Assessing the long-term economic impact of wheezing episodes after severe RSV disease in children from Argentina: a cost of illness analysis by Ranju Baral, Clint Pecenka, Elisabeth Vodicka, Andrea Rodríguez, Romina Libster, Julia Dvorkin, Emiliano M Sosa, Andrea Sancilio, Karina Dueñas, Carlos Rojas-Roque, Patricia B Carruitero, Fernando P Polack, Mauricio T Caballero

“…Costs were quantified in US dollars using the average exchange rate on the specific date of data collection.Results A total of 256 infants experienced severe RSV disease during their first year of life and were followed over a 5-year period in Buenos Aires. Overall, 150 children between 12 and 60 months presented 429 wheezing episodes. …”
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Influencing factors of acute kidney injury in elderly patients with diabetic nephropathy and establishment of nomogram model by Ganlin Wu, Ganlin Wu, Yanli Ye, Meirong Xu, Yanxia Zhang, Zuopeng Lu, Lv Huang

“…The prevalence and predisposing factors of acute kidney injury in diabetic nephropathy were analyzed, multivariate logistic regression were used to analyze the influencing factors of acute kidney injury in patients, and a nomogram risk prediction model was established based on risk factors for verification.ResultsAnalysis of the factors of acute kidney injury in diabetic nephropathy found that severe infection was the main trigger, accounting for 40.00%, followed by nephrotoxic antibiotics and severe heart failure. …”
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Long-Term Results of Medical and Surgical Methods for Elimination of the Internal Anal Sphincter Spasm in Chronic Anal Fissure (NCT03855046) by S. I. Achkasov, R. Yu. Khryukin, E. E. Zharkov, A. A. Ponomarenko, O. Yu. Fomenko, N. I. Klopkov, Z. Z. Kamaeva, E. Yu. Lebedeva, K. I. Sagidova

“…Long-term results of complex treatment were studied in 126 patients (54 (43 %) men and 72 (57 %) women), the median follow-up was 12.3 (12.2; 15.7) months. Statistical analysis was carried out in the program Statistica 13.3 (TIBCO Software Inc., USA).Results. …”
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Spectrum and trends of cancer among HIV patients in Southwestern Uganda. by Raymond Atwine, Mitala Yekosani, Abraham Birungi, Brian Ssenkumba, Barbra Tuhamize, Richard Ezinga, Keneth Male, Taseera Kabanda

“…Males were more likely to die (30/38 or 78.95%) and lost to follow-up (26/41 or 60.98%). Participants with baseline CD4 cell count > 200 cells/μl were more than twice likely to be active in care. …”
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Surgical interventions for degenerative cervical disease: Impact on patient quality of life, mental health, pain relief, and spiritual health by Ching-Ya Huang, Cheng-Shyuan Rau, Jo-Chien Lin, Shiun-Yuan Hsu, Ching-Hua Hsieh

“…Future research should include a more diverse sample, longer follow-up periods, and a combination of subjective and objective measures for a comprehensive assessment of outcomes.…”
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Mixed method study of feasibility and acceptability of electronic screening for measurement-based symptom monitoring of veterans accessing mental health treatment in VA community c... by Erin Almklov, Michael W. Lee, John D. Gault, Brian H. Blanco, Brian Huynh, Abigail Angkaw, Neal Doran, Niloofar Afari, James O. E. Pittman

“…Veterans received an eScreening link to complete an initial web-based assessment and three follow-up assessments spaced 4–6 weeks apart over the course of their treatment. …”
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Comparing the clinical efficacy of prostate enucleation by the Millin method and enucleation performed using a holmium laser (HoLEP) with a prostate volume more than 80 cm<sup>3</s... by S. N. Volkov, V. S. Stepanchenko, V. I. Tereshchenko, A. R. Dzharimok, O. R. Grigoryan, R. K. Mikheev

“…The data obtained during the operation in the early postoperative period, as well as the results of postoperative follow-up of patients were analyzed.Results. In the mid-term period, 4–6 months after surgery, patients from both groups were observed to improve their condition and reduce complaints of dysuric phenomena. …”
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Altered brain functional network connectivity and topology in type 2 diabetes mellitus by Weiwei Ni, Weiyin Vivian Liu, Mingrui Li, Shouchao Wei, Xuanzi Xu, Shutong Huang, Lanhui Zhu, Jieru Wang, Fengling Wen, Hailing Zhou

“…All participants underwent clinical, neuropsychological, and laboratory tests, followed by MRI examinations, including resting-state functional magnetic resonance imaging (rs-fMRI) and three-dimensional high-resolution T1-weighted imaging (3D-T1WI) on a 3.0 T MRI scanner. …”
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Development and effectiveness evaluation of an interactive e-learning environment to enhance digital health literacy in cancer patients: study protocol for a randomized controlled... by Lukas Lange-Drenth, Hellena Willemer, Mirjam Banse, Anke Ernst, Anne Daubmann, Anja Holz, Christiane Bleich, Susanne Weg-Remers, Holger Schulz

“…Two thirds of the 660 participants will be recruited through the German Cancer Information Service (CIS) and one third through non-CIS routes. Allocation will follow stratified randomization, accounting for recruitment route (CIS vs. non-CIS) and cancer type (breast cancer vs. other cancers), with variable block length. …”
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Photosynthetic characteristics of Paris polyphylla var. chinensis in response to different light intensities and soil water contents by Yaling Zhang, Yaling Zhang, Rong Xu, Rong Xu, Rong Xu, Zhaozhao Wang, Juan Zhang, Xinghao Tang, Yu Chen, Xiao-Li Yan, Lu-Ping Qu, Lu-Ping Qu

“…Considering the balance between growth rate and damage incidence, 50% shade should be the optimal treatment for P. polyphylla, followed by 30% and 70% shade. It was also observed that treatment with low soil water content (20%) significantly reduced Pn and LUE, while increasing stomatal conductance (gs) and water use efficiency (WUE). …”
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Prospects of two-port vitrectomy in the treatment of patients with epiretinal fibrosis by D.V. Borisova, I.A. Frolychev, N.A. Pozdeeva

“…Then, vitrectomy was performed according to the classical technique — the vitreous body was removed centrally, followed by membrane staining and membrane peeling, and partial tamponade with an air mixture. …”
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Genetic diversity and transmission pattern of multidrug-resistant tuberculosis based on whole-genome sequencing in Wuhan, China by Liqing Wei, Jun Chen, Zhen Deng, Zefang Zhang, Zhengbin Zhang, Qionghong Duan

“…Whole genome sequencing (WGS) was used to identify resistance-conferring mutations, examine their associations with specific Mycobacterium tuberculosis lineages or sublineages, and assess clustering profiles.ResultsAmong the 149 analyzed strains, the most prevalent mutations associated with resistance to 11 anti-tuberculosis drugs were identified as follows: rpoB Ser450Leu (59.73%, rifampicin), katG Ser315Thr (62.42%, isoniazid), embB Met306Val (42.86%, ethambutol), rpsL Lys43Arg (68.13%, streptomycin), pncA Trp68Arg (10.53%, pyrazinamide), gyrA Asp94Gly (22.50%, fluoroquinolones), and rrs 1401A &gt; G (50.00–100.00%, second-line injectable aminoglycosides). …”
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FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis by Yu Cheng, Yang Jiao, Wan Wei, Mengjia Kou, Yaodong Cai, Yang Li, Hao Li, Tonghua Liu

“…However, Feibi Recipe No. 2 (FBR2), a clinically validated traditional Chinese medicine formula, exhibits potential as an IPF treatment.ObjectiveThis study aimed to investigate the regulatory effect of FBR2 on ferroptosis through the SIRT3/p53 pathway and its therapeutic potential in improving IPF.MethodsPulmonary fibrosis was induced in C57BL/6J mice by intratracheal instillation of Bleomycin (BLM), followed by FBR2 treatment via gavage. Assessments encompassed histopathology, ELISA for cytokine detection, IHC and Western blot for protein expression analysis, and qRT-PCR for gene expression quantification. …”
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A Green Approach to Landfill Remediation: The Efficacy of Indigenous Zygophyllum coccineum L. and Leptadenia pyrotechnica L. in Phytoremediating a Heavy Oil Flay Ash-contaminated L... by Samir G.M. Al-Solaimani, Abdulrahman Alkurashi, Refaat A. Abohassan, Omer H.M. Ibrahim, Magdi A.A. Mousa

“…The sequence of heavy metal concentrations from highest to lowest in the roots and shoots was as follows: sulfur > aluminum > iron > zinc > manganese > nickel > chromium > vanadium > copper > cobalt. …”
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Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study by Christiane Pink, Birte Holtfreter, Henry Völzke, Matthias Nauck, Marcus Dörr, Thomas Kocher

“…Methods A total of 3047 participants from the prospective, population-based Study of Health in Pomerania (SHIP-START) were followed for a period of 13.0 ± 2.4 years. For the association between various inflammation/periodontitis measures and mortality, hazard ratios (HRs) were obtained from covariate-adjusted Cox proportional hazards models. …”
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RBM47 promotes cell proliferation and immune evasion by upregulating PDIA6: a novel mechanism of pancreatic cancer progression by Yihui Ma, Enjie Liu, Huijie Fan, Chenfei Li, Pei Huang, Meiying Cui, Zhengyang Wang, Jing Zhou, Kuisheng Chen

“…RBM47-RNA immunoprecipitation (RIP) followed by PCR and dual luciferase reporter assay were used to detect whether RBM47 could interact with the PDIA6 mRNA and how RBM47 would regulate the transcriptional activity of PDIA6, respectively. …”
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Clinical characteristics of Plasmodium vivax malaria infection in children and adolescents in the Republic of Korea during the period 2000 to 2016: a retrospective study by Jung Ah Lee, Je Eun Song, Seong Yeon Park, Yoon Soo Park, Yoonseon Park, Yee Gyung Kwak, Sang-Eun Lee, Hyun-Il Shin, Joon-Sup Yeom

“…In the ROK, the treatment regimen for pediatric P. vivax malaria involves oral administration of chloroquine at a dose of 25 mg base/kg divided over 3 days, followed by primaquine at a dose of 0.3 mg/kg for 14 days. …”
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Hard and soft tissue alterations after the application of different soft tissue grafting materials during immediate dental implant placement: a systematic review and Bayesian netwo... by Ali Azadi, Fatemeh Rezaei, Atoosa Yazdani, Kimia Hejazi, Aryousha Moallem Savasari, Reza Amid, Mahdi Kadkhodazadeh

“…The pink esthetic score (PES), marginal interproximal bone level changes (MIBL), buccal bone thickness changes (BBT), keratinized tissue width changes (KTW), soft tissue thickness changes (STT), papilla height changes (PH), midfacial gingival margin level changes (MGML) were defined as desired outcomes of the study; except for the MIBL with 12 – 24 months of follow-up, 6 – 12 months is considered for other outcomes. …”
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Perbandingan Daya Hambat Larutan Antiseptik Povidone iodine dengan Ekstrak Daun Sirih terhadap Candida albicans secara In Vitro by Septriana Putri, Aziz Djamal, Rahmatini , Cimi Ilmiawati

“…Betel leaf extract at concentration of 5% and 10% did not have inhibitory effectwhile betel leaf extract at concentration of 20% had<br />inhibitory effect on C. albicans. Analysis by ANOVA followed by Post-hoc tests showed a significant difference in inhibitory activity of povidone iodine and betel leaf extract at 20% concentration compared to control (p &lt; 0,05). …”
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CHANGE IN TESTOSTERONE LEVELS IN ENDOSCOPIC OPERATIONS ON THE PROSTATE GLAND by E. A. Efremov, S. Yu. Shekhovtsov, D. S. Merinov, A. O. Butov, Yu. V. Kastrikin, T. I. Garaev

“…All patients were divided into 3 groups: Group I (14 patients) – patients with a normal preoperative level of testosterone (above 12 nmol/L), IIA group (17 patients) – patients with preoperative testosterone deficiency receiving HRT 2 weeks before surgery and during the entire period of postoperative follow-up and IIB group (16 patients) – patients with preoperative testosterone deficiency who did not receive therapy. …”
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