The prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in colorectal cancer and colorectal anastomotic leakage patients: a retrospe... by Nuo Xu, Jian-Xin Zhang, Jia-Jie Zhang, Zhuo Huang, Lian-Chun Mao, Zhi-Yong Zhang, Wei-Dong Jin

“…Results A total of 890 patients with colorectal cancer, 102 patients with CAL, and 788 patients with non- anastomotic leakage (AL) colorectal cancer were enrolled for a median follow-up of 96 months (quartile range 33–133). In this study, COX regression analysis showed that preoperative NLR and PLR could predict the prognosis of CAL patients, and the optimal cut-off points of NLR and PLR were 2.89 and 157.62, respectively. …”
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Self-administered active versus sham acupressure for diarrhea predominant irritable bowel syndrome: a nurse-led randomized clinical trial by Maha Gamal Ramadan Asal, Ahmed Abdelwahab Ibrahim El-Sayed, Samira Ahmed Alsenany, Zahraa Hassan Ramzy, Rasha Fathy Ahmed Dawood

“…Both groups underwent two days of training, followed by four weeks of intervention. The active group applied pressure to specific therapeutic acupoints, while the sham group used non-therapeutic points. …”
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Atherogenic Index in Type 2 Diabetes and Its Relationship with Chronic Microvascular Complications by Zhen Li, Qi Huang, Li Sun, Tengfei Bao, Zhe Dai

“…AIP represents a clinically convenient indicator for the detection of T2DM with high risk of complications and associated diseases and thus is a good predictor and indicator for follow-up monitoring in the treatment of patients with high-risk type 2 diabetes.…”
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Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models by Kathleen Bennett, Frank Moriarty, Tom Fahey, Caitriona Cahir

“…The largest reduction in QALYs and incremental cost was for benzodiazepines compared with no sedative medication (€3470, 95% CI €2434 to €5001; −0.07 QALYs, 95% CI −0.089 to –0.047), followed by NSAIDs relative to paracetamol (€806, 95% CI €415 and €1346; −0.07 QALYs, 95% CI −0.131 to –0.026), and maximal dose PPIs compared with maintenance dose PPIs (€989, 95% CI -€69 and €2127; −0.01 QALYs, 95% CI −0.029 to 0.003). …”
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Clinical characteristics of catatonic symptoms in children with autism spectrum disorder by LI Yongmei, HE Jieqiong, XING Yipei, LIU Xinghua, ZHU Huilin, DENG Hongzhu, ZOU Xiaobing

“…All six core motor symptoms were commonly reported in the positive group， with “requiring prompts to complete actions” being the most reported， followed by “immobility， getting stuck， slowness in movement， and problems stopping actions once started”. …”
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Dynamic assessment of long-term survival in survivors with stage III non-small cell lung cancer: a novel conditional survival model with a web-based calculator by Xiangdi Meng, Xiangdi Meng, Peihe Wang, Jie Liu, Daqing Sun, Zhuojun Ju, Yuanyuan Cai

“…It provided novel insights into clinical decisions in follow-up and treatment for survivors, offering a convenient tool for optimize resource allocation.…”
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Extensible lateral approach versus sinus tarsi approach for sanders type II and III calcaneal fractures osteosynthesis: a randomized controlled trial of 186 fractures by Amr A. Fadle, Ahmed A. Khalifa, Peter Mamdouh Shehata, Wael EL-Adly, Ahmed Ekram Osman

“…The radiological parameters were significantly better in STA postoperatively and at the last follow up. The AOFAS scores were significantly better in STA (83.49 ± 7.71 vs. 68.62 ± 7.05, respectively, p = 0.000). …”
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Association between adolescent obesity and early adulthood healthcare utilization—a two-cohort prospective study by Emilia Hagman, Vidar Halsteinli, Resthie R. Putri, Christina Hansen Edwards, Gudrun Waaler Bjørnelv, Claude Marcus, Rønnaug A. Ødegård

“…Individuals included were born between 1987 and 1994, with BMI measurements at ages 13–19, and follow-up data from ages 20 to 30 years. Healthcare utilization and costs were assessed using national patient registries. …”
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Opportunities for NCD screening and control efforts among people living with HIV/AIDS attending care and treatment clinic at a regional referral hospital in Dar es Salaam by Atuganile Musyani, Grace Mosi, Erik Kinyenje, Mucho Mizinduko, Rogath Kishimba, Meshack Shimwela, Leonard Subi

“…Methods The study employed a mixed-method approach, including a cross-sectional study to identify hypertension risk factors and pre–post-intervention follow-ups to assess NCD control rates among PLHIV. …”
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Associated Factors of Cholelithiasis among Younger Children with Sickle Cell Disease at the National Reference Center for Sickle Cell Disease in Brazzaville, Congo by Firmine Olivia Galiba Atipo Tsiba, Clément Pacha Mikia, Jennifer Armandine Elira Samba, Jade Vanessa Nziengui Mboumba, Félix Malanda, Clausina Mikolele Ahoui, Alexis Elira Dokekias

“…The 10–12 age group was the most represented (22 cases or 59.45%), followed by 7- to 9-year-olds (12 cases or 32.43%). …”
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Anticancer activity of mixed Graphene/Carbone nanotubes reinforced Sulfur-Containing polyketoamine nanocomposites by Khalid A. Khan, Gadeer R. Ashour, Mahmoud A. Hussein

“…The nanocomposites also showed pronounced anticancer effects, with PKA/GNS/MWCNTsa (IC50 = 92.89 μg/mL) being the most effective, followed by PKA/GNS/MWCNTsd (IC50 = 104.0 μg/mL), PKA/GNS/MWCNTsc (IC50 = 109.5 μg/mL), PKA/GNS/MWCNTsb (IC50 = 110.1 μg/mL), and pure PKA (IC50 = 149.4 μg/mL). …”
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In vitro and in silico Anti-diabetes mechanism of phytochemicals from Curculigo pilosa and its pharmacokinetic profiling via α-amylase inhibition by Damilola A. Omoboyowa, Temitope C. Aribigbola, Simbo T. Akinsulure, Damilola S. Bodun, Ezekiel A. Olugbogi, Ebenezer A. Oni

“…The ethylacetate, n-butanol and methanol extracts of C. pilosa were subjected to in vitro α-amylase inhibitory assay, followed by identification of the bioactive compounds from the most potent extract using HPLC. …”
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Prevalence and Determinants of Geohelminthiasis among School-Age Children in Jimma City, Ethiopia by Ahmed Zeynudin, Teshome Degefa, Sultan Suleman, Abdulhakim Abamecha, Zuber Hajikelil, Andreas Wieser

“…The prevalence of any STH among SAC was 23.4%, with Ascaris lumbricoides being the predominant STH species (15.7%), followed by Trichuris trichiura (9%) and hookworm (2.1%). …”
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Medication Belief and Adherence among Patients with Epilepsy by Yirga Legesse Niriayo, Abraham Mamo, Kidu Gidey, Gebre Teklemariam Demoz

“…The most common cause of nonadherence was forgetfulness (48.7%) followed by inability to get medicine (28.8) and safety concern (23.5%). …”
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Antifungal, Insecticidal, and Repellent Activities of Rosmarinus officinalis Essential Oil and Molecular Docking of Its Constituents against Acetylcholinesterase and β-Tubulin by Ghizlane Houzi, Youness El abdali, Ghada Beniaich, Mohamed Chebaibi, Mohamed Taibi, Amine Elbouzidi, Samiha Kaioua, Abdeslam Asehraou, Mohamed Addi, Khalid Chaabane, Rachid Flouchi, Aimad Allali, Soad Khal-Layoun

“…The analysis revealed a total of sixteen components in R. officinalis EO, with 1,8-cineole (40.80%) being the major constituent, followed by α-pinene (26.18%) and camphor (19.53%). …”
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Characterization of the Japanese Management Technique 5S. Polytechnic Dining Room Case by M. Izurieta, G. Miño, D. Vallejo

“…According to the results, those that obtained the highest rating of 7 were as follows: Seiris (classification) 25%, Seiton (Order) 36%, Seiso (Cleaning) 32%, Seiketsu (Standardization) 36%, and Shitsuke (Maintenance) 57%. …”
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Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center by Carl-Stephan Leonhardt, Leopold Lanzenberger, Raphael Puehringer, Ulla Klaiber, Irene Hauser, Oliver Strobel, Gerald Prager, Martin Bodingbauer

“…Methods This retrospective study followed the STROBE recommendations. All cases discussed at the MTB of the Landesklinikum Baden-Moedling, Austria, were eligible for inclusion. …”
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Prognostic Value of Endothelial Progenitor Cells in Acute Myocardial Infarction Patients by Gongjie Ye, Xiaodan Chen, Yinchao Zhou, Jianqing Zhou, Yongfei Song, Xiaoyong Yang, Lei Yang

“…Among these patients, 23 (25.3%) died from various causes during the follow-up period. The counts of EPCs were found to be significantly higher in the survival group compared to the death group (P<0.05). …”
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Safety, Efficacy, and Predictive Factors of Conventional Epithelium-Off Corneal Crosslinking in the Treatment of Progressive Keratoconus by Rebecca Farhat, Mohamad Khaled Ghannam, Georges Azar, Joseph Nehme, Marwan Sahyoun, Najib Georges Hanna, Mariana Abi Karam, Charbel El Haber, Alexandre Schakal, Alexandre Jalkh, Ameed Samaha

“…All patients with progressive keratoconus who underwent CXL between January 2008 and January 2016, with minimal 3-years follow-up were included. Primary treatment outcomes were maximum keratometry (K max), best-corrected distance visual acuity (CDVA), and failure. …”
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Neuroprotection against Amyloid-β-Induced DNA Double-Strand Breaks Is Mediated by Multiple Retinoic Acid-Dependent Pathways by Julien Colas, Natacha Chessel, Allaeddine Ouared, Emmanuelle Gruz-Gibelli, Pascale Marin, François R. Herrmann, Armand Savioz

“…Furthermore, it could be shown by a proximity ligation assay that the PPARβ/δ-RXR interactions, not the RARα/β/γ-RXR interactions, increased in the cells when a 10 min RA treatment was followed by a 20 min Aβ1-42 treatment. Thus, the PPARβ/δ receptor, known for its antiapoptotic function, might for these short-time treatments play a role in neuroprotection via PPARβ/δ-RXR heterodimerization and possibly expression of antiamyloidogenic genes. …”
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