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39901
Estimation of mangrove carbon stocks using unmanned aerial vehicle over coastal vegetation
Published 2024-07-01“…Aerial imagery was processed using the normalized difference vegetation index, followed by a regression analysis between normalized difference vegetation index and carbon stock values to obtain a carbon stock estimation model.FINDINGS: The results of the analysis of red-green-blue aerial imagery from the multispectral unmanned aerial vehicle has provided valuable insights into the extent of mangrove vegetation cover in the Lantebung mangrove forest area, revealing it to be 14.18 hectares. …”
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39902
ABO-incompatible liver transplantation – exploring utilitarian solutions to restricted access and organ shortages: A single-centre experience from Johannesburg, South Africa
Published 2024-04-01“…This retrospective record review compared all adult and paediatric patients receiving ABO-compatible (ABOc) and ABO-incompatible (ABOi) liver transplants from January 2014 to December 2021 with a minimum one-year follow-up. Primary outcomes were recipient and graft survival and secondary outcomes included vascular, enteric and biliary complications, relook surgery, acute cellular rejection (ACR) and lenghth of hospital stay. …”
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39903
Immunogenicity and safety of a COVID-19 DNA vaccine in healthy adults and elderly: A randomized, observer-blind, placebo-controlled phase 2 trial
Published 2025-12-01“…Eligible participants from each age group were enrolled and randomly assigned in a 3:3:2 ratio to receive two doses of INO-4800 (1.0 mg or 2.0 mg) or placebo, followed by electroporation on day 0 and day 28. The primary immunogenicity endpoints focused on determining the geometric mean titers (GMTs) of spike-binding antibodies and live SARS-CoV-2 neutralizing antibody at day 30 after the second dose. …”
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39904
Fasting for male fertility—a mixed methods study
Published 2025-01-01“…This study aimed at investigating feasibility and effects of a Fasting Mimicking Diet (FMD) in the context of male subfertility.Materials and methodsIn this two-arm, randomized, controlled, exploratory mixed methods study men with impaired sperm quality were randomized into a fasting and a waiting-list control group. The fasting group followed an FMD (500 kcal/d for 5 days) thrice within 4 months, while the control group was instructed to maintain their lifestyle and diet. …”
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39905
Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals
Published 2025-01-01“…We used Cox proportional hazards models to evaluate the relationship between baseline quartiles of the TyG-BMI index and its variability with CVDs and their subtypes.ResultsAmong the 7,072 participants (mean age of 59.1 ± 9.3 years), 3330 (47%) were male. During an average follow-up of 7.1 years, 1,774 (25.1%) participants developed new-onset cardiovascular diseases. …”
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39906
Significant role of biomass burning in heavy haze formation in Nanjing, a megacity in China: molecular-level insights from intensive PM<sub>2.5</sub> sampling on winter hazy days
Published 2025-01-01“…Results show that organic matter was the predominant species, followed by nitrate (NO<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M5" display="inline" overflow="scroll" dspmath="mathml"><mrow><msubsup><mi/><mn mathvariant="normal">3</mn><mo>-</mo></msubsup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="9pt" height="16pt" class="svg-formula" dspmath="mathimg" md5hash="8c72af1edd6d67ed562efcaf5163d22b"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="acp-25-73-2025-ie00001.svg" width="9pt" height="16pt" src="acp-25-73-2025-ie00001.png"/></svg:svg></span></span>). …”
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39907
SARS-COV-2 re-infection and incidence of post-acute sequelae of COVID-19 (PASC) among essential workers in New York: a retrospective cohort studyResearch in context
Published 2025-02-01“…Data were collected through in-person questionnaires and surveys sent via text and email, internal medical records, follow-up calls, and external medical records. Participants who reported continuation or the development of new symptoms three months after the initial SARS-CoV-2 infection, with symptoms lasting for at least two months, were categorized as having PASC, while those without any COVID-19 or whose symptoms resolved were classified as non-PASC. …”
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39908
Incident Heart Failure in Atherosclerotic Renal Artery Stenosis: A Post Hoc Analysis of the CORAL Trial
Published 2025-02-01“…Results: This analysis included 808 participants enrolled in the CORAL trial without evidence of baseline HF. During a median follow-up of 4.8 years, 54 participants (6.7%) developed incident HF. …”
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39909
Anti-LAG-3 antibody LBL-007 plus anti-PD-1 antibody toripalimab in advanced nasopharyngeal carcinoma and other solid tumors: an open-label, multicenter, phase Ib/II trial
Published 2025-02-01“…Results Between November 30, 2021, and December 1, 2023, 80 patients were enrolled, including 30 (37.5%) with NPC and 50 (62.5%) with other tumors. Median follow-up was 26.0 months. In Phase Ib, LBL-007 was administered at 200 mg to four patients and 400 mg to six patients, with no dose-limiting toxicities observed. …”
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39910
Recommendations for the diagnosis and treatment of anti-neutrophil cytoplasmic autoantibody associated vasculitis
Published 2025-01-01“…In recent years, a better knowledge of B lymphocyte function and the role of complement inhibition has transformed the course of this disease while minimising treatment-related adverse effects.This multidisciplinary document of recommendations is based on the consensus of three scientific societies (Internal Medicine, Nephrology and Rheumatology) and on the best available evidence on diagnosis, treatment and follow-up of patients with ANCA-associated vasculitis, including some special situations. …”
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39911
The Importance of Dose Escalation in the Treatment of Pulmonary Arterial Hypertension with Treprostinil
Published 2025-01-01“…Classification of patients according to the tertiles of treprostinil dose achieved at 3 months after drug inclusion shows that after 12 months of follow-up, the median WHO FC in the highest dose group was lower than that in the intermediate dose group (WHO FC II vs. …”
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39912
An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape
Published 2025-01-01“…Primary docking was performed using ZDOCK (3.0.2) to generate the initial conformation of the antigen-antibody complex, followed by simulations of the complete conformations using Rosetta SnugDock software. …”
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39913
A comparative analysis of autograft choices of anterior cruciate ligament reconstruction and their effects on muscle strength and joint biomechanics
Published 2025-01-01“…Quadriceps and hamstring peak torque (QPT and HPT, respectively) as indicators of isokinetic muscle strength were assessed both postoperatively and follow-up after approximately six months (mean 6.29 ± 1.70 months)ResultsSignificant differences in QPT and HPT recovery between the healthy and injured legs were found in all graft groups (P < 0.001). …”
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39914
RETRACTED: Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study
Published 2023-05-01“…We explored the mechanism of action of asparagus in MM through network pharmacology and experimental verification.Methods: The active ingredients and corresponding targets of asparagus were acquired from the Traditional Chinese Medicine System Pharmacology database, followed by identification of MM-related target genes using GeneCards and Online Mendelian Inheritance in Man databases, which were matched with the potential targets of asparagus. …”
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39915
Overview: quasi-Lagrangian observations of Arctic air mass transformations – introduction and initial results of the HALO–(𝒜 𝒞)<sup>3</sup> aircraft campaign
Published 2024-08-01“…Two low-flying and one long-range, high-altitude research aircraft were flown in colocated formation whenever possible. To follow the air mass transformations, a quasi-Lagrangian flight strategy using trajectory calculations was realized, enabling us to sample the same moving-air parcels twice along their trajectories. …”
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39916
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti...
Published 2023-01-01“…Furthermore, RNA sequencing revealed nuclear factor-kB (NF-κB) pathway induction as a response to CI-994 treatment, followed by transglutaminase 2 (TGM2) expression, which enhanced inflammatory cytokine secretion. …”
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39917
Outcome and prognostic value of N‐terminal pro‐brain natriuretic peptide and high‐sensitivity C‐reactive protein in mildly dilated cardiomyopathy vs. dilated cardiomyopathy
Published 2022-06-01“…Of 282 patients who had follow‐up echocardiograms ≥ 6 months, 7 MDCM patients (11.1%) evolved to DCM and 70 DCM patients (32.0%) recovered to MDCM by the change of LVEDDi. …”
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39918
Micro-nano aerated subsurface drip irrigation and biochar promote photosynthesis, dry matter accumulation and yield of cucumbers in greenhouse
Published 2025-03-01“…Three levels concentrations of dissolved oxygen (DO) in MNBW: O1 (4–5 mg/L), O2 (9–10 mg/L), and O3 (14–15 mg/L), as well as three levels amount of biochar application (BA): B1 (20 t/hm2), B2 (40 t/hm2), and B3 (60 t/hm2), and one control group (CK, O: 4–5 mg/L, B: 0 t/hm2) were the subjects of this study, followed by a two-factor randomized block design. The study examined the aeration practices of the red soil (clay) and the responses of greenhouse-grown cucumbers to SDI over the first and second growing seasons. …”
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39919
Post-acute sequelae of hospitalised COVID-19 re-infection compared with hospitalised first-time infection: a population-based retrospective cohort study in Hong Kong
Published 2025-01-01“…Subgroup analyses were conducted by age (<65 and ≥65 years), sex, Charlson Comorbidity Index (0–4, ≥5), COVID-19 vaccination (0–1, 2+doses) and hospitalisation status of previous infection.Results 2244 patients with hospitalised COVID-19 re-infection and 58 894 patients with hospitalised first-time COVID-19 infection were included. After a median follow-up of 170 days, re-infection was associated with a significantly higher risk of post-acute all-cause mortality compared with first-time infection (adjusted HR (95% CI): 1.366 (1.166 to 1.600); incidence rate (95% CI): 7.3 (7.1 to 7.5) vs 4.6 (4.4 to 4.7) per 10 000 person-days), all-cause hospital readmission (1.297 (1.200 to 1.403); 50.5 (49.8 to 51.1) vs 28.1 (27.8 to 28.5)), and attendance to emergency departments (1.307 (1.199 to 1.425); 35.4 (34.8 to 35.9) vs 21.9 (21.6 to 22.2)). …”
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39920
Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigationResearch...
Published 2025-03-01“…During 100,619 person-years of follow-up, 2168 had any fracture, and 538 had a hip fracture. …”
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