msiFlow: automated workflows for reproducible and scalable multimodal mass spectrometry imaging and microscopy data analysis by Philippa Spangenberg, Sebastian Bessler, Lars Widera, Jenny Bottek, Mathis Richter, Stephanie Thiebes, Devon Siemes, Sascha D. Krauß, Lukasz G. Migas, Siva Swapna Kasarla, Prasad Phapale, Jens Kleesiek, Dagmar Führer, Lars C. Moeller, Heike Heuer, Raf Van de Plas, Matthias Gunzer, Oliver Soehnlein, Jens Soltwisch, Olga Shevchuk, Klaus Dreisewerd, Daniel R. Engel

“…Here, we present msiFlow, an accessible open-source, platform-independent and vendor-neutral software for end-to-end, high-throughput, transparent and reproducible analysis of multimodal imaging data. msiFlow integrates all necessary steps from raw data import to analytical visualisation along with state-of-the-art and self-developed algorithms into automated workflows. …”
Get full text

Development and validation of the “Adjustment Disorder Scale for Medically Ill Patients - ETAM” by Juan Pablo Zapata-Ospina, Natalia Rodríguez, Ayda Margarita Rodríguez, Jenny García-Valencia, Mercedes Jiménez-Benítez, Nicolás Martínez-Ramos, Diana Restrepo Bernal, Ana Lucía Gallego, Carolina Gómez, Luis Fernando Tabares, Carlos Cardeño-Castro, Daniel Camilo Aguirre-Acevedo

“…Criterion validity evidence was obtained with an independent psychiatrist’s diagnosis, with an AUROC of 0.99, and convergent validity was consistent with hypotheses of correlation with other instruments with similar constructs. …”
Get full text

Predictive value of the monocyte count for determining the risk of postoperative moderate-to-severe ARDS in patients undergoing one-lung ventilation during radical treatment of eso... by Feng Zhang, Feng Zhang, Shunmei Lu, Guilong Wang, Hongyang Xu, Dongxiao Huang, Xiaomin Li

“…Regression analysis revealed that postoperative monocyte count was an independent predictor for severe ARDS after surgery (OR = 2.916, 95% CI: 1.082–7.863, p < 0.05). …”
Get full text

Poly-Systemic Analysis of Military Students’ Discipline by L. Ya. Dorfman, A. V. Dubrovsky, A. P. Andrunik, E. A. Tsariev, V. N. Lyadov

“…Three models were tested: a unitary model (without allocation of discipline systems), a dual parallel model (with independent systems of social discipline and self-discipline) and a dual overlapping model (composite). …”
Get full text

Pengaruh Metode Pembelajaran Problem Based Learning yang Diperkaya dengan ARCS Motivational Model terhadap Kualitas Manajemen Kelas dan Motivasi Belajar Siswa secara Online pada Ma... by Allisa Majid, Admaja Dwi Herlambang, Faizatul Amalia

“…Then, a Likert-scaled questionnaire was distributed, the results of which were calculated using the percentage index (%), normality test of the data using Kolmogorov Smirnov, and hypothesis testing using the independent t-test. The results of this study found that the application of the Problem Based Learning method and the ARCS Motivational Model had an effect on the quality of classroom management and student learning motivation. …”
Get full text

An Upper Bound for Locating Strings with High Probability Within Consecutive Bits of Pi by Víctor Manuel Silva-García, Manuel Alejandro Cardona-López, Rolando Flores-Carapia

“…To support the hypotheses, we present experimental evidence about the equiprobable and independent properties of bits of <inline-formula><math display="inline"><semantics><mi>π</mi></semantics></math></inline-formula>, analyzing their distribution, and measuring correlations between bit strings. …”
Get full text

Newborn Care Practice and Associated Factors among Mothers of One-Month-Old Infants in Southwest Ethiopia by Amanuel Nuramo Sakelo, Nega Assefa, Lemessa Oljira, Zebene Mekonnen Assefa

“…Education level, health education (counseling) on hygiene, and knowledge of mother on newborn care practice were independent predictors of newborn care practice.…”
Get full text

Relationship Between Serum HMGB1 and RAGE Levels and Restenosis in Type 2 Diabetes Mellitus Patients Complicated With Lower Extremity Vascular Disease: A Retrospective Study by Jia T, Zhang X, Li L, Jiang X, Wang M

“…Multivariate logistic regression analysis revealed that HMGB1 and RAGE were independent risk factors for restenosis in T2DM patients with lower extremity vascular disease undergoing interventional therapy. …”
Get full text

Identification of Five m6A-Related lncRNA Genes as Prognostic Markers for Endometrial Cancer Based on TCGA Database by Li Shan, Ye Lu, Cheng-Cheng Xiang, Xiaoli Zhu, Er-Dong Zuo, Xu Cheng

“…The risk score was also verified as an independent prognostic indicator for UCEC and was related to immune cell infiltration levels. …”
Get full text

Unraveling the laser decal transfer-based printing of ZnO ceramic towards FEP-ZnO-based Piezo-Tribo hybrid nanogenerators by Arpit Kumar Singh, Anshu Sahu, Palani Iyamperumal Anand

“…With advancements in technologies, a thin film-based laser decal transfer setup is yet to be fully explored for printing thin-film materials in pixelated form over substrates, enabling substrate- and material-independent processes.The present work focuses on the development of a laser decal transfer-based printing process using thin film as feed material for the fabrication of MEMS devices for piezo-tribo hybrid applications. …”
Get full text

Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia by Fei Xie, Ting-juan Zhang, Xin-long Zhang, Zi-jun Xu, Liang Qiao, Yun Wang, Yang-jing Zhao, Jun Qian, Jing-dong Zhou

“…Afterwards, the candidate prognosis-related gene HOXA9 were selected for clinical relevance analysis and were further validated in another independent cohort from our research center. Results The methylation of HOXA9, among HOXA cluster genes, negatively correlated with adverse prognosis and expression were screened and identified in AML among TCGA datasets. …”
Get full text

The U-Shaped Association between Bilirubin and Diabetic Retinopathy Risk: A Five-Year Cohort Based on 5323 Male Diabetic Patients by Miao Liu, Jianhua Wang, Yao He

“…Serum TBiL had a U-shaped relationship with DR incidence, which was independent of control status of diabetes and other related covariates.…”
Get full text

Optimization and calibration of 384-well kinetic Ca2+ mobilization assays for the human transient receptor potential cation channels TRPM8, TRPV1, and TRPA1 by David A. Close, V. Blair Journigan, Paul A. Johnston

“…EC50 and IC50 values of TRPM8 agonists and antagonists determined in single experiments were strongly aligned to those from multiple independent experiments. Benchmark TRPM8, TRPV1, and TRPA1 EC50 and IC50 values were within the ranges previously reported for agonist and antagonist standards. …”
Get full text

Understanding crystallinity indexes benchmarking concept from optimized parametric ionic liquid pretreatment using 1-ethyl-3-methylimidazolium Acetate [EMIM]Ac on oil palm biomass by Amizon Azizan, Rosmaria Abu Darim, Intan Suhada Azmi, Rafidah Jalil, Shareena Fairuz Abdul Manaf

“…All the linear model terms of these independent variables, along with the 2-way interaction model between the ionic liquid and solid loading, were found to be significant to the effect of CrI on the pretreated OPF. …”
Get full text

Repetitive Mild but Not Single Moderate Brain Trauma Is Associated with TAR DNA-Binding Protein 43 Mislocalization and Glial Activation in the Mouse Spinal Cord by Tamara Janković, Jelena Rajič Bumber, Nika Gržeta Krpan, Petra Dolenec, Marc Jaeger, Jasna Kriz, Gordana Župan, Kristina Pilipović

Get full text

Maternal singing and speech have beneficial effects on preterm infant’s general movements at term equivalent age and at 3 months: an RCT by Manuela Filippa, Gianluca Filippa, Elisa Della Casa, Alberto Berardi, Odoardo Picciolini, Sara Chiara Meloni, Clara Lunardi, Alessandra Cecchi, Alessandra Sansavini, Luigi Corvaglia, Luigi Corvaglia, Didier Grandjean, EVC Group, Fabrizio Ferrari

Get full text

Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy by Shi Chen, Li-Ying Ou-Yang, Run-Cong Nie, Yuan-Fang Li, Jun Xiang, Zhi-Wei Zhou, Ying-Bo Chen, Jun-Sheng Peng

“…Multivariate analysis revealed that postoperative chemotherapy and pathological T stage were independent prognostic factors. Conclusion. Our results imply that tumor size should be a critical factor in the decision to utilize adjuvant chemotherapy for T3-4aN0M0 gastric cancer patients after D2 gastrectomy. …”
Get full text

Wealth-based inequality in underweight among Scheduled Tribe women in India: a regional analysis by Anshika Singh, Aditya Singh, Mahashweta Chakrabarty, Shivani Singh, Pooja Tripathi

Get full text

Validation of a B-type natriuretic peptide as a prognostic marker in pneumonia patients: a prospective cohort study by Yu Hashimoto, Daisuke Usuda, Ryusho Sangen, Emiri Muranaka, Yoshitsugu Iinuma, Tsugiyasu Kanda

“…In multivariable Cox-regression analysis, BNP remained an independent mortality predictor (HR 10.01, 95% CI 1.32 to 75.7, p=0.03) in CAP.Conclusions BNP levels may be a useful single prognostic marker for CAP. …”
Get full text

Externally validated nomogram for predicting short-term pregnancy outcome of singleton pregnancies with fetal growth restriction (FGR) by Yang Li, Xiaohong Zhang, Junshu Xie, Fufen Yin, Mingrui Jin, Yujing Li, Xiuju Yin

“…External validation was performed in 321 eligible singleton FGR pregnancies at the Affiliated Hospital of Qingdao University.Results Absent umbilical arterial flow, fetal anomaly, history of abnormal pregnancy, non-cephalic presentation and history of caesarean section were independent prognostic factors for adverse perinatal outcomes in singleton FGR pregnancies in the training set. …”
Get full text