Rhein Mitigates Lung Injury in Severe Acute Pancreatitis Through the Inhibition of MARK4-Mediated Microtubule Destabilization by Sun Z, Liu J, Ge P, Cao Y, Liu J, Wen H, Luo X, Pei B, Jin Z, Li H, Xun L, Luo Y, Yang Q, Chen H

“…Zhenxuan Sun,1– 3,* Jie Liu,1– 3,* Peng Ge,1– 3,* Yinan Cao,4 Jin Liu,1– 3 Haiyun Wen,1– 3 Xinyu Luo,1– 3 Boliang Pei,1– 3 Zuocang Jin,1,3 Huijuan Li,3 Lu Xun,1– 3 Yalan Luo,5 Qi Yang,6 Hailong Chen1– 3 1Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 2Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 3Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 4Day Surgery Center, Dalian Municipal Central Hospital, Dalian, Liaoning, 116033, People’s Republic of China; 5Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hailong Chen, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Zhongshan Road 222, Dalian, Liaoning, 116011, People’s Republic of China, Tel +86 411 83635963, Fax +86 411 83622844, Email chenhailong@dmu.edu.cnPurpose: Explore the therapeutic effect and molecular mechanism of rhein on severe acute pancreatitis associated acute lung injury (SAP-ALI).Methods: The SAP-ALI rat model was constructed by retrograde injection of 5% sodium taurocholate into the pancreaticobiliary duct, and pulmonary microvascular endothelial cell (PMVEC) injury model was induced by LPS. …”
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CLEC11A-Driven Molecular Mechanisms in Intervertebral Disc Degeneration: A Comprehensive Multi-Omics Study by Jiang N, Wang Q, Hu Z, Tian X

“…Nizhou Jiang,1,* Quanxiang Wang,2,* Zhenxin Hu,3,* Xiliang Tian1 1Department of Spine Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China; 2Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China; 3Department of Spine Surgery, Peking University Fourth School of Clinical Medicine, Beijing Jishuitan Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiliang Tian, Department of Spine Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China, Email tianxiliang1983@163.comBackground: Intervertebral disc degeneration (IVDD) is a common chronic degenerative disease with a complex etiology involving genetic and environmental factors. …”
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Hippocampal Functional Radiomic Features for Identification of the Cognitively Impaired Patients from Low-Back-Related Pain: A Prospective Machine Learning Study by Yang Z, Liang X, Ji Y, Zeng W, Wang Y, Zhang Y, Zhou F

“…Ziwei Yang,1,2,* Xiao Liang,1,2,* Yuqi Ji,1,2 Wei Zeng,1,2 Yao Wang,1,2 Yong Zhang,3 Fuqing Zhou1,2 1Jiangxi Provincial Key Laboratory for Precision Pathology and Intelligent Diagnosis, Department of Radiology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 2Neuroradiology Laboratory, Jiangxi Province Medical Imaging Research Institute, Nanchang, 330006, People’s Republic of China; 3Department of Pain Clinic, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, 330006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yong Zhang, Department of Pain Clinic, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwaizheng Street, Nanchang, Jiangxi, 330006, People’s Republic of China, Tel +86 791 8869 5036, Email zy830226@163.com Fuqing Zhou, Jiangxi Provincial Key Laboratory for Precision Pathology and Intelligent Diagnosis, Department of Radiology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwaizheng Street, Nanchang, Jiangxi, 330006, People’s Republic of China, Tel +86 791 8869 5132, Email ndyfy02301@ncu.edu.cnPurpose: To investigate whether functional radiomic features in bilateral hippocampi can identify the cognitively impaired patients from low-back-related leg pain (LBLP).Patients and Methods: For this retrospective study, a total of 95 clinically definite LBLP patients (40 cognitively impaired patients and 45 cognitively preserved patients) were included, and all patients underwent functional MRI and clinical assessments. …”
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Increased Mortality After Lower Extremity Amputation in a Danish Nationwide Cohort: The Mediating Role of Postoperative Complications by Brix ATH, Petersen TG, Nymark T, Schmal H, Lindberg-Larsen M, Rubin KH

“…Anna Trier Heiberg Brix,1,2 Tanja Gram Petersen,3 Tine Nymark,1,2 Hagen Schmal,1,4 Martin Lindberg-Larsen,1,2 Katrine Hass Rubin2,3 1Department of Orthopedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark; 2Department of Clinical Research, University of Southern Denmark, Odense, Denmark; 3Research Unit OPEN, Odense University Hospital and University of Southern Denmark, Odense, Denmark; 4Department of Orthopedics and Traumatology, University Medical Center Freiburg, Freiburg, GermanyCorrespondence: Anna Trier Heiberg Brix, Department of Orthopedic Surgery and Traumatology, Odense University Hospital, J. …”
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Genetic Associations Between Specific Sleep-Related Phenotypes and Idiopathic Sudden Sensorineural Hearing Loss: A Mendelian Randomization Analysis by Li M, He J, Liang Y, Zou F, Gou C, Lv J, Zhang X, Li D, Yu Z

“…Man Li,1,* Jinbo He,2,* Yiting Liang,3 Fan Zou,1 Changlong Gou,4 Jing Lv,2 Xicheng Zhang,5 Dan Li,6 Zizhong Yu1 1Department of Otolaryngology, Head and Neck Surgery, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People’s Republic of China; 2Department of Anesthesiology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People’s Republic of China; 3First Clinical College, Hubei University of Medicine, Shiyan, 442000, People’s Republic of China; 4Department of Ultrasound Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People’s Republic of China; 5Biomedical Engineering College, Hubei University of Medicine, Shiyan, 442000, People’s Republic of China; 6Clinical Molecular Diagnostic Center, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zizhong Yu, Department of Otolaryngology, Head and Neck Surgery, Taihe Hospital, Hubei University of Medicine, No. 32 Renmin South Road, Maojian District, Shiyan, Hubei, 442000, People’s Republic of China, Tel +86-719-8801459, Email yurick0994@163.com Dan Li, Clinical Molecular Diagnostic Center, Taihe Hospital, Hubei University of Medicine, No. 32 Renmin South Road, Maojian District, Shiyan, Hubei, 442000, China, Tel +86-719-8801881, Email lidan198016@163.comPurpose: The relationship between idiopathic sleep-related phenotypes (SRPs) and sudden sensorineural hearing loss (ISSNHL) remains unclear. …”
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IRF3 Promotes Production of IL-6 and Nitric Oxide but Represses CCL22 in RAW264.7 Macrophage Cells Exposed to Lipopolysaccharides in Culture by Moore TC, Pinkerton TS, Petro TM

“…Tyler C Moore,1 Terrence Scott Pinkerton,1 Thomas M Petro2 1Department of Biology, College of Science and Technology, Bellevue University, Bellevue, NE, 68005, USA; 2Department of Oral Biology, University of Nebraska Medical Center, Lincoln, NE, 68583, USACorrespondence: Thomas M Petro, Department of Oral Biology, University of Nebraska Medical Center, College of Dentistry, 4000 East Campus Loop South, Lincoln, NE, 68583, USA, Email tpetro@unmc.eduIntroduction: Macrophage responses to lipopolysaccharides (LPS) drive inflammatory diseases, such as periodontitis, with production of IL-6 and Nitric Oxide (NO). …”
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Advancements in Liposomal Nanomedicines: Innovative Formulations, Therapeutic Applications, and Future Directions in Precision Medicine by Izadiyan Z, Misran M, Kalantari K, Webster TJ, Kia P, Basrowi NA, Rasouli E, Shameli K

“…Zahra Izadiyan,1 Misni Misran,1 Katayoon Kalantari,2 Thomas J Webster,3,4 Pooneh Kia,5 Noor Ashyfiyah Basrowi,1 Elisa Rasouli,6 Kamyar Shameli7 1Department of Chemistry, Universiti Malaya, Kuala Lumpur, Malaysia; 2Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 3Biomedical Engineering, Hebei University of Technology, Tianjin, People’s Republic of China; 4School of Engineering, Saveetha University, Chennai, India; 5Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 6Department of Electrical and Electronics Engineering, Nanyang Technological University, Nanyang, Singapore; 7School of Medicine, Institute of Virology, Technical University of Munich, Munich, GermanyCorrespondence: Zahra Izadiyan; Kamyar Shameli, Email zahra_izadiyan@yahoo.com.my; kamyarshameli@gmail.comAbstract: Liposomal nanomedicines have emerged as a pivotal approach for the treatment of various diseases, notably cancer and infectious diseases. …”
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Economic Studies by A. V. Kholopov

“…Established in 1993, the Department of Risk Management and Insurance is headed by Professor R.T. …”
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خدمات المعلومات المقدمة عبر مکتبى التواصل Library Liaison بجامعة الامام عبد الرحمن بن فیصل :دراسة حالة by د. سفانة عبد القادر زیدان

“…The total number (324) users, who responded to the searchinstrument correctly (in electronic form and printed), of (116) faculty membersand research students; 35.8% from users.The results of the study revealed that the research community holds theopinion that the services to be provided by the liaison are of great importance inthe following fields: collections Development for the academic departments,providing reference services and specialized research services, providing Libraryinstruction services with the academic departments, providing scholarcommunication services, and finally providing education and training services. all these responses are very high, which reflects the importance of these activitiesand services provided by the liaison to faculty members and researchers. …”
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Systematic Analysis of E3 Ligase-Related Genes Identified UBE2L3 as a Prognostic Biomarker Associated With Drug Resistance in Acute Myeloid Leukemia by Ling C, Cao N, Wang H, Wan Y, Liang X, Guo J, Xiao M, Zhang Q, Zhai Z

“…Chun Ling,1,2 Nengneng Cao,1 Huiping Wang,1 Yang Wan,1 Xue Liang,1 Jinjing Guo,1 Meng Xiao,1 Qiguo Zhang,2 Zhimin Zhai1 1Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230000, People’s Republic of China; 2Department of Hematology, Affiliated Chuzhou Hospital of Anhui Medical University, First People’s Hospital of Chuzhou, Chuzhou, Anhui, 239001, People’s Republic of ChinaCorrespondence: Zhimin Zhai, Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230000, People’s Republic of China, Email zzzm886@163.comBackground: Acute Myeloid Leukemia (AML) is a prevalent neoplastic disorder. …”
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Physicians’ perception towards continuing professional development in government teaching hospitals of Addis Ababa, Ethiopia-mixed method design by Merahi Kefyalew Merahi, Walelegn Worku Yallew

“…It also showed that the department of healthcare Professionals had a statistically significant association with the perception of continuing professional development. …”
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Impact of Seasonal Variations on Semen Parameters: A Retrospective Analysis of Data from Subjects Attending a Tertiary Care Fertility Centre by Anitha Malathi, Ramesh P. Iyer, Reji Mohan, Sheila Balakrishnan

“…Materials and Methods: The data were collected from records of all infertile couples registered for the treatment in the department during the study period. Semen analysis reports of male partners of all infertile couples attending outpatient department of the Reproductive Medicine Department during the 4-year period from January 2019 to December 2022 were collected. …”
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Epidemiology, Clinical Characteristics and Treatment Outcomes of Acinetobacter baumannii Infection at a Regional Hospital in Thailand by Sakulkonkij P, Bruminhent J

“…Parichart Sakulkonkij,1 Jackrapong Bruminhent2 1Division of Infectious Diseases, Internal Medicine Department, Lampang Hospital, Lampang, Thailand; 2Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Parichart Sakulkonkij, Division of Infectious Diseases, Internal Medicine Department, Lampang Hospital, Lampang, Thailand, Email parichart1507@gmail.comObjective: This retrospective cohort study evaluated the treatment outcome of Acinetobacter baumannii infection.Methods: In this retrospective cohort study, 476 patients with Acinetobacter baumannii (A. baumannii) infection who were admitted to the internal medicine ward at Lampang Hospital, Lampang, Thailand, from 1 January 2020 to 31 December 2020 were enrolled. …”
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Ukrainian SSR police activities in combating crime in the late 1950s by V. A. Grechenko

“…Orientations in their structure and content were slightly less administrative than directives, as they were not signed by the Minister of the Interior, but by the Deputy Minister of Police and at the same time the Head of the Police Department of the Ministry of Internal Affairs of the Ukrainian SSR or one of the Interior Ministry departments. …”
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Burnout Syndrome among Emergency Physicians and Nurses in Abha and Khamis Mushait Cities, Aseer Region, Southwestern Saudi Arabia by Abdulghani M. Alqahtani, Nabil J. Awadalla, Safar A. Alsaleem, Awad S. Alsamghan, Mohammed Abadi Alsaleem

“…To explore the magnitude and determinants of burnout among emergency physicians and nurses working at emergency departments of hospitals in Abha and Khamis Mushait cities. …”
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The effect of educational programs on parents’ knowledge, behavior, and practices regarding aluminum phosphide poisoning and its first-aid measures by Mabrouka Attia Ali Nada, Ahmed Kamal Eldin Elsayed Elfeky, Hamida Ahmed Mustafa Darweesh, Farida Khalil Ibrahim Mohamed, Loujain Saud Sharif, Faten Shawky Kandil, Fatma Ahmed Elsobky, Samah Abdallah Mohamed Amer

“…Children (n = 98) who met the inclusion criteria (aged between 0 and 18 years and who experienced accidental or suicidal aluminum phosphide poisoning) were recruited from the inpatient clinical toxicology department ward, intensive care unit in the emergency department, and critical care unit of Menoufia University Hospital. …”
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The Effect of Task Cognitive Difficulty on Perceptual-Cognitive Indicators: Evidence on the Relationship Between Challenge Point Framework (CPF) and Cognitive Development in Table... by Taghi MM, Aghdaei M, Farsi A, Badicu G, de Sousa Fernandes MS, Yagin FH, Ardigò LP

“…Mahya Mohamad Taghi,1 Mahin Aghdaei,1 Alireza Farsi,1 Georgian Badicu,2 Matheus Santos de Sousa Fernandes,3 Fatma Hilal Yagin,4 Luca Paolo Ardigò5 1Faculty of Sports and Health Sciences, Shahid Beheshti University, Tehran, Iran; 2Department of Physical Education and Special Motricity, Transilvania University of Brasov, Brasov, Romania; 3Instituto Keizo Asami, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil; 4Department of Biostatistics and Medical Informatics, Faculty of Medicine, Inonu University, Malatya, Turkey; 5Department of Teacher Education, NLA University College, Oslo, NorwayCorrespondence: Luca Paolo Ardigò; Mahya Mohamad Taghi, Email luca.ardigo@nla.no; mahya.mohamadtaghi@yahoo.comIntroduction: Motor learning, in addition to influencing the practice of physical activity, affects cognitive skills related to prediction and decision. …”
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The outline of Levas Vladimirovas' professional career by Genovaitė Raguotienė

“…He was the first head of the Department of Library Science (1952-1964) and later the Department of Library and Information Science (1970-1973). …”
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Attitudes and knowledge for CBT-based psychotherapy among medical students and residents in China: a survey study by Yinan Ding, Tao Pei, Pu Peng, Jiashu Yao, Jinsong Tang, Yanhui Liao

“…Participants from psychiatric departments (M = 33.85, SD = 25.89) understood more psychotherapy than those from non-psychiatric departments (M = 20.98, SD = 19.20), t(147) = 3.46, p < .001. …”
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Determinants of Demoralization Syndrome and Social Support Among Patients with Breast Cancer: A Cross-Sectional Study by Yang L, Song LX, Zhang L, Yang Y, Zhang YM

“…Li Yang,1,2 Ling-Xia Song,1 Lin Zhang,1,2 Yan Yang,1 Yong-Mei Zhang1 1Department of Nursing, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, People’s Republic of China; 2Department of General Surgery, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, People’s Republic of ChinaCorrespondence: Yong-Mei Zhang, Department of Nursing, The Affiliated Hospital of Zunyi Medical University, No. 149, Dalian Road, Huichuan District, Zuny, GuiZhou, People’s Republic of China, Tel +86 15185210524, Fax +86 851-28608909, Email 583726149@qq.comObjective: This study aimed to assess the determinants of demoralization syndrome among patients with breast cancer (BC) in the southwestern region of China.Methods: This investigation constituted a single-center cross-sectional study in which 176 patients with BC were surveyed through a questionnaire covering the current status of demoralization syndrome and social support.Results: Majority of patients with BC developed moderate-to-severe levels of demoralization. …”
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