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39961
An exploratory study of INPP4B, a biomarker of gemcitabine chemoresistance in pancreatic cancer
Published 2024-12-01“…Additionally, we analyzed follow-up data from pancreatic cancer patients to assess the impact of relevant targets on patient prognosis. …”
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39962
Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment
Published 2025-01-01“…RNA-seq analysis after target silencing by small interfering RNA (siRNA) was performed, followed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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39963
Early bactericidal activity of sitafloxacin against pulmonary tuberculosis
Published 2025-01-01“…Sputum for quantitative culture was collected 2 days before the study of drug administration, followed by 16 hours of overnight sputum collected daily for 7 days of monotherapy. …”
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39964
Large errors in soil carbon measurements attributed to inconsistent sample processing
Published 2025-01-01“…A finer grind generally resulted in a lower coefficient of variance, where the finest grind to <span class="inline-formula"><</span> 125 <span class="inline-formula">µ</span>m had the lowest coefficient of variance, followed by the <span class="inline-formula"><</span> 250 <span class="inline-formula">µ</span>m grind and, lastly, the <span class="inline-formula"><</span> 2000 <span class="inline-formula">µ</span>m grind. …”
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39965
Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA19...
Published 2025-01-01“…We extracted radiomic features from the original lesion-enhanced CT images (including baseline and subsequent follow-up CT scans), radiomic features from baseline 18F-fluoro-2-deoxy-2-D-glucose (18F-FDG) PET, and patient-specific features related to abdominal and visceral fat. …”
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39966
Dry eye syndrome before corneal refractive surgery: the prevalence and pathogenesis-oriented therapy
Published 2023-03-01“…To relieve the sterile inflammatory response, the patients received a course of steroids as anti-inflammatory agents followed by cyclosporin A. An eye gel was recommended for the long-lasting overnight hydration of the corneal epithelium and its faster renewal. …”
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39967
Análisis de habilidades y percepciones sobre mHealth en el manejo de pacientes crónicos por profesionales de atención primaria
Published 2025-02-01“…It also emphasizes the potential of mHealth to improve patient self-management and enhance electronic documentation of patient follow-up. Addressing the digital divide is critical to ensuring equitable access to mHealth and thereby improving health care and outcomes.…”
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39968
Effect of Traditional Chinese Medicine nursing combined with continuous nebulization in nursing of elderly patients undergoing tracheostomy (中医护理联合持续雾化吸入在老年气管切开患者护理中的应用效果观察)...
Published 2023-07-01“…The incidence of high sputum viscosity, respiratory tract irritation symptoms, airway mucosal damage and sputum blockage were observed during follow-up. Results Shorter duration of lung infection and retention time of tracheotomy catheter were observed in the study group than those in the control group (P<0. 05). …”
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39969
Novel type 2 diabetes prediction score based on traditional risk factors and circulating metabolites: model derivation and validation in two large cohort studiesResearch in context
Published 2025-01-01“…Additionally, we included 4383 participants from the German ESTHER cohort (recruited between 1 July 2000 and 30 June 2002 for external validation). Participants were followed up for 10 years to assess the incidence of type 2 diabetes. …”
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39970
Pratiques de l’automédication à l’ère de la pandémie COVID-19 dans trois villes de l’Ouest algérien [Practices of self-medication in the COVID-19 pandemic era in three cities of We...
Published 2023-06-01“…Paracetamol (83.67%) was the most consumed, followed by azithromycin (36.73%), prednisolone (31.10%),amoxicillin_clavulanic acid (30.53%), zinc (27.38%), vitamin C (27.08 %), vitamin D(16.31%), magnesium(12.92%),and even hydroxychloroquine(25.56%). …”
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39971
Evaluation of Some Cumin Ecotypes Based on Selection Index of Ideal Genotype
Published 2024-11-01“…Mean comparisons showed that the Sirjan ecotype produced the maximum value of grain yield (642.3 kg/ha), followed by Kerman, Khatam, and Ardakan ecotypes (634, 614.2, and 594 kg/ha, respectively). …”
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39972
Association between major depressive disorder or depressive symptoms and the risk of vascular complications among patients with type 2 diabetes, and the mediating role of metabolic...
Published 2025-01-01“…During an average of 13 years of follow-up, 2927 (21.36%) ASCVD, 1070 (7.81%) HF, and 2579 (18.82%) microvascular complications occurred. …”
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39973
Global, regional, and national burdens of heart failure in adolescents and young adults aged 10–24 years from 1990 to 2021: an analysis of data from the Global Burden of Disease St...
Published 2025-01-01“…Among all causes of HF, cardiomyopathy and myocarditis accounted for the highest proportion (32.7%) of prevalence cases of HF in 2021, followed by congenital birth defects (27.3%), and rheumatic heart disease (23.8%). …”
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39974
Real-World Evidence of Clinical Outcomes of the Use of the Adalimumab Biosimilar SB5 in Rheumatic and Gastrointestinal Immune-Mediated Inflammatory Diseases: 12-Month Data from the...
Published 2024-10-01“…SNDS pairing provided information on 68 of the 132 patients (52%) who were lost to follow-up in the clinical database, of whom 57 (84%) were confirmed persistent at M12 and 11 (16%) non-persistent. …”
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39975
Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association
Published 2018-08-01“…Implementation of clinical guidelines can promote improvement of healthcare quality for GERD patients and prevent complications, in particular if terms of treatment will be observed, at active outpatient followup for certain groups of patients.…”
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39976
Impact of Ketogenic and Mediterranean Diets on Gut Microbiota Profile and Clinical Outcomes in Drug-Naïve Patients with Diabesity: A 12-Month Pilot Study
Published 2025-01-01“…From the fourth month until the end of the study both groups followed a similar MD. Previous published results showed that VLCKD had a more beneficial impact than MD on several variables for 3 months of NI. …”
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39977
Association of accelerated phenotypic aging, genetic risk, and lifestyle with progression of type 2 diabetes: a prospective study using multi-state model
Published 2025-02-01“…Results During a median follow-up of 13.7 years, 17,615 participants developed T2D, of whom, 4,524 subsequently developed complications, and 28,373 died. …”
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39978
Additive effect of brimonidine in maximum tolerated medical therapy for primary open-angle glaucoma
Published 2021-09-01“…In group 1, target IOP was achieved, and these patients were followed up. In group 2, target IOP was not achieved, and these patients underwent trabeculectomy. …”
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39979
Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects
Published 2025-02-01“…For the in vitro luminescent-based CYP3A4 inhibition assay, both porcine liver and intestinal microsomes were extracted from their respective tissues by homogenization, followed by high-speed centrifugation and standardization before use. …”
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39980
Transition from paediatric to adult neurological care: What do we know?
Published 2025-01-01“…No consensus was observed regarding the duration of the transition (P=.029) and how long simultaneous follow-up must last after the transfer (P=.09). Conclusions: Due to increased survival rates, there is a need to create transition programmes for paediatric patients with neurological diseases. …”
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