Efficacy of total transanal laparoscopic pull‑through and pure transanal endorectal pull‑through in the treatment of common‑type Hirschsprung disease by Guizhen Huang, Wenqian Huang, Chi Sun, Meng Li, Chaosheng He, Yi Su, Weili Xu, Suolin Li

“…The patients were divided into 2 equal-size groups according to the treatment method. …”
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Factors associated with caffeine intake among undergraduates: a cross-sectional study from Palestine by May Hamdan, Souzan Zidan, Fatima Al-Amouri, Hiba Niroukh, Manar Abu Dawod, Sajeda Ashour, Shahd Sameer Dweik, Manal Badrasawi

“…The sample was distributed almost equally between the first (26.3%), second (23.0%), third (22.8%), and fourth (18.7%) academic years, and only 44 undergraduates (9.1%) were in their fifth year. …”
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Efficacy of Transcutaneous Electrical Acupoint Stimulation on Modulating Upper Extremity Sympathetic Skin Response in Alleviating Cancer Survivors With Chemotherapy-Induced Periphe... by Xu Y, Wu J, Jiang Q, Lv Y, Zhou J, Wang Z, Zhao H, Du D

“…Yongming Xu,1,* Junzhen Wu,1,* Qingqing Jiang,2 Yingying Lv,1 Jin Zhou,1 Zhiyu Wang,3 Hui Zhao,3 Dongping Du1 1Department of Pain Management Center, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Neurology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Department of Internal Oncology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dongping Du, Department of Pain Management Center, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China, Tel +86-21-24058896, Email dudp@sjtu.edu.cn Hui Zhao, Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, 600 Yishan Road, Shanghai, 200233, People’s Republic of China, Tel +86-21-24058328, Fax +86-21-240598328, Email zhao-hui@sjtu.edu.cnObjective:  Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy and it is currently intractable We compared the efficacy of transcutaneous electrical acupoint stimulation (TEAS) against non-TEAS groups and investigated the variables that predict effective relief of upper extremity pain in cancer survivors with CIPN.Methods: We retrospectively collected data of cancer survivors who developed CIPN between May 2017 to March 2022. …”
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The Joint Association of Sleep Quality and Outdoor Activity with Asthma and Allergic Rhinitis in Children: A Cross-Sectional Study in Shanghai by Lu R, Zhang Y, Chen Y, Lyu J, Li R, Kang W, Zhao A, Ning Z, Hu Y, Lin X, Tong S, Lu Z, Li S

“…Ruoyu Lu,1,* Ye Zhang,1,* Yiting Chen,1 Jiajun Lyu,1 Rong Li,1 Wenhui Kang,1 Anda Zhao,1,2 Zidi Ning,1 Yabin Hu,3 Xiaya Lin,4 Shilu Tong,3 Zhaohui Lu,3 Shenghui Li1,5 1School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Huadong Hospital, Fudan University, Shanghai, People’s Republic of China; 3National Children’s Medical Center, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 4Hainan Branch, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Sanya, Hainan Province, People’s Republic of China; 5MOE-Shanghai Key Laboratory of Children’s Environmental Health, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaohui Lu, National Children’s Medical Center; Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, 1678 Dongfang Road, Pudong District, Shanghai, 200127, People’s Republic of China, Tel +86-18930830796, Email luzhaohui@sjtu.edu.cn Shenghui Li, School of Public Health, Shanghai Jiao Tong University School of Medicine, 227 South Chongqing Road, Huangpu District, Shanghai, 200025, People’s Republic of China, Tel +86-21-63846590, Email lsh9907@163.com; submission9907@163.comPurpose: Aiming to investigate the combined association of sleep quality and outdoor activity with the risk of asthma and allergic rhinitis in children.Patients and Methods: 16,936 children from kindergartens and primary schools in 13 administrative districts of Shanghai, China were involved in the analyses. …”
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The Role of Thickening Agent Proportions in Optimizing Nanoemulsion Gel for Dermatophytosis Treatment by Zhang X, Wu CC, Jiang H, Zhao JF, Pan ZJ, Zheng Y

“…Xiao Zhang,1,* Chen-Chen Wu,1 Hua Jiang,2 Jia-Fu Zhao,1,3 Zhong-Jian Pan,1 Yin Zheng1,3,* 1College of Animal Science, Guizhou University, Guiyang, Guizhou, People’s Republic of China; 2College of Veterinary Medicine, Gansu Agriculture University, Lanzhou, Gansu, People’s Republic of China; 3Key Laboratory of Animal Genetics, Breeding and Reproduction in The Plateau Mountainous Region, Ministry of Education, Guizhou University, Guiyang, Guizhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yin Zheng, College of Animal Science, Guizhou University, Mingyi Building (Teaching and Research Center), Room 428, West Campus of Guizhou University, Huaxi District, Guiyang City, Guizhou Province, 550025, People’s Republic of China, Email yzheng@gzu.edu.cnBackground: Adjusting thickening agent proportions in nanoemulsion gel (NG) balances its transdermal and topical delivery properties, making it more effective for dermatophytosis treatment.Methods: Carbomer 940 and α-pinene were used as model thickening agent and antifungal, respectively. …”
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Investigating the Occurrence of Soil-Transmitted Parasites Contaminating Soil, Vegetables, and Green Fodder in the East of Nile Delta, Egypt by Samah H. Yahia, Samia E. Etewa, Abd Allah A. Al Hoot, Salwa Z. Arafa, Nesreen S. Saleh, Mohamed H. Sarhan, Suzan I. Rashad, Shimaa S. Hassan

“…Data were presented in numbers and percentages. P-values equal to or less than 0.05 were considered to be statistically significant. …”
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Comprehensive Analysis of Programmed Cell Death-Related Genes in Diagnosis and Synovitis During Osteoarthritis Development: Based on Bulk and Single-Cell RNA Sequencing Data by Zhou J, Jiao S, Huang J, Dai T, Xu Y, Xia D, Feng Z, Chen J, Li Z, Hu L, Meng Q

“…JiangFei Zhou,1,* SongSong Jiao,1,* Jian Huang,2,* TianMing Dai,3,* YangYang Xu,1,* Dong Xia,4,* ZhenCheng Feng,1 JunJie Chen,1 ZhiWu Li,5 LiQiong Hu,4 QingQi Meng1,3 1Department of Orthopedics, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, 510220, People’s Republic of China; 2Qingdao Medical College, Qingdao University, Qingdao, 266071, People’s Republic of China; 3Guangzhou Institute of Traumatic Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, 510220, People’s Republic of China; 4Critical Care Medicine Department, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, 510220, People’s Republic of China; 5Department of Orthopedics, the 2nd People’s Hospital of Bijie, Guizhou, 551700, People’s Republic of China*These authors contributed equally to this workCorrespondence: LiQiong Hu; QingQi Meng, Email 13929526981@163.com; mengqingqi@jnu.edu.cnBackground: Synovitis is one of the key pathological feature driving osteoarthritis (OA) development. …”
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Interleukin-1 Receptor-Associated Kinase-3 Aggravates Neuroinflammatory Injury After Intracerebral Hemorrhage via Activation NF-κB/IL-17A Pathway in Mice by Wang J, Li Y, Tan C, Shao J, Tang W, Kong Q, Sheng W, Ding Z, Li F, Piao J, Lv D, Hu L, Wang Q, Jiang X

“…Jun Wang,1,* Yulong Li,1,* Chunyu Tan,1,* Jinlian Shao,1 Weitai Tang,2 Quan Kong,3 Wenqianjun Sheng,1 Zhiquan Ding,1 Feng Li,1 Jifeng Piao,1 Dingyi Lv,1 Libin Hu,1 Qinghua Wang,1 Xiaodan Jiang1 1Neuromedicine Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, People’s Republic of China; 2Department of Neurosurgery, The People’s Hospital of Luoding & Affiliated Luoding Hospital of Guangdong Medical University, Luoding, 527200, People’s Republic of China; 3Neurosurgery Department of Zengcheng Campus, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinghua Wang; Xiaodan Jiang, Email wqh1123@126.com; jiangxiao_dan@163.comBackground: Neuroinflammatory reactions are crucial factors in secondary brain damage following intracerebral hemorrhage (ICH). …”
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The Identification of FN1 as an Early Diagnostic Marker for Recurrent Abortion by Single-Exosome Profiling by Wang C, Lu Z, She G, Chen K, Zhou H, Zhan X, Yu H, Pi L, Zuo L, Che D

“…Chenlu Wang,1,* Zhaojin Lu,1,* Guangpeng She,2 Kaining Chen,1 Huazhong Zhou,1 Xueli Zhan,3 Hongyan Yu,1 Lei Pi,1 Liandong Zuo,4 Di Che1 1Department of Clinical Biological Resource Bank, Guangzhou Institute of Pediatrics, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, 510620, People’s Republic of China; 2Department of Laboratory Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510180, People’s Republic of China; 3Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510620, People’s Republic of China; 4Department of Andrology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, 510620, People’s Republic of China*These authors contributed equally to this workCorrespondence: Di Che, Department of Clinical Biological Resource Bank, Guangzhou Institute of Pediatrics, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, No. 9 Jinsui Road, Guangzhou, Guangdong, 510620, People’s Republic of China, Email chedi@gwcmc.org Liandong Zuo, Department of Andrology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, 9 Jinsui Road, Guangzhou, Guangdong, 510620, People’s Republic of China, Email zuold@163.comPurpose: Recurrent abortion(RA) is a prevalent adverse pregnancy event. …”
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Physicians’ Perceptions of the Quality of Palliative Care and of the Importance of Collaboration in Interdisciplinary Teams in Norwegian Nursing Homes by Skomakerstuen Ødbehr L, Hov R, Sanaker H, Sandsdalen T

“…Liv Skomakerstuen Ødbehr,1,* Reidun Hov,2,* Harald Sanaker,3,* Tuva Sandsdalen1,* 1Department of Health and Nursing Sciences, Faculty of Social and Health Sciences, University of Inland Norway, Elverum, Norway; 2Centre for Development of Institutional and Home Care Services Inland (Hedmark) Norway, Hamar Municipality, Norway; 3Municipal Medical Center, Ringsaker Municipality, Brumunddal, Norway*These authors contributed equally to this workCorrespondence: Liv Skomakerstuen Ødbehr, Faculty of Social and Health Sciences, University of Inland Norway, Post Box 400, Elverum, 2418, Norway, Tel +47 959 079 84, Email liv.odbehr@inn.noPurpose: The palliative phase of a patient’s life is often characterized by disease complexity, increasing the need for holistic care, support for the patient’s relatives, and the up-to-date knowledge of a multidisciplinary healthcare team. …”
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Klasifikasi Kelas Kata (Part-Of-Speech Tagging) untuk Bahasa Madura Menggunakan Algoritme Viterbi by Ilham Firmansyah, Putra Pandu Adikara, Sigit Adinugroho

“…The system achieved a micro average accuracy score of 0,96, and micro average precision score is equal to recall of 0,68. Precision and recall can still be improved by adding more data for training. …”
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Simultaneous Liver Venous Deprivation Following Hepatic Arterial Chemoembolization Before Major Hepatectomy for Hepatocellular Carcinoma: A New Methods to Achieve Hypertrophy Liver... by Zhang S, Song R, Hou C, Yao H, Xu J, Zhou H, Li S, Cai W, Fei Y, Meng F, Yin D, Wang J, Zhang S, Liu Y, Wang J, Liu L

“…Shenyu Zhang,1,* Ruipeng Song,1,* Changlong Hou,2,* Huanzhang Yao,1 Jun Xu,2 Hangcheng Zhou,3 Shaopeng Li,4 Wei Cai,1 Yipeng Fei,2 Fanzheng Meng,1 Dalong Yin,1 Jiabei Wang,1 Shugeng Zhang,1 Yao Liu,1 Jizhou Wang,1,5,6 Lianxin Liu1,5,6 1Department of Hepatobiliary Surgery, Centre for Leading Medicine and Advanced Technologies of IHM, the first affiliated hospital of ustc, Division of Life Sciences and Medicine, university of science and technology of china, Hefei, Anhui, 230001, People’s Republic of China; 2Department of Intervention, The First Affiliated Hospital of USTC: Anhui Provincial Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China; 3Department of Pathology, The First Affiliated Hospital of USTC: Anhui Provincial Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China; 4Department of Imaging, The First Affiliated Hospital of USTC: Anhui Provincial Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China; 5Anhui Provincial Key Laboratory of Hepatopancreatobiliary Surgery, Hefei, Anhui, 230001, People’s Republic of China; 6Anhui Provincial Clinical Research Center for Hepatobiliary Diseases, Hefei, Anhui, 230001, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lianxin Liu; Jizhou Wang, Email liulx@ustc.edu.cn; wangjoe@ustc.edu.cnPurpose: Liver venous deprivation (LVD; simultaneous portal vein embolization and hepatic vein embolization) has been the latest surgical strategy for rapid future liver remnant (FLR) hypertrophy. …”
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Effectiveness of Noninvasive Positive Pressure Ventilation Combined with Enteral Nutrition in the Treatment of Patients with Combined Respiratory Failure after Lung Cancer Surgery... by Yongjun Zhang, Lanbo Liu, Dawei Li, Dongsheng Zhou

“…A total of 82 patients with combined respiratory failure after lung cancer surgery who were treated in our hospital from March 2016∼September 2021 were selected as the research subjects, and according to the random number table method, they were equally divided into the parenteral nutrition group (n = 41) with NIPPV + parenteral nutrition support treatment and the enteral nutrition group (n = 41) with NIPPV + enteral nutrition support treatment. …”
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Inhibition of microRNA-139-5p Improves Fibroblasts Viability and Enhances Wound Repair in Diabetic Rats Through AP-1 (c-Fos/c-Jun) by Mo J, Zhang J, Meng X, Wang F, Tang W, Liu Y, Fu L, Liang F, Mo Z

“…Jiake Mo,1,2,* Jiaqi Zhang,1,2,* Xubiao Meng,3 Fang Wang,1,2 Weian Tang,1,2 Ying Liu,1,2 Lanfang Fu,3 Fang Liang,4 Zhaohui Mo1,2 1Department of Endocrinology, Third Xiangya Hospital of Central South University, Changsha, Hunan Province, People’s Republic of China; 2Diabetic Foot Research Center of Central South University, Changsha, Hunan Province, People’s Republic of China; 3Department of Endocrinology, Haikou People’s Hospital & Haikou Affiliated Hospital of Central South University Xiangya School of Medicine, Haikou, Hainan Province, People’s Republic of China; 4Department of Endocrinology, Xingtai People’s Hospital, Xingtai, Hebei Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaohui Mo; Fang Liang, Email easd04mzh@126.com; liangfang1024@163.comIntroductions: Diabetic foot ulcers (DFU) are notoriously difficult to heal, however, its underlying molecular mechanisms are unknown. …”
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Investigating Falls Risk Awareness in Hospitals Using the Self‐Awareness of Falls Risk Measure (SAFRM): Empirical Research Quantitative by Elissa Dabkowski, Simon J. Cooper, Jhodie Duncan, Karen Missen

“…Regression analyses showed that patients were more likely to overestimate their falls risk if they used anticoagulant medication and if their highest education level was less than or equal year 11. An exploratory factor analysis (EFA) revealed a three‐factor solution from section A of the SAFRM, which were labelled Physical Activity Awareness, Cognitive Awareness and Balance Awareness. …”
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α-Methyl-Tryptophan Inhibits SLC6A14 Expression and Exhibits Immunomodulatory Effects in Crohn’s Disease by Su Y, Li J, Chen Y, Bao J, Lei Z, Ma M, Zhang W, Liu Q, Xu B, Hu T, Hu Y

“…YongCheng Su,1,* Jiangquan Li,1,* Yijia Chen,2,* Jiachen Bao,2 Ziyu Lei,1 Miaomiao Ma,1 Wenqing Zhang,1 Qian Liu,3 Beibei Xu,4 Tianhui Hu,1,3 Yiqun Hu2 1Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, People’s Republic of China; 2Department of Gastroenterology, The National Key Clinical Specialty, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, People’s Republic of China; 3Integrated Chinese and Western Medicine Institute for Children Health & Drug Innovation, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, 330004, People’s Republic of China; 4Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, People’s Republic of China*These authors contributed equally to this workCorrespondence: Tianhui Hu, Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, People’s Republic of China, Email thu@xmu.edu.cn Yiqun Hu, Department of Gastroenterology, The National Key Clinical Specialty, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, People’s Republic of China, Email hyq0826@xmu.edu.cnIntroduction: Crohn’s disease (CD) is a chronic inflammatory condition of the intestines with a rising global incidence. …”
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Psychological symptoms, quality of life and dyadic relations in family members of intensive care survivors: a multicentre, prospective longitudinal cohort study by Sumeet Rai, Dale M. Needham, Rhonda Brown, Teresa Neeman, Krishnaswamy Sundararajan, Arvind Rajamani, Rakshit Panwar, Mary Nourse, Frank M. P. van Haren, Imogen Mitchell, for the PRICE study investigators

“…The family members of non-intubated ICU survivors had an equal propensity to develop long-term psychological distress and should be included in long-term outcome studies. …”
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Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation by Chen Y, Li Y, Song H, Liu X, Zhang H, Jiang J, Liu H, Zhuo R, Cheng G, Fang J, Xu L, Qi Y, Sun D

“…Yuhui Chen,1,* Ying Li,1,* Haoning Song,1,* Xiaochun Liu,1 Hongan Zhang,1 Jiaxin Jiang,2 Hongsheng Liu,2 Ribo Zhuo,1 Guoyun Cheng,1 Jia Fang,1 Lei Xu,1 Yong Qi,1 Dawei Sun1 1Department of Orthopedics and Traumatology, The Affiliated Guangdong second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, 510315, People’s Republic of China; 2Guangdong Huayi Biomedical Science and Technology Center, Guangzhou, Guangdong, 511450, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei Xu, Department of Orthopedics and Traumatology, Guangdong second Provincial General Hospital of Jinan University, No. 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, People’s Republic of China, Email orthoxl@163.com Dawei Sun, Department of Orthopedics and Traumatology, Guangdong second Provincial General Hospital of Jinan University, No. 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, People’s Republic of China, Email sundw@gd2h.org.cnBackground: A paramount issue in the realm of chronic wound healing among diabetic patients is the pervasive inflammatory response that persistently thwarts angiogenesis, thereby precipitating protracted delays in the healing process of such wounds. …”
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Determination of a normal orogenic palaeo-geothermal gradient with clay mineral and organic matter indices: a review by Rafael Ferreiro Mählmann, Meinert Rahn, Sébastien Potel, Lan Nguyen-Thanh, Rainer Petschick

“…For the detection of a poly-phase or plurifacial thermal history, several indices of clay minerals and organic matter with very different kinetics should be used, as e.g. demonstrated by strong differences in smectite content at equal VR/KI values versus structural depth. A specific interest is given to the correlation of vitrinite like solid bitumen reflectance as an alternative method to VR, the persistent preservation of liptinite macerals and the stability range of clay minerals and sub-greenschist facies critical minerals compared with VR/KI data. …”
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Severe soft tissue injuries in multiple trauma patients—a challenge we can meet? A matched-pair analysis from the TraumaRegister DGU® by Nora Kirsten, Georg Maximilian Franke, Rolf Lefering, Tim Klüter, Matthias Weuster, Michael Müller, Sebastian Lippross, Andreas Seekamp, TraumaRegister DGU®, Stefanie Fitschen-Oestern

“…Endotracheal tube insertion (27.7% vs. 30.4%, p = 0.003), catecholamine administration (6.0% vs. 8.4%, p < 0.001) and cardio-pulmonary resuscitation (1.6% vs. 2.1%, p = 0.027) were more frequent in the group with sustained soft tissue injury. Both groups were equally frequent admitted to the intensive care unit (ICU) and length of stay (LOS) at the ICU (median (quartiles) 3 (1–9) versus 3 (1–9)) did not differ significantly. …”
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