Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyo... by Zhen Qiu, Yuhong He, Hao Ming, Shaoqing Lei, Yan Leng, Zhong-yuan Xia

“…H9C2 cardiomyocytes were exposed to HG (30 mM) condition with or without LPS, along with caspase-1 inhibitor (Ac-YVAD-CMK), inflammasome inhibitor (BAY11-7082), ROS scavenger N-acetylcysteine (NAC), or not for 24 h, then subjected to 4 h of hypoxia followed by 2 h of reoxygenation (H/R). The cell viability, lactate dehydrogenase (LDH) release, caspase-1 activity, and intracellular ROS production were detected by using assay kits. …”
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Preparation and Anti-fatigue Function of Weizmannia coagulans BC99 Emergency Energy Bar by Haodan GUO, Ying WU, Yuqiong WEI, Li CAO, Zhouya BAI, Qiuxia FAN, Nan PENG, Shaobin GU

“…Results: The optimal conditions of the probiotic energy bar sandwich were as follows: 35 g of nuts, 45 g of oats, 15 g of chia seeds, syrup composite ratio (Wmaltose:Wwhite granulated sugar) of 2.0, and stirring time of 9.0 minutes. …”
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Acute kidney injury recovery status predicts mortality and cardiorenal outcomes in patients admitted with acute decompensated heart failure by Kavitha Muthiah, Christopher Hayward, James Chong, Kirsty Pringle, Shehane Mahendran, Albert Vien, Sumita Barua, Sanjay Chavali, David Makarious, Phillip Lo

“…Event-free survival analysis was performed to predict death and cardiorenal outcomes at hospital discharge and 6-month follow-up. Multinomial logistic regression was performed to identify predictors of ongoing AKI. …”
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Distribution characteristics of blood group antigen and susceptibility in patients with pulmonary tuberculosis by JU Min, LIU Bin, GONG Xiaoyan, LIN Guoyue

“…Among them, the Uyghur ethnicity has the highest frequency at 4.44%, followed by Kazakh at 2.13%, Hui at 1.26%, Han at 0.58%, with significant differences(P<0.05). …”
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A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores by Vasanop Vachiramon, Sonphet Chirasuthat, Suphagan Boonpethkaew, Nawara Sakpuwadol, Tanat Yongpisarn, Natthachat Jurairattanaporn

“…The results showed that both sides exhibited a reduction in pore volume and skin roughness over time, but the side treated with onaBoNT-A monotherapy had a slightly better improvement than the combination side at the 6-month follow-up. Subjects with histories of facial oiliness were more likely to respond to onaBoNT-A monotherapy, while those without histories of facial oiliness were more likely to respond to the side treated with combined treatment. …”
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Report on the Academic Symposium: Youth Quotas − The Answer to Changes in Age Demographics? by Igor Dimitrijoski

“…Can young people really be relied upon to represent the interests of the young generation as a whole, or will they just follow their own individual interests? Are youth quotas in general an effective instrument to strengthen the rights of the young generation or do we need other and more effective instruments? …”
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Impact of Postshock Transcutaneous Pacing on Chest Compression Quality during Resuscitation: A Simulation-Based Pilot Study by Wojciech Telec, Tomasz Kłosiewicz, Radosław Zalewski, Julia Żukowska-Karolak, Artur Baszko, Mateusz Puślecki

“…Successful defibrillation is commonly followed by a transient nonperfusing state. To provide perfusion in this stagnant phase, chest compressions are recommended irrespective of arrhythmia termination. …”
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Association between occupational exposure to gasoline and anemia: a retrospective cohort study in China by Lan Lin, Hongmei Cao, Beining Wu, Jin Wang, Lin Song, Weiling Chan, Geyang Li, Li Zhou, Jing Xiao, Lejia Zhu, Yulong Lian

“…Participants were enrolled in 2013–2015, and follow-up in 2019. Anemia was diagnosed according to WHO guidelines on hemoglobin cutoffs to define anemia in individuals and populations. …”
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Exploring the upper ocean characteristics of a bay using coastal and regional ocean community model by D. Jaishree, P.T. Ravichandran

“…Including a three-year spin-up phase facilitated the adjustment of the model to initial conditions and the attainment of equilibrium, ensuring its fidelity to real-world conditions. The follow-up analyses and comparisons were performed five years after the spin-up phase. …”
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Modulation of Acupuncture at Quchi (LI 11) and Waiguan (SJ 5) acupoints on LTP-like Plasticity by Qianqian SUN, Guo YU, Huitian ZHANG, Xiaokuo HE

“…We used three laser pens to locate and mark with a soft-tipped pen to assure a constant placement of the coil throughout the session.②Detection of resting motor threshold (rMT): The response resting motor threshold (rMT) was defined as the stimulus intensity at which 5/10 consecutive single stimuli at the optimal sclap site evoked a MEP of at least 50 μV amplitude in the relaxed muscle.③Investigate the short-latency somatosensory-evoked potentials (SLSEP): Monophasic electrical stimulation adjusted to produce visible thumb twitch was delivered at points overlying the ulnar nerve at the right of FDI, through a bipolar electrode (cathode proximal) with intensity 5-10 mA.④Brain plasticity induced by PAS-LTP: The LTP-like plasticity induced by paired associative stimulation (PAS) consisted of 200 stimulus pairs of electrical stimulation followed by TMS. Subjects would be tested 8 times for about 80 minutes each time. …”
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Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur... by Lihua Huang, Liuliu He, Qingfeng Zeng, Jinjing Huang, Xiaoyan Luo, Qiuming Zhong

“…Hazard ratios (HR) and 95% confidence intervals (CIs) for all-cause and CVD mortality were calculated using weighted Cox proportional hazards and restricted cubic spline models.ResultsAmong the 1,931 participants (mean [SE] age, 73.2 [0.2] years; 61.9% female), over a median follow-up period of 7.6 years, a total of 1,003 deaths were observed, including 412 from CVD. …”
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Sociodemographic characteristics and longitudinal progression of multimorbidity: A multistate modelling analysis of a large primary care records dataset in England. by Sida Chen, Tom Marshall, Christopher Jackson, Jennifer Cooper, Francesca Crowe, Krish Nirantharakumar, Catherine L Saunders, Paul Kirk, Sylvia Richardson, Duncan Edwards, Simon Griffin, Christopher Yau, Jessica K Barrett

“…<h4>Methods and findings</h4>We utilised electronic primary care records from 13.48 million participants in England, drawn from the Clinical Practice Research Datalink (CPRD Aurum), spanning from 2005 to 2020 with a median follow-up of 4.71 years (IQR: 1.78, 11.28). The study focused on 5 important chronic conditions: cardiovascular disease (CVD), type 2 diabetes (T2D), chronic kidney disease (CKD), heart failure (HF), and mental health (MH) conditions. …”
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CHA2DS2-VASc Score Is Associated With Prognosis in Patients With Acute Ischemic Stroke Without Atrial Fibrillation by Mingjuan Song, MM, Xu Chen, MD

“…Results: The rate of MACE during 12-month follow-up was statistically significantly higher (P < .01) in patients with a CHA2DS2-VASc score greater than 2 (34.7%) than in patients with a score of 2 (23.9%) or of 0 or 1 (14.8%). …”
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Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis by Tim Salinger, Kai Hu, Dan Liu, Scharoch Taleh, Sebastian Herrmann, Daniel Oder, Daniel Gensler, Jonas Müntze, Georg Ertl, Kristina Lorenz, Stefan Frantz, Frank Weidemann, Peter Nordbeck

“…A total of 402 patients (mean age 78 ± 9.4 years, 58% males) were included in the study. Mean follow-up duration was 3.4 ± 1.9 years. The average number of cardiac comorbidities and risk factors was 3.1 ± 1.6. …”
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Klotho enhances stability of chronic kidney disease atherosclerotic plaques by inhibiting GRK2/PLC-β-mediated endoplasmic reticulum stress in macrophages via modulation of the ROS/... by Zhe Li, Jing Li, Lin Li, Qian Wang, Qian Zhang, Ling Tian, Chenchen Li

“…Western blotting detected associated protein expression, followed by cell-based experiments for validation. …”
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From Peril to Protection: an evaluation of regulations impacting eScooter injuries by Leslie M Kobayashi, Todd W Costantini, Jay J Doucet, Jarrett E Santorelli, Laura N Haines, Kendra M Black

“…The average age was 38.6 years; 45+ years was the most common age group at 33%, followed by ages 25–34 (31%). The mean ISS was 9±6, with ISS 0–9 (65.1%), 10–15 (24.4%), 16–24 (8.4%), and &gt;25 (20.1%). …”
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Lifestyle risk factors for overweight and obesity among rural Indian adults: a community-based prospective cohort study by Rajesh Kumar Rai, Sabri Bromage, Jan-Walter De Neve, Anamitra Barik

“…To address this evidence gap, this study used cohort data (baseline: 2018–19, follow-up: 2022–23) from the Birbhum Population Project (West Bengal, India) to analyse lifestyle risk factors and their association with incidence and remission of overweight/obesity among adults aged ≥18 years (sample: 8,974). …”
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Spatial-Temporal Changes and Influencing Factors of Regional Technological Innovation Efficiency in China: A Three Entity Comparative Perspective by Ye Lei, Zhang Ting, Cao Xianzhong, Zeng Gang

“…The main findings are as follows: 1) The technological innovation efficiencies of firms, universities, and research institutes show a steady increase over the study period, with a 45%-55% improvement space. …”
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Triglyceride-glucose index predicts adverse cardiovascular events in patients with H-type hypertension combined with coronary heart disease: a retrospective cohort study by Changjiang Li, Shun Zhao, Yingkai Li, Songyuan He, Wen Jian, Yanci Liu, Zichao Cheng, Hongyu Peng

“…Results A total of 546 patients were included, with a median follow-up time of 39.00 ± 0.69 months, and 73 MACEs occurred, with higher tertiles of the TyG index associated with a higher cumulative risk of MACEs (log-rank, P = 0.001). …”
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Owners’ perceptions of dog treat management in Western Romania by Sorana Daina, Anamaria Blaga-Petrean, Silvana Popescu, Ioana Delia Pop, Daniel Mierlita, Adrian Macri

“…Emotional attachment was the primary motivation for providing treats (52%), followed by perceived health benefits (35%) and training purposes (25%). …”
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