Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post‐operative dysfunction? by Márton Tokodi, Endre Németh, Bálint K. Lakatos, Erika Kispál, Zoltán Tősér, Levente Staub, Kristóf Rácz, Ádám Soltész, Szabolcs Szigeti, Tamás Varga, János Gál, Béla Merkely, Attila Kovács

“…Pre‐operative LEF was an independent predictor of post‐operative RVD defined as RVSWi < 300 mmHg⋅mL/m2 [OR = 1.33 (95% CI: 1.08–1.77), P < 0.05]. …”
Get full text

Insulin-Attenuated Inflammatory Response of Dendritic Cells in Diabetes by Regulating RAGE-PKCβ1-IRS1-NF-κB Signal Pathway: A Study on the Anti-Inflammatory Mechanism of Insulin in... by Liding Zhao, Ya Li, Qingbo Lv, Min Wang, Yi Luan, Jiale Song, Guosheng Fu, Junbo Ge, Yunzeng Zou, Wenbin Zhang

“…Insulin has the capability of attenuating the inflammatory response of DCs in diabetes, partly through the downregulation of RAGE expression followed by the inhibition of PKCβ1 phosphorylation and IRS1 serine phosphorylation, resulting in the inactivation of IR binding-independent NF-κB. This might partly explain the antiatherogenic effect of insulin on diabetes.…”
Get full text

Analysis of the relationship between environmental particulate matter exposure and congenital diseases, as well as the epidemiological trends and burden of impact on newborns by Mulati Julaiti, Dilixiati Wubuli, Tingting Cui, Nadire Nijiati, Pengfei Huang, Bowen Hu

“…Data from the UK Biobank and FinnGen databases were used to identify independent SNPs associated with environmental particulate. …”
Get full text

Cuproptosis-Related Signature Predicts the Prognosis, Tumor Microenvironment, and Drug Sensitivity of Hepatocellular Carcinoma by Xiangjun Qi, Jiayun Guo, Guoming Chen, Caishan Fang, Leihao Hu, Jing Li, Chi Zhang

“…Multivariate Cox regression analysis indicates that the signature is an independent prognostic factor. Pathways involved in metabolism and gene stability and immune infiltration cells are significantly enriched. …”
Get full text

Prognostic value of neutrophil-to-lymphocyte ratio dynamics in patients with septic acute kidney injury: a cohort study by Wei Wei, Caihong Liu, Guojiao Song, Letian Yang, Jian Li, Bo Wang, Ting Yin, Yingying Yang, Liang Ma, Ling Zhang, Ping Fu, Yuliang Zhao

“…After adjustment for potential confounders, high ΔNLR remained an independent predictor of 90-d mortality (HR = 2.80; 95% CI = 1.74–4.49, p < 0.001). …”
Get full text

Impact of Obstructive Sleep Apnea on In-Stent Restenosis in Coronary Heart Disease Patients after Elective Drug-Eluting Stenting by Wenjie Yang, Zhuoshan Huang, Ke Yang, Dinghui Liu, Junpeng Xiao, Zhen Wu, Ling Jiang, Shan Cao, Xujing Xie, Shujie Yu

“…Conclusions: In individuals who underwent elective drug-eluting stenting, OSA is an independent risk factor for ISR.…”
Get full text

The Effect of Blood-Derived Products on the Chondrogenic and Osteogenic Differentiation Potential of Adipose-Derived Mesenchymal Stem Cells Originated from Three Different Location... by Markus Neubauer, Olga Kuten, Christoph Stotter, Karina Kramer, Andrea De Luna, Thomas Muellner, Zsombor Lacza, Stefan Nehrer

“…Both PRP types had a different biological effect depending upon concentration, whereas hyperacute serum seemed to have a more consistent effect, independent of the used concentration. Conclusion. (i) Blood product preparation method, (ii) type of anticoagulant, (iii) differentiation time, and (iv) blood product concentration have a significant influence on stem cell viability and the differentiation potential, favouring no use of anticoagulation, shorter differentiation time, and lower blood product concentrations. …”
Get full text

Triglyceride-glucose index predicts adverse cardiovascular events in patients with H-type hypertension combined with coronary heart disease: a retrospective cohort study by Changjiang Li, Shun Zhao, Yingkai Li, Songyuan He, Wen Jian, Yanci Liu, Zichao Cheng, Hongyu Peng

“…Conclusion The TyG index may be an independent risk factor for predicting adverse postoperative cardiovascular events in patients with H-type hypertension combined with CHD, indicating its potential significance in improving risk stratification strategies. …”
Get full text

Optimalisasi Komunikasi dan Kolaborasi Humas untuk Peningkatan Tridharma di OTTIMMO Internasional by Baresa Margi Mukti, Merry Fridha Tripalupi, Teguh Priyo Sadono

“…Apart from being something that must be done, the Tridharma of higher education can provide benefits, namely producing graduates who are creative, innovative, independent and useful for the surrounding community. …”
Get full text

Protective factors, risk factors, and intervention strategies in the prevention and reduction of crime among adolescents and young adults aged 12-24 years: A scoping review protoco... by Rosanna Mary Rooney, Amber Hopkins, Jacob Peckover, Kael Coleman, Rebecca Sampson, Rosa Alati, Sharinaz Hassan, Christina M Pollard, Jaya A R Dantas, Roanna Lobo, Zakia Jeemi, Sharyn Burns, Robert Cunningham, Stephen Monterosso, Lynne Millar, Sender Dovchin, Rhonda Oliver, Ranila Bhoyroo, Getinet Ayano

“…Original research articles examining protective factors, risk factors, and intervention strategies for prevention and reduction of crime in 12-24-year-olds were included. Two independent reviewers conducted eligibility decisions and data extraction. …”
Get full text

PENGEMBANGAN MODUL SUHU DAN KALOR DENGAN PENDEKATAN SAINTIFIK UNTUK MELATIHKAN LITERASI SAINS PESERTA DIDIK DI SMA by Heni Fadilah, Dedy Hamdani, Andik Purwanto

“…This is an expert validation sheet that contains material aspects, aspects of module characteristics, language aspects and media aspects, while the module characteristics are developed, there is a scientific approach to the concepts and independent activity sheets, there are theoretical questions, calculation questions and scientific literacy questions to practice the ability of students. …”
Get full text

Game mechanics in eHealth interventions promoting self-management in young people with chronic diseases: a protocol for a systematic review and meta-analyses from the eHealth Junio... by Sanne L Nijhof, Elise van de Putte, Fernando Estévez-López, Wichor M Bramer, Lisa Levelt, Job van ’t Veer, Micah M Hrehovcsik, Valentijn Visch, Manon H. J. Hillegers, Remco C Veltkamp

“…Primary quantitative, qualitative or mixed-method studies written in English will be included. Two independent reviewers will (1) select studies, (2) extract and summarise the implemented game mechanics as well as the characteristics of the intervention and study, (3) evaluate their methodological quality and (4) synthesise the evidence. …”
Get full text

Power of emperor in Russian legal discourse of second half of 19th– early 20th centuries: justification and options for interpretation by I. G. Adoneva, Yu. V. Druzhinina

“…Without disputing the content of the «Fundamental State Laws» and guided by censorship considerations, the professors tried to convey to the student university audience the idea that the bureaucratic apparatus formed in the empire is a natural limiter of the imperial power; the legal framework is an obstacle to despotism, and the judiciary is in fact independent. This kind of theoretical constructs became a compromise between the preservation of absolute monarchical power and the worldview of those jurists who shared liberal values…”
Get full text

Prognostic value of tumor‐infiltrating lymphocytes and PD‐L1 expression in esophageal squamous cell carcinoma by Jie Hu, Takeshi Toyozumi, Kentaro Murakami, Satoshi Endo, Yasunori Matsumoto, Ryota Otsuka, Tadashi Shiraishi, Shinichiro Iida, Hiroki Morishita, Tenshi Makiyama, Yuri Nishioka, Masaya Uesato, Koichi Hayano, Akira Nakano, Hisahiro Matsubara

“…Conclusion Tumor depth, CD8, and PD‐L1 TC were independent prognostic factors in ESCC, and a predictive nomogram with these three risk factors improved the accuracy of predicting OS in patients with ESCC after surgical resection. …”
Get full text

7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan by Sung-Shuo Kao, Wen-Chi Chen, Ping-I Hsu, Kwok-Hung Lai, Hsien-Chung Yu, Hui-Hwa Cheng, Nan-Jing Peng, Chiun-Ku Lin, Hoi-Hung Chan, Wei-Lun Tsai, Huay-Min Wang, Tzung-Jiun Tsai, Kung-Hung Lin, Feng-Woei Tsay

“…Multivariate analysis disclosed that poor compliance was the only independent factor influencing the efficacy of anti-H. pylori therapy with an odds ratio of 0.073 (95% confidence interval, 0.011–0.483). …”
Get full text

Integrin α8 is a useful cell surface marker of alveolar lipofibroblasts by Atsuki Fukada, Yasunori Enomoto, Ryo Horiguchi, Yoichiro Aoshima, Shiori Meguro, Hideya Kawasaki, Isao Kosugi, Tomoyuki Fujisawa, Noriyuki Enomoto, Naoki Inui, Takafumi Suda, Toshihide Iwashita

“…The transcriptome profile of ITGA8+ fibroblasts in adult mouse lungs, evaluated through two independent single-cell RNA-seq datasets, consistently showed higher expression of Tcf21 and Plin2, which are canonical markers of lipofibroblasts. …”
Get full text

Digital Health Technology Interventions for Improving Medication Safety: Systematic Review of Economic Evaluations by Widya Norma Insani, Neily Zakiyah, Irma Melyani Puspitasari, Muhammad Yorga Permana, Kankan Parmikanti, Endang Rusyaman, Auliya Abdurrohim Suwantika

“…The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed for this systematic review. Two independent investigators conducted a full-text review after screening preliminary titles and abstracts. …”
Get full text

Evaluation of Endoscopic Ultrasound Image Quality Is Necessary in Endosonographic Assessment of Early Gastric Cancer Invasion Depth by Shunsuke Yamamoto, Tsutomu Nishida, Motohiko Kato, Takuya Inoue, Yoshito Hayashi, Jumpei Kondo, Tomofumi Akasaka, Takuya Yamada, Shinichiro Shinzaki, Hideki Iijima, Masahiko Tsujii, Tetsuo Takehara

“…Low-quality EUS images led to an incorrect diagnosis of invasion depth of EGC, independent of tumor location or size.…”
Get full text

The relationship between activities of daily living and speech impediments based on evidence from statistical and machine learning analyses by Liu Jun, Hongguo Li, Yu Mao, Lan Hu, Dan Wu

“…Statistical analyses, including independent sample t-tests, chi-square tests, Pearson and Spearman correlation tests, and hierarchical multiple linear regression, were conducted using SPSS 25.0. …”
Get full text

Efforts to strengthen anatomic pathology diagnostic services for cancer in sub-Saharan Africa: a scoping review protocol by Katherine Van Loon, Elia John Mmbaga, Marcia Edelweiss, Dianna L. Ng, Asteria Herman Kimambo, Edda Vuhahula, Beatrice Paul Mushi, Omolade Adegoke, Johanna Goldberg, Pendo M. Ibrahim, Zainab Illonga, Julia Jackman, Luisa Jamisse

“…A limited search for grey literature will be conducted using the WHO Institutional Repository for Information Sharing. Two independent reviewers will screen all articles, extract data and complete the descriptive analysis. …”
Get full text