Development and validation of a nomogram to predict recurrence in epithelial ovarian cancer using complete blood count and lipid profiles by Xi Tang, Jingke He, Qin Huang, Yi Chen, Ke Chen, Jing Liu, Yingyu Tian, Hui Wang

“…Grade, International Federation of Gynecology and Obstetrics (FIGO) stage, platelet-to-lymphocyte ratio, red blood cell distribution width-coefficient of variation, triglycerides, and human epididymal protein 4 were identified as independent prognostic factors. The novel nomogram displayed a good predictive performance, with a concordance index (C-index) of 0.787 in the training group and 0.807 in the validation group. …”
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Testing General Relativity Using Large-scale Structure Photometric Redshift Surveys and the Cosmic Microwave Background Lensing Effect by Shang Li, Jun-Qing Xia

“…In this formulation, we reconstruct the growth rate of structure, fσ _8 ( z ), using the artificial neural network method, while simultaneously utilizing model-independent constraints on the parameter bσ _8 ( z ), directly obtained from the DES collaboration. …”
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Polydatin-Induced Shift of Redox Balance and Its Anti-Cancer Impact on Human Osteosarcoma Cells by Alessio Cimmino, Magda Gioia, Maria Elisabetta Clementi, Isabella Faraoni, Stefano Marini, Chiara Ciaccio

“…Interestingly, PD’s ability to hinder cell adhesion and migration appears independent of its pro-oxidant effect. Analysis of the oxidative stress regulators SIRT1 and Nrf2 at the gene and protein levels using real-time PCR and Western blot indicates an early oxidative response to PD treatment. …”
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Readiness for self-directed learning among undergraduate medical students in Khyber Pakhtunkhwa during COVID-19, Pakistan by Ejaz Hassan Khan, Ahsan Sethi, Syed Muhammad Junaid, Tania Khattak, Malghalara Khattak

“…Differences in SDL mean scores of student groups were analyzed through independent sample t-test for groups having two categories (e.g. gender, medical college setting etc.). …”
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The impact of death and caring for the dying and their families on surgeons - an AI assisted systematic scoping review by Jun Rong Tan, Yun Ting Ong, Victoria Jia En Fam, Annushkha Sinnathamby, Nila Ravindran, Yaoyi Ng, Lalit Kumar Radha Krishna

“…The findings of these assistive processes were compared with the independent thematic and content analysis carried out by the two research teams. …”
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Depressive and Anxiety Disorders in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations by Ru Bai, Shuang Liu, Yueyin Zhao, Yuqi Cheng, Shu Li, Aiyun Lai, Zhongqi Xie, Xinyu Xu, Zhaoping Lu, Jian Xu

“…HAMA and HAMD scores were in strong positive correlation and they were independent risk factors of each other. We concluded that the high prevalence of depression and anxiety and the association between depression and SLE disease activity might reveal the covert damage of central nervous system in SLE. …”
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Targeting EGFR-binding protein SLC7A11 enhancing antitumor immunity of T cells via inducing MHC-I antigen presentation in nasopharyngeal carcinoma by Haihua Wang, Songqing Fan, Yuting Zhan, Yue Xu, Yao Du, Jiadi Luo, Hongjing Zang, Shuping Peng, Weiyuan Wang

“…We discovered that EGFR, operating in a kinase-independent manner, played a role in stabilizing the expression of SLC7A11, which subsequently inhibited MHC-I antigen presentation. …”
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The Ratio of CD226 and TIGIT Expression in Tfh and PD-1+ICOS+Tfh Cells Are Potential Biomarkers for Chronic Antibody-Mediated Rejection in Kidney Transplantation by Ji-wen Fan, Yu Fan, Zheng-li Wan, Lin Yan, Ya-mei Li, Yang-juan Bai, Lan-lan Wang, Jie Chen, Yi Li

“…Using the logistic regression model, we concluded that the estimated glomerular filtration rate (eGFR), absolute number of PD-1+ICOS+Tfh cells, and ratio of CD226+Tfh cells to TIGIT+Tfh cells were independent risk factors for CAMR. The combination of eGFR, PD-1+ICOS+Tfh cells, and the ratio of CD226+Tfh cells to TIGIT+Tfh cells showed better diagnostic efficacy for CAMR than each single parameter. …”
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Individual differences in training time in the rat gambling task are unrelated to subsequent decision-making strategies by Frida A. Lindberg, Christakis Kagios, Christakis Kagios, Nikita Tjernström, Erika Roman, Erika Roman

“…Finally, learning time was independent of underlying behavioral profiles.DiscussionIn conclusion, neither decision-making strategies in the rGT nor behavioral profiles were correlated or differed between animals with different learning speed. …”
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Comparative Bioremediation of Crude Oil-Amended Tropical Soil Microcosms by Natural Attenuation, Bioaugmentation, or Bioenrichment by Vanessa Marques Alvarez, Joana Montezano Marques, Elisa Korenblum, Lucy Seldin

“…Over time, we found the degradation rate of n-alkanes was higher than TPH in both soils, independent of the treatment used. In fact, our data show that the total bacterial community in the soils was mainly affected by the experimental period of time, while the type of bioremediation treatment used was the main factor influencing the actinomycetes populations in both soils. …”
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Development and validation of a prediction model for chronic post-surgical pain risk: a single-center prospective study of video-assisted thoracoscopic lung cancer surgery by Xiong-Fei Zhang, Chang-Guo Peng, Hua-Jing Guo, Zhi-Ming Zhang

“…The model was internally validated in the internal test cohort to evaluate its discrimination, calibration, and clinical utility. Results Independent risk factors for CPSP included female gender, severe acute pain post-surgery, lymph node dissection, and cold pain sensation, while paravertebral nerve block was identified as a protective factor. …”
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Derivation of Sa-MoDEI score from DEI. Tak for prognostication in Buerger's Disease - Preliminary data of a prospective observational cohort by Gregory Pathrose, Albert A Kota, Prabhu Premkumar, Prasanna Samuel, Shivraj Padiyar, Deepak Selvaraj, Prasanta Padhan, Debashish Danda

“…The optimal Sa-MoDEI score cut-off for the bad outcome was 8 which corresponded with Youden's Index. Independent factors associated with bad outcome on multivariate analysis were age of onset below 39 years (Hazard Ratio [HR] = 6.00, 95% confidence interval [CI] (1.35–26.67), P = 0.019) and Sa-MoDEI score above 8 (HR = 9.77, 95% CI (2.60–36.71), P = 0.001). …”
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Effects of prophylactic antibiotic administration and antibiotic timing on culture results and clinical outcomes of paediatric musculoskeletal infection: a protocol for a randomise... by Chao You, Yibiao Zhou, Zhiyong Liu, Chao Deng, Yongjie Xia, Dechao Wu, Liangfu Xie, Bing E, Jingming Han

“…Statistical comparisons between the different patient groups regarding the confounding and outcome variables will be conducted using independent t-tests, Mann-Whitney U tests, χ2 tests and Fisher’s exact tests as appropriate with the significance level set to 5% (p<0.05).Ethics and dissemination This study has received ethical approval. …”
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Reconstruction of Partial Glossectomy Defects in Patients with Squamous Cell Carcinoma of Oral Tongue: A Prospective Clinical Study on the Assessment and Comparison of Intraoperati... by Shubhanshi Kangloo, Nitin Bhola, Anchal Agarwal, Raj Kumar Chakraborty, Priyatam Mishra, Saurabh Pillai

“…Intraoperative and postoperative outcomes were evaluated, and statistical analysis was performed using independent sample t-test and Chi-square test where values less than P = 0.05 were found significant. …”
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Nonlinear association between proteinuria levels and the risk of cardiovascular disease events and all-cause mortality among chronic kidney disease patients by Haiying Song, Yuheng Liao, Haofei Hu, Qijun Wan

“…A higher UPCR (when UPCR < 3.93 g/gCr) was an independent predictor of the primary outcome. Importantly, our study predates SGLT2 inhibitor use, showcasing outcomes achievable without these medications. …”
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HbA1c-Based Score Model for Predicting Death Risk in Patients with Hepatocellular Carcinoma and Type 2 Diabetes Mellitus by Lingling He, Shuan Zhang, Xiaoli Liu, Yuyong Jiang, Xianbo Wang, Zhiyun Yang

“…Univariate and multivariate logistic regression analysis was performed to obtain the independent factors associated with death risk. A new score model was devised according to these factors. …”
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In Vitro Effect of Acidic Solutions and Sodium Fluoride on Surface Roughness of Two Types of CAD-CAM Dental Ceramics by Elham Farhadi, Hamid Kermanshah, Shiva Rafizadeh, Reza Saeedi, Ladan Ranjbar Omrani

“…Data were analyzed using one-way and two-way ANOVA, Tukey’s test, and independent t-test. Results. Significant changes were noted in Ra (P=0.002) and Rq (P<0.0001) in both types of ceramics. …”
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Expression and prognosis of cellular senescence genes in head and neck squamous cell carcinoma by Chen Feng, Lijuan Zhu, Wei Mao, Pin Dong, Xinwei Chen

“…Analyses included survival analysis, ROC curve analysis, risk curve analysis, independent prognostic analysis and model validation for clinical grouping. …”
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Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow by Bianca Leistner, Dominic Rauschning, Ralf Matthias Hagen, Franziska Srečec, Nico Tom Mutters, Ruth Weppler, Christina Mutschnik, Manuel Döhla

“…In Germany, the reporting of hospital antibiotics consumption to an independent institution is only voluntary. Although a high level of willingness to improve can be assumed in the case of participation, the median consumptions of reporting hospitals change only slightly. …”
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Mental health and psychosocial support strategies in highly contagious emerging disease outbreaks of substantial public concern: A systematic scoping review. by Angela M Kunzler, Jutta Stoffers-Winterling, Marlene Stoll, Alexander L Mancini, Sophie Lehmann, Manpreet Blessin, Donya Gilan, Isabella Helmreich, Frank Hufert, Klaus Lieb

“…<h4>Methods</h4>MEDLINE, Cochrane CENTRAL, Web of Science (January 2000 to May 7, 2020), and reference lists were systematically searched and screened by two independent reviewers. Quantitative and qualitative studies investigating the effects of psychological interventions before, during, and after outbreaks of highly contagious emerging infectious diseases, such as SARS, MERS, Ebola, or COVID-19 were included. …”
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