Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model by Juan Sebastian Yakisich, Neelam Azad, Rajkumar Venkatadri, Yogesh Kulkarni, Clayton Wright, Vivek Kaushik, Anand Krishnan V. Iyer

“…In addition, we report that the FDA-approved drug Digitoxin, at concentration close to its therapeutic level, decreased the viability of LTSs and downregulated Sox2 independent of the PI3K/AKT pathway. The potential use of LTSs generated without the addition of any external mitogenic stimulation to study the role of specific factor(s) associated with stemness properties is also discussed.…”
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Enhancing proteasome activity by NMDAR antagonists explains their therapeutic effect in neurodegenerative and mental diseases by Fikret Sahin, Aslihan Gunel, Buse Turegun Atasoy, Ulku Guler, Bekir Salih, Isinsu Kuzu, Mehmet Taspinar, Ozgur Cinar, Selda Kahveci

“…Furthermore, the altered proteins exhibited enrichment in terms related to plasticity and potentiation, including retrograde endocannabinoid signaling—a pivotal pathway in both short- and long-term plasticity that may elucidate the long-lasting effects of ketamine in major depression. Via the ubiquitin-independent 20S proteasome pathway (UIPS), these drugs maintain cellular protein homeostasis, which is crucial as proteasome activity declines with age, leading to protein aggregation and disease symptoms. …”
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Promoting cross-culture research on moral decision-making with standardized, culturally-equivalent dilemmas: The 4CONFiDe set by Cinzia Cecchetto, Raffaella Ida Rumiati, Valentina Parma

“…To assess the contribution of the four conceptual factors used by Christensen et al. to the levels of arousal, valence and familiarity experienced with each dilemma, an independent group of Italian native speakers (n = 112) completed the 4CONFiDe set (Study 2). …”
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Placenta Creta: A Spectrum of Lesions Associated with Shallow Placental Implantation by Jerzy Stanek

“…The frequencies of 25 independent clinical and 40 placental phenotypes were statistically compared between the groups using chi-square test or analysis of variance where appropriate. …”
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Efektivitas Kelincahan dan Kecepatan dengan Kemampuan Menggirng Pada Permaian Sepak Bola by Awang Roni Effendi, Muhammad Suhairi, Heri Rustanto, Suramli Suramli4

“…This research is multiple correlational with the independent variables in this study are agility (X1) and speed (X2) and the dependent variable is the ability to dribble (Y). …”
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A cycle-based model to predict no usable blastocyst formation following cycles of in vitro fertilization in patients with normal ovarian reserve by Xue Wang, Chen-yue Dong, Cui-lian Zhang, Shao-di Zhang

“…Results Multivariate analysis identified three independent predictors: the number of day 3 (D3) embryos, the number of high-quality D3 embryos, and the number of embryos used for blastocyst culture. …”
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Anatomical variations in Eurasian wolf (Canis lupus lupus) (Carnivora: Canidae) of the salivary glands: A histological and histochemical investigation. by Joanna Klećkowska-Nawrot, Karolina Goździewska-Harłajczuk, Krzysztof Stegmann, Arkadiusz Dziech, Dariusz Łupicki, Gabriela Jędrszczyk, Igor Jucenco, Karolina Barszcz

“…The polystomatic sublingual gland consisted of several independent packets (from 6-7 to 7-8) and was a complex branched tubuloalveolar gland with seromucous secretion. …”
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Rapid and Nondestructive Determination of Egg Freshness Category and Marked Date of Lay using Spectral Fingerprint by Thomas O. S. Akowuah, Ernest Teye, Julius Hagan, Kwasi Nyandey

“…For eggs stored in ambient storage, LDA had 95.54% identification rate at 5 principal components, while at cold storage LDA has 100% identification rate at 5 principal components for determining the marked date of lay, and partial least square regression (PLS-R) gave R = 0.87 and RMSEI = 2.57 for ambient storage and R = 0.88 and RMSEI = 2.66 for cold storage in independent set, respectively. The results show that handheld spectrometer and multivariate analysis could be used for rapid and nondestructive measurement of egg freshness. …”
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Testicular Cancer Risk Awareness in Young Male by María Fernanda Cueva Moncayo, Lexter Mihalache, Edwin Marcelo Miranda

“…Medical students demonstrated greater knowledge on the topic compared to other disciplines. 91 % of male students did not receive information about the risk and importance of testicular self-examination from their doctors. 72 % of students did not seek independent information about testicular cancer. Only 29 % of the students occasionally performed testicular self-examination. …”
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PaySwitch: Smart Contract-Based Payment Switch for Off-Chain Payment Channel Networks by Anan Jin, Yuhang Ye, Brian Lee, Xiang Li, Yuansong Qiao

“…PaySwitch is designed to enable any peer in the PaySwitch to dynamically reallocate the deposits in their payment channels while maintaining the independence of each other to ensure the trustworthiness of the channel. …”
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Ozone therapy and kinesiology effectiveness in the COVID-19 aftermath. Yaguaramas, 2022 by Maydelin Pérez Reina, Maria Caridad Pérez Reina, Jorge Enrique Rodríguez León, Elizabeth Núñez Pérez, Isidro Lamote Matos, Idalmis Valero Valero

“…The studied variables: sex, age, sequelae, health status and functional independence; these last two, before and after treatment<strong>.…”
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Individual-specific strategies inform category learning by Jared S. Collina, Gozde Erdil, Mingyi Xia, Christopher F. Angeloni, Katherine C. Wood, Janaki Sheth, Konrad P. Kording, Yale E. Cohen, Maria N. Geffen

“…Next, we asked how stimulus-independent, individual-specific strategies informed learning. …”
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Tracing fineware production in the Neo-Assyrian empire: Neutron activation analysis of common and Palace Ware in the upper Tigris River Valley, Turkey. by Britt E Hartenberger, James A Davenport, Timothy Matney

“…If it was manufactured locally, as has been shown at the urban center of Tell Sheikh Hamad, potters in the imperial peripheries may have produced fineware pottery independent of direct imperial control.…”
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Disentangling Sources of Multifractality in Time Series by Robert Kluszczyński, Stanisław Drożdż, Jarosław Kwapień, Tomasz Stanisz, Marcin Wątorek

“…Most often, they are treated as two independent components, while true multifractality cannot occur without temporal correlations. …”
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Hexavalent chromium removal in a tannery industry wastewater using rice husk silica by D. Sivakumar

“…Isotherm models result indicated that the equilibrium data fitted well with the Langmuir isotherm than Freundlich isotherm, because of higher correlation created between dependent and independent variables. Thus, the adsorption method using rice husk silica powder was used effectively for removing Cr(VI) in the tannery industrial wastewater, seems to be an economical and worthwhile alternative over other conventional methods, because of their abundant source, low price, multi-purposes and antimicrobial properties.…”
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Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population by Anna Machalińska, Aleksandra Zakrzewska, Krzysztof Safranow, Barbara Wiszniewska, Bogusław Machaliński

“…Multivariate logistic regression model including age and sex showed that there were three independent predictors of abnormal meiboscore: older age (OR = 1.03, 95% CI = 1.01–1.04 per year, p=0.006), postmenopausal hormone therapy (OR = 4.98, 95% CI = 1.52–16.30, p=0.007), and the use of antiallergy drugs (OR = 5.85, 95% CI = 2.18–15.72, p=0.0004). …”
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Presence of Serum Antinuclear Antibodies Does Not Impact Outcomes in HBV-Related Acute-on-Chronic Liver Failure by Lin Lin, Bin Lin, Qing Lan, Longgen Liu, Jianchun Lu, Xiujun Zhang, Shuqin Zheng, Yuan Xue

“…In addition, TBIL, INR, WBC, and PLT, but not ANA, resulted as independent risk factors associated with 90-day mortality. …”
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A Qualitative Study of Factors Perceived to Influence Physical Activity among Young Athletes after ACL Reconstruction by Christin Zwolski, Timothy Rethorn, Staci Thomas, Jacqueline Goodway, Mark Paterno, Catherine Quatman-Yates, Laura Schmitt

“…Iterative coding with two independent coders and a peer debriefing process were used to identify themes from the data…”
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Cracked components under anti-plane loading: recent outcomes and future developments by F. Berto

“…Calculation of the SED shows that the position of the maximum SED is independent of plate thickness. Both for thin plates and for thick ones the maximum SED is close to the lateral surface, where the maximum intensity of the coupled mode II takes place.…”
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The effect of climatic variables on vegetation indices (Case study: Orange orchards in Hassan Abad, Darab County by ALI hashemi, Hojjatollah Yazdanpanah, Mehdi Momeni

“…To determine the significance of each independent variable in predicting the dependent variables, the artificial neural network method was employed. …”
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