Identification of a binding site for small molecule inhibitors targeting human TRPM4 by Babatunde Ekundayo, Prakash Arullampalam, Christian E. Gerber, Anne-Flore Hämmerli, Sabrina Guichard, Mey Boukenna, Daniela Ross-Kaschitza, Martin Lochner, Jean-Sebastien Rougier, Henning Stahlberg, Hugues Abriel, Dongchun Ni

Get full text

Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats by J. Bryan Iorgulescu, Samik P. Patel, Jack Louro, Christian M. Andrade, Andre R. Sanchez, Damien D. Pearse

Get full text

Yiqi Juanshen decoction alleviates renal interstitial fibrosis by targeting the LOXL2/PI3K/AKT pathway to suppress EMT and inflammation by Kaiyue Tan, Jingwei Deng, Yi Liu, Yudi Zhang, Yu Xiong, Su Yuan, Jun Liu, Zhiwei Chen, Yuanyuan Liu, Wenfu Cao

Get full text

Noninferiority trial in veal calves on the efficacy of oxytetracycline and florfenicol treatment for pneumonia guided by quick thoracic ultrasound by Stan Jourquin, Florian Debruyne, Laurens Chantillon, Thomas Lowie, Randy Boone, Jade Bokma, Bart Pardon

“…Regression of maximum consolidation depth <1 cm was used as a criterion for cure and to stop antimicrobial treatment. Additionally, the study assessed the associations of consolidation depth at treatment initiation with cure and treatment duration. …”
Get full text

Phase I study of intratumoral administration of CV8102 in patients with advanced melanoma, squamous cell carcinoma of the skin, squamous cell carcinoma of the head and neck, or ade... by Lucie Heinzerling, Michael Fluck, Caroline Robert, Celeste Lebbe, Erika Richtig, Sven D Koch, Ulrike Gnad-Vogt, Tobias Seibel, Thomas Eigentler, Juan Martin-Liberal, Sebastian Ochsenreither, Peter Mohr, Patrick Terheyden, Carsten Weishaupt, Michael Erdmann, Lukas Koch, Ainara Soria, Igor Samoylenko, Jürgen Krauß, Peter Brossart, Franz Georg Bauernfeind, Marina Gonzalez, Peter Wengenmayer, Ioannis Thomas, Artem Poltoratskiy, Marina Sekacheva, Beate Schmitt-Bormann, Gianluca Quintini, Martin Falk, Paula Codó, Arjun Oberoi, Jana Hess, Yulia Semiletova, Casilda Llacer Perez, Oliver Schönborn-Kellenberger

Get full text

Is Light-Induced Fluorescence Better Than the Endoscopist’s Eye? by Norman E Marcon

“…While recognizing advanced tumours with endoscopy does not generally pose a challenge, cure rates are relatively low, depending on the size and stage of the tumour. …”
Get full text

Comparison of the Efficacy and Safety of Two Cryotherapy Protocols in the Treatment of Common Viral Warts: A Prospective Observational Study by Jihan M. Muhaidat, Firas A. Al-qarqaz, Diala M. Alshiyab, Hadeel S. Alkofahi, Yousef Khader, Mawaddah Y. Ababneh

“…Group 1 patients achieved higher cure rate than group 2, 77.8% and 54.3%, respectively (P=0.001). …”
Get full text

Structural characterization and immunomodulatory activity of polysaccharides from the flowers of Imperata cylindrica Beauv.var. major (Nees) C.E.Hubb by Honglin He, Haijun Huang, Yunheng Yang, Yi Liu, Ailing Liang, Yao Lei, Chenghuai Tang, Ling Yao, Zhiwei Chen

Get full text

The Use of Antisense-Mediated Inhibition to Delineate The Role of Inflammatory Agents in The Pathophysiology of Spinal Cord Injury by Damien D. Pearse, Francisco C. Pereira, Katina Chatzipanteli, Francisco W. Dalton Dietrich, Mary Bartlett Bunge

Get full text

Allergy to Prolene Sutures in a Dural Graft for Chiari Decompression by Iahn Cajigas, S. Shelby Burks, Joanna Gernsback, Lauren Fine, Baharak Moshiree, Allan D. Levi

Get full text

The Impact of Interferon Lambda 3 Gene Polymorphism on Natural Course and Treatment of Hepatitis C by F. Bellanti, G. Vendemiale, E. Altomare, G. Serviddio

Get full text

Mathematical Modelling of Disease Outbreak by Favour Christian, Matthew Molloy

“…The final model included a cure for the zombies, and more susceptible individuals survived proportional to the value assigned to the rate of the spread of the cure. …”
Get full text

Helicobacter pylori: Novel Therapies by Eric Drouin

“…The ideal therapy for Helicobacter pylori would cure the infection without resulting in the development of antibiotic resistance. …”
Get full text

Minimally Invasive Direct Repair of Bilateral Lumbar Spine Pars Defects in Athletes by Gabriel A. Widi, Seth K. Williams, Allan D. Levi

Get full text

Comparative efficacy and safety of co-amoxiclav, cefpodoxime proxetil, and levofloxacin in patients with acute uncomplicated bacterial tonsillitis: A prospective, open-label, paral... by Suja Xaviar, K. Girish, B. Jagannath, Saibal Das, Probin Joseph

“…The efficacy was assessed by subjective clinical improvement and objective bacteriological cure at the end of treatment. Safety was assessed by monitoring adverse events during the study period. …”
Get full text

UJI EFEKTIVITAS EKSBIMA SEBAGAI SUBTITUTOR SIDABAS 500 SC TERHADAP HAMA THRIPS (Thrips sp) PADA TANAMAN CABAI RAWIT (Capsicum frutescens L.) by Sri Utami, Mochamad Soeprijadi Djoko Laksana

“…Research to determine the effectiveness of the extract against diseases curly terms of cure rates and yields of crops cayenne pepper (Capsicum frutescens l.) …”
Get full text

Efficacy and Safety of Oral Itraconazole and Griseofulvin versus Itraconazole Alone in Patients with Tinea Corporis and Cruris Infection: A Comparative Clinical Study by Yagub Salem Saleh, Bassim I. Mohammad, Thamir A. Kubaisi

“…The marked cure was 4 (7.2%) in Group I, whereas 17 (31%) in Group II. …”
Get full text

Comparison of Oral Zinc Sulfate with Systemic Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis by Mohamad Javad Yazdanpanah, Mahnaz Banihashemi, Fakhrozaman Pezeshkpoor, Mohammad Khajedaluee, Sororozaman Famili, Iman Tavakoli Rodi, Hadis Yousefzadeh

“…Serious side effects resulting in treatment discounting occurred in only meglumine antimoniate group. Although cure rate of systemic meglumine antimoniate group was better the treatment with zinc sulfate is much easier, cheaper, more convenient in consumption, safer, and nearly close cure percentage to systemic meglumine antimoniate injections without serious side effect.…”
Get full text

Predictive Factors, Treatment, and Outcomes of Coagulase-Negative Staphylococcal Peritonitis in Malaysian Peritoneal Dialysis Patients: A Single-Center Study by Siew Yan Lau, Boon Cheak Bee, Hin-Seng Wong, Marhanis Salihah Omar, Norazlah Bahari

“…CoNS episodes that were treated with beta-lactam-based or vancomycin-based therapy had a similar primary response rate and complete cure rate. The rates of relapse and repeat were 12% and 16%, respectively. …”
Get full text

Ceftazidime–avibactam for the Treatment of Intra-abdominal Sepsis and Urosepsis: A Retrospective Hospital-based Study in India by Prachee Sathe, Chitra Lele, Simran Chandra, Tatyasaheb Jadhav, Durgesh Makwana, Devidas Bhalerao

“…We observed clinical success, defined a priori, by day 14 in 58.5% of patients and microbiological cure in 61.3%. Most patients (97.0%) did not have recurrent infections. …”
Get full text