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1301
Investigating the Effect of Heavy Metals in Water Used for Concrete Production: A Case Study of Kabale.
Published 2025“…The study investigated the compressive strength, water absorption, and workability of cubes made with water containing various concentrations of heavy metals that are of copper, Lea,d, and iron, comparing them to cubes made with distilled water and cured under portable water at room temperature. OPC was used in the production of concrete cube specimens. …”
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1302
A strategy for selective screening of dual-target bioactive compounds against hypertrophic scar through inhibiting angiotensin II type 1 receptor while stimulating type 2 receptor...
Published 2025-01-01“…Abstract Background Cutaneous hypertrophic scar is a fibro-proliferative hard-curing disease. Recent studies have proved that antagonists of angiotensin II type 1 receptor (AT1R) and agonists of type 2 receptor (AT2R) were able to relieve hypertrophic scar. …”
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1303
Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival
Published 2025-02-01“…Abstract Background The immune evasion and prolonged survival of Staphylococcus aureus (S. aureus) within macrophages are key factors contributing to the difficulty in curing osteomyelitis. Although macrophages play a vital role as innate immune cells, the mechanisms by which S. aureus survives within them and suppresses host immune functions remain incompletely understood. …”
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1304
Comparative Analysis of 95 Patients with Different Severity in the Early Outbreak of COVID-19 in Wuhan, China
Published 2020-01-01“…All common and severe patients (100%) were cured and discharged from the hospital, while 10 (71.4%) of 14 critical patients died. …”
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Circulating Tumor DNA Detection for Recurrence Monitoring of Stage I Non‐Small Cell Lung Cancer Treated With Microwave Ablation
Published 2025-01-01“…Patients with undetectable ctDNA within 1 h after MWA are determined to be clinically cured. Risk stratification based on ctDNA test results helps to differentiate high‐risk patients.…”
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1306
Epidemiology of notifiable outbreaks in different hospital units in Saudi Arabia: A national descriptive study
Published 2025-03-01“…Approximately 33.7 % of the patients died, 24.1 % cured, 19.3 % transferred, and 17.0 % discharged. …”
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The role of mNGS in the diagnosis of talaromycosis and case series
Published 2025-02-01“…One of them was mix infected by fungi, bacteria, Mycobacterium tuberculosis and virus, improved by voriconzole and followed by introconaole. The other case was cured by introconazole. Conclusions Traditional diagnostic methods are limited by factors such as the long time and low sensitivity of fungal culture, the effect of prior antibiotic treatment, the invasiveness and complexities of tissue biopsies, and so on. …”
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Use of approved cefazolin based intramammary dry goat treatment and its effects on the milk microbiota
Published 2025-01-01“…Abstract Intramammary dry-off treatment is widely considered an effective method for preventing and curing intramammary infection (IMI) in lactating cows; however, it is not commonly used in small ruminants like goats. …”
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1309
Plasma Iron Levels at Early Breast Cancer Diagnosis Are Associated With Development of Secondary Metastases: A Single-Center Retrospective Cohort Study
Published 2025-02-01“…Although most early-stage patients are cured, 20% to 30% develop metastases, significantly reducing survival rates. …”
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1310
Description of the Serological Response After Treatment of Chronic Imported Schistosomiasis
Published 2025-01-01“…All symptomatic cases were clinically cured. Conclusions: Serial serological determinations could be helpful for monitoring chronic schistosomiasis in non-endemic regions. …”
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1311
The Long-Term Change of Arrhythmias after Transcatheter Closure of Perimembranous Ventricular Septal Defects
Published 2021-01-01“…Serious arrhythmias that appear early after transcatheter pmVSD closure may impose a risk of recurrence although they have been cured already. Close attention should be paid to the changes of cardiac function in patients with CLBBB after VSD closure, and the severity of such arrhythmia should be taken seriously and reexamined.…”
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Survival Status and Predictors of Mortality among Multidrug-Resistant Tuberculosis Patients in Saint Peter’s Specialized Hospital, Addis Ababa, Ethiopia
Published 2021-01-01“…During the follow-up period, 315 (65.1%) patients were cured, 125 (25.8%) completed treatment, 24 (5%) died, and 20 (4.1%) were lost to follow-up. …”
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1313
Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study
Published 2022-06-01“…More than half of the participants (55%) did not know that asthma cannot be cured. The administration of educational intervention protocols resulted in significantly improved level of knowledge of asthma self-management (<0.001) in the treatment group (mean ASMQ score improved from 4.20 to 9.77).Conclusion On baseline visit, patients possessed a poor knowledge about asthma self-management. …”
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1314
Assessing the visibility and public engagement of bone marrow and stem cell transplantation research: An altmetric analysis
Published 2025-02-01“…Background: Bone marrow and stem cell transplantation have led to significant advancements in modern medicine, offering potential cures for various hematological disorders and specific cancers. …”
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1315
Penggunaan Obat Antihipertensi pada Pasien Hipertensi Esensial di Poliklinik Ginjal Hipertensi RSUP DR. M. Djamil Tahun 2011
Published 2014-01-01“…<br />Kata kunci: obat antihipertensi, hipertensi, diuretik</p><p>Abstract<br />Hypertension can not be cured and is closely related to a decrease in life expectancy. …”
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1316
Sistem Identifikasi Penyakit Paru Obstruktif Kronik (PPOK) Berdasarkan Suara Paru-Paru Menggunakan Jaringan Saraf Tiruan Berbasis Raspberry Pi
Published 2023-02-01“…COPD is a progressive disease that cannot be cured and will get worse over time. One way that is commonly used by doctors to diagnose lung conditions is to use a stethoscope. …”
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Analisis Tren dan Perkiraan Pandemi COVID-19 di Indonesia Menggunakan Peramalan Metode Prophet :Sebelum dan Sesudah Aturan New Normal
Published 2022-02-01“…This paper aims to facilitate a comparison between the PSBB and New Normal regulations on the development of the number of Covid-19 cases in Indonesia by mapping the cumulative number of cases (active, cured, confirmed and death cases). The Prophet method is used to predict confirmed cases and deaths within the next 30 days. …”
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CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma
Published 2022-03-01“…Targeting CD25 high, antigen-engaged Treg with a depleting anti-CD25 ICI, achieved complete cures in 100% of mice with triple therapy. Transcriptomic analysis confirmed reduction in Foxp3 on addition of anti-CD25 to HSV/BRAFi, as well as increases in expression of genes reflecting interferon signaling and cytotoxic activity.Conclusions Combination HSV/BRAFi is an immunogenic therapy for BRAF mutant melanoma, but cannot fully control tumors. …”
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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity
Published 2021-10-01“…In an immunocompetent mouse glioblastoma model mimicking low or absent NKG2DL expression, the combination of NKAR-NK-92 cells and NKAB-ErbB2 effectively suppressed outgrowth of ErbB2-positive tumors, resulting in treatment-induced endogenous antitumor immunity and cures in the majority of animals.Conclusions Our results demonstrate that combining an NKAB antibody with effector cells expressing an activating NKAR receptor represents a powerful and versatile approach to simultaneously enhance tumor antigen-specific as well as NKG2D-CAR and natural NKG2D-mediated cytotoxicity, which may be particularly useful to target tumors with heterogeneous target antigen expression.…”
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Elevated D-dimer on admission may predict poor prognosis in childhood influenza associated encephalopathy
Published 2025-01-01“…In the univariate analysis, the poor prognosis group compared with the clinically cured group showed a significant increase in the number of days of hospitalization (3.0 vs. 9.5 days, P < 0.001), high-sensitivity C-reactive protein (6.80 vs. 1.88 mg/L, P = 0.003), interleukin-6 (20.26 vs. 8.24 pg/mL, P = 0.001), interleukin-10 (11.75 vs. 4.72 pg/mL, P = 0.003), alanine aminotransferase (104.0 vs. 20.0 U/L, P = 0.011), aspartate azelotransferase (186.5 vs. 37.0 U/L, P = 0.003), serum albumin (37.99 vs. 40.76 g/L, P = 0.042), prothrombin time (13.2 vs. 11.4 s, P = 0.017), D-dimer (4.34 vs. 0.44 mg/L FEU, P < 0.001), peripheral blood CD19 B-cell count (35.11 vs. 32.75 cells/µL, P = 0.018), and cerebrospinal fluid chloride (126.82 vs. 125.50 mmol/L, P = 0.027) were statistically different in the above 11 indicators. …”
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