Bias Mitigation in Primary Health Care Artificial Intelligence Models: Scoping Review by Maxime Sasseville, Steven Ouellet, Caroline Rhéaume, Malek Sahlia, Vincent Couture, Philippe Després, Jean-Sébastien Paquette, David Darmon, Frédéric Bergeron, Marie-Pierre Gagnon

“…Other methods aimed at enhancing model fairness included group recalibration and the application of the equalized odds metric. However, these approaches sometimes exacerbated prediction errors across groups or led to overall model miscalibrations. …”
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A Nomogram Based on Circulating Inflammatory Factors for Predicting Prognosis of Newly Diagnosed Multiple Myeloma Patients by Wang M, Yue X, Ding Y, Cai Z, Xiao H, Huang H, He J

“…Mowang Wang,1– 4,* Xiaoyan Yue,5,* Yingying Ding,5,* Zhen Cai,1,4 Haowen Xiao,5 He Huang,1– 4 Jingsong He1,4 1Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of China; 2Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, Zhejiang Province, People’s Republic of China; 3Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of China; 4Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang Province, People’s Republic of China; 5Department of Hematology and Cell Therapy, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: He Huang; Jingsong He, Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, Zhejiang Province, 310006, People’s Republic of China, Email huanghe@zju.edu.cn; hejingsong@zju.edu.cnPurpose: The growth and survival of multiple myeloma (MM) cells depend heavily on bone marrow microenvironment, where inflammation emerges as a significant feature and is commonly associated with unfavorable prognosis in MM. …”
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Intranasal Administration of the Combination of Dextro-Ketamine and Dexmedetomidine for Treatment of Diabetic Neuropathic Pain in Rats by Sudo SZ, Montagnoli TL, Dematté BE, Santos AD, Trachez MM, Gubert F, Mendez-Otero R, Zapata-Sudo G

“…Susumu Zapata Sudo,1,* Tadeu Lima Montagnoli,2,* Bruno Eduardo Dematté,3 Aimeé Diogenes Santos,2 Margarete Manhães Trachez,4 Fernanda Gubert,5 Rosalia Mendez-Otero,6 Gisele Zapata-Sudo1– 5 1Programa de Pós-Graduação em Medicina (Cirurgia Geral), Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; 2Programa de Pós-Graduação em Farmacologia e Química Medicinal, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; 3Programa de Pós-Graduação em Medicina (Cardiologia), Instituto do Coração Edson Saad, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; 4Instituto do Coração Edson Saad, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; 5Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; 6Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil*These authors contributed equally to this workCorrespondence: Gisele Zapata-Sudo, Instituto do Coração Edson Saad, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil, Email gsudo@icb.ufrj.br; gzsudo@gmail.comIntroduction: Diabetes mellitus (DM) has become a public health problem, which is associated with high morbidity and mortality, due to the chronic complications, such as diabetic neuropathy. …”
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Anatomy, histology, and morphology of fish gills in relation to feeding habits: a comparative review of marine and freshwater species by Mohamed A. M. Alsafy, Hanan H. Abd-Elhafeez, Ahmed M. Rashwan, Atef Erasha, Safwat Ali, Samir A. A. El-Gendy

“…The gill rakers in lateral rows are longer, equal, or more in number and more developed than those of the medial rows, except at three gill arches in striped-red mullet fish, the second and third gill arches in pufferfish, and the fourth arch in Pagrus pagrus. gill rakers are absent at the first and second gill arches in Bagrus bayad. …”
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Causes and determinants of infant mortality using verbal autopsy and social autopsy methods in a rural population of Odisha: a community-based matched case-control study by Amit Kumar Satapathy, Arvind Kumar Singh, Priyamadhaba Behera, Debkumar Pal, Abhisek Mishra

“…The cause of infant deaths should be assessed in both medical and social contexts.Objectives We aimed to determine the medical causes of infant mortality by verbal autopsy and its determinants in two rural blocks of the Khordha district of Odisha and assess the pathway of care and delay in seeking care for the illness preceding infant death using the three-delay model.Design We conducted this community-based matched case-control study to identify the medical causes of infant mortality using the verbal autopsy method along with the identification of delay and pathway of care related to infant deaths using a social autopsy method.Settings Two rural blocks of Odisha, India.Participants We enumerated 100 infant deaths by active surveillance and data triangulation from Accredited Social Health Activists, Auxiliary Nurse Midwives and block-level health information systems. We selected an equal number of alive infants matched with cases in a 1:1 ratio with regard to age, gender and residential address.Outcome measures We conducted the verbal autopsy using the Sample Registration System verbal autopsy tool, where the cause of death ascertainment was done by two independently trained physicians followed by adjudication by one senior trained physician in case of conflicts. …”
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Exosomes Derived from Apelin-Pretreated Mesenchymal Stem Cells Ameliorate Sepsis-Induced Myocardial Dysfunction by Alleviating Cardiomyocyte Pyroptosis via Delivery of miR-34a-5p by Li T, Zhao Y, Cao Z, Shen Y, Chen J, Huang X, Shao Z, Zeng Y, Chen Q, Yan X, Li X, Zhang Y, Hu B

“…Ting Li,1,2,* Yuechu Zhao,3,* Zhi Cao,2,* Ying Shen,2 Jiaqi Chen,2 Xinran Huang,2 Zhuang Shao,2 Yi Zeng,2 Qi Chen,2 Xiaofei Yan,3 Xin Li,1,2 Yuelin Zhang,1,2 Bei Hu1,2 1School of Medicine, South China University of Technology, Guangzhou, Guangdong, People’s Republic of China; 2Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 3Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuelin Zhang; Bei Hu, Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, 510080, People’s Republic of China, Tel +86-20-83827812-20974, Email zhangyuelin1999@163.com; qhubei@hotmail.comBackground: Exosomes sourced from mesenchymal stem cells (MSC-EXOs) have become a promising therapeutic tool for sepsis-induced myocardial dysfunction (SMD). …”
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Prediction of Distant Metastasis of Renal Cell Carcinoma Based on Interpretable Machine Learning: A Multicenter Retrospective Study by Dong J, Duan M, Liu X, Li H, Zhang Y, Zhang T, Fu C, Yu J, Hu W, Peng S

“…Jinkai Dong,1,* Minjie Duan,2,3,* Xiaozhu Liu,4,* Huan Li,5 Yang Zhang,6 Tingting Zhang,7 Chengwei Fu,1 Jie Yu,8 Weike Hu,9 Shengxian Peng9,* 1Senior Department of Urology, the Third Medical Center of PLA General Hospital, Beijing, People’s Republic of China; 2Medical School of Chinese PLA, Beijing, People’s Republic of China; 3Medical Innovation Research Department, Chinese PLA General Hospital, Beijing, People’s Republic of China; 4Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 5Chongqing College of Electronic Engineering, Chongqing, People’s Republic of China; 6College of Medical Informatics, Chongqing Medical University, Chongqing, People’s Republic of China; 7Department of Endocrinology, Fifth Medical Center of Chinese PLA Hospital, Beijing, People’s Republic of China; 8Department of Medical Imaging, The Affiliated Taian City Central Hospital of Qingdao University, Taian, People’s Republic of China; 9Scientific Research Department, First People’s Hospital of Zigong City, Zigong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shengxian Peng, Scientific Research Department, First People’s Hospital of Zigong City, No. 42, 1st Street, Shangyihao, ZiLiuJing District, ZiGong, SiChuan, 643000, People’s Republic of China, Email 13258280319@163.comBackground: : The traditional tool for predicting distant metastasis in renal cell carcinoma (RCC) is still insufficient. …”
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Remimazolam Suppresses Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury by Regulating AKT/GSK-3β/NRF2 Pathway by Duan M, Yu N, Liu J, Zhao Y, Zhang J, Song S, Wang S

“…Mei Duan,1,* Ning Yu,1,* Jia Liu,1 Yang Zhao,1 Jing Zhang,1 Siyi Song,2 Shilei Wang1 1Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China; 2Department of Anesthesia and Perioperative Medicine, The First Affiliated Hospital of Shandong First Medical University, Jinan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shilei Wang, Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China, Tel +86 186 6180 6773, Email wshlei@aliyun.comIntroduction: The mechanism of remimazolam, a benzodiazepine that activates γ-aminobutyric acid a (GABAa) receptors, in cerebral ischemia/reperfusion (I/R) injury is not well understood. …”
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IL-8 Downregulation Mediates the Beneficial Effects of Infection-Induced Fever on Breast Cancer Prognosis by Li H, Liang X, Ma J, Liu Q, Lin Y, Tang J, Ren Z, Liang Z

“…Heliang Li,1,2,* Xinyan Liang,1,2,* Jiafan Ma,1,2,* Qiang Liu,1,2 Ying Lin,3 Junpeng Tang,4 Zefang Ren,5 Zhuozhi Liang1,2,6 1Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 2Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 3Breast Disease Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China; 4Department of Emergency Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China; 5The School of Public Health, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 6Zenith Institute of Medical Sciences, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhuozhi Liang; Zefang Ren, Email liangzhzh6@mail2.sysu.edu.cn; renzef@mail.sysu.edu.cnPurpose: Previous studies have reported that infection-induced fever is associated with improved breast cancer prognosis, potentially through the modulation of cytokines. …”
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Silk Protein Gene Engineering and Its Applications: Recent Advances in Biomedicine Driven by Molecular Biotechnology by Ji X, Li Y, Wang J, Wang G, Ma B, Shi J, Cui C, Wang R

“…Xingxiang Ji,1,* Yanyan Li,2,* Jingsheng Wang,3,* Gang Wang,3,* Bin Ma,4 Jingfei Shi,5 Chao Cui,6,7 Ruiming Wang1 1State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan, Shandong, 250353, People’s Republic of China; 2Key Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, 250014, People’s Republic of China; 3Department of Cardiovascular Medicine, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong, 271000, People’s Republic of China; 4Department of Cardiovascular Medicine, Taian City Taishan District People’s Hospital, Taian, Shandong, 271000, People’s Republic of China; 5Department of Clinical and Basic Medicine, Shandong First Medical University, Jinan, Shandong, 250000, People’s Republic of China; 6Scientific Research Department, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China; 7Department of Pharmacy, The Affiliated Taian City Central Hospital of Qingdao University, Taian, Shandong, 271000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chao Cui, Scientific Research Department, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China, Email hbkjcuichao@126.com Ruiming Wang, State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan, Shandong, 250353, People’s Republic of China, Email ruiming3k@163.comAbstract: Silk protein, as a natural polymer material with unique structures and properties, exhibits tremendous potential in the biomedical field. …”
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Traditional and Non-Traditional Risk Factors of Acute Coronary Syndrome in Young Women: Evidence from the ANCORS-YW Study by Ibdah R, Al-Nusair M, Abuhalimeh R, Mahmoud SA, Laswi B, Rawashdeh S, Hamoudeh A, Kheirallah KA

“…Rasheed Ibdah,1,* Mohammed Al-Nusair,1,* Raghad Abuhalimeh,2 Saad A Mahmoud,1 Bushra Laswi,1 Sukaina Rawashdeh,1 Ayman Hamoudeh,3 Khalid A Kheirallah4 1Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 2School of Medicine, University of Jordan, Amman, Jordan; 3Department of Cardiology, Istishari Hospital, Amman, Jordan; 4Department of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan*These authors contributed equally to this workCorrespondence: Khalid A Kheirallah, Jordan University of Science and Technology, P. …”
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High BMP7 Expression May Worsen Airway Disease in COPD by Altering Epithelial Cell Behavior by Dong W, Xie M, Ming C, Li H, Xu X, Cui L, Wang W, Li Y

“…Wenyan Dong,1,* Mengshuang Xie,2,* Chunjie Ming,3 Haijun Li,2 Xia Xu,2 Liwei Cui,4 Wei Wang,5 Yi Li6 1Department of General Practice, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 2Department of Geriatric Medicine, Laboratory of Gerontology and Anti-aging Research, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 3National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 4Department of Pulmonary and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 5Medical Integration and Practice Center, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 6Department of Obstetrics and Gynecology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Wang; Yi Li, Email styw28@163.com; 202062009073@email.sdu.edu.cnPurpose: Airway disease is the main pathological basis of chronic obstructive pulmonary disease (COPD), but the underlying mechanisms are unknown. …”
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A Multifunctional MIL-101-NH2(Fe) Nanoplatform for Synergistic Melanoma Therapy by Shang J, Chen Y, Wang F, Yang J, Li Y, Yang L, Liu X, Zhong Z, Yue C, Zhou M

“…Jinlu Shang,1,2,* Yongjun Chen,2,* Fangliang Wang,3,* Jing Yang,2 Yi Li,4 Liuxuan Yang,2 Xiuqiong Liu,1 Zhirong Zhong,5 Chaochi Yue,6 Meiling Zhou2 1Department of Pharmacy, West China Hospital Sichuan University Jintang Hospital, Chengdu, Sichuan, 610400, People’s Republic of China; 2Department of Pharmacy, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 3Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing Pharmacodynamic Evaluation Engineering Technology Research Center, College of Pharmacy Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4Department of Nuclear Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 5Department of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Meiling Zhou; Chaochi Yue, Email meilzhou@163.com; yuechaochi18@swmu.edu.cnBackground: Melanoma is an aggressive form of skin cancer, and single-modality treatments often fail to prevent tumor recurrence and metastasis. …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…Huiqin Zhou,1– 3,* Yunjia Peng,2,3,* Xinhua Huo,2,3 Bingqing Li,2,3 Huasheng Liu,4 Jian Wang,3,5 Gaihua Zhang1 1College of Life Sciences, Hunan Normal University, Changsha, People’s Republic of China; 2Hunan Guangxiu Hospital, Hunan Normal University, Changsha, People’s Republic of China; 3National Engineering Center of Human Stem Cell, Changsha, People’s Republic of China; 4Department of Radiology, The Third Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 5The Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Sciences, Central South University, Changsha, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gaihua Zhang, The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, China. …”
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Capital structure, profitability, and short-term solvency of nascent SMEs in Ghana: An empirical study by Karikari Amoa-Gyarteng, Shepherd Dhliwayo

“…Second, by showing that the trade-off theory’s tenets are relevant to the short-term solvency of nascent SMEs, the study demonstrates that capital structure theories apply equally to SMEs, just as much as large firms…”
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Non-Luminal Disease Score for Everolimus in Patients with Hormone Receptor‑positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Mult... by Tan Y, Jiang H, Tian X, Ma F, Wang J, Zhang P, Xu B, Fan Y, Zhao W

“…Yujing Tan,1,* Hanfang Jiang,2,* Xinzhu Tian,1,* Fei Ma,1 Jiayu Wang,1 Pin Zhang,1 Binghe Xu,1 Ying Fan,1 Weihong Zhao3 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, People’s Republic of China; 2Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing, 100142, People’s Republic of China; 3Department of Medical Oncology, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Fan; Weihong Zhao, Email fanying@cicams.ac.cn; zhaowh0818@163.comPurpose: This study aims to explore the role of the non-luminal disease score (NOLUS) for everolimus in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC).Methods: NOLUS has previously been established as an algorithm: NOLUS (0– 100) = − 0.45 × ER(%) − 0.28 × PR(%) + 0.27 × Ki67(%) + 73. …”
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The Diagnostic Value of Plasma NETs Levels and iCEB in Silent Myocardial Ischemia in Maintenance Hemodialysis Patients by Liu H, Han J, Ni W, Lu Y, Hu X, Wang J, Zhou Y, Wang Z, Cao J, Liu H

“…Haifei Liu,1,2,* Junling Han,3,* Weijie Ni,2 Yuan Lu,2 Xinhui Hu,2 Jing Wang,2 Yan Zhou,2 Ze Wang,4 Jingyuan Cao,1 Hong Liu2 1Department of Nephrology, The Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, 225300, People’s Republic of China; 2Institute of Nephrology, Zhongda Hospital, Southeast University School of Medicine, Nanjing, Jiangsu, 210009, People’s Republic of China; 3Clinical Laboratory, The Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, 225300, People’s Republic of China; 4Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Liu; Jingyuan Cao, Email jstzliu@sina.com; caojingyuan1989@163.comObjective: This study evaluated the diagnostic value of plasma Neutrophil extracellular traps (NETs) levels and the index of cardiac electrophysiological balance (iCEB) in identifying silent myocardial ischemia (SMI) in maintenance hemodialysis (MHD) patients.Methods: This cross-sectional observational study involved patients receiving MHD treatment. …”
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Effect of Esketamine on Cognitive Recovery After Propofol Sedation for Outpatient Colonoscopy: A Randomized Clinical Trial by Liu D, Gao X, Zhuo Y, Cheng W, Yang Y, Wu X, Yang H, Yao Y

“…Deshan Liu,1,* Xiuchai Gao,2,* Yifen Zhuo,3,* Wanjie Cheng,4 Ying Yang,4 Xiaoyan Wu,4 Huobao Yang,5 Yusheng Yao4,5 1Department of Neurology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, People’s Republic of China; 2Department of Anesthesiology, Fujian Xiapu County Hospital, Xiapu, Fujian, People’s Republic of China; 3Department of Anesthesiology, Xiamen Haicang Hospital, Xiamen, Fujian, People’s Republic of China; 4Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, People’s Republic of China; 5Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou, Fujian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Huobao Yang; Yusheng Yao, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, 134 Dongjie Street, Fuzhou, Fujian, 350001, People’s Republic of China, Email paulyang003@fjmu.edu.cn; fjslyys@126.comPurpose: While esketamine shows promise as an adjunct in procedural sedation, its impact on postoperative cognitive recovery remains incompletely characterized. …”
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The Clinical Value of the Combined Detection of Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Prognostic Nutritional Index (PNI) in Ear... by Zheng J, Zheng L, Wang X, Mao X, Wang Q, Yang Y, Mo D

“…Junyu Zheng,1,* Lijun Zheng,2,* Xiao Wang,3 Xuelian Mao,1 Qin Wang,1 Yining Yang,1 Dongping Mo1 1Department of Clinical Laboratory, Jiangsu Cancer Hospital & Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, People’s Republic of China; 2Department of Clinical Laboratory, Nanjing Lishui District Hospital of Traditional Chinese Medicine, Nanjing, People’s Republic of China; 3Department of CT, Jiangsu Cancer Hospital & Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dongping Mo, Department of Clinical Laboratory, Jiangsu Cancer Hospital & Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Institute of Cancer Research, Baizi Ting No. 42, Nanjing, Jiangsu, 210009, People’s Republic of China, Email moxiaoyubang@163.comObjective: Gastric cancer (GC) is a common malignant tumor of the digestive tract. …”
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Co-Delivery of Dacarbazine and miRNA 34a Combinations to Synergistically Improve Malignant Melanoma Treatments by Ding B, Li M, Zhang J, Zhang X, Gao H, Gao J, Shen C, Zhou Y, Li F, Liu A

“…Baoyue Ding,1,2,* Mingjuan Li,2,* Jie Zhang,2,* Xiaojuan Zhang,2 Huan Gao,2 Jianqing Gao,3 Chunyan Shen,4 Yan Zhou,4 Fanzhu Li,5 Ailin Liu1 1Department of Pharmaceutical Analysis, Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, The School of Pharmacy, Fujian Medical University, Fuzhou, 350122, People’s Republic of China; 2Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, Jiaxing University College of Medicine, Jiaxing, Zhejiang, People’s Republic of China; 3Institute of Pharmaceutics, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058 People’s Republic of China; 4Jiaxing Institute for Food, Drug and Product Quality Control, Jiaxing, Zhejiang, People’s Republic of China; 5Zhejiang Chinese Medical University, School of Pharmaceutical Science, Hangzhou, 310053, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fanzhu Li; Ailin Liu, Email lifanzhu@zcmu.edu.cn; ailinliu@mail.fjmu.edu.cnPurpose: The incidence of malignant melanoma (MM) has risen over the past three decades, and despite advancements in treatment, there is still a need to improve treatment modalities. …”
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