Severe Late-Onset Drug-Induced Immune Thrombocytopenia Following IFN β-1a Treatment: A Case Report of a 52-Year-Old Woman with Relapse-Remitting Multiple Sclerosis by Christophe Cisarovsky, Marie Théaudin, Pierre-Alexandre Bart, Grégoire Stalder, Lorenzo Alberio

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Orthodontic Treatment and Maxillary Anterior Segmental Distraction Osteogenesis of a Subject with Williams–Beuren Syndrome and Isolated Cleft Palate: A Long-Term Follow-Up from the Age of 5 to 24 Years by Tetsutaro Yamaguchi, Tatsuo Shirota, Mohamed Adel, Masahiro Takahashi, Shugo Haga, Ryo Nagahama, Misato Nakashima, Mayu Furuhata, Takaaki Kamatani, Koutaro Maki

“…In this case report, we present the combined orthodontic and surgical treatment of a WBS patient with an isolated cleft palate through a long-term follow-up from the age of 5 to 24 years. During the period of active treatment, comprehensive orthodontic treatment combined with maxillary anterior segmental distraction osteogenesis and prosthetic treatment using dental implants were effective in dramatically improving the patient’s malocclusion. …”
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New Dimensional Staging of Bisphosphonate-Related Osteonecrosis of the Jaw Allowing a Guided Surgical Treatment Protocol: Long-Term Follow-Up of 266 Lesions in Neoplastic and Osteoporotic Patients from the University of Bari by Simonetta Franco, Simona Miccoli, Luisa Limongelli, Angela Tempesta, Giorgio Favia, Eugenio Maiorano, Gianfranco Favia

“…The surgical procedure was complemented by piezosurgery and followed by the application of hyaluronate and amino acids. …”
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Clinical Outcomes of Aberration-Free All Surface Laser Ablation (ASLA) vs. Aberration-Free ASLA Assisted by Smart Pulse Technology in High Myopia: A One-Year Follow-Up Study by XiaoHao Du, Jia Zhang, Meng Su, WenJia Cao, Shuang Zeng, QinMei Wang, Ioannis M. Aslanides, ShiHao Chen

“…Examinations such as visual acuity, refraction, and haze were performed before the 12-month follow-up. Corneal epithelial healing time was assessed in the first postoperative day. …”
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Clinical and radiographic assessment of the efficacy of platform switched implant and papilla preservation flap design in minimizing crestal bone loss around single tooth implant: A 6-month follow-up Study by Tejaswani Kaur, Dilip Naik, Ashita Uppoor, Sangeeta Umesh Nayak, Pragya Atray

“…Conclusion: Results show that minimum crestal bone loss was seen in Group C, followed by Group B, and maximum bone loss was seen in Group A. …”
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Poor Control of Plasma Triglycerides Is Associated with Early Decline of Estimated Glomerular Filtration Rates in New-Onset Type 2 Diabetes in China: Results from a 3-Year Follow-Up Study by Chuan Wang, Lingshu Wang, Kai Liang, Fei Yan, Xinguo Hou, Fuqiang Liu, Li Chen

“…We conducted a 3-year follow-up study, involving 283 subjects with new-onset T2DM, and observed the effect of baseline and follow-up metabolic abnormalities, especially dyslipidemia, on the early damage of kidney function using multiple logistic regression analysis. …”
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Strategies adopted by men to deal with uncertainty and anxiety when following an active surveillance/monitoring protocol for localised prostate cancer and implications for care: a longitudinal qualitative study embedded within the ProtecT trial by Chris Metcalfe, Jenny Donovan, Julia Wade, Vincent J Gnanapragasam, Michael Davis, David Neal, Richard Martin, Athene Lane, Edward Rowe, Freddie Hamdy, James Catto, Emma Turner, David Gillatt, Eleanor Walsh, Derek Rosario, Tim Peters, Roger Kockelbergh, Alan Paul, Peter Holding, Howard Kynaston, Owen Hughes, Prasad Bollina, Alan Doherty, Edgar Paez

“…This study investigated men’s strategies for coping with the uncertainties of active monitoring (AM, a surveillance strategy within the Prostate testing for cancer and Treatment, ProtecT trial) over the longer term and implications for optimising supportive care.Design Longitudinal serial in-depth qualitative interviews every 2–3 years for a median 7 (range 6–14) years following diagnosis.Setting Four centres within the UK Protect trial.Participants Purposive sample of 20 men with localised PCa: median age at diagnosis 64 years (range 52–68); 15 (75%) had low-risk PCa; 12 randomly allocated to, 8 choosing AM. …”
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Malapposed Struts with Cre8, Biomatrix, and Xience Stents Assessed with OCT Immediately after Implantation and at 6-Month Follow-Up: Can the Different Biomechanical Characteristics of the Three Stents Impact on Struts Malapposition? by Cristina Giglioli, Emanuele Cecchi, Chiara Formentini, Marco Chiostri, Niccolò Marchionni, Salvatore Mario Romano

“…In this study, which is a subanalysis of the previously published CREBX-OCT study, we compared optical coherence tomography (OCT) analysis at the index percutaneous coronary intervention (PCI) and at six-month follow-up in 37 patients randomly assigned to receive, by a single operator, three different second-generation drug-eluting stents (Cre8, Biomatrix, and Xience) aiming to clarify if the malapposition observed at six-month follow-up was persistent or late-acquired. …”
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Can Orthodontic Treatment Be Stable 20 Years after the End of the Treatment Scheme? Treatment of a Class 2, Division 1 Malocclusion with Severe Skeletal Discrepancy and Its 20-Year Follow-Up by Domenico Aiello, Riccardo Nucera, Stefania Costa, Michele Mario Figliuzzi, Sergio Paduano

“…The first treatment phase involved the use of a Bass type for 12 months at the end of the functional treatment; the second phase of fixed therapy was carried out following the principles of bioprogressive techniques. …”
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Management of peritoneal dialysis patients under the regular prevention and control of COVID-19 (新型冠状病毒肺炎疫情防控常态化下腹膜透析患者的管理) by ZHAO Xin (赵欣), LIU Yuting (刘宇婷), LI Hongxian (李红仙)

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Nursing management in the fecal microbiota transplantation for a child with autism (1例孤独症患儿行粪菌移植术的护理) by WANG Suling (王苏玲), ZHU Huiyun (朱慧云), LI Changyan (李畅妍), LUO Ying (罗颖)

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HIV self-testing positivity rate and linkage to confirmatory testing and care: a telephone survey in Côte d’Ivoire, Mali, and Senegal by Kra, Arsène Kouassi, Fotso, Arlette Simo, Rouveau, Nicolas, Maheu-Giroux, Mathieu, Boily, Marie-Claude, Silhol, Romain, d’Elbée, Marc, Vautier, Anthony, Larmarange, Joseph

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Follow-Up Study on Acoustic De-Licing of Atlantic Salmon (<i>Salmo salar</i>): <i>Lepeophtheirus salmonis</i> and <i>Caligus elongatus</i> Dynamics over Four Consecutive Production Cycles by Albert Kjartan Dagbjartarson Imsland, Pablo Balseiro, Sigurd Handeland, Olav Rune Godø

“…We monitored four production cycles, with AcuLice applied for two of the production cycles and with no AcuLice treatment applied during the other two production cycles as control. This is a follow-up study to our previous work. The numbers of salmon lice treatments and of weeks until the first salmon lice treatment were also compared in the two experimental groups. …”
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Healing potentiality of blood clot, S-PRF and A-PRF as scaffold in treatment of non-vital mature single rooted teeth with chronic peri-apical periodontitis following regenerative endodontic therapy: randomized clinical trial by Omnia Badawy Darwish, Said Mohamed Abdel Aziz, Hany Samy Sadek

“…A standardized radiograph was taken, and the patients instructed for 6, 12 and 18 months follow up periods. Fisher's exact test was applied to compare the frequency of PAI scores at different follow-up intervals between the three groups. …”
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Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma &le;3 cm in Potentially Transplantable Patients: A Over 10-Year Survival Study by Chen S, Qi H, Tan H, Cao F, Xie L, Huang T, Wu Y, Wen C, Wang Y, Shen L, Fan W

“…Shuanggang Chen,1,2,&ast; Han Qi,1,2,&ast; Hongtong Tan,1,2,&ast; Fei Cao,1,2 Lin Xie,1,2 Tao Huang,1,2 Ying Wu,3 Chunyong Wen,1,2 Yujia Wang,1,2 Lujun Shen,1,2 Weijun Fan1,2 1Department of Minimally Invasive Interventional Therapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 2State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 3Department of Interventional Therapy, Shenzhen second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Weijun Fan, Email fanwj@sysucc.org.cn; Lujun Shen, Email shenlj@sysucc.org.cnBackground: Salvage liver transplantation is promising for hepatocellular carcinoma(HCC) recurrence post-ablation but is significantly affected by recurrence beyond Milan Criteria (RBM).Materials and Methods: A retrospective cohort study of potentially transplantable HCC patients undergoing ablation between 2007 and 2017 assessed median time to recurrence beyond Milan Criteria(TRBM) via Kaplan-Meier curves and predictive capacity of recurrence and RBM for overall survival(OS) via Receiver Operating Characteristic Curves, and identified independent risk factors for TRBM and RBM via Cox and binary logistic regression models.Results: We enrolled 191 potentially transplantable patients with early-stage HBV-related HCC ≤ 3 cm who underwent ablation. During a median follow-up of 7.64 years, HCC recurrence occurred in 126 patients(65.9%), with RBM 86 patients(45.0%). …”
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Hormone replacement therapy, menopausal age and lifestyle variables are associated with better cognitive performance at follow-up but not cognition over time in older-adult women irrespective of APOE4 carrier status and co-morbidities by Tamlyn J. Watermeyer, Tamlyn J. Watermeyer, Sarah Gregory, Sarah Gregory, Emmi Leetham, Chinedu T. Udeh-Momoh, Chinedu T. Udeh-Momoh, Chinedu T. Udeh-Momoh, Chinedu T. Udeh-Momoh, Chinedu T. Udeh-Momoh, Graciela Muniz-Terrera, Graciela Muniz-Terrera

“…The study underscores the need for longer follow-up periods, consideration of other female-specific risk factors, and more comprehensive lifestyle and health assessments to clarify the complex interplay between HRT use, reproductive history, lifestyle, comorbidities and cognitive aging in women.…”
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Death incidents following transcatheter edge-to-edge repair (TEER) with the MitraClip device: analysis of 10-years post-marketing death reports from the Manufacturer and User Facility Device Experience (MAUDE) registry by Xinghe Sun, Yifei Zhao, Yan Li

“…Results During the 10-year period following FDA approval, the MAUDE database recorded a total of 927 death reports and 9,211 injury reports associated with MitraClip. …”
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Study protocol for an epidemiological study ‘Multimorbidity − identifying the most burdensome patterns, risk factors and potentials to reduce future burden (MOLTO)’ based on the Finnish health examination surveys and the ongoing register-based follow-up by Annamari Lundqvist, Seppo Koskinen, Päivikki Koponen, Tuija Jääskeläinen, Jaana Suvisaari, Jutta Järvelin

“…The burden caused by multimorbidity as well as risk and protective factors for multimorbidity will be analysed by survival analysis methods such as Cox proportional hazards and Poisson regression models.Ethics and dissemination The survey data have been collected following the legislation at the time of the survey. …”
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Can the Onset of Type 2 Diabetes Be Delayed by a Group-Based Lifestyle Intervention in Women with Prediabetes following Gestational Diabetes Mellitus (GDM)? Findings from a Randomized Control Mixed Methods Trial by Angela O’Dea, Marie Tierney, Brian E. McGuire, John Newell, Liam G. Glynn, Irene Gibson, Eoin Noctor, Andrii Danyliv, Susan B. Connolly, Fidelma P. Dunne

“…The primary outcome variable was the change in fasting plasma glucose (FPG) from study entry to one-year follow-up. Results. At one-year follow-up, the intervention group showed significant improvements over the wait control group on stress, diet self-efficacy, and quality of life. …”
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Medication Adherence Mediates the Association between Type D Personality and High HbA1c Level in Chinese Patients with Type 2 Diabetes Mellitus: A Six-Month Follow-Up Study by Xuemei Li, Min Gao, Shengfa Zhang, Huiwen Xu, Huixuan Zhou, Xiaohua Wang, Zhiyong Qu, Jing Guo, Weijun Zhang, Donghua Tian

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