Surgical repair of conjunctival defects: perspectives and limitations by M.B. Gushсhina, A.V. Tereshchenko, A.V. Gushchin, D.S. Afanasyeva

“…The mean age of participants was 36.86±19.46 years. Follow-up was 1.5 to 6.5 years. The patients were divided into two groups. …”
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Modification and analysis of context-specific genome-scale metabolic models: methane-utilizing microbial chassis as a case study by M. A. Kulyashov, R. Hamilton, Y. Afshin, S. K. Kolmykov, T. S. Sokolova, T. M. Khlebodarova, M. G. Kalyuzhnaya, I. R. Akberdin

“…The phenotype of the fdhAB mutant followed the model prediction. Furthermore, a more significant reduction of the biomass yield was observed during growth in La-supplemented media, confirming a higher flux through formate. …”
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Neurological manifestations associated with COVID-19 vaccine by R. Alonso Castillo, J.C. Martínez Castrillo

“…Most of the published cases occurred in temporal association with the Pfizer vaccine (BNT162b2), followed by the AstraZeneca vaccine (ChAdOX1-S). Conclusions: It is not possible to establish a causal relationship between these adverse events and COVID-19 vaccines with the currently existing data, nor to calculate the frequency of appearance of these disorders. …”
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Phenotypes of primary sclerosing cholangitis in children by M.B. Dyba, V.S. Berezenko

“…Retrospective and prospective analysis of the clinical course of primary sclerosing cholangitis in children and adolescents who were treated and followed at the Department of Pediatric Hepatology from 2016 to 2024 was conducted. …”
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Effects of Different Ratios of Mixed Silage of Licorice Stems and Leaves and Whole Corn on Fermentation Quality, Microbial Diversity, and Aerobic Stability by Qifeng Gao, Yuliang Sun, Limin Tang, Haonan Liu, Chenchen Yang, Yulan Ren, Fangpeng Liu, Chunying Jia, Houjun Yu, Tao Jiang

“…At the phylum level, the dominant bacterial phylum in each group was Firmicutes, followed by Proteobacteria, while the abundance of Bacteroidetes in the G5Y5 group was significantly higher than that in the other groups (<i>p</i> < 0.05). …”
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The measurement of microplastics in surface water and their impact on histopathological structures in wading birds of district Lahore by Shaza Mehboob, Khalid Mahmood Anjum, Hamda Azmat, Muhammad Imran

“…The frequency and prevalence percentages followed the order: 0.5 mm &gt; 0.5–1 mm &gt; 1–2 mm &gt; 2–3 mm &gt; 3–4 mm &gt; 4–5 mm &gt; 0 mm (0 mm as control).This investigation contributes to the growing documentation of MPs abundance in freshwater ecosystems and provides a baseline for future studies on MPs pollution in the Ravi River.…”
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Hospital and physician-based mental healthcare during 12 months of opioid agonist treatment for opioid use disorder: Exploring costs and factors associated with acute care. by Tea Rosic, Glenda Babe, Myanca Rodrigues, Brittany B Dennis, Richard Perez, Claire de Oliveira, Andrew Worster, Lehana Thabane, Zainab Samaan

“…<h4>Findings</h4>Altogether, 14.9% of individuals had mental health-related acute care ED visits or hospitalizations and 37.3% had outpatient mental health visits during the follow up period. For participants with at least one visit, we determined the mean number of ED visits (1.93, standard deviation [SD] = 2.15), hospitalizations (1.46, SD = 1.05), primary care visits (3.51, SD = 4.31), and psychiatry visits (4.04, SD = 4.73). …”
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A Comparative Study of the Reasons for the Persistence of Buddhism and the Decline of Zoroastrianism in Ancient China by Amin Yazdkhasti, Hamidreza Pashazanous

“…It seems that most of the followers of the Zoroastrian religion in China were non-Chinese. …”
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Cognitive function differs across healthy lifestyle behavior profiles: a 10-year population-based prospective cohort study by Huixiu Hu, Yajie Zhao, Di Guo, Ying Deng, Huanhuan Luo, Yuqing Hao, Chao Sun, Kang Yu

“…Results: During a 10-year follow-up period, 2017 (37.5%) out of 5381 participants developed cognitive impairment. …”
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Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome by Nadja Scherbakov, Marvin Szklarski, Jelka Hartwig, Franziska Sotzny, Sebastian Lorenz, Antje Meyer, Patricia Grabowski, Wolfram Doehner, Carmen Scheibenbogen

“…Nine of these patients with elevated antibodies against β2‐adrenergic receptor underwent immunoadsorption, and endothelial function was measured at baseline and 3, 6, and 12 months follow‐up. ED was defined by reactive hyperaemia index ≤1.81. …”
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Assessment of hemodynamic disturbances and impaired ventricular filling in asymptomatic fontan patients: A 4D flow CMR study by Li-Wei Hu, Xiaodan Zhao, Shuang Leng, RongZhen Ouyang, Qian Wang, Ai-Min Sun, Yi-Man Liu, Wei Dong, Liang Zhong, Yu-Min Zhong

“…Consequently, long-term follow-up of individuals who have undergone the asymptomatic Fontan procedure is essential. …”
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Evaluating small coronary stents with dual-source photon-counting computed tomography: effect of different scan modes on image quality and performance in a phantom by Thomas Stein, Constantin von zur Muhlen, Niklas Verloh, Till Schürmann, Tobias Krauss, Martin Soschynski, Dirk Westermann, Jana Taron, Elif Can, Christopher L. Schlett, Fabian Bamberg, Christopher Schuppert, Muhammad Taha Hagar

“…Among all CT acquisition modes, the highest image quality was obtained for the UHR mode [median score: 4 (interquartile range (IQR): 3.67–4.00)] (P = 0.0015, with 37.5% rated as “excellent”), followed by the sequential mode [median score: 3.5 (IQR: 2.84–4.00)], P = 0.0326 and the spiral mode [median score: 3.0 (IQR: 2.53–3.47), P > 0.05]. …”
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A novel ddPCR™ assay for eDNA detection and quantification of Greater Amberjack Seriola dumerilli and three congeners in US waters: challenges and application to fisheries independ... by P. Joana Dias, Ryan Lehman, Bryan L. Huerta-Beltrán, Ana Wheeler, Crystal L. Hightower, Jessica Heise, Theodore Switzer, Clint Rhode, J. Marcus Drymon, Lynne Stokes, Mark A. Albins, Sean Powers, Nicole Phillips

“…To achieve this, investment into follow-up studies with increased sample sizes and spatial and temporal replication would be necessary to allow for year-to-year comparisons and validate the robustness of the correlation observed.…”
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Combining Charlson comorbidity and VACS indices improves prognostic accuracy for all-cause mortality for patients with and without HIV in the Veterans Health Administration by Kathleen A. McGinnis, Amy C. Justice, Amy C. Justice, Vincent C. Marconi, Vincent C. Marconi, Maria C. Rodriguez-Barradas, Maria C. Rodriguez-Barradas, Ronald G. Hauser, Ronald G. Hauser, Krisann K. Oursler, Krisann K. Oursler, Sheldon T. Brown, Kendall J. Bryant, Janet P. Tate, Janet P. Tate, for the Veterans Aging Cohort Study

“…Baseline predictors included age, and components of CCI and VACS Index (excluding CD4 count and HIV RNA). Patients were followed until December 31, 2021. We used Cox models to develop the VACS-CCI score and estimated mortality using a parametric (gamma) survival model. …”
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Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors by Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio, Julien Taieb, David Tougeron, Margherita Ambrosini, Michael J Overman, Alice Boilève, Lisa Salvatore, Rosine Guimbaud, Priya Jayachandran, Frank A Sinicrope, Thibault Mazard, Javier Ros, Vincenzo Nasca, Simon Pernot, Emily Alouani, Marie Decraecker, Emilie Hafliger, Pauline Parent

“…Median duration of treatment was ~7 months in the ETD and ~24 months in the LTD group. After a median follow-up of 44 months (IQR: 30–67), similar PFS (HR: 0.92, 95% CI: 0.60 to 1.40, p=0.69) and OS (HR: 1.15, 95% CI: 0.66 to 1.99, p=0.62) from the start of ICIs were observed in ETD and LTD patients. …”
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Steady-state mixing state of black carbon aerosols from a particle-resolved model by Z. Zhang, Z. Zhang, J. Wang, J. Wang, J. Wang, J. Wang, N. Riemer, C. Liu, C. Liu, Y. Jin, Y. Jin, Z. Tian, Z. Tian, J. Cai, J. Cai, Y. Cheng, Y. Cheng, G. Chen, G. Chen, B. Wang, B. Wang, S. Wang, A. Ding, A. Ding

“…The distribution of CT follows an exponential linear distribution and can be characterized by a single slope parameter <span class="inline-formula"><i>k</i></span>. …”
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Recomendaciones para el diagnóstico y tratamiento de las vasculitis asociadas a anticuerpos anticitoplasma de neutrófilo by Enrique Morales, Iñigo Rúa-Figueroa, José Luis Callejas Rubio, Ana Ávila Bernabéu, Ricardo Blanco Alonso, Maria C. Cid Xutgla, Gema Fernández Juárez, Natalia Mena-Vázquez, Juan José Ríos Blanco, Joaquín Manrique Escola, F. Javier Narváez García, Bernardo Sopeña, Luis F. Quintana Porras, Susana Romero-Yuste, Roser Solans Laqué

“…In recent years, a better knowledge of B lymphocyte function and the role of complement inhibition has transformed the course of this disease while minimising treatment-related adverse effects.This multidisciplinary document of recommendations is based on the consensus of three scientific societies (Internal Medicine, Nephrology and Rheumatology) and on the best available evidence on diagnosis, treatment and follow-up of patients with ANCA-associated vasculitis, including some special situations. …”
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Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated colorectal cancer—results from the FIRE‐4.5 study by Susanne Klein‐Scory, Alexander Baraniskin, Wolff Schmiegel, Thomas Mika, Roland Schroers, Swantje Held, Kathrin Heinrich, David Tougeron, Dominik P. Modest, Ingo Schwaner, Jan Eucker, Rudolf Pihusch, Martina Stauch, Florian Kaiser, Christoph Kahl, Meinolf Karthaus, Christian Müller, Christof Burkart, Sebastian Stintzing, Volker Heinemann

“…Patients with detectable BRAF mutations showed a clear superiority of FOLFOXIRI plus bevacizumab with regard to PFS (10.4 vs 5.7 months; HR 0.4; P = 0.009) and OS (16.6 vs 11.6 months; HR 0.5; P = 0.15), while this was not the case for BRAF wild‐type patients. Follow‐up LBs were obtained from 51 patients. Patients converting from BRAF V600E mutant to a BRAF V600 wild‐type status (36%, N = 18) had a superior PFS (8.6 vs 2.3 months; P = 0.0002) and OS (17.4 vs 5.1 months; P < 0.0001) compared to patients with stable or increased mutational allele frequency (12%, N = 6). …”
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Spatiotemporal analysis of Plasmodium falciparum erythrocyte binding antigen-175 gene dimorphism in Ghana by Abraham Y. Kpirikai, Belinda A. Ofosu, Josie N. A. Okai, Victor Kornu, Abdul Rashid Kassim, Esther Donkor, Frederica Malm, Osumanu Ahmed, Mona-Liza E. Sakyi, Samirah Saiid, Albert Yao Kudakpo, Charles Mensah, Francis Dzabeng, Collins Morang’a, Gordon A. Awandare, Yaw Aniweh, Lucas N. Amenga-Etego

“…Conclusion The F-allele was the most prevalent form across all age groups, followed by the C allele and mixed F/C alleles. No significant difference in allele prevalence was observed between the high malaria season (wet) and low malaria season (dry). …”
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Sustainability index analysis for environmentally low-input integrated farming by E. Widjaja, B.N. Utomo, A.D. Santoso, Y.P. Erlambang, . Surono, M.A. Firmansyah, S. Handoko, E. Erythrina, M.N. Rofiq, D. Iskandar, N.A. Sasongko, T. Rochmadi, N. Abbas, M. Hanif, Y.S. Garno, F.D. Arianti, N.D. Suretno, M. Askinatin, C.O.I. Hastuti, F. Fahrodji

“…Based on the analysis results, the social dimension had a sustainable index score of 93.79 percent, followed by economic (90.57 percent), institutional (88.39 percent), environmental (83.45 percent), and technology (74.29 percent). …”
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