Evaluation of Clinical Variables Associated with Increased Carotid Intima-Media Thickness in Middle-Aged Hypertensive Women by Michelle Trindade, Renata Brum Martucci, Adriana K. Burlá, Wille Oigman, Mario Fritsch Neves, Denizar Vianna Araújo

“…In logistic regression, only HDL-cholesterol, CRP, and pulse pressure were shown to be independent variables associated to increased cIMT. …”
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Correlation between Obesity and Left Atrial Enlargement in Patients Using Cardiac Magnetic Resonance by Solos Jaturapisanukul, Yodying Kaolawanich, Methat Meechuen, Thananya Boonyasirinant

“…Other independent factors correlated with LA volume included the LV mass index and male sex. …”
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The importance of genotyping within the climate-smart plant breeding value chain – integrative tools for genetic enhancement programs by Ana Luísa Garcia-Oliveira, Rodomiro Ortiz, Fatma Sarsu, Søren K. Rasmussen, Paterne Agre, Asrat Asfaw, Moctar Kante, Subhash Chander

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A descriptive study of blood pressure in people with self-reported substance use seeking health care in region F, Johannesburg, South Africa by K.E. Oladimeji, S. Gumede, A. Nyatela, S. Nonyukela, R. Mohale, S.T. Lalla-Edward, D. Dwarka

“…The participants' median age was 41 years, and 35.9 % (772/2148) had elevated blood pressure, however only 16,9 % of the participants were receiving anti-hypertensive treatment. Independent factors associated with elevated blood pressure were increasing age - 30-39 years old (adjusted odds ratio (aOR) 2.78 [95 %CI 1.42–5.41], 40–49 years old (aOR 3.81 [95 %CI 1.95–7.46]), 50+ years (aOR 5.00 [95 %CI 2.45–10.20] and having comorbidities (aOR 2.35 [95 %CI 1.31–4.22]). …”
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The impact of exercise intensity and duration for swim training‐induced adaptations in cardiac structure and function in women with mild hypertension by Tórur Sjúrðarson, Nikolai B. Nordsborg, Jacobina Kristiansen, Lars Juel Andersen, Peter Krustrup, Kasper Kyhl, Magni Mohr

“…In conclusion, swim training for 15 weeks increased left ventricular mass and improved markers of diastolic function in mildly hypertensive women. These independent of exercise intensity and duration in mildly hypertensive women.…”
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Involvement of the TGF-β pathway in epithelialmesenchymal transition promoted by the pulmonary microenvironment in Mycoplasma pneumoniae pneumonia by Fan Lu, Wang Huixia, Xu Nuo, Guo Yun, Li Ling

“…Mycoplasma pneumoniae (MP), one of the smallest prokaryotic microorganisms capable of independent survival, causes respiratory tract infections and various extrapulmonary diseases. …”
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Access to HIV testing and factors associated among sexual minority women in a metropolitan region of the Brazilian Amazon by Janaína de Freitas Vale, Wanderson Santiago de Azevedo Júnior, Paula Regina Barbosa de Almeida, Adinaldo Moreira Martins, Flavine Evangelista Gonçalves, Eliã Pinheiro Botelho, Fabianne de Jesus Dias de Sousa, Cintia Yolette Urbano Pauxis Aben-Athar, Luiz Fernando Almeida Machado, Glenda Roberta Oliveira Naiff Ferreira

“…The dependent variable: participants were asked if they had ever been tested for HIV in their lifetime. The independent variables were the access components: predisposing, facilitating and necessary. 301 women from sexual minorities participated in the study, 42.2% of whom had never tested for HIV. …”
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Optimal exercise dose on Body Mass Index (BMI) in children and adolescents with overweight and obesity: a systematic review and bayesian model-based network meta-analysis by Zan Huang, Gang Sun, Jiayu Li, Bin Zhang, Guangping Lai, Hongwei Jing, Yulan Zhou

“…Methods A systematic search was conducted in Web of Science (Core Collection), PubMed/MEDLINE, Embase, Scopus, and the Cochrane Library for randomized controlled trials on relevant studies, covering literature up to July 2024. Three independent reviewers assessed bias via the Cochrane risk of bias tool. …”
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Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma by Zeynep Kacar, Eric Slud, Doron Levy, Julián Candia, Anuradha Budhu, Marshonna Forgues, Xiaolin Wu, Arati Raziuddin, Bao Tran, Jyoti Shetty, Yotsawat Pomyen, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Benjarath Pupacdi, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Chirayu Auewarakul, Suleeporn Sangrajrang, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin Wei Wang

“…Here we develop a strategy to determine the tumor clonality of three independent HCC cohorts of 524 patients with diverse etiologies and race/ethnicity by utilizing somatic mutations in cancer driver genes. …”
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Exploring Acute Kidney Injury Incidence in Hip Periprosthetic Joint Infection Treatment With Combined Intravenous and Intra-articular Antibiotic Infusion by Wenbo Mu, MD, PhD, Boyong Xu, MD, Fei Wang, MD, Wentao Guo, MD, PhD, Xiaogang Zhang, MD, Li Cao, MD

“…Diabetes and low baseline serum creatinine levels were identified as independent risk factors for AKI, with odds ratios of 9.69 and 1.09, respectively. …”
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Unlocking the link: predicting cardiovascular disease risk with a focus on airflow obstruction using machine learning by Xiyu Cao, Jianli Ma, Xiaoyi He, Yufei Liu, Yang Yang, Yaqi Wang, Chuantao Zhang

“…However, current CVD risk models inadequately consider AO as an independent risk factor. Therefore, developing an accurate risk prediction model can help identify and intervene early. …”
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Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis by Annie Elong Ngono, Maud Lepetit, Markus Reindl, Alexandra Garcia, Flora Guillot, Athénaïs Genty, Mélanie Chesneau, Marion Salou, Laure Michel, Fabienne Lefrere, Kathrin Schanda, Berthe-Marie Imbert-Marcille, Nicolas Degauque, Arnaud Nicot, Sophie Brouard, David-Axel Laplaud, Jean-Paul Soulillou

“…The striking alteration in MOG-specific B cells, independent of anti-MOG antibody titers, challenges our view on the role of MOG-specific B cells in MS.…”
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EZH2 inhibition induces pyroptosis via RHA-mediated S100A9 overexpression in myelodysplastic syndromes by Qi Zhang, Yingwan Luo, Li Ye, Yuxia Wang, Lu Wang, Wenli Yang, Wei Lang, Shuanghong Zhu, Lingxu Jiang, Weimei Jin, Chen Mei, Xinping Zhou, Yanling Ren, Liya Ma, Gaixiang Xu, Bowatte Gedara Lakmal Vimukthi Bandara Bowattage, Hongyan Tong, Jie Sun

“…Enhancer of zeste homolog 2 (EZH2) is an important regulator in gene expression through methyltransferase-dependent or methyltransferase-independent mechanisms. Herein, we found EZH2 inhibition led to MDS cell pyroptosis through RNA Helicase A (RHA) down-regulation induced overexpression of S100A9, a key regulator of inflammasome activation and pyroptosis. …”
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The effects of psychosocial and economic factors on the quality of life of patients with end-stage renal disease and their caregivers in Klang Valley, Malaysia: protocol for a mixe... by Norhayati Ibrahim, Sin Yee Chu, Ching Sin Siau, Noh Amit, Rozmi Ismail, Abdul Halim Abdul Gafor

“…Descriptive statistics, independent sample t-tests and multiple regression analysis will be used for analyses in phase I, and thematic analysis will be used in phase II.Ethics and dissemination Approval for the study has been obtained from the National Medical Research and Ethics Committee (MREC) (NMRR-21-1012-59714) and the Research Ethics Committee of Hospital Canselor Tuanku Muhriz UKM (UKM PPI/111/8/JEP-2021–078) and University of Malaya Medical Centre (MREC ID NO: 2 02 178–10346). …”
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Associations between inflammation and striatal dopamine D2-receptor availability in aging by Vanessa Crine, Goran Papenberg, Jarkko Johansson, Carl-Johan Boraxbekk, Anders Wåhlin, Ulman Lindenberger, Martin Lövdén, Katrine Riklund, Lars Bäckman, Lars Nyberg, Nina Karalija

“…No significant association was found between DNA methylation scores and white-matter lesions, but higher scores as well as higher lesion burden were independently associated with reduced striatal DRD2 availability in men. …”
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Retrospective Analyses of Potential Risk Factors for Posterior Capsule Opacification after Cataract Surgery by Shuang Wu, Nianting Tong, Lin Pan, Xiaohui Jiang, Yanan Li, MeiLing Guo, Hehuan Li

“…Multivariable data analyses using logistic regression analyses of the variables showed that age at the time of surgery <60 years, diabetes, lens nucleus hardness of III–V, extracapsular cataract extraction (ECCE), postvitrectomy, and hydrophilic IOLs were significant independent risk factors associated with PCO. Conclusions. …”
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Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint by Yan Wang, Xiaoye Jin, Rui Qiu, Bo Ma, Sheng Zhang, Xuyang Song, Jinxi He

“…The model was trained and validated using the Genomics of Drug Sensitivity in Cancer (GDSC) database, followed by independent validation with the Cancer Cell Line Encyclopedia (CCLE) dataset. …”
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Swiss chiropractic practice-based research network and musculoskeletal pain cohort pilot study: protocol of a nationwide resource to advance musculoskeletal health services researc... by Milo A Puhan, Viktor von Wyl, Alice Kongsted, Cesar A Hincapié, Léonie Hofstetter, Rahim Lalji

“…Surveys will be provided to patients prior to their initial consultation in clinics, 1 hour after initial consultation, and at 2, 6 and 12 weeks after initial consultation.Ethics and dissemination Ethics approval has been obtained from the independent research ethics committee of Canton Zurich (BASEC-Nr: 2021-01479). …”
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The effects of artificial sweeteners on body weight, body fat, and energy intake: A meta-analysis of meta-analyses by Fatemeh Hamedi-Kalajahi, Sanaz Asemani, Kousalya Prabahar, Neda Jourabchi-Ghadim, Alireza Ostadrahimi

“…Subgroup analyses were carried out based on various independent variables. The quality of the included meta-analyses was evaluated using the AMSTAR2 questionnaire. …”
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Balloon dilation for the treatment of male urethral strictures: a systematic review and meta-analysis by Tianyu Cai, Xiaoyu Li, Jian Lin, Chunru Xu, Xing Ji, Zhenpeng Zhu, Zhenke Guo

“…The aim of this study was to review and discuss the safety, efficacy and factors influencing the clinical application of balloon dilation for the treatment of male urethral strictures.Design Systematic review and meta-analysis.Data sources Embase, Medline, Web of Science, Cochrane Library and Scopus were searched for publications published before 17 July 2022.Study selection Two independent researchers screened and assessed the results, and all clinical studies on balloon dilation for the treatment of urethral strictures in men were included.Data extraction and synthesis The success rate, rate of adverse events, International Prostate Symptom Scores, maximum uroflow (Qmax) and postvoid residual urine volume were the main outcomes. …”
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