Synthesis, Characterization, and DNA-Binding Kinetics of New Pd(II) and Pt(II) Thiosemicarbazone Complexes: Spectral, Structural, and Anticancer Evaluation by Simon N. Mbugua, Lydia W. Njenga, Ruth A. Odhiambo, Shem O. Wandiga, Mervin Meyer, Nicole Sibuyi, Roger A. Lalancette, Martin O. Onani

“…In a bid to come up with potential anticancer agents, a class of thiosemicarbazone ligands bearing substituted thiophene were synthesized followed by complexation with various Pd(II) and Pt(II) metal precursors. …”
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Spatiotemporal variation in biomass abundance of different algal species in Lake Hulun using machine learning and Sentinel-3 images by Zhaojiang Yan, Chong Fang, Kaishan Song, Xiangyu Wang, Zhidan Wen, Yingxin Shang, Hui Tao, Yunfeng Lyu

“…Cyanophyta dominated the biomass abundance (44.62 ± 3.47%), followed by Bacillariophyta (36.35 ± 2.68%), and Chlorophyta had the lowest proportion (10.42 ± 1.08%). …”
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Causes and determinants of infant mortality using verbal autopsy and social autopsy methods in a rural population of Odisha: a community-based matched case-control study by Amit Kumar Satapathy, Arvind Kumar Singh, Priyamadhaba Behera, Debkumar Pal, Abhisek Mishra

“…We selected an equal number of alive infants matched with cases in a 1:1 ratio with regard to age, gender and residential address.Outcome measures We conducted the verbal autopsy using the Sample Registration System verbal autopsy tool, where the cause of death ascertainment was done by two independently trained physicians followed by adjudication by one senior trained physician in case of conflicts. …”
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Diagnostic and Predictive Values of Inflammatory Factors in Pathology and Survival of Patients Undergoing Total Cystectomy by Xingxing Tang, Yudong Cao, Jia Liu, Shuo Wang, Yong Yang, Peng Du

“…Only NLR (AUC=0.706, cut‐off value=3.12, sensitivity=75.00%, specificity=70.00%, P=0.014), dNLR (AUC=0.700, cut‐off value=2.49, sensitivity=66.67%, specificity=76.67%, P=0.015), and SII (AUC=0.704, cut‐off value=463.56, sensitivity=100.00%, specificity=40.00%, P=0.004) had a diagnostic value for lymph node metastasis. The median follow-up time was 31 months, and there was no significant difference in OS between the two groups for all IFs. …”
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Presenting a Model for Color Effectiveness in Marketing Using Consumer Neuroscience: A Sequential Exploratory Mixed-Methods Approach by Allahyar Ghasemi, Ahmad Rahchamani, Hamidreza Saeednia

“…MethodologyThe research methodology followed a sequential exploratory mixed method approach which included three phases: the first phase consisted of a qualitative study, the second phase was a quantitative characteristics study, and the last phase was the final quantitative laboratory study. …”
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Prediction of Distant Metastasis of Renal Cell Carcinoma Based on Interpretable Machine Learning: A Multicenter Retrospective Study by Dong J, Duan M, Liu X, Li H, Zhang Y, Zhang T, Fu C, Yu J, Hu W, Peng S

“…The presented model could help identify high-risk patients who require additional treatment strategies and follow-up regimens.Keywords: distant metastasis, machine learning, renal cell carcinoma, prediction, interpretable…”
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The effect of prone positioning on maternal haemodynamics and fetal wellbeing in the third trimester-A primary cohort study with a scoping review. by Laura Ormesher, Jessica Catchpole, Linda Peacock, Heather Pitt, Anastasia Fabian-Hunt, Dexter Hayes, Claudia Popp, Jason M Carson, Raoul van Loon, Lynne Warrander, Karli Büchling, Alexander E P Heazell

“…<h4>Methods</h4>Twenty-one women >28 weeks' gestation underwent non-invasive CO monitoring (Cheetah) every 5 minutes and continuous fetal heart rate monitoring (MONICA) in left lateral (20 minutes), prone (30 minutes), followed by left lateral (20 minutes). Anxiety and comfort were assessed by questionnaires. …”
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Multisectoral interventions for urban health in Africa: a mixed-methods systematic review by Meelan Thondoo, Ebele R. I. Mogo, Lambed Tatah, Monica Muti, Kim R. van Daalen, Trish Muzenda, Rachel Boscott, Omar Uwais, George Farmer, Adelaide Yue, Sarah Dalzell, Gudani Mukoma, Divya Bhagtani, Sostina Matina, Philip M. Dambisya, Kufre Okop, Charles Ebikeme, Lisa Micklesfield, Tolu Oni

“…The principle guiding the majority of the multisectoral interventions was community health equity (39.6%), followed by healthy cities and healthy urban governance principles (32.1%). …”
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Molecular, Cytogenetic, and Hematological Analysis of Chronic Myeloid Leukemia Patients and Discovery of Two Novel Translocations by Muhammad Asif, Abrar Hussain, Abdul Wali, Nazeer Ahmed, Irfan Ali, Zafar Iqbal, Muhammad Amir, Muhammad Shafiq, Mahmood Rasool

“…However, only 7 out of twenty-one patients exhibit BCR-ABL gene values≥1 after three months of follow-up when analyzed by the quantitative real-time PCR. …”
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Development of a horizontal transmission model to assess the effects of exposure to pathogenic E. cecorum during the hatching phase in broiler chickens by James Higuita, Marcela Arango, Aaron Forga, Mitch Rowland, Jundi Liu, Ross Wolfenden, Danielle Graham

“…CHROMagar™ Orientation agar was used to determine EC recovery followed by MALDI-TOF. The ANOVA was used to determine significant differences (P<0.05) for average body weight (BW) and average body weight gain (BWG) and EC quantification (Log10 CFU) with means being further separated using Student's t test. …”
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Rearing mealworm larvae with wheat, barley or maize grains as main source of nutrients in unbalanced or balanced substrates by D. Plonquet, G. Fondevila, M. Fondevila

“…In Experiment 2, feed intake (P < 0.001) and larval growth (P < 0.01) decreased in M2 compared to B2 and W2, which in turn showed similar growth performance to C2 (P < 0.001). Larval composition followed a similar trend in both experiments, with the highest N content observed in larvae fed C1 and C2 (P < 0.001), while DM and ether extract contents were higher in larvae reared on barley (P < 0.001). …”
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Therapy for Dupuytren’s Disease (II): Collagenase Therapy vs. Limited Fasciectomy—A Long-Term Comparative Study by Nikolaus Wachtel, Francesca Romana Dingler, Constanze Kuhlmann, Sinan Mert, Elisabeth Maria Haas-Lützenberger, Verena Alt, Nicholas Moellhoff, Riccardo Giunta, Wolfram Demmer

“…Methods: This monocentric retrospective study examined 35 patients who had been treated with bacterial collagenase for Dupuytren’s contracture, conducting a long-term follow-up after an average of 5.7 years. The results were compared to a control group of 40 patients treated with surgical limited fasciectomy on average 5.5 years ago. …”
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Public Health Discussions on Social Media: Evaluating Automated Sentiment Analysis Methods by Lisa M Gandy, Lana V Ivanitskaya, Leeza L Bacon, Rodina Bizri-Baryak

“…A comparison of Cohen κ values indicated that NLP tools (VADER, followed by LIWC’s tone and T2D) showed only fair agreement with manual coding. …”
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Eating difficulties among Nigerian community-dwelling stroke survivors: prevalence, correlates, and association with quality of life by Adekola B. Ademoyegun, Adebukola G. Ibitoye, Wasiu A. Rasaq, Oluwafunmilayo A. Adeniyi, David O. Fabuluje, Israel A. Ojo, Taofeek O. Awotidebe, Chidozie E. Mbada

“…Among the three types of EDs assessed, difficulty with energy/appetite (45.1%) was the most prevalent, followed by difficulty with ingestion (43.8%) and deglutition (40.8%). …”
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Smartphone-Based Intervention Targeting Norms and Risk Perception Among University Students with Unhealthy Alcohol Use: Secondary Mediation Analysis of a Randomized Controlled Tria... by Joseph Studer, John A Cunningham, Elodie Schmutz, Jacques Gaume, Angéline Adam, Jean-Bernard Daeppen, Nicolas Bertholet

“…The hypothesis is that PNF and PFR affect drinkers’ perceptions of drinking norms and risks, resulting in changes in drinking behaviors. This study is a follow-up mediation analysis of the primary and secondary outcomes of a randomized controlled trial testing the effect of a smartphone-based intervention to reduce alcohol use. …”
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A Multi‐Center Prospective Study on the Healing of Neuro‐Ischemic Ulcers in Singapore: A Prospective Cohort Study by Lingyan Meng, Priya Bishnoi, Zhiwen Joseph Lo, Enming Yong, Tze Tec Chong, David Carmody, Rajesh Babu Dharmaraj, Yi Zhen Ng, Keith Harding, Pei Ho

“…Each participant was followed up three times (1‐month, 3‐month and 6‐month after enrollment), with ulcer healing as the primary outcome of interest. …”
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IL-8 Downregulation Mediates the Beneficial Effects of Infection-Induced Fever on Breast Cancer Prognosis by Li H, Liang X, Ma J, Liu Q, Lin Y, Tang J, Ren Z, Liang Z

“…However, the key cytokines and the underlying mechanisms through which fever exerts its anti-tumor effects remain unclear.Patients and Methods: A total of 794 breast cancer patients were recruited between 2008 and 2017, with follow-up extending until October 31st, 2023. Infection-induced fever was assessed using questionnaires, while a multiplex assay evaluated a panel of 27 cytokines. …”
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In silico analysis of the effect of HCV genotype-specific polymorphisms in Core, NS3, NS5A, and NS5B proteins on T-cell epitope processing and presentation by Samina Baig, Samina Baig, Assel Berikkara, Ramsha Khalid, Syed A. Subhan, Tanveer Abbas, Syed Hani Abidi

“…PEP-FOLD was used to model selected epitopes, followed by peptide-HLA docking using HPEPDOCK. Finally, molecular dynamics simulations were conducted for 200 ns using Desmond software to analyze differences in HLA-epitope (from different HCV genotypes) interaction kinetics and dynamics.ResultsA total of 3,410, 8,054, 6,532, and 14,015 CTL epitopes were observed in the HCV Core, NS3, NS5A, and NS5B sequences, respectively. …”
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Effect of Vocational Rehabilitation Training Camp on Patients with Spinal Cord Injury Returning to Society by Lingjuan RAO, Li DAI, Li CHEN, Xiaoling LI, Jichao XIONG, Qingjun YANG, Huazhong YANG, Jinlong CUI

“…The statuses of returning to work of patients were followed up by telephone six months after discharge.Results:There were no statistically significant differences between the two groups in GSES scores and CIQ scores before treatment (<italic>P</italic>&gt; 0.05). …”
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Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world compar... by Rohan Khera, Yuan Lu, Harlan M Krumholz, Martijn J Schuemie, Ruijun Chen, George Hripcsak, Marc A Suchard, Patrick B Ryan, Anna Ostropolets

“…The study will pursue data-driven, large-scale propensity adjustment for measured confounding, a large set of negative control outcome experiments to address unmeasured and systematic bias.Ethics and dissemination The study ensures data safety through a federated analytic approach and follows research best practices, including prespecification and full disclosure of results. …”
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