Identification of candidate genes involved in Zika virus-induced reversible paralysis of mice by John D. Morrey, Venkatraman Siddharthan, Hong Wang, Alexandre L. R. Oliveira, Keiichiro Susuki, Rakesh Kaundal, Sara M. Freeman, Aaron J. Thomas, Naveen Duhan, Nathan G. Corry

“…Of these “biphasic” DEGs, 951 were up-regulated and 1107 were down-regulated during paralysis, followed by recovery. To refine the search for candidate DEGs we used gene ontology analysis and RT-qPCR to select 3 DEGs that could be involved with the node of Ranvier function and 5 DEGs that could be involved with synaptic function. …”
Get full text

Construction of Recombinant Inbred Lines and Indentification of QTL for Grain Number Traits of Gaozhou Wild Rice by Xing HUO, Yongmei YU, Shuqing QIU, Dilin LIU, Le KONG, Wuge LIU, Feng WANG

“…【Method】A recombinant inbred line population with wild rice ancestry was developed through crosses between Gaozhou wild rice and 'Zhonghua 11', followed by multiple generations of selfing. High-density genotyping arrays were used to genotype the population, and a high-density genetic map was constructed based on molecular marker analysis. …”
Get full text

Concomitant Usage of H1‐Antihistamines and Immune Checkpoint Inhibitors on Cancer Patient Survival by Yin Leung, Terry Cheuk‐Fung Yip, Grace Lai‐Hung Wong, Vincent Wai‐Sun Wong, Vicki Wing‐Ki Hui, Tony Shu‐Kam Mok, Henry Lik‐Yuen Chan, Stephen Lam Chan, Rashid Nok‐Shun Lui

“…A 1‐month landmark analysis was conducted with follow–for up to 6 months, including an exposure period of 1 month before and after the baseline date. …”
Get full text

An Effective and Safe Maize Seed Chipping Protocol Using Clipping Pliers With Applications in Small-Scale Genotyping and Marker-Assisted Breeding by Brian Zebosi, John Ssengo, Lander Geadelmann, Erica Unger-Wallace, Erik Vollbrecht

“…Small-scale marker-assisted selection laboratories rely heavily on leaf-based genotyping, which involves over-planting large, segregating populations followed by leaf sampling, genotyping, and backtracking to identify desired individuals, which is costly and laborious. …”
Get full text

Effects of coenzyme Q10 on endothelial and cardiac function in patients undergoing haemodialysis: study protocol for a pilot randomised controlled trial by Yongxing Xu, Enhong Han, Jianjun Gao, Xinlou Li, Xiaowen Zuo, Huaping Jia, Fugui Liang, Lei Xie

“…Eligible patients undergoing haemodialysis in our haemodialysis centre will be randomly allocated to the CoQ10 and control groups. The follow-up time is 12 months. The primary outcome is to assess the change of brachial artery endothelial-dependent flow-mediated dilation, left ventricular systolic function, diastolic function and Myocardial Performance Index at 12 months from baseline. …”
Get full text

Case report: an unusual long-term evolution of a diffuse midline glioma, H3K27 altered by Michael Griessmair, Michael Griessmair, Claire Delbridge, Claus Zimmer, Eva Mayr, Arthur Wagner, Julian Canisius, Marie-Christin Metz, Benedikt Wiestler, Benedikt Wiestler

“…The patient underwent biopsy, followed by microsurgical resection with molecular analysis. …”
Get full text

Joint exposure to multiple air pollutants and residual cardiovascular risk in hypertension by Yalan Li, Wei Hong, Jingjing Wu, Jie Wang, Shiqi Liu, Hong Yuan, Jingjing Cai, Rujia Miao, Jiangang Wang, Yao Lu

“…Results: Over an average follow-up period of 2.24 years (SD, 1.25), 706 hypertensive patients developed cardiovascular disease. …”
Get full text

Pedobarographic Measurements of Rheumatoid Feet Compared with Clinical Parameters by Yasemin YUMUSAKHUYLU, Bilinc DOGRUOZ KARATEKIN, Selin TURAN TURGUT, Afitap ICAGASIOGLU, Esra SELIMOGLU, Sadiye MURAT, Esen KASAPOGLU, Bekir TURGUT

“…Conclusions: Pedobarographic measurements can be considered as a follow-up evaluation tool for the evaluation of all foot parts (forefoot, midfoot, and hindfoot). …”
Get full text

Gut Dysbiosis and Abnormal Bile Acid Metabolism in Colitis-Associated Cancer by Li Liu, Min Yang, Wenxiao Dong, Tianyu Liu, Xueli Song, Yu Gu, Sinan Wang, Yi Liu, Zaripa Abla, Xiaoming Qiao, Wentian Liu, Kui Jiang, Bangmao Wang, Jie Zhang, Hailong Cao

“…The AOM/DSS group received AOM injection followed by DSS drinking water. Intestinal inflammation, mucosal barrier, and bile acid receptors were determined by real-time PCR and immunohistochemistry. …”
Get full text

Urea coated with cellulose acetate-lignin composite presents lower loss by ammonia volatilization by Jhonatan Nolasco Nascimento, Letícia Said Marangon, Fabiane Carvalho Ballotin, Renê Chagas da Silva, José Mauro de Almeida, Edison Márcio Mattiello, Reinaldo Bertola Cantarutti, Deusanilde de Jesus Silva

“…Ammonia volatilization was evaluated in a static capture system (24 h), with 2% boric acid, followed by titration with sulfuric acid (0.005 mol/L). …”
Get full text

Secondary neoplasms in survivors of pediatric acute lymphoblastic leukemia and lymphoblastic lymphoma: a single-center, retrospective study by Eri Ushida, Hidemi Toyoda, Atsushi Kohso, Yosuke Okumura, Kaori Niwa, Takahiro Ito, Mari Morimoto, Ryo Hanaki, Keishiro Amano, Shotaro Iwamoto, Takao Deguchi, Hiroki Hori, Masahiro Hirayama

“…The aim of this study was to evaluate the incidence of, risk factors for, and outcomes of secondary neoplasms in long-term survivors of ALL and LBL at a tertiary pediatric oncology center in Mie prefecture, Japan.ProcedureWe retrospectively reviewed 188 patients with ALL and LBL who were treated with an ALL-based therapeutic regimen at Mie University Hospital from January 1, 1977 to December 31, 2022 and followed up.ResultsTen patients developed secondary neoplasms, with 10-year and 20-year cumulative incidences of 2.9% [standard error (SE) = 1.5%] and 5.5% (SE = 2.3%), respectively. …”
Get full text

The International Vitreoretinal B-Cell Lymphoma Registry: a protocol paper by David J Wilson, Valérie Touitou, Justine R Smith, Manabu Mochizuki, Hiroshi Takase, Steven Yeh, Alexandra L Farrall, H Nida Sen, Daniel V Vasconcelos-Santos, Joke H de Boer, Ninette H ten Dam-van Loon, Janet L Davis, Anthony J Hall, Mark H B Radford

“…Customised software was designed to permit collection of these data across a single baseline and multiple follow-up forms. The platform collects data without identifiers and at 3 month reporting intervals. …”
Get full text

Psoriasis increases the risk of Sjögren’s syndrome: evidence from a propensity score-matched cohort study and transcriptomic analysis by Zijian Kang, Yu Du, Ran Cui, Qian Wang, Miao Chen, Yu-Hsun Wang, James Cheng‐Chung Wei, Sheng-Ming Dai

“…After propensity score matching, the baseline characteristics of both groups were balanced. During the follow-up period, 3339 patients with psoriasis and 1937 individuals without psoriasis developed SS. …”
Get full text

New insights into interspecies relationships, chromosomal evolution, and hybrid identification in the Lycoris Herb. by Yue Zhang, Shujun Zhou, Yu Chen, Pengchong Zhang, Yongchun Zhang, Junhuo Cai, Zixuan Nie, Lu Zhang

“…Results The findings indicate that species with a smaller basic chromosome number exhibit less asymmetry than those with a larger basic chromosome number, suggesting that species with different basic chromosome numbers may have followed different evolutionary pathways. Lycoris aurea has a more symmetrical karyotype, which may be the plesiomorphic state, reflecting an evolutionary transition from symmetry to asymmetry in Lycoris chromosomes. …”
Get full text

Dynamics of retinal changes in early-stage Parkinson’s disease by Ane Murueta-Goyena, Sara Teijeira-Portas, Elisa Blanco Martín, Raquel Vázquez-Picón, Blanca Ruiz Bajo, Jone Bocos, Jorge Sánchez-Molina, Patricia Alves Dias, Ioana Croitoru, Iñaki Rodríguez Agirretxe, Rocío Del Pino, Marian Acera, Beatriz Tijero, Oihane Sáez-Atxukarro, David Romero-Bascones, Juan Carlos Gómez-Esteban, Javier Aritz Urcola, Javier Ruiz Martínez, Iñigo Gabilondo

“…In PD patients, the baseline GCIPL thickness in central regions was increased by up to 4 μm, and the rate of thinning in the parafoveal GCIPL was − 0.61 [0.29] µm/year faster over a one-year follow-up period than in controls in the 2- to 3-mm ring (p = 0.039). …”
Get full text

Effect of empowerment-based interventions on self-efficacy and self-care capacity among patients with sickle cell disease: A randomized controlled trial by Zohour Ibrahim Rashwan, Hasan Abdali Khalil, Leena Mohamed Khonji, Gayathripriya Narayanan, Marwan Kamal Altheeb, Roseben Pradeep, Rajeswari Krishnasamy, Magda Mohamed Bayoumi

“…The intervention group received the empowerment-based intervention implemented through structured small-group discussion sessions, individualized consultations (5A model: assess, advise, agree, assist, and arrange), and follow-up sessions, while the control group received routine health education. …”
Get full text

Risk of depression in glaucoma patients with vision impairment: A nationwide cohort study by Sheng-Min Wang, Younhea Jung, Kyungdo Han, Kyoung Ohn, Hae-young Lopilly Park, Chan Kee Park, Jung Il Moon

“…Results: Among 3,680,570 individuals screened through the Korean National Health Screening Program in 2009, 681,515 were newly diagnosed with depression during follow-up. Subjects with glaucoma showed a higher risk of depression than those without glaucoma, with an adjusted hazard ratio (HR) of 2.011 (95 % confidence interval [CI]: 1.946–2.078) pre-adjustment and 1.085 (95 % CI: 1.050–1.121) post-adjustment for covariates. …”
Get full text

Impact of thyrotropin levels on outcomes in T1N0M0 papillary thyroid cancer after microwave ablation by Ying Wei, Zhen-Long Zhao, Jie Wu, Shi-Liang Cao, Na Yu, Li-Li Peng, Yan Li, Ming-An Yu

“…However, progression-free survival rates in M-PTC patients showed convergence across all TSH levels by the 5-year follow-up.Conclusion Maintaining TSH levels within the normal range post-ablation may be appropriate for managing T1N0M0 PTC treated with MWA, but randomized controlled trials are needed to confirm optimal TSH targets and their impact on outcomes.…”
Get full text

Use of Diced Cartilage for Management of Internal Mammary Vessel Exposure Sites in Autologous Breast Reconstruction by Ulf Dornseifer, MD, PhD, My L. Truong, Stephan Grumbrecht, MD, Peter P. Pfeiler, MD, Uli D. Haide, MD, DMD, Philipp Moog, MD, PhD, Michael Kimelman, MD

“…The effect of DC on breast contour was investigated using magnetic resonance imaging (>6 months postoperative) and photographic documentation (6-month follow-up). Results:. DC was used in 114 of 173 included reconstructions (DC, n = 55; DCR, n = 59; control, n = 59). …”
Get full text

In vitro effect of hCG on cryptorchid patients’ gubernacular cells: a predictive model for adjuvant personalized therapy by Andrea Errico, Giulia Ambrosini, Sara Vinco, Emanuela Bottani, Elisa Dalla Pozza, Nunzio Marroncelli, Jessica Brandi, Daniela Cecconi, Ilaria Decimo, Filippo Migliorini, Nicola Zampieri, Ilaria Dando

“…The most effective method to treat cryptorchidism is orchiopexy, followed by human chorionic gonadotropin (hCG) therapy; however, a portion of treated patients do not show a significant improvement in testis volume and vascularization after adjuvant therapy. …”
Get full text