Effect of Kinases in Extracellular Vesicles from HIV-1-Infected Cells on Bystander Cells by Gifty A. Mensah, Anastasia Williams, Pooja Khatkar, Yuriy Kim, James Erickson, Alexandra Duverger, Heather Branscome, Kajal Patil, Hafsa Chaudhry, Yuntao Wu, Olaf Kutsch, Fatah Kashanchi

“…Although great strides have been made in treatment options for HIV-1, and our understanding of the HIV-1 life cycle has vastly improved since the start of this global health crisis, a functional cure remains elusive. One of the main barriers to a cure is latency, which allows the virus to persist despite combined antiretroviral therapy (cART). …”
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Generation of Transplantable Beta Cells for Patient-Specific Cell Therapy by Xiaojie Wang, Daniel L. Metzger, Mark Meloche, Jianqiang Hao, Ziliang Ao, Garth L. Warnock

“…Islet cell transplantation offers a potential cure for type 1 diabetes, but it is challenged by insufficient donor tissue and side effects of current immunosuppressive drugs. …”
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From the Cytoplasm into the Nucleus—Hepatitis B Virus Travel and Genome Repair by Johan Ringlander, Gustaf E. Rydell, Michael Kann

“…Understanding the intracellular transport and genome repair mechanisms of HBV is crucial for developing new drugs, which—in combination with immune modulators—may contribute to potential cures. This review will explore the current knowledge of HBV intracytoplasmic and nuclear transport, as well as genome repair processes, while drawing comparisons to other viruses with nuclear replication.…”
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Technical studies about the prestressed insulation cylinder of HL-3 tokamak's center-post by Yin Qiu, Ming Li, Xiaolong Liu, Qinghua Ren, Tao Lin, Jian Liu

“…This paper describes the results of the technical studies carried out during the development of the insulation cylinder, including material selection, parameter calculation, enlacing tests and curing tests.…”
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Treatment and Prevention of Osteoarthritis through Exercise and Sports by Victor Valderrabano, Christina Steiger

“…To date, the pathogenesis of the disease and the link between muscle function and OA is not entirely understood. As there is no known cure for OA, current research focuses on prevention and symptomatic treatment of the disorder. …”
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Secrecy outage probability based access strategy for device-to-device communication underlaying cellular networks by Ya-jun CHEN, Xin-sheng JI, Kai-zhi HUANG, Xiao-lei KANG

“…A secure access strategy for D2D (device-to-device) communications underlaying cellular networks based on the secrecy outage probability was proposed.Firstly,the secrecy outage probability in the worst case was derived and a transmission power optimization scheme for D2D pairs was given.An access control strategy was further presented to allow the D2D pair with the minimum secrecy outage probability to reuse the cellular resource,which improved the se-cure communications for D2D links and cellular uplinks.Finally,simulation results showed that the proposed scheme was effective.…”
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A Challenging Case of Multifocal Mycobacterium marinum Osteoarticular Infection in a Patient with Anorexia Nervosa by Katie Sharff, Zaw Min, Nitin Bhanot

“…Aggressive surgical intervention in conjunction with multiple antimicrobial agents helped cure the infection.…”
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Advances in Pathogenesis of Sjögren’s Syndrome by Yao Tian, Hongyi Yang, Na Liu, Yan Li, Jie Chen

“…At present, there is no cure for SS, and the treatment options are extremely limited. …”
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The Mechanical Behavior of Fiber Reinforced PP ECC Beams under Reverse Cyclic Loading by Yaw ChiaHwan, Han JianBo

“…The mechanical properties of FRP reinforced PP ECC beams and coupon RC beam under reverse cyclic load controlled by displacement are investigated. Curing ages, reinforcement ratio, and volume fraction of PP fiber are parameters under survey. …”
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Radical Resection of a Late-Relapsed Testicular Germ Cell Tumour: Hepatectomy, Cavotomy, and Thrombectomy by C. Ní Leidhin, C. E. Redmond, A. M. Cahalane, H. M. Heneghan, R. Motyer, E. R. Ryan, E. Hoti

“…Aggressive surgical resection confers the greatest chance of cure in this patient group. We present the case of a late and extensively relapsed nonseminomatous germ cell tumour with thrombus present along the entire length of the inferior vena cava, as well as in the right hepatic vein. …”
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T-Cell Lymphoblastic Leukemia/Lymphoma: Relapse 16 Years after First Remission by Lauren Elreda, Manpreet Sandhu, Xinlai Sun, Wondwessen Bekele, Alice J. Cohen, Maya Shah

“…The relapse rate after 3 years has been reported to steadily decrease over time yet does not parallel with cure. We report a case of a 26-year-old female with T-LBL and relapse 16 years after her first remission with successful treatment with HyperCVAD and L-asparaginase.…”
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Effect of Initial Backfill Temperature on the Deformation Behavior of Early Age Cemented Paste Backfill That Contains Sodium Silicate by Aixiang Wu, Yong Wang, Bo Zhou, Jiahua Shen

“…Results show that the stress-strain relationship and the modulus of elasticity behavior of CPB are significantly affected by the curing time and initial temperature of CPB. Additionally, the relationship between the modulus of elasticity and unconfined compressive strength (UCS) and the degree of hydration was evaluated and discussed. …”
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HIGH STRENGTH-GEOPOLYMER BUILDING MATERIAL by LUCIAN PAUNESCU, ENIKÖ VOLCEANOV, BOGDAN-VALENTIN PAUNESCU

“… New geopolymer concrete with high mechanical strength - 58.9 MPa after 28 days of curing - was experimentally made under environmental friendly and economic conditions. …”
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A Gastroenterologist’s Perspective of The Medical Management of Patients with Crohn’s Disease and Ulcerative Colitis by ABR Thomson

“…These objectives include to improve the quality of life, to improve symptoms, to improve nutrition and reduce the risk of nutritional deficiencies, to reduce the frequency and severity of recurrences, to reduce complications, including the need for surgery, and to cure the disease. Medical therapy potentially helps to achieve all of these objectives for sufferers of IBD, except the last one – until the pathogenesis of the recurrent or continuous episodes of bowel inflammation is better understood, this last objective will remain "a riddle, wrapped in a mystery, inside an enigma".…”
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Nodular Fasciitis Complicating a Staged Surgical Excision of Dermatofibrosarcoma Protuberans by C. Helen Malone, Brandon Goodwin, Richard F. Wagner, Vicente Resto, Brent Kelly

“…Fortunately, Mohs micrographic surgery yields excellent cure rates for this neoplasm due to contiguous tumor spread and meticulous tumor mapping and margin analysis. …”
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Antibacterial Potency of Honey by Najla A. Albaridi

“…As a result, several ancient methods have been re-evaluated and the substances/procedures employed historically to cure diseases are now attracting renewed scientific attention. …”
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Intravenous to Oral Stepdown Antibiotic Therapy: Another Cost-Effective Strategy in an Era of Shrinking Health Care Dollars by Thomas J Louie

“…The rapid transition from intravenous to oral antimicrobial therapy in hospitalized patients is being catalyzed by the need to gain further efficiencies in health care delivery without Compromising patient cure. The successful transition to oral therapy reduces complication from intravenous access devices. reduces cost of therapy and facilitates early discharge. both older and newer antimicrobials can be used as stepdown therapy. …”
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Mechanical and Thermal Properties of Shale Ceramsite Concrete: Experimental Study on the Influence Law due to Microencapsulated Phase-Change Material Content and Phase-Change Cycle... by Weihua Ding, Lin Zhu, Hu Li, Bin Hou, Fan Yang

“…When the MPCM content reaches 10%, the compressive and tensile strengths of MPCM-LWAC decreased, respectively, by 45.49% and 52.63% than the LWAC without MPCM. (2) Under heating and curing condition, the corresponding maximum specific heat capacity of LWAC with 10% MPCM is 328.35% and 249.50% higher than the LWAC without MPCM, respectively, and the average specific heat capacities increase 71.21% and 44.94%, respectively. (3) The melting enthalpy of MPCM-LWAC is slightly larger than the curing enthalpy, and the difference is more noticeable with the increase of MPCM content. …”
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Early initiation of ceftaroline-based combination therapy for methicillin-resistant Staphylococcus aureus bacteremia by Addison S. Hicks, Mackenzie A. Dolan, Megan D. Shah, Sarah E. Elwood, James A. Platts-Mills, Gregory R. Madden, Zachary S. Elliott, Joshua C. Eby

“…Time to microbiological cure was longer with combination therapy (mean difference 1.50 days, 95% CI 0.60, 2.41). …”
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