The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment by Yanchao Luan, Chao Liang, Qingsong Han, Xueqin Zhou, Na Yang, li Zhao

“…Cox regression analysis determined that the pathological T stage, tumor stage, and RiskScore could serve as independent prognostic indicators. Analysis of the abundance of 22 immune infiltrating cells revealed that 15 immune cell types exhibited substantial differences and were strongly associated with risk ratings and prognosis. …”
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Features of the use of physical exercises at the long-term stage of rehabilitation after intra-articular fractures by Sviatoslava Pashkevych, Tetiana Shutieieva, Оlha Beziazychna

“…Nonparametric statistics were used to determine differences between groups, Wilcoxon test for related sets, and Mann-Whitney criteria for independent sets. Values ​​of p <0.05 were considered significant. …”
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The Relationship Between the Modified Glasgow Prognostic and SYNTAX Scores in Patients with Non-ST Elevation Myocardial Infarction by Ahmet KARADUMAN, Cemalettin YILMAZ, Mustafa Ferhat KETEN, Ismail BALABAN, Zeynep Esra GUNER, Mehmet CELIK

“…Smoking [odds ratio (OR): 3.341, 95% confidence interval (CI): 1.531-7.294; p=0.002], CRP/albumin ratio (OR: 4.958, 95% CI: 1.335-18.418; p=0.017), and mGPS score of 1-2 (OR: 3.121, 95% CI: 1.430-6.814; p=0.004) were independent factors used to help predict a high SYNTAX score. …”
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Effect of PCSK9 Inhibitor on Blood Lipid Levels in Patients with High and Very-High CVD Risk: A Systematic Review and Meta-Analysis by Yue Zhang, Yanrong Suo, Lin Yang, Xiaolu Zhang, Qun Yu, Miao Zeng, Wenlan Zhang, Xijuan Jiang, Yijing Wang

“…The data quality of included studies was assessed by two independent researchers using the Cochrane systematic review method. …”
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Clinicopathological Features, Treatment Strategy, and Prognosis of Primary Non-Hodgkin’s Lymphoma of the Duodenum: A SEER Database Analysis by Guoliang Zheng, Yue Wang, Yan Zhao, Zhichao Zheng

“…Age, gender, Ann Arbor staging, and histological type were regarded as independent prognostic factor for the DSS by multivariate analysis (all P<0.05). …”
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Prognostic factors for head and neck cancer of unknown primary including the impact of human papilloma virus infection by Lars Axelsson, Jan Nyman, Hedda Haugen-Cange, Mogens Bove, Leif Johansson, Shahin De Lara, Anikó Kovács, Eva Hammerlid

“…HPV infection was common. Independent prognostic factors for survival were age over 70 years, HPV status and N3 stage. …”
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The Association between Antihypertensive Medication Use and Blood Pressure Is Influenced by Obesity by Jash S. Parikh, Arshdeep K. Randhawa, Sean Wharton, Heather Edgell, Jennifer L. Kuk

“…We examined whether BP attained when using various antihypertensive medications varies amongst different body mass index (BMI) categories and whether antihypertensive medication use is associated with differences in other metabolic risk factors, independent of BMI. Methods. Adults with hypertension from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2014 were used (n=15,285). …”
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From Polydeoxyribonucleotides (PDRNs) to Polynucleotides (PNs): Bridging the Gap Between Scientific Definitions, Molecular Insights, and Clinical Applications of Multifunctional Bi... by Cíntia Marques, Alexandre Porcello, Marco Cerrano, Farid Hadjab, Michèle Chemali, Kelly Lourenço, Basste Hadjab, Wassim Raffoul, Lee Ann Applegate, Alexis E. Laurent

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Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera by Sadegh Ghafarian, Ahmad Masoumi, Seyed Ali Tabatabaei, Mehdi Yaseri, Eisuke Shimizu, Shintaro Nakayama, Rohan Jeetendra Khemlani, Hiroki Nishimura, Hassan Asadigandomani

“…Both SEC videos and slit-lamp photos were reported by two independent ophthalmologists and compared with a slit-lamp examination as a gold standard. …”
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Incidence and Risk Factors of Diabetic Foot Ulcer: A Population-Based Diabetic Foot Cohort (ADFC Study)—Two-Year Follow-Up Study by Leila Yazdanpanah, Hajieh Shahbazian, Iraj Nazari, Hamid Reza Arti, Fatemeh Ahmadi, Seyed Ehsan Mohammadianinejad, Bahman Cheraghian, Saeed Hesam

“…Our data showed that the average annual DFU incidence is about 2.8%. Independent risk factors of DFU development were previous history of DFU or amputation, insulin consumption, gender, distal neuropathy, and foot deformity. …”
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Suboptimal Blood Pressure Control, Associated Factors, and Choice of Antihypertensive Drugs among Type 2 Diabetic Patients at KCMC, Tanzania by Gabriel W. Mbwete, Kajiru G. Kilonzo, Elichilia R. Shao, Nyasatu G. Chamba

“…Chi-square analysis was done to identify the independent predictors of BP control, and a p value of <0.05 was considered to be statistically significant. …”
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Toxicity evaluation of herbicides used in sugarcane crops to Zebrafish (Danio rerio) by Gabrielli Aparecida Sanches Tesolin, Marina Menezes Marson, Claudio Martín Jonsson, António José Arsénia Nogueira, Daniel Andrade de Siqueira Franco, Sydnei Dionísio Batista de Almeida, Marcus Barifouse Matallo, Monica Accaui Marcondes de Moura

“…The mixture model that best describes the relationship between the two components is independent action and toxicity of the mixture is dose-dependent, occurring antagonism at low doses and synergism at high doses. …”
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Factors Influencing the Demoralisation Syndrome of Post‐Operative Patients With Breast Cancer: A Cross‐Sectional Study by Yuxin Huang, Panpan Zhuang, Aixuan Guan, Xiu Rong Ren, Lichun Xu

“…Multivariate analysis revealed that income, cancer stage, recurrence, quality of recovery index (QRI) and BIS were independent influencing factors for demoralisation syndrome after breast cancer surgery. …”
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Adaptation Studies of the Aggression and Victimization Scales for Elementary School Children by Arzu KURNAZ, Emine Gül KAPÇI

“…T-test analysesfor independent groups demonstrated that boys had higher mean scores for overt aggression than girls (t(423)=3.025,p<.05). …”
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Complete mitochondrial genome sequence analysis revealed double matrilineal components in Indian Ghoongroo pigs by Pranab Jyoti Das, Satish Kumar, Manasee Choudhury, Seema Rani Pegu, K. Meera, Rajib Deb, Sunil Kumar, Santanu Banik, Vivek Kumar Gupta

“…Phylogenetic analysis demonstrated a clear clustering of GH sequences into two clades, indicating the presence of two independent maternal lineages. The phylogenetic study using complete mitogenome also indicated that GH pigs were originated locally from Indian wild boar independently from Asian and European pig population. …”
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Multifocality and Detectability of Prostate Cancer with 3-Tesla Multiparametric Magnetic Resonance Imaging: Correlation with Radical Prostatectomy Mapping Histopathology by Serdar Karadağ, Deniz Noyan Özlü, Ahmet Hacıislamoğlu, Ömer Yıldız, Halil Fırat Baytekin, Mithat Ekşi, Hakan Polat, Alper Bitkin, Ali İhsan Taşçı

“…According to the multivariate analysis, only tumor size and Gleason Score (GS) were independent predictors regarding the ability of mpMRI to detect tumor foci within the prostate (p<0.0001). …”
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The molecular prognostic scoring system for normal karyotype myelodysplastic syndromes by Wei Wang, Yudi Zhang, Wenli Yang, Xiaozhen Liu, Lingxu Jiang, Wei Lang, Yingwan Luo, Xinping Zhou, Lu Wang, Li Ye, Ying Xu, Liya Ma, Hongyan Tong

“…The IWG-PM cohort (n = 691) was used as an external independent validation set to evaluate the generalizability of the model. …”
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Negative perceptions toward older adults and life satisfaction among community-dwelling older citizens in Japan [version 2; peer review: 1 approved, 2 approved with reservations] by Yuho Shimizu, Hiroyuki Suzuki, Tomoki Furuya, Ai Iizuka, Keigo Hinakura, Tomoya Takahashi, Yan Li, Daichi Yamashiro, Yoshifumi Takahashi, Daisuke Cho, Susumu Ogawa, Kenichiro Sato

“…Instead of multilevel models, a multiple regression model with life satisfaction as the dependent variable and negative perceptions of older adults and demographics as the independent variables yielded the best fit. Results indicated that participants with more negative perceptions of older adults reported lower life satisfaction (β = -.16, 95% CI = [-.28, -.04], p = .008), supporting our hypothesis. …”
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DETERMINE THE POLICY TARGET TO INCREASE INSTITUTIONAL DELIVERY AMONG INDONESIAN FEMALE WORKERS by Isyatun Mardhiyah Syahri, Agung Dwi Laksono, Maya Fitria, Nikmatur Rohmah, Dina Bisara Lolong, Abdulah Saleh Alruwaili

“…In addition to institutional delivery as the dependent variable, we examined eight independent variables: residence, age, education, marital status, wealth, insurance, antenatal care (ANC), and parity. …”
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Racial disparities in acute care utilization among individuals with myasthenia gravis by Cynthia Qi, Pushpa Narayanaswami, Ashley E. L. Anderson, Deborah Gelinas, Yuebing Li, Jeffrey T. Guptill, Dakshinamoorthy Amirthaganesan, Charlotte Ward, Rupesh Panchal, Amit Goyal, Glenn Phillips

“…This study aimed to investigate the independent association between race/ethnicity and acute care utilization during the 2 years post-diagnosis among patients with MG.MethodsA retrospective cohort study was conducted among adults (≥18 years) with newly diagnosed MG in the United States using Optum’s de-identified Market Clarity Data from January 1, 2010, to December 31, 2019. …”
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