Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators by S. Ali Naqvi, Graham C. Thompson, Ari R. Joffe, Jaime Blackwood, Dori-Ann Martin, Mary Brindle, Herman W. Barkema, Craig N. Jenne

“…We used multivariate regression analysis to evaluate the seven target proteins, followed by decision tree and heat mapping analyses for all proteins evaluated. …”
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Alcohol Relapse After Liver Transplantation: Risk Factors, Outcomes, and a Comparison of Risk Stratification Models by Karen Young, Yuval A. Patel, Benson Hoffman, Sarah Peskoe, Shein-Chung Chow, Karli Erhart, Jennifer Jackson, Stephanie Garbarino

“…Results: Sixty-seven patients with a median follow-up time of 43 months were included. Eighteen (27%) experienced alcohol relapse. …”
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CYSTIC DEGENERATION OF THE DUODENUM ASSOCIATED WITH CHRONIC PANCREATITIS by A. G. Kriger, A. V. Smirnov, S. V. Berelavichus, D. S. Gorin, N. N. Vetsheva, Ja. I. Nerestjuk, D. V. Kalinin, A. V. Glotov

“…Long-term results of surgical treatment were evaluated in 47 patients with a median follow-up was 49.9 months.Results. Histological examination resulted that in 69.9% of DD was related with groove pancreatitis, with ectopic pancreatic tissue – in 30.1%. …”
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Artificial Intelligence–Powered Training Database for Clinical Thinking: App Development Study by Heng Wang, Danni Zheng, Mengying Wang, Hong Ji, Jiangli Han, Yan Wang, Ning Shen, Jie Qiao

“…For diseases, pneumonia was the most frequently learned, followed by cholecystolithiasis (n=216, 14.1%), benign prostate hyperplasia (n=196, 12.8%), and bladder tumor (n=193, 12.6%). …”
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Elucidating the role of precipitated phase particles in modifying creep properties of as-cast Mg-Bi/Sn-based alloys by Gang Xu, Wei-li Cheng, Yi-hao Luo, Hui Yu, Li-fei Wang, Hang Li, Hong-xia Wang, Jin-hui Wang

“…The results suggested that the creep properties followed the order of BTMQ5500 > TMQ1000 > BMQ1000. …”
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Relationship between physical activity during pregnancy and maternal health outcomes: evidence from the MAASTHI cohort study in Bengaluru, India by Yamuna Ana, Floor A. van den Brand, Onno C. P. van Schayck, Giridhara R. Babu

“…We used linear logistic regression to assess the association between a continuous measure of physical activity level and maternal outcomes and performed multivariable logistic regression analysis to understand the association between sedentary behavior and maternal health outcomes and mode of delivery after adjusting for potential confounders.ResultsWe interviewed 2,424 eligible pregnant women at baseline and 1,317 were considered in the final analysis after excluding those who missed follow-ups. We observed that one unit increase in physical activity level was associated with reduced prenatal depressive symptoms (β = −6.36, p < 0.001), fasting (β = 2.06, p = 0.04), and postprandial blood sugar levels (β = −0.99, p = 0.01), respectively. …”
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Functional Evaluation of Open Carpal Tunnel Release in Carpal Tunnel Syndrome Patients by Swagat Mahapatra, Devta Singh, Prakhar Mishra, Jaydeep Patel, Madhusudan Mishra, Animesh Gupta

“…The majority of the studied cases were female (77.6%), followed by males (22.4%). In the majority of cases, the right hand was the dominant hand (58.7%), and also, the right hand was the most operated hand (55.1%). …”
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Murine DX5+NKT Cells Display Their Cytotoxic and Proapoptotic Potentials against Colitis-Inducing CD4+CD62Lhigh T Cells through Fas Ligand by Jens M. Werner, Michael Damian, Stefan A. Farkas, Hans J. Schlitt, Edward K. Geissler, Matthias Hornung

“…CD4+CD62Lhigh and DX5+NKT cells from the spleen of Balb/c mice were isolated first by MACS, followed by FACS sorting and cocultured for up to 96 h. …”
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Association between triglyceride glucose index and adverse cardiovascular prognosis in patients with atrial fibrillation without diabetes: a retrospective cohort study by Aobo Gong, Ying Cao, Zexi Li, Wentao Li, Fanghui Li, Yao Tong, Xianjin Hu, Rui Zeng

“…The MACE risk in the middle Tyg group was similar to that in the low Tyg group (P = 0.1) during the 48-month follow-up period. However, focusing on the last 24 months revealed a higher MACE risk (P = 0.015) in the middle Tyg group. …”
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Sequence-based GWAS in 180,000 German Holstein cattle reveals new candidate variants for milk production traits by Ana-Marija Križanac, Christian Reimer, Johannes Heise, Zengting Liu, Jennie E. Pryce, Jörn Bennewitz, Georg Thaller, Clemens Falker-Gieske, Jens Tetens

“…For that purpose, 180,217 cattle were imputed to the sequence level and large-scale genome-wide association study (GWAS) followed by fine-mapping and evolutionary and functional annotation were carried out to identify and prioritize new association signals. …”
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Developing a patient-centered measure to assess food-related and nutrition-related quality of life in patients with cancer by Seth Berkowitz, Mackenzie Kemp, Sara Beachy, Karla Martin, Brooke Worster, Richard W Hass, Iyaniwura Olarewaju, Kristin L Rising

“…Validity and internal consistency of the FN-QoL measure were evaluated with bivariate correlation matrices and Cronbach’s alpha followed by a multiple linear regression analysis.Results 117 individuals completed the survey: mean age 62 (21–90), 49.6% white, 58.3% women. …”
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An Investigation of the Capabilities of Resin Tire Carbon Black “N-330” as a Waste Binder in Asphalt Concrete Mixtures by Amr. A. Nada, Walid Fouad Edris, Hebah Mohammad Al-Jabali, Ahmed D. Almutairi, Abd Al-Kader A. Al Sayed, Shady Khairy

“…The testing program involved the preparation of asphalt concrete specimens using a Marshall mix design, followed by a Marshall Stability test to evaluate the deformation resistance of the modified mixtures. …”
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Association of live microbes intake and risk of all-cause, cardiovascular disease, and cancer-related mortality in patients with chronic kidney disease by Debin Chen, Yongju Ye, Yining Li, Erxu Xue, Qijun Zhang, Youlan Chen, Jianhui Zhao

“…This study aims to investigate the association between dietary intake of live microbes and long-term health outcomes among individuals with CKD.Methods Utilizing the National Health and Nutrition Examination Survey (NHANES) database, Cox regression analysis assessed the association between medium and high categories dietary live microbe intake and health outcomes (all-cause, cardiovascular disease [CVD], and cancer-related mortality) in CKD patients.Results A total of 3,646 CKD patients were enrolled. During the follow-up period, 1,593 all-cause mortality events were recorded, including 478 CVD deaths and 268 cancer deaths. …”
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Malignant transformation of proliferative Verrucous Leukoplakia—systematic review & meta-analysis by Khadijah Mohideen, Snehashish Ghosh, Chandrasekaran Krithika, Mutaz Ali-Hassan, Revant Chole, Safal Dhungel

“…Results Among 998 articles, 53 met inclusion criteria, covering 1159 PVL patients, with 48.4% experiencing malignant transformation over an average 6.28 ± 3.73—year follow-up. Most cases had low or moderate bias risk. …”
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Elucidating the Role of HIF-1α/YAP Signaling Pathway in Regulating Inflammation in Human Periodontal Stem Cells: An in vitro Study by Zhao HW, Liu ST, Wang XJ, Zhang XM, Ma X

“…This study investigated the effects of the prolyl hydroxylase (PHD) inhibitor DMOG on pro-inflammatory cytokine expression in human periodontal ligament stem cells (hPDLSCs) and examined the involvement of the HIF-1α/YAP signaling path ay in modulating inflammation.Materials and Methods: hPDLSCs were cultured and treated with lipopolysaccharide (LPS) to induce inflammation, followed by DMOG treatment. Cell proliferation was assessed using the CCK-8 assay, while ELISA and RT-qPCR evaluated the expression levels of HIF-1α, IL-1β, TNF-α, and YAP. …”
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The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial by Sun YY, Wang ML, Zhao RH, Hao MY, Song S, Zhou Y, Zhang N

“…Patients will undergo clinical symptom assessments and cranial fMRI scans at baseline (− 1– 0 weeks), post-treatment (4 weeks), and at the follow-up (16 weeks). Forty healthy subjects will be recruited for observation, with a single MRI scan conducted only at baseline (− 1– 0 week). …”
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Role of serum sodium on heart, anemia, and diabetes patients by Mahashweta Das, Sunit Kumar Medda, Shipra Banik, Rabindra Nath Das

“…., ANS*DEE (P = 0.0009); age and time to follow-up (TTF), i.e., AGE*TTF (P = 0.0700); age and serum creatinine (SEC), i.e., AGE*SEC (P = 0.0901); EJF and SEC, i.e., EJF*SEC (P = 0.0044); and CRP and TTF, i.e., CRP*TTF (P = 0.0021). …”
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Altered circadian rhythmicity of the QT interval predicts mortality in a large real-world academic hospital population by Rutger R. van de Leur, Bastiaan C. du Pré, Markella I. Printezi, Rutger J. Hassink, Pieter A. Doevendans, René van Es, Linda W. van Laake

“…Objective and rationale: Small studies have shown that the QT interval follows a circadian rhythm. This finding has never been confirmed in a large real-world hospital population and the clinical meaning of disrupted rhythmicity remains unknown. …”
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Assessing and optimizing the potential for climate change mitigation and carbon sequestration in urban residential green spaces: energizing sustainable cities by Hancheng Liu, Jialong Zhang, Zijun Wang

“…In terms of daily carbon sequestration per unit canopy projection area, the ranking was as follows: evergreen trees > evergreen shrubs > deciduous trees > deciduous shrubs. …”
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Sociodemographic and lifestyle predictors of incident hospital admissions with multimorbidity in a general population, 1999–2019: the EPIC-Norfolk cohort by Kay-Tee Khaw, Robert Luben, Shabina Hayat, Nicholas Wareham, Paul P Pharoah

“…We aimed to explore the independent associations for a range of demographic, lifestyle and physiological determinants and the likelihood of subsequent hospital incident multimorbidity.Methods We examined incident hospital admissions with multimorbidity in 25 014 men and women aged 40–79 in a British prospective population-based study recruited in 1993–1997 and followed up until 2019. The determinants of incident multimorbidity, defined as Charlson Comorbidity Index ≥3, were investigated using multivariable logistic regression models for the 10-year period 1999–2009 and repeated with independent measurements in a second 10-year period 2009–2019.Results Between 1999 and 2009, 18 179 participants (73% of the population) had a hospital admission. …”
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