Stem cell-derived exosome treatment for acute spinal cord injury: a systematic review and meta-analysis based on preclinical evidence by Chunlin Mou, Ziyao Xia, Ziyao Xia, Ziyao Xia, Xiujuan Wang, Xunan Dai, Jiaxian Wang, Chun Zhang, Chun Zhang, Yongsheng Xu, Yongsheng Xu, Yongsheng Xu

“…BackgroundThe study aims were to systematically review and analyze preclinical research on the efficacy of exosomes derived from various mesenchymal stem cell sources (MSC-exos) for the treatment of spinal cord contusion injury (SCI) in small animal models.MethodsWe conducted a systematic search of PubMed, Embase and Google Scholar databases from their inception through February 29, 2024, to identify eligible English-language studies based on predefined inclusion and exclusion criteria. Two independent investigators performed literature screening, data extraction and bias assessment.ResultsA total of 235 rats were used to assess locomotor recovery at the initial assessment, and exhibited significant improvement in hind limb movement in those treated with exosomes, as indicated by a statistically significant increase in Basso-Beattie-Bresnahan (BBB) scores (MD: 1.26, 95% CI: 1.14–1.38, p < 0.01) compared to the controls. …”
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Brazilian Gold Miners Working Irregularly in French Guiana: Health Status and Risk Determinants by Amanda Figueira da Silva, Vivian da Cruz Franco, Maylis Douine, Hermano Gomes Albuquerque, Louise Hureau, Alice Sanna, Pamela Mosquera Atehortua, Rafael dos Santos Pereira, Simone da Silva Santos, Paola Barbosa Marchesini, Gustavo Bretas, Margarete do Socorro Mendonça Gomes, Yann Lambert, Martha Cecília Suárez-Mutis

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How have interventions targeting pregnant women from refugee, migrant and culturally and linguistically diverse backgrounds living in high-income countries been developed or tailor... by Sweekriti Sharma, Gayathri Jegadeesh, Camille Raynes-Greenow, Adrienne Gordon, Gayani Gunawardhana, Danielle Marie Muscat

“…We included studies that report on the development and/or evaluation of a program or intervention to reduce the risk of stillbirth which has been specifically developed or tailored for pregnant women from culturally and linguistically diverse backgrounds living in high-income countries. Two independent reviewers conducted screening of the articles, data extraction, and quality appraisal. …”
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Clinical Impact of Prophylactic Antibiotic Treatment for Self-Expandable Metallic Stent Insertion in Patients with Malignant Colorectal Obstruction by Jong-Sun Kim, Wan-Sik Lee, Cho-Yun Chung, Hyung-Chul Park, Dae-Seong Myung, Chan-Young Oak, Mi-Young Kim, Mi-Ok Jang, Seung-Ji Kang, Hee-Chang Jang, Sung-Bum Cho, Hyun-Soo Kim, Young-Eun Joo

“…However, in propensity score matching analysis, there was no independent risk factor related to post-SEMS insertion fever, SIRS, and bacteremia. …”
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Pengaruh Gangguan Tidur Terhadap Kadar Hormon Testosteron dan Jumlah Spermatozoa pada Tikus Jantan Wistar by Leni Tri Wahyuni, Adnil Edwin Nurdin, Eliza Anas

“…Sleeping disturbance was an independent variable, while<br />the quality of sperm testosterone hormone and the number of sperm were dependent variables. …”
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Risk factors for moderate disturbance of consciousness in patients with unilateral chronic subdural hematoma by Adrian Liebert, Thomas Eibl, Thomas Bertsch, Hans-Herbert Steiner, Karl-Michael Schebesch, Leonard Ritter

“…Among those are greater midline shift, occipital location and history of ischemic stroke as independent risk factors.…”
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Prevalence and health consequences of nonmedical use of tramadol in Africa: A systematic scoping review. by Saidou Sabi Boun, Olumuyiwa Omonaiye, Sanni Yaya, Sanni Yaya

“…The articles were imported into Covidence and reviewed by two independent researchers. Eighty-three studies on NMU of tramadol's prevalence or health consequences were selected from 532 titles/abstracts screened, including 60 cross-sectional and six qualitative studies from 10 African countries. …”
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What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review by Benedict Hayhoe, Azeem Majeed, Geva Greenfield, Ana Luísa Neves, Henock B Taddese, Kalthum Patail, Hui Hsuan Pai

“…The study was reported following the best practice guidelines defined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Data sources We searched for articles published from January 2007 to December 2023 via MEDLINE (Ovid), Embase (Elsevier), CINAHL (Ovid) and Scopus (Elsevier).Eligibility criteria Primary qualitative studies that describe the perceptions and experiences of adults in using mobile applications in self-management of types 1, 2 and gestational diabetes published between January 2007 and December 2023.Data extraction and synthesis Two independent reviewers screened identified papers for eligibility, extracted data using a pre-defined data extraction form and applied the Critical Appraisal Skills Program tool to appraise the quality of the included studies. …”
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Prediction of the risk of 3-year chronic kidney disease among elderly people: a community-based cohort study by Tao Wang, Zhitong Zhou, Longbing Ren, Zhiping Shen, Jue Li, Lijuan Zhang

“…Logistic regression analysis was used to determine the independent predictors. A nomogram was established to predict the occurrence of CKD within 3 years. …”
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Anti-microbial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase by Bright Obeng, Lucas J. Bennett, Bailey E. West, Dylan J. Wagner, Patrick J. Fleming, Morgan N. Tasker, Madeleine K. Lorenger, Dorothy R. Smith, Tetiana Systuk, Sydni M. Plummer, Jeongwon Eom, Marissa D. Paine, Collin T. Frangos, Michael P. Wilczek, Juyoung K. Shim, Melissa S. Maginnis, Julie A. Gosse

“…The inhibitory effect of CPC was independent of signaling platform receptor architecture. …”
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Is platelet-rich plasma better than steroids as epidural drug of choice in lumbar disc disease with radiculopathy? Meta-analysis of randomized controlled trials by Sathish Muthu, Sathish Muthu, Sathish Muthu, Vibhu Krishnan Viswanathan, Vibhu Krishnan Viswanathan, Prakash Gangadaran, Prakash Gangadaran, Prakash Gangadaran

“…The current meta-analysis was performed to analyze the efficacy and safety of platelet-rich plasma (PRP) as an epidural injectate, in comparison with steroids in the management of radiculopathy due to lumbar disc disease (LDD). We conducted independent and duplicate searches of the electronic databases (PubMed, Embase and Cochrane Library) in March 2024 to identify randomized controlled trials (RCTs) analyzing the efficacy of epidural PRP for pain relief in the management of LDD. …”
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Effects of the maternal and child health handbook and other home-based records on mothers’ non-health outcomes: a systematic review by Akira Shibanuma, Masamine Jimba, Rogie Royce Carandang, Jennifer Lisa Sakamoto, Ekaterina Yarotskaya, Milana Basargina, Mika Kondo Kunieda

“…Objective This review aimed to investigate the effects of the maternal and child health (MCH) handbook and other home-based records on mothers’ non-health outcomes.Design Systematic review.Data sources PubMed, Web of Science, CINAHL, Academic Search Complete, PsycArticles, PsycINFO, SocINDEX, CENTRAL, NHS EED, HTA, DARE, Ichuushi and J-STAGE through 26 March 2022.Eligibility criteria for selecting studies Original research articles examining home-based records and mothers’ non-health outcomes published in English or Japanese across various study designs.Data extraction and synthesis Two independent reviewers extracted relevant data and assessed the risk of bias. …”
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Association of intratumoral microbiome diversity with hepatocellular carcinoma prognosis by Fengle Jiang, Yuan Dang, Zheting Zhang, Yanan Yan, Yingchao Wang, Yi Chen, Lihong Chen, Jialiang Zhang, Jingfeng Liu, Jianmin Wang

“…Notably, specific taxa could independently predict HCC prognosis. Based on these findings, intratumoral microbiomes facilitate the use of precision medicine in clinical practice.…”
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A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer by Chenxi Lv, Tianwei Chen, Jiangtao Li, Yuqiang Shan, Hong Zhou

“…The HTTR signature emerged as an independent prognostic factor, effectively stratifying patients into low- and high-risk groups with significant differences in overall survival. …”
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Real world study on combining local interventions with systemic therapy in unresectable hepatocellular carcinoma by Zhaosong Xue, Ming Yao, Kang Chen, Taiyun Huang, Jianjun Li, Jian Chen, Fei Huang, Yubin Huang, Xiaoyong Cai, Yihe Yan

“…Importantly, hepatectomy independently associated with a favorable overall survival (HR, 0.388; 95% CI, 0.177–0.847; P = 0.017). …”
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Neonatal near Miss and Its Predictors among Neonates Delivered at Debretabor General Hospital, Northern Ethiopia; A Retrospective Analysis by Habtamu Abie Tassew, Fisseha Yetwale Kassie, Muhabaw Shumye Mihret

“…Rural residence (AOR=4.41; 95% CI: 2.57,7.55), incomplete ANC visit (AOR=3.16; 95% CI: 1.90,5.25), primiparous (AOR=2.55; 95% CI: 1.59,4.12), pregnancy-induced hypertension (AOR=3.23; 95% CI: 1.19,8.78), premature rupture of membrane (AOR=4.65; 95% CI: 1.70,12,73), cephalic-pelvic disproportion (AOR=3.05; 95% CI: 1.32,7.01), and antepartum hemorrhage (AOR=4.95; 95% CI: 1.89,12.96) were the independent predictors of neonatal near-miss. Conclusion and Recommendations. …”
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Traditional Cardiovascular Risk Factors Associated with Diagonal Earlobe Crease (Frank Sign) in Mexican Adults: Aging, Obesity, Arterial Hypertension, and Being Male Are the Most I... by Rogelio Molina-Gallardo, Nomely S. Aurelien-Cabezas, Daniel Tiburcio-Jimenez, Jorge E. Plata-Florenzano, Jose Guzman-Esquivel, Iram P. Rodriguez-Sanchez, Margarita L. Martinez-Fierro, Roque Molina-Osorio, Adrian A. De-la-Madrid-Cernas, Jorge Armando Barriguete-Melendez, Ivan Delgado-Enciso

“…The multivariate analysis showed that men (OR 1.6, 95% IC 1.1–2.4, P=0.007), being over 55 years old (OR 4.8, 95% IC 3.2–7.2, P<0.001), being obese (OR 2.1, 95% IC 1.4–3.1, P<0.001), having arterial hypertension (1.5, 95% IC 1.1–2.3, P=0.025), or suffering from acute coronary syndrome (OR 5.3, 95% IC 2.5–11.1, P<0.001), were independent factors associated with diagonal earlobe crease. …”
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Productive performance of buffaloes (Bubalus bubalis) in two production systems and two slaughter weights by René Rodríguez-Florentino, David Hernández-Sánchez, Efrén Ramírez-Bribiesca, María M. Crosby Galván, Miguel Á. Mata-Espinosa, Luis A. de la Cruz-Cruz

“…Analysis of variance was conducted (PROC GLM; SAS®), considering weight and daily weight gain and fattening period as dependent variables and treatments as independent variables. When numerical differences were detected, a multiple comparison Tukey test was utilized (p<0.05). …”
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Habits Related to Strength Training of Brazilian Recreational Runners by Wagner K. A. Santos, Lucas D. M. Forte, Alexandre S. Silva, Hallisson V. de O. Rufino, Lucas de F. Vieira, João M. F. Lima Silva, Mabliny Thuany, Reginaldo Gonçalves, Ytalo M. Soares

“…To assess the possible associations between categorical variables, data were analyzed using the chi-square test for independent samples. Approximately 625 runners (78.1%) reported that they included ST in their training routine, with a statistically significant difference between the sexes (men: 73.5% vs. women: 85.4%; X² = 14.09; <i>p</i> = 0.01). …”
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Development of a machine learning model related to explore the association between heavy metal exposure and alveolar bone loss among US adults utilizing SHAP: a study based on NHAN... by Jiayi Chen

“…The relationship of Co & Pb and ABL are weaker than that of Cd. Among all the independent variables, age was considered the most important factor for this model. …”
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