug Korucu, Mert Ilker Hayiroglu, Tufan Cinar, Ulas Bagci

“…Multivariable analysis revealed that creatinine, lymphocyte, aortic regurgitation (moderate-severe), stroke, hemoglobin, ejection fraction, and D-dimer were independent determinants of MINS. By using these parameters, a model called “CLASHED” was developed to predict postoperative MINS. …”
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Potential pathogenic and protective genotypes and phenotypes of vitamin D binding protein in multiple sclerosis by Suhail Al-Shammri, Suhail Al-Shammri, Arpita Chattopadhyay, Abu Salim Mustafa

“…Differences between independent and related groups tested by Mann–Whitney U and Wilcoxon signed-rank tests respectively, Genotype and phenotype frequencies were calculated; p &lt; 0.05 considered significant.ResultsThe study detected four Gc genotypes/phenotypes, namely GC1F/Gc1F (c.1296T, c.1307C/p.432Asp, p.436Thr), GC1S/Gc1S (c.1296G, c.1307C/p.432Glu, p.436Thr), GC2/Gc2 (c.1296T, c.1307A/p.432Asp, p.436Lys), and GC3/Gc3 (c.1296G; c.1307A/p.432Glu, p.436Lys) in both subjects. …”
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Susceptibility profile and associated factors of urinary tract infections among women with established preterm labor delivering at a tertiary teaching hospital in Eastern Uganda: a... by Abdirizak Ahmed Ifrah, Marie Pascaline Sabine Ishimwe, Carlos Antonio Batista Cedeño, Eilu Emmanuel, Theoneste Hakizimana

“…Bivariate and multivariate analyses were used to determine association between the dependent and independent variables, with P < 0.05 as the level of significance at 95% confidence interval. …”
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Comparative Study on Associations Between Lung Cancer Prognosis and Diagnostic Criteria Set by the European Palliative Care Research Collaboration and the Asian Working Group for C... by Utae Katsushima, Takuya Fukushima, Jiro Nakano, Naoya Ogushi, Kazuki Fujii, Yutaro Nagata, Keisuke Kamisako, Yukiko Okuno, Yuta Okazaki, Kentaro Nakanishi, Kiyori Yoshida, Tatsuki Ikoma, Yuki Takeyasu, Yuta Yamanaka, Hiroshige Yoshioka, Kimitaka Hase, Takayasu Kurata

“…Conclusions Cachexia was an independent poor prognostic factor in lung cancer patients receiving chemotherapy under the AWGC and EPCRC criteria, both of which had similar prognostic discriminatory power. …”
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The incremental value of aspartate aminotransferase/alanine aminotransferase ratio combined with CURB-65 in predicting treatment outcomes in hospitalized adult community-acquired p... by Huamei Zhou, Xuelei Zhu, Yi Zhang, Wenjuan Xu, Shiqun Li

“…AST/ALT was also identified as an independent predictor of poor treatment outcome (OR = 3.672, 95% CI, 1.455–9.268, p = 0.006). …”
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