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39441
Study of absorbable dural sealant to improve complications after craniocerebral surgery and its application strategy and standardized operation procedure
Published 2025-02-01“…We divided the included patients into 3 groups. Normalized group follows the ADS standard use process proposed by us, while Empirical group does not meet or only partially meets the ADS standard use process, or uses ADS based on its own experience, and Non-sealant group were patients who did not use ADS. …”
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39442
Balancing environmental impact: A sustainability index analysis of sorghum production for food and feed
Published 2024-01-01“…Analysis across four dimensions showed that the social dimension had the highest (83.80) sustainability index, followed by the technological (82.28), economical (77.46), and environmental (75.15) dimensions. …”
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39443
Prominent efficacy and good safety of sequential CD19 and CD22 CAR-T therapy in relapsed/refractory adult B-cell acute lymphoblastic leukemia
Published 2025-01-01“…The median OS was not reached with a median follow-up of 19.4 months (range 8.7–45.6), while the median LFS was 20.8 months. …”
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39444
Prevalence, Incidence and Predictors of Anal HPV Infection and HPV-Related Squamous Intraepithelial Lesions in a Cohort of People Living with HIV
Published 2025-01-01“…No patient developed SCC during follow-up. However, a high incidence of new cytological abnormalities and new HPV infections was observed. …”
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39445
An investigation and analysis of nursing undergraduates’ demands for clinical teaching (本科护理实习生临床教学需求调查分析)
Published 2023-03-01“…Results The most-demanded issue of clinical teaching was combination of theory and practice (95. 53%), followed by the clinical experience teaching (88. 27%). …”
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39446
Antitumor effect of a new human epidermal growth factor receptor inhibitor
Published 2024-09-01“…In both groups administration was carried out before natural death of animals according to the scheme: administration daily for 5 days, followed by 2 days of break. The dynamics of animal weight, dynamics of tumor node volume were evaluated, the tumor growth inhibition index (TGII) was calculated.Results. …”
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39447
Cohort profile: the BangladEsh Longitudinal Investigation of Emerging Vascular and nonvascular Events (BELIEVE) cohort study
Published 2025-01-01“…Regular longitudinal follow-up is ongoing for ascertainment and adjudication of a range of fatal and non-fatal health outcomes among participants. …”
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39448
The origin and transmission of HIV-1 CRF80_0107 among two major first-tier cities in China
Published 2025-01-01“…Methods With the partial pol region fragment of the HIV-1 CRF80_0107 subtype standard sequence as a reference, BLAST was used to search for highly similar sequences in the Los Alamos HIV Sequence Database, followed by preliminary subtype identification via COMET. …”
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39449
Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study
Published 2023-06-01“…The factors associated with complete response to tocilizumab at 6 months in multivariate analysis, only age <30 years (OR 2.85, 95% CI 1.14 to 7.12; p=0.027) and time between TAK diagnosis and tocilizumab initiation (OR 1.18, 95% CI 1.02 to 1.36; p=0.034). During the median follow-up of 30.1 months (0.4; 105.8) and 10.8 (0.1; 46.4) (p<0.0001) in patients who received tocilizumab in intravenous and SC forms, respectively, the risk of relapse was significantly higher in TAK patients on SC tocilizumab (HR=2.55, 95% CI 1.08 to 6.02; p=0.033). …”
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39450
Errors Associated With Medication Administration by a Nurse During Hospitalisation: A Prospective Observational Multicentric Study
Published 2025-01-01“…MAEs were collected when nurses administered medications to the adult inpatients during the morning, noon, and evening medication rounds at the internal, surgical, and follow‐up care departments in each hospital over three consecutive days. …”
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39451
Dupilumab in children with eosinophilic esophagitis: a retrospective multicenter study
Published 2025-02-01“…A longitudinal, large prospective study is necessary to guide the initiation of dupilumab treatment for childhood EoE, and long-term follow-up data on dupilumab are required. Clinical trial number Not applicable.…”
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39452
Titanium nanotubes modulate immunophenotyping and cytokine secretion of T cells via IL-17A: a bioinformatic analysis and experimental validation
Published 2025-01-01“…Notably, the NT40 group exhibited the lowest T-bet expression (P<0.05) along with the highest levels of Rorγt, Gata3, and Foxp3(P<0.05), followed by the NT15 group. Additionally, the NT40 group demonstrated reduced RANKL, TNF-α, and IL-6 (P<0.05) and increased OPG and IL-10 (P<0.05). …”
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39453
Effectiveness of the Chronic Care Model in Type 2 Diabetes Management in a Community Health Service Center in China: A Group Randomized Experimental Study
Published 2019-01-01“…A total of 258 patients (134 in intervention and 124 in control) who completed the baseline and follow-up evaluations and the entire intervention were included in the final analyses. …”
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39454
Metabolic profiling of Perilla leaves of different colors: insights into metabolite variation and bioactive compound distribution
Published 2025-01-01“…It was noteworthy that most of the differentially accumulated flavonoids showed a higher relative content in PF3, followed by PF2 and PF1. Glycosylated cyanidins and delphinidins were identified as the key compounds responsible for the purple coloration of leaves. …”
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39455
Several factors that predict the outcome of large B‐cell lymphoma patients who relapse/progress after chimeric antigen receptor (CAR) T‐cell therapy can be identified before cell a...
Published 2024-09-01“…Of these patients, 39 received radiotherapy or systemic therapy, with an ORR of 22% (CR 8%). The median follow‐up of surviving patients in whom treatment failed was 10.6 months. …”
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39456
Lipids as key biomarkers in unravelling the pathophysiology of obesity-related metabolic dysregulation
Published 2025-02-01“…Metabolites were identified using a molecular feature and chemical formula algorithm, followed by a differential analysis using MetaboAnalyst 5.0. …”
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39457
Construction of "One Syndrome and One Product" Traditional Chinese Medicine nursing service in the specialized spine department (脊柱专科“一证一品”中医特色护理服务品牌建设思路)...
Published 2021-07-01“…The nursing plan consisted of several important steps as follows: establishing standardized nurse etiquette and service behavior; creating the clinical ward with comfort and warm surroundings; carrying out preparation services for discharged patients; improving nursing service experience to satisfy patients; Strengthening basic nursing and creating a humanistic care service model for patients. …”
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39458
Comparison of Therapeutic Effects of Different Rehabilitation Methods on Patients Undergoing Total Knee Arthroplasty: A Network Meta‐Analysis of Randomized Controlled Trials
Published 2025-02-01“…Finally, 32 trials involving 2292 patients were included, the mean age of the enrolled patients was ~69.10 years, the sex ratio of males was (31.6%), and the longest follow‐up time was 2 years. And we have summarized nine rehabilitation intervention measures: conventional physical therapy (CPT), cryotherapy, thermal therapy (TT), acupuncture, hydrotherapy, neuromuscular training (NT), electrotherapy, continuous passive motion (CPM), continuous active motion (CAM). …”
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39459
Web-based mindfulness and skills-based distress reduction for patients with cancer: study protocol of the multicentre, randomised, controlled confirmatory intervention trial Reduct
Published 2022-06-01“…The proposed trial incorporates four distinct measurement time points: the baseline assessment before randomisation, a post-treatment assessment and 3 and 6 month follow-up assessments. We will include patients who have received a cancer diagnosis in the past 12 months, are in a curative treatment setting, are 18–65 years old, have given informed consent and experience high perceived psychological distress (Hospital Anxiety and Depression Scale ≥13) for at least 1 week. …”
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39460
Surgery for Patients With cT3/4N2M0, Stage IIIB NSCLC. Is It Time to Redefine Resectability?
Published 2025-01-01“…Introduction: Chemoradiation followed by durvalumab is considered a standard approach for patients with locally advanced NSCLC. …”
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