The evaluation of the predictors of left ventricular systolic function improvement in patients with severe aortic stenosis after aortic valve replacement by N.V. Ponych, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

“…Critical AS with reduced LVEF, including low-flow, low gradient AS should not be regarded as an independent restriction to AVR.…”
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DisCo P-ad: Distance-Correlation-Based <i><b>p</b></i>-Value Adjustment Enhances Multiple Testing Corrections for Metabolomics by Debmalya Nandy, Debashis Ghosh, Katerina Kechris

“…Methods: One such multiple testing correction strategy is to estimate the number of statistically independent tests, called the <i>effective number of tests</i>, based on the eigen-analysis of the correlation matrix between the features. …”
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Optimizing the NGS-based discrimination of multiple lung cancers from the perspective of evolution by Ziyang Wang, Xiaoqiu Yuan, Kunkun Sun, Fang Wu, Ke Liu, Yiruo Jin, Olga Chervova, Yuntao Nie, Airong Yang, Yichen Jin, Jing Li, Yun Li, Fan Yang, Jun Wang, Stephan Beck, David Carbone, Guanchao Jiang, Kezhong Chen

“…ROC analysis highlighted MoleB’s superior performance, especially with the NCCNplus panel (AUC = 0.950 ± 0.002) and pancancer MoleA (AUC = 0.792 ± 0.004). In two independent cohorts (WES cohort, N = 42 and non-WES cohort, N = 94), NGS-based methodologies effectively stratified disease-free survival, with NCCNplus MoleB further predicting prognosis. …”
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Serum Galectin-3 Predicts Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients by Jianlong Zhu, Dehui Guo, Liying Liu, Jing Zhong

“…Further multivariable analysis showed that APACHE II score, BNP-T72, and Gal-3-T72 were independent risk factors for death in VA-ECMO patients. …”
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Gender and melanoma subtype‐based prognostic implications of MUC16 and TTN co‐occurrent mutations in melanoma: A retrospective multi‐study analysis by Nilesh Kodali, Simona Alomary, Abhijit Bhattaru, Ahmed Eldaboush, Robert A. Schwartz, Shari R. Lipner

“…Methods The cBioPortal database was queried for melanoma studies and returned 16 independent studies. Data from 2447 melanoma patients were utilized including those with ALM, cutaneous melanoma (CM), and melanoma of unknown primary (MUP). …”
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Evidence from NHANES 2011–2014: a correlation between the weight-adjusted-waist index and cognitive abilities in the United States by Chan Zhao, Xintian Xu, Chunyan Hao

“…The weight-adjusted waist index (WWI) serves as a more precise indicator of visceral obesity that is independent of weight, in contrast to body mass index (BMI). …”
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Ecological and human health implications of mercury contamination in the coastal water by A. Mallongi, A.U. Rauf, R.D.P. Astuti, S. Palutturi, H. Ishak

“…The uncertainty and sensitivity tests for independent variables in human health risk were assessed by the Monte Carlo Simulation method. …”
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High-Capacity Real-Time Face Retrieval Recognition Algorithm Based on Task Scheduling Model for the Treatment Area of Hospital by Yi Zhou, Weili Xia

“…., the function can be represented by a finite nonperiodic part and an infinitely repeated periodic part, thus calculating the coherent qualifying function independent of the magnitude of the interval time. The algorithm for high-capacity real-time face retrieval and recognition in the treatment area of hospital based on the task scheduling model is further investigated, and a face database is established by using the PCA dimensionality reduction technique. …”
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Interaction between the Haptoglobin 2 Phenotype and Diabetes Mellitus on Systolic Pulmonary Arterial Pressure and Nitric Oxide Bioavailability in Hemodialysis Patients by Inbal Dahan, Evgeny Farber, Nadia Thauho, Nakhoul Nakhoul, Adi Francis, Mohamad Awawde, Andrew P. Levy, Daniel B. Kim-Shapiro, Swati Basu, Farid Nakhoul

“…Elevated systolic pulmonary artery pressure (s-PAP, ≥35 mmHg) serves as an independent predictor of mortality in hemodialysis (HD) and diabetic (DM) patients. …”
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No Correlation Exists between Disease Activity and the Expression of Killer-Cell Immunoglobulin-Like Receptors in Patients with Rheumatoid Arthritis by Toshiaki Kogure, Takeshi Tatsumi, Atsushi Niizawa, Hiroshi Fujinaga, Tomoyuki Ito, Yutaka Shimada, Katsutoshi Terasawa

“…Additionally, in the 5 patients whose expression of KIRs particularly changed, the time-related changes in the expression of KIRs were independent from those of inflammation parameters and IgM-RF. …”
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Assessing Microbial Diversity in Páramo Soils (Multistrategy Analysis): Effects of Potato Farming and Livestock Grazing in Nevados National Natural Park, Colombia by Lizeth Manuela Avellaneda-Torres, Tomás León Sicard, Edlin Guerra Castro, Esperanza Torres-Rojas

“…Changes associated with potato farming and livestock grazing on microorganisms of Páramo soil of the Nevados National Natural Park (Nevados NNP) were assessed by (1) determination of physical and chemical properties (physicochemical matrix) and enzymatic activities associated (enzymatic activity matrix) with different biogeochemical cycles (C, N, and P); (2) microbial community functional diversity via evaluation of functional groups associated with carbon, nitrogen, and phosphorus cycles using cultivation-dependent techniques (arable functional group matrix and most probable number matrix); and (3) microbial diversity using cultivation-independent techniques that employ the hypervariable V5–V6 region of the 16S rRNA gene and pyrosequencing (16S-454 genus matrix and 16S-454 OTU matrix). …”
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Predictive value of integrated pulmonary index for the outcome of ventilator withdrawal failure in elderly patients with hypoxic respiratory failure by Nan Wu, Jin Liu, Xianrong Feng

“…The results of multivariate logistic regression analysis showed that IPI score was one of the independent factors of ventilator weaning failure in elderly patients with hypoxemic respiratory failure (P<0.05). …”
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Biomarkers of residual risk and all-cause mortality after acute coronary syndrome. by Anna Toso, Mario Leoncini, Mauro Maioli, Simona Villani, Francesco Bellandi

“…Conclusions: In this population on high-intensity statin therapy only hsCRP and eGFR were independently associated with medium-term mortality. …”
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Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents by Sun-Young Kim, Minsun Kim, Youngman Oh, Dae-Yeol Lee

“…However, insulin-like growth factor binding protein (IGFBP) also plays an important role in glucose homeostasis, although the IGF-independent role of IGFBP-3 in the glucose intolerance state is poorly understood. …”
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Prediction Score for Cervical Spine Fracture in Patients with Traumatic Neck Injury by Natsinee Athinartrattanapong, Chaiyaporn Yuksen, Sittichok Leela-amornsin, Chetsadakon Jenpanitpong, Sirote Wongwaisayawan, Pittavat Leelapattana

“…Results. 375 patients met the criteria. 29 (7.73%) presented with cervical spine fracture on computed tomography scan and 346 did not. Five independent factors (i.e., high-risk mechanism of injury, paraparesis, paresthesia, limited range of motion of the neck, and associated chest or facial injury) were considered good predictors of C-spine fracture. …”
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Association Between Vaso-Occlusive Crises and Opioid Prescriptions Among Patients with Sickle Cell Disease: A Retrospective Claims-Based Study by Hyeun Ah Kang, Jamie C. Barner, Kristin M. Richards, Menaka Bhor, Jincy Paulose, Abdullah Kutlar

“…The primary outcome was number of opioid prescriptions, while the independent variable was number of VOC events. Covariates included age, gender, nonopioid medication use, nonstudy SCD-related medication (penicillin and folic acid) use, evidence of blood transfusions, number of SCD-related complications, number of SCD-related comorbid conditions, and Charlson Comorbidity Index score. …”
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Nuclear Factor-Kappa B Activity Regulates Brain Expression of P-Glycoprotein in the Kainic Acid-Induced Seizure Rats by Nian Yu, Qing Di, Hao Liu, Yong Hu, Ying Jiang, Yu-kui Yan, Yan-fang Zhang, Ying-dong Zhang

“…Additionally, DEX pre-treatment only decreased P-gp expression level without inhibition of NF-κB activation, suggesting NF-κB independent pathway may also participate in regulating seizure induced P-gp over-expression.…”
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Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma by Patrick Pearson, Kendra Smith, Nilita Sood, Elizabeth Chia, Alicia Follett, Michael B. Prystowsky, Simon Kirby, Thomas J. Belbin

“…Methods We examined prognostic significance of ZNF154 and ZNF132 expression and DNA methylation in independent patient cohort of about 500 head and neck cancer patients in the Cancer Genome Atlas (TCGA). …”
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Identification of Decision-Making Skills of the High School Students Participating in School Sports Activities by Ayla Karakullukçu, Mehmet Öçalan, Pelin Avcı

“…In this study, the effect of two or more independent variables on more than one dependent variable was determined by two-way MANOVA analysis. …”
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Study on forming process and microstructure of FeCrAl-ODS alloy by selective laser melting by Shenghua Zhang, Fudong Li, Yu Wang, Zhonghua Li, Senming Zhang, Yen-Ling Kuo, Peikang Bai, Bin Liu

“…A higher laser coupling efficiency and melt pool temperature led to a lower proportion of subgrains composed of low-angle grain boundaries in the FeCrAl-ODS alloy. Independent α′ phase (Cr-rich phase) and α′ phase attached to Y₂O₃ were observed in the SLM-formed FeCrAl-ODS alloy. …”
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