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  1. 1301

    Investigating the Effect of Heavy Metals in Water Used for Concrete Production: A Case Study of Kabale. by Bwengye, Felix

    Published 2025
    “…The study investigated the compressive strength, water absorption, and workability of cubes made with water containing various concentrations of heavy metals that are of copper, Lea,d, and iron, comparing them to cubes made with distilled water and cured under portable water at room temperature. OPC was used in the production of concrete cube specimens. …”
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    Thesis
  2. 1302

    A strategy for selective screening of dual-target bioactive compounds against hypertrophic scar through inhibiting angiotensin II type 1 receptor while stimulating type 2 receptor... by Lejing Qu, Meizhi Jiao, Zilong Zhang, Yuanyuan Ou, Xue Zhao, Yajun Zhang, Xinfeng Zhao

    Published 2025-01-01
    “…Abstract Background Cutaneous hypertrophic scar is a fibro-proliferative hard-curing disease. Recent studies have proved that antagonists of angiotensin II type 1 receptor (AT1R) and agonists of type 2 receptor (AT2R) were able to relieve hypertrophic scar. …”
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    Article
  3. 1303

    Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival by Yaji Yang, Haotian Zhou, Feilong Li, Yanhao Zhang, Jianye Yang, Yidong Shen, Ning Hu, Quanming Zou, Leilei Qin, Hao Zeng, Wei Huang

    Published 2025-02-01
    “…Abstract Background The immune evasion and prolonged survival of Staphylococcus aureus (S. aureus) within macrophages are key factors contributing to the difficulty in curing osteomyelitis. Although macrophages play a vital role as innate immune cells, the mechanisms by which S. aureus survives within them and suppresses host immune functions remain incompletely understood. …”
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    Article
  4. 1304

    Comparative Analysis of 95 Patients with Different Severity in the Early Outbreak of COVID-19 in Wuhan, China by Fang He, Xue-feng Ding, Meng Cao, Hai-ying Gong, Xiang-zhen Fu, Jie Luo, Kui Liu, Zhou-zhou Tian, Lin Luo, Yu-yuan Fan, Ting Li, Qian-Jing Yao, Xiao-ju Chen, Xiang-lin Duan, Li Chen, Li Jiang

    Published 2020-01-01
    “…All common and severe patients (100%) were cured and discharged from the hospital, while 10 (71.4%) of 14 critical patients died. …”
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    Article
  5. 1305

    Circulating Tumor DNA Detection for Recurrence Monitoring of Stage I Non‐Small Cell Lung Cancer Treated With Microwave Ablation by Lin Cheng, Sheng Xu, Yu‐feng Wang, Sheng‐wei Li, Bin Li, Xiao‐Guang Li

    Published 2025-01-01
    “…Patients with undetectable ctDNA within 1 h after MWA are determined to be clinically cured. Risk stratification based on ctDNA test results helps to differentiate high‐risk patients.…”
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    Article
  6. 1306
  7. 1307

    The role of mNGS in the diagnosis of talaromycosis and case series by Jing Zhao, Hui-Ting Su, Dong Zhang, Xue-Tong Li, Min-Ya Lu, Juan Du, Jia-Yu Guo, Yi Gao, Xin-Fei Chen, Dong-Hua Wen, Shi-Yu Jia, Yao Wang, Qi-Wen Yang

    Published 2025-02-01
    “…One of them was mix infected by fungi, bacteria, Mycobacterium tuberculosis and virus, improved by voriconzole and followed by introconaole. The other case was cured by introconazole. Conclusions Traditional diagnostic methods are limited by factors such as the long time and low sensitivity of fungal culture, the effect of prior antibiotic treatment, the invasiveness and complexities of tissue biopsies, and so on. …”
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    Article
  8. 1308

    Use of approved cefazolin based intramammary dry goat treatment and its effects on the milk microbiota by Delower Hossain, Filippo Biscarini, Valentina Monistero, Paola Cremonesi, Bianca Castiglioni, Anoar Jamai Masroure, Alessandro Marinoni, Sara Fusar Poli, Matteo Mezzetti, Maria Filippa Addis, Valerio Bronzo, Erminio Trevisi, Paolo Moroni

    Published 2025-01-01
    “…Abstract Intramammary dry-off treatment is widely considered an effective method for preventing and curing intramammary infection (IMI) in lactating cows; however, it is not commonly used in small ruminants like goats. …”
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    Article
  9. 1309
  10. 1310

    Description of the Serological Response After Treatment of Chronic Imported Schistosomiasis by Marta González-Sanz, Irene Martín-Rubio, Oihane Martín, Alfonso Muriel, Sagrario de la Fuente-Hernanz, Clara Crespillo-Andújar, Sandra Chamorro-Tojeiro, Begoña Monge-Maíllo, Francesca F. Norman, José A. Pérez-Molina

    Published 2025-01-01
    “…All symptomatic cases were clinically cured. Conclusions: Serial serological determinations could be helpful for monitoring chronic schistosomiasis in non-endemic regions. …”
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    Article
  11. 1311

    The Long-Term Change of Arrhythmias after Transcatheter Closure of Perimembranous Ventricular Septal Defects by Hongyan Zheng, Aiwen Lin, Li Wang, Yukai Xu, Zhiwei Zhang

    Published 2021-01-01
    “…Serious arrhythmias that appear early after transcatheter pmVSD closure may impose a risk of recurrence although they have been cured already. Close attention should be paid to the changes of cardiac function in patients with CLBBB after VSD closure, and the severity of such arrhythmia should be taken seriously and reexamined.…”
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    Article
  12. 1312

    Survival Status and Predictors of Mortality among Multidrug-Resistant Tuberculosis Patients in Saint Peter’s Specialized Hospital, Addis Ababa, Ethiopia by Mikyas Arega Muluneh, Abayneh Birlie Zeru, Behailu Tariku Derseh, Abebaw Molla Kebede

    Published 2021-01-01
    “…During the follow-up period, 315 (65.1%) patients were cured, 125 (25.8%) completed treatment, 24 (5%) died, and 20 (4.1%) were lost to follow-up. …”
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    Article
  13. 1313

    Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study by Ahmad Khan, Saima Mushtaq, Amjad Khan, Nafees Ahmad, Shahzadi Sidra Saleem, Rubina Aman, Shahzadi Sadia Saleem, Ayesha Bibi, Saifullah Mehsud, Ivan R Green, Sheikh Abdur Rashid, Kifayat Ullah Shah

    Published 2022-06-01
    “…More than half of the participants (55%) did not know that asthma cannot be cured. The administration of educational intervention protocols resulted in significantly improved level of knowledge of asthma self-management (<0.001) in the treatment group (mean ASMQ score improved from 4.20 to 9.77).Conclusion On baseline visit, patients possessed a poor knowledge about asthma self-management. …”
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    Article
  14. 1314

    Assessing the visibility and public engagement of bone marrow and stem cell transplantation research: An altmetric analysis by Mohammad Ahmadian, Shaban Alizadeh, Azadeh Omidkhoda, Fatemeh Sheikhshoaei, Brenda Van Wyk

    Published 2025-02-01
    “…Background: Bone marrow and stem cell transplantation have led to significant advancements in modern medicine, offering potential cures for various hematological disorders and specific cancers. …”
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    Article
  15. 1315

    Penggunaan Obat Antihipertensi pada Pasien Hipertensi Esensial di Poliklinik Ginjal Hipertensi RSUP DR. M. Djamil Tahun 2011 by Heri Fitrianto, Syaiful Azmi, Husnil Kadri

    Published 2014-01-01
    “…<br />Kata kunci: obat antihipertensi, hipertensi, diuretik</p><p>Abstract<br />Hypertension can not be cured and is closely related to a decrease in life expectancy. …”
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    Article
  16. 1316

    Sistem Identifikasi Penyakit Paru Obstruktif Kronik (PPOK) Berdasarkan Suara Paru-Paru Menggunakan Jaringan Saraf Tiruan Berbasis Raspberry Pi by Lindhu Parang Kusuma, Barlian Henryranu Prasetio, Eko Setiawan

    Published 2023-02-01
    “…COPD is a progressive disease that cannot be cured and will get worse over time. One way that is commonly used by doctors to diagnose lung conditions is to use a stethoscope. …”
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    Article
  17. 1317

    Analisis Tren dan Perkiraan Pandemi COVID-19 di Indonesia Menggunakan Peramalan Metode Prophet :Sebelum dan Sesudah Aturan New Normal by Mawaddah Harahap, Ahmad Zaki Andika, Amir Mahmud Husein, Abdi Dharma

    Published 2022-02-01
    “…This paper aims to facilitate a comparison between the PSBB and New Normal regulations on the development of the number of Covid-19 cases in Indonesia by mapping the cumulative number of cases (active, cured, confirmed and death cases). The Prophet method is used to predict confirmed cases and deaths within the next 30 days. …”
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    Article
  18. 1318

    CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma by Victoria Jennings, Kevin Harrington, Hardev Pandha, Alan Melcher, Adel Samson, Fiona Errington-Mais, Victoria Roulstone, Eva Crespo-Rodriguez, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Martin McLaughlin, Malin Pedersen, Richard Vile, Joan Kyula, Jehanne Hassan, Lizzie Appleton, Charleen ML Chan Wah Hak, Gabby Baker, Edward Armstrong, Matthew Chiu, Masahiro Ono

    Published 2022-03-01
    “…Targeting CD25 high, antigen-engaged Treg with a depleting anti-CD25 ICI, achieved complete cures in 100% of mice with triple therapy. Transcriptomic analysis confirmed reduction in Foxp3 on addition of anti-CD25 to HSV/BRAFi, as well as increases in expression of genes reflecting interferon signaling and cytotoxic activity.Conclusions Combination HSV/BRAFi is an immunogenic therapy for BRAF mutant melanoma, but cannot fully control tumors. …”
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    Article
  19. 1319

    Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity by Congcong Zhang, Anja Waldmann, Winfried S Wels, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Nina Müller, Pranav Oberoi

    Published 2021-10-01
    “…In an immunocompetent mouse glioblastoma model mimicking low or absent NKG2DL expression, the combination of NKAR-NK-92 cells and NKAB-ErbB2 effectively suppressed outgrowth of ErbB2-positive tumors, resulting in treatment-induced endogenous antitumor immunity and cures in the majority of animals.Conclusions Our results demonstrate that combining an NKAB antibody with effector cells expressing an activating NKAR receptor represents a powerful and versatile approach to simultaneously enhance tumor antigen-specific as well as NKG2D-CAR and natural NKG2D-mediated cytotoxicity, which may be particularly useful to target tumors with heterogeneous target antigen expression.…”
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    Article
  20. 1320

    Elevated D-dimer on admission may predict poor prognosis in childhood influenza associated encephalopathy by Huizhen Wang, Lingkong Zeng, Xingfeng Cheng, Hui Li, Hong Zhang, Yuanmei Shi, Yong Zhang, Changjian Li

    Published 2025-01-01
    “…In the univariate analysis, the poor prognosis group compared with the clinically cured group showed a significant increase in the number of days of hospitalization (3.0 vs. 9.5 days, P < 0.001), high-sensitivity C-reactive protein (6.80 vs. 1.88 mg/L, P = 0.003), interleukin-6 (20.26 vs. 8.24 pg/mL, P = 0.001), interleukin-10 (11.75 vs. 4.72 pg/mL, P = 0.003), alanine aminotransferase (104.0 vs. 20.0 U/L, P = 0.011), aspartate azelotransferase (186.5 vs. 37.0 U/L, P = 0.003), serum albumin (37.99 vs. 40.76 g/L, P = 0.042), prothrombin time (13.2 vs. 11.4 s, P = 0.017), D-dimer (4.34 vs. 0.44 mg/L FEU, P < 0.001), peripheral blood CD19 B-cell count (35.11 vs. 32.75 cells/µL, P = 0.018), and cerebrospinal fluid chloride (126.82 vs. 125.50 mmol/L, P = 0.027) were statistically different in the above 11 indicators. …”
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