Comprehensive evaluation of the properties of camel bone gelatin: impact of the duration of pre-treatment and extraction by Meriem Imelhayene, Abdelkader Adamou, Samira Becila, Ayad Redjeb, Dahia Saidj, Abdelhakim Senoussi, Dimitris Sarris, Eleni Naziri

“…The gelatin extraction process comprised demineralization with hydrochloric acid, followed by pre-treatment with sodium hydroxide for 24 or 48 hours and subsequent chemo-thermal extraction in acetic acid for 6 or 12 hours. …”
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Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids by Xin-Ru Wen, Jia-Wei Tang, Jie Chen, Hui-Min Chen, Muhammad Usman, Quan Yuan, Yu-Rong Tang, Yu-Dong Zhang, Hui-Jin Chen, Liang Wang

“…Vaginal fluid samples were classified as BV positive or BV negative using the BVBlue Test and clinical microscopy, followed by SERS spectral acquisition to construct the data set. …”
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Lipid Levels and Lung Cancer Risk: Findings from the Taiwan National Data Systems from 2012 to 2018 by Jung-Yueh Chen, Nai-Hui Chi, Ho-Shen Lee, Chia-Ni Hsiung, Chang-Wei Wu, Kang-Chi Fan, Meng-Rui Lee, Jann-Yuan Wang, Chao-Chi Ho, Jin-Yuan Shih

“…For patients who developed lung cancer during follow-up, a 1:2 control group of nonlung cancer participants was selected after matching. …”
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East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol by Michael Doherty, Roshan das Nair, Ana Valdes, Reuben Ogollah, Paul Greenhaff, Bonnie Millar, Michelle Hall, Amy Fuller, Polykarpos Angelos Nomikos, David A Walsh, A Abhishek

“…We will compare three groups: group A will receive the non-pharmacological components delivered before pharmacological components; group B will receive pharmacological components followed by the non-pharmacological components; and group C (control arm) will continue to receive usual care. …”
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Disparities in stage at diagnosis of head and neck tumours in Brazil: a comprehensive analysis of hospital-based cancer registriesResearch in context by Flávia Nascimento de Carvalho, Marianna de Camargo Cancela, Luciano Mesentier da Costa, Luís Felipe Leite Martins, Fernando Luiz Dias, Dyego Leandro Bezerra de Souza, Luis Felipe Ribeiro Pinto

“…The highest percentage of advanced-stage tumours were hypopharyngeal [91.3% (10,186/11,159)], followed by oropharyngeal [86.6% (28,578/32,991)], oral cavity [75.1% (27,121/36,120)], and laryngeal cancer [69.5% (24,382/35,101)]. …”
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Radiological and Clinical Features and Outcomes of Patients with Primary Pulmonary Salivary Gland-Type Tumors by Xiaoyu Han, Jianchu Zhang, Jun Fan, Yukun Cao, Jin Gu, Heshui Shi

“…The main presenting symptom of SGT was cough (56.3%), followed by dyspnea (40.6%), associated with the tumor location. …”
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Helicobacter pylori infection promotes M1 macrophage polarization and gastric inflammation by activation of NLRP3 inflammasome via TNF/TNFR1 axis by Xiao Fei, Sihai Chen, Leyan Li, Xinbo Xu, Huan Wang, Huajing Ke, Cong He, Chuan Xie, Xidong Wu, Jianping Liu, Yong Xie, Nonghua Lu, Yin Zhu, Nianshuang Li

“…Results Single-cell RNA sequencing (ScRNA-seq) analysis of human gastric tissues, followed by validation, indicated that NLRP3 was primarily expressed in myeloid cells and was significantly increased in H. pylori-positive gastritis compared to H. pylori-negative gastritis. …”
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Triglyceride to high density lipoprotein cholesterol ratio and major adverse cardiovascular events in ACS patients undergoing PCI by Shangxun Zhou, Miaohan Qiu, Kexin Wang, Jing Li, Yi Li, Yaling Han

“…Survival analysis, Cox regression analysis and restricted cubic spline (RCS) were employed to assess the associations between TG/HDL-C ratio and the risk of major adverse cardiovascular events (MACE), all-cause death, cardiac death and all-cause bleeding events. Over a 12-month follow-up period, 638 (3.9%) patients experienced MACE while 2837 (16.1%) patients experienced bleeding events. …”
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Immunization with a Synthetic Helicobacter pylori Peptide Induces Secretory IgA Antibodies and Protects Mice against Infection by David Espinosa-Ramos, Diana Caballero-Hernández, Ricardo Gomez-Flores, Armando Trejo-Chávez, Luis Jerónimo Pérez-Limón, Myriam Angélica de la Garza-Ramos, Reyes Tamez-Guerra, Patricia Tamez-Guerra, Cristina Rodriguez-Padilla

“…For this, mice received an intraperitoneal injection of 100 μg of H. pylori peptide on the first week, followed by two weekly subcutaneous reinforcements and further 109 bacteria administration in the drinking water for 3 weeks. …”
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Perioperative nursing based on enhance recovery after surgery for pediatric patients undergoing modified artificial partial knee-joint prosthesis replacement for osteosarcoma aroun... by NONG Yuanxia (农源夏), CHEN Jian (陈剑), YANG Shuyun (杨舒云)

“…All pediatric patients were followed up and recovery with good walking posture. …”
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Using machine learning to predict patients with polycystic ovary disease in Chinese women by Chen-Yu Wang, Dee Pei, Chun-Kai Wang, Jyun-Cheng Ke, Siou-Ting Lee, Ta-Wei Chu, Yao-Jen Liang

“…Conclusion: Mach-L methods overtook conventional LR and age was the most significant factor, followed by TG, GPT, WBC, UA, and Plt in a cohort of Chinese women.…”
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Continuous Glucose Monitoring in Women with Normal OGTT in Pregnancy by Linda Tartaglione, Enrico di Stasio, Angelo Sirico, Mauro Di Leo, Salvatore Caputo, Alessandro Rizzi, Agnese Caneschi, Sara De Carolis, Dario Pitocco, Antonio Lanzone

“…After evaluation of one week of SMBG, 21 required diet therapy and 12 required insulin treatment and were followed until the delivery. An increase in gestational weight gain was observed in normal women with normal OGTT but this was not significant. …”
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Effect of antiretroviral therapy on the mortality of HIV-1 infection long-term non-progressors: a cohort study by Jinming Su, Jie Liu, Fengxiang Qin, Rongfeng Chen, Tongxue Qin, Xing Tao, Xiu Chen, Wen Hong, Bingyu Liang, Ping Cui, Li Ye, Junjun Jiang, Hao Liang

“…Methods Eligible LTNP and typical progressors (TP) were recruited in Guangxi by December 2018. Participants were followed up until December 2022, monitoring ART status, CD4+ T cell counts, and survival/death outcomes. …”
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Prognostic Significance of Chronic Kidney Disease (CKD-EPI Equation) and Anemia in Patients with Chronic Heart Failure Secondary to Chagas Cardiomyopathy by Marcelo Arruda Nakazone, Maurício Nassau Machado, Ana Paula Otaviano, Ana Maria Silveira Rodrigues, Augusto Cardinalli-Neto, Reinaldo Bulgarelli Bestetti

“…At baseline, 98 individuals (42.2%) had criteria for CKD and 41 (17.7%) for anemia. During follow-up, 136 patients (58.6%) died. Independently, CKD and anemia were not associated with all-cause mortality. …”
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Concentration-dependent interactive toxicity of cadmium and mercury: Non-negligible effects on phytoremediation by indigenous Artemisia lavandulaefolia by Gangyang Zhang, Guo Chen, Rui Yang, Chunlian Bai, Weiyuhao Yang, Juan Zhang, Xuyang Yin, Fang Yang, Chandra Shekhar Seth, Haitao Liu

“…With increasing Hg, plants preferred to stimulate belowground antioxidant activity, whereas high concentrations of Cd followed the opposite trend. This study provides a theoretical basis for the phytoremediation of this species under combined heavy metal pollution. …”
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Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review by Zhigao Huang, Zhuo Liu, Lin Zhuo, Xin Ma, Zhenbin Jiang, Kewei Chen, Jiyuan Chen, Yuxuan Li, Guoliang Wang, Xiaojun Tian, Hongxian Zhang, Lei Liu, Lulin Ma, Kai Hong, Shudong Zhang

“…Methods A systematic search using PubMed, Embase, Web of Science, the Cochrane Library and European Urology databases was conducted. Study selection followed the PRISMA guidelines. After screening, eleven articles and abstracted fully compatible with the PICOS were included in this systematic review. …”
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Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis by Vinzenz Fleischer, Tobias Brummer, Muthuraman Muthuraman, Muthuraman Muthuraman, Falk Steffen, Milena Heldt, Maria Protopapa, Muriel Schraad, Gabriel Gonzalez-Escamilla, Sergiu Groppa, Stefan Bittner, Frauke Zipp

“…Here, we aimed to investigate the prognostic value of single and multimodal biomarker combinations to predict four-year disability progression in patients with MS.MethodsIn total, 111 MS patients were followed up for four years to track disability accumulation based on the Expanded Disability Status Scale (EDSS). …”
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Classifying problematic gaming using a latent profile approach based on personality traits in Chinese young adolescent by Jingyue Hao, Zhenjiang Liao, Qiuping Huang, Xinxin Chen, Shuhong Lin, Yongyan Shi, Yifan Li, Yin Tang, Xuhao Wang, Hongxian Shen

“…LPA was applied to identify distinct user groups, followed by an examination of associations between profile membership and auxiliary variables. …”
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Typical and Local Diagnostic Reference Levels for Chest and Abdomen Radiography Examinations in Dubai Health Sector by Entesar Z. Dalah, Maitha M. Al Zarooni, Faryal Y. Binismail, Hashim A. Beevi, Mohammed Siraj, Subrahmanian Pottybindu

“…The LDRL values defined per chest and abdomen projection for the weight band group (60–80 kg) were as follows: chest—0.51 PA, 2.46 AP, and 2.13 LAT dGy·cm²; abdomen—8.08 for erect and 5.95 for supine dGy·cm². …”
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Does tocilizumab eliminate inflammation in GCA? A cohort study on repeated temporal artery biopsies by Chiara Marvisi, Francesco Muratore, Carlo Salvarani, Pierluigi Macchioni, Pamela Mancuso, Luigi Boiardi, Stefania Croci, Paolo Giorgi Rossi, Alberto Cavazza, Annibale Versari, Rexhep Durmo, Caterina Ricordi, Martina Bonacini, Giuseppe Malchiodi

“…We aimed to evaluate the histological impact of adding tocilizumab (TCZ) to GCs.Methods We enrolled all consecutive GCA patients with an inflammed TAB at diagnosis who were treated with TCZ and GCs for ≥6 months and followed from December 2017 to December 2023. Within 2 weeks, all patients underwent a second TAB, positron emission 18-fluorodeoxyglucose tomography/CT (PET/CT) and vessel colour Doppler ultrasonography (CDUS). …”
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